Stimulation with a low-amplitude, digitized synaptic signal to invoke robust activity within neuronal networks on multielectrode arrays

BioTechniques

Volumn 52, Issue 3, 2012, Pages 177-182

  Zemianek, Jill M ^a   Serra, Michael ^a   Guaraldi, Mary ^a   Shea, Thomas B ^a  

^a UNIVERSITY OF MASSACHUSETTS LOWELL   (United States)

Author keywords

Multi electrode arrays; Neuronal networks; Synaptic signaling

Indexed keywords

ACCURACY; ACTION POTENTIAL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; ELECTRODE; ELECTROSTIMULATION; EMBRYO; MOUSE; NERVE CELL CULTURE; NERVE CELL NETWORK; NERVE STIMULATION; NEUROMODULATION; NONHUMAN; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION; WAVEFORM;

ANIMALS; CELLS, CULTURED; CEREBRAL CORTEX; ELECTRIC STIMULATION; EQUIPMENT DESIGN; MICE; MICE, INBRED C57BL; MICROELECTRODES; MODELS, NEUROLOGICAL; NERVE NET; NEURONS; SYNAPSES;

EID: 84858130339     PISSN: 07366205     EISSN: 19409818     Source Type: Journal    
DOI: 10.2144/000113823     Document Type: Article

References (32)

