Development of a validated capillary electrophoresis method for enantiomeric purity control and quality control of levocetirizine in a pharmaceutical formulation

Chirality

Volumn 24, Issue 4, 2012, Pages 276-282

  Deng, Xiaolan ^a   De Cock, Bart ^a   Vervoort, Ruud ^b   Pamperin, Dirk ^b   Adams, Erwin ^a   Van Schepdael, Ann ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b SYNTHON BV   (Netherlands)

Author keywords

capillary electrophoresis; chiral selector; chiral separation; levocetirizine; quality control

Indexed keywords

BETA CYCLODEXTRIN; BORATE SODIUM; BUFFER; LEVOCETIRIZINE; SILICON DIOXIDE;

ACCURACY; ARTICLE; CAPILLARY ELECTROPHORESIS; CHIRALITY; DRUG FORMULATION; DRUG IMPURITY; DRUG PURITY; DRUG STRUCTURE; ELECTRIC POTENTIAL; ENANTIOMER; FACTORIAL DESIGN; LIMIT OF QUANTITATION; PH; PRIORITY JOURNAL; QUALITY CONTROL; SEPARATION TECHNIQUE; TEMPERATURE; VALIDATION PROCESS;

BETA-CYCLODEXTRINS; BUFFERS; CETIRIZINE; CHEMISTRY, PHARMACEUTICAL; ELECTROPHORESIS, CAPILLARY; FILTRATION; HISTAMINE H1 ANTAGONISTS, NON-SEDATING; HYDROGEN-ION CONCENTRATION; LIMIT OF DETECTION; LINEAR MODELS; QUALITY CONTROL; STEREOISOMERISM; TABLETS;

EID: 84858076683     PISSN: 08990042     EISSN: 1520636X     Source Type: Journal    
DOI: 10.1002/chir.21992     Document Type: Article

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