Cooperative genome-wide analysis shows increased homozygosity in early onset Parkinson's Disease

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Simón Sánchez, Javier ^a   Kilarski, Laura L ^b   Nalls, Michael A ^c   Martinez, Maria ^d,e   Schulte, Claudia ^f   Holmans, Peter ^b   Gasser, Thomas ^f   Hardy, John ^g   Singleton, Andrew B ^c   Wood, Nicholas W ^g   Brice