1. Jimbo, Y., H.P. Robinson, and A. Kawana. 1998. Strengthening of synchronized activity by tetanic stimulation in cortical cultures: Applications of planar electrode arrays. Biomedical Engineering, IEEE Transactions 45(11):1297-1304.
2. McIntyre, C.C., and W.M. Grill. 1999. Excitation of central nervous system neurons by nonuniform electric fields. Biophys J 76(2):878-888.
3. McIntyre, C.C., and W.M. Grill. 2002. Extracellular stimulation of central neurons: Influence of stimulus waveform and frequency of neuronal output. J Neurophysiol 88(4):1592-1604.
4. Shepherd, R.K., and E. Javel. 1999. Electrical stimulation of the auditory nerve: II. Effect of stimulus waveshape on single fibre response properties. Hearing Research 130(1-2):171-188.
5. Sekirnjak, C., P. Hottowy, A. Sher, W. Dabrowski, A.M. Litke, and E.J. Chichilnisky. 2006. Electrical stimulation of mammalian retinal ganglion cells with multielectrode arrays. J Neurophysiol 95(6):3311-3327.
6. Wagenaar, D.A., and S.M. Potter. 2004. A versatile all-channel stimulator for electrode arrays, with real-time control. Journal of Neural Engineering 1(1):39-45.
7. Wagenaar, D.A., J. Pine, and S.M. Potter. 2004. Effective parameters for stimulation of dissociated cultures using multi-electrode arrays. Journal of Neuroscience Methods 138(1-2):27-37.
8. Brewer, G.J., M.D. Boehler, A. N. Ide, and B. C. Wheeler. 2009. Chronic electrical stimulation of cultured hippocampal networks increases spontaneous spike rates. J. Neurosci. Methods 184(1):104-109.
9. Bakkum, D.J, Z.C. Chao, and S.M. Potter. 2008. Spatio-temporal electrical stimuli shape behavior of an embodied cortical network in a goal-directed learning task. J Neural Eng. 5(3):1741-2552.
10. Le Feber, J., J. Stegenga, and J. Rutten. 2010. The Effect of Slow Electrical Stimuli to Achieve Learning in Cultured Networks of Rat Cortical Neurons. PloS ONE 5(1):e8871.
11. Vadja, I., J. Van Pelt, P. Wolters, M. Chiappalone, S. Martinoia, E. van Someren, and A. van Ooyen. 2008. Low-frequency stimulation induces stable transitions in stereotypical activity in cortical networks. Biophys J 94(12):5028-5039.
12. Ross, J.D., N.E. Reddy, D.J. Bakkum, S.M. Potter, and S.P. DeWeerth. 2007. Experimental platform for the study of region specfici excitation and inhibition in neural tissue. Conf Proc IEEE Eng Med Biol Soc: 4759-4762.
13. Wagenaar, D.A., and S.M. Potter. 2002. Real-time multi-channel stimulus artifact supression by local curve fitting. Journal of Neuroscience Methods 120(2):113-120.
14. Hayt, W.H., and J.A. Buck. 2006. Engineering electromagnetics. Boston: McGraw-Hill Higher Education.
15. Kalluri, D.K. 1999. Electromagnetics of complex media: Frequency shifting by a transient magnetoplasma medium. Boca Raton: CRC Press.
16. Keener, J.P., and T.J. Lewis. 1999. The biphasic mystery: Why a biphasic shock is more effective than a monophasic shock for defibrillation. J Theor Biol 200(1):1-17.
17. Serra, M., M. Dubey, A. Chan, V. Gilman, and T.B. Shea. 2008a. A Low-cost data aquistion interface for multi-electrode array culture systems. Biotechniques 45:451,453-454,456.
18. Kamioka, H., E. Maeda, Y. Jimbo, H.C. Robinson, and A. Kawana. 1996. Spontaneous periodic synchronized bursting during formation of mature patterns in cortical cultures. Neuroscience Letters 206(2-3): 109-112.
19. Serra, M., M. Guaraldi, and T.B. Shea. 2010. Inhibitory neurons modulate spontaneous signaling in cultured cortical neurons: density-dependent regulation of excitatory neuronal signaling. Phys Biol 7: 026009.
20. Lin, S. 1998. Undersampling method and its application in developing a digital spectral wattmeter with power quality monitoring. Northeastern University, Boston, MA: Northeastern University, Boston, MA.
21. nd International IEEE EBMS Conference on Neural Engineering.
22. Serra, M., and T.B. Shea. 2009. Apple juice stimulates organized synaptic activity in cultured cortical neurons. Current Topics Nutraceutical Res 7:93-96.
23. Serra, M., A. Chan, M. Dubey, V. Gilman, and T.B. Shea. 2008b. Folate and S-adenosymethionine modulate synaptic activity in cultured cortical neurons: differential impact on normal and apolipoprotein E-deficient mice. Phys Biol 5; 44002.
24. Madhavan, R., Z.C. Chao, and S.M. Potter. 2007. Plasticity of recurring spatiotemporal activity patterns in cortical networks. Phys Biol 4:181-193.
25. Rolston, J.D., D.A. Wagenaar, and S.M. Potter. 2007. Precisely timed spatiotemporal patterns of neural activitgy in dissociated cortical cultures. Neuroscience. 148:294-303.
26. Wagenaar, D., J. Pine, and S.M. Potter. 2006. Searching for plasticity in dissociated cortical cultures on multi-electrode arrays. Journal of Negative Results in Biomedicine 5:16.
27. Maeda, E., Y. Kuroda, H.P.C. Robinson, and A. Kawana. 1998. Modifications of parallel activity elecited by propagating bursts in developing networks of rate cortical neurons. Eur J Neurosce 10: 488-496.
28. van Pelt J., P.S. Wolters, M.A. Corner, E. Rutten WLC, and G.J. Ramakers. 2004. Long-term characterization of firing dynamics of spontaneous bursts in cultured neural networks. IEEE Trans Biomed Eng 51:2051-2062.
29. Yanling Li, Y., W. Zhou, X. Li, S. Zeng, M. Liu, and Q. Luo. 2007. Characterization of synchronized bursts in cultured hippocampal neuronal networks with learning training on microelectrode arrays. Biosens Bioelectron 22(12):2976-2982.
30. Lapish, C.C., D. Durstewitz, L. J. Chandler, and J.K. Seamans. 2008. Successful choice behavior is associated with distinct and coherent network states in anterior cingulate cortex. Proc Natl Acad Sci U S A 105(33): 11963-11968.
31. Eytan, D., N. Brenner, and S. Marom. 2003. Selective adaptation in networks of cortical neurons. The Journal of Neuroscience 23(28): 9349-9356.
32. Pan, L., Alagapan, S., Franca, E., Brewer, G.J., Wheeler, B.C. 2011 Propagation of action potential activity in a predefined microtunnel neural network. J Neural Eng. 8(4):046031.