HIV type 1 molecular epidemiology in pol and gp41 genes among naive patients from mato Grosso do sul State, Central Western Brazil

AIDS Research and Human Retroviruses

Volumn 28, Issue 3, 2012, Pages 304-307

  Da Silveira, Alexsander Augusto ^a   Cardoso, Ludimila Paula Vaz ^a   Francisco, Roberta Barbosa Lopes ^b   De Araújo Stefani, Mariane Martins ^a  

^a FEDERAL UNIVERSITY OF GOIÁS   (Brazil)

^b LACEN of Campo Grande City   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ENFUVIRTIDE; GLYCOPROTEIN GP 41; PROTEINASE; RNA DIRECTED DNA POLYMERASE; VIRUS ENVELOPE PROTEIN;

ADULT; ARTICLE; BRAZIL; CLINICAL ARTICLE; FEMALE; HOMOSEXUALITY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; MALE; MOLECULAR EPIDEMIOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; VIRAL GENETICS; VIRUS GENE; VIRUS MUTATION; VIRUS RECOMBINANT; VIRUS RESISTANCE;

ADULT; BRAZIL; DRUG RESISTANCE, MULTIPLE, VIRAL; FEMALE; GENETIC VARIATION; GENOTYPE; HIV ENVELOPE PROTEIN GP41; HIV SEROPOSITIVITY; HIV-1; HUMANS; MALE; MIDDLE AGED; MOLECULAR EPIDEMIOLOGY; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; PHYLOGENY; POL GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; RNA, VIRAL; SEQUENCE ANALYSIS, DNA;

EID: 84858140938     PISSN: 08892229     EISSN: 19318405     Source Type: Journal    
DOI: 10.1089/aid.2011.0128     Document Type: Article

References (14)

1. Inocencio LA, Pereira AA, Sucupira MC, et al.: Brazilian Network for HIV Drug Resistance Surveillance: A survey of individuals recently diagnosed with HIV. J Int AIDS Soc 2009;12:20.
2. Sá Filho DJ, Sucupira MC, Caseiro MM, Sabino EC, Diaz RS, and Janini LM: Identification of two HIV type 1 circulating recombinant forms in Brazil. AIDS Res Hum Retroviruses 2006;22:1-13. (Pubitemid 43201511)
3. Santos AF, Sousa TM, Soares EA, et al.: Characterization of a new circulating recombinant form comprising HIV-1 subtypes C and B in southern Brazil. AIDS 2006;20:2011-2019. (Pubitemid 44611054)
4. Guimarães ML, Eyer-Silva WA, Couto-Fernandez JC, and Morgado MG: Identification of two new CRF-BF in Rio de Janeiro State, Brazil. AIDS 2008;22:433-435.
5. Eyer-Silva WA, Couto-Fernandez JC, Silva-de-Jesus C, and Morgado MG: Prevalence of HIV type 1 drug resistance mutations in treatment-naive and experienced patients from resource-limited settings with universal access to anti-retroviral therapy: A survey in two small Brazilian cities. Mem Inst Oswaldo Cruz 2008;103:143-149. (Pubitemid 351535008)
6. Cardoso LP, Queiroz BB, and Stefani MM: HIV-1 pol phy-logenetic diversity and antiretroviral resistance mutations in treatment naive patients from Central West Brazil. J Clin Virol 2009;46:134-139.
7. Carvalho BC, Cardoso LV, Damasceno S, and Stefani MM: Moderate prevalence of transmitted drug resistance and interiorization of HIV-1 subtype C in the Inland North State of Tocantins, Brazil. AIDS Res Hum Retroviruses. 2011. Epub ahead of print; DOI: 10.1089/aid.2010-0334.
8. Shafer RW: Genotypic testing for human immunodeficiency virus type 1 drug resistance. Clin Microbiol Rev 2002;15: 247-277. (Pubitemid 34303765)
9. Sprinz E, Netto EM, Patelli M, et al.: Primary antiretroviral drug resistance among HIV type 1-infected individuals in Brazil. AIDS Res Hum Retroviruses 2009;25:861-867.
10. Derdeyn CA, Decker JM, Sfakianos JN, et al.: Sensitivity of human immunodeficiency virus type 1 to fusion inhibitors targeted to the gp41 first heptad repeat involves distinct regions of gp41 and is consistently modulated by gp120 interactions with the coreceptor. J Virol 2001;75:8605-8614. (Pubitemid 32768965)
11. Cardoso LPV and Stefani MM: High level of multidrug resistance mutations in HIV type 1 pol gene and resistance-associated mutations to enfuvirtide (T-20) among antiretroviral-experienced patients from central Brazil. AIDS Res Hum Retroviruses 2009;25:943-950.
12. Peuchant O, Capdepont S, Ragnaud JM, et al.: Primary resistance to enfuvirtide (T20) in recently HIV-1 infected, antiretroviral-naive patients from the ANRS Aquitaine Cohort. Antivir Ther 2007;12:559-562. (Pubitemid 47041155)
13. Carmona R, Perez-Alvarez L, Munoz M, et al.: Natural resistance- associated mutations to enfuvirtide (T20) and polymorphisms in the gp41 region of different HIV-1 genetic forms from T20 naive patients. J Clin Virol 2005;32: 248-253. (Pubitemid 40255095)
14. Oliveira ACA, Martins AN, Pires AFNPC, et al.: Enfurvitide (T-20) resistance-related mutations in HIV type 1 subtypes B, C and F isolates from Brazilian patients failing HAART. AIDS Res Hum Retroviruses 2009;25:193-198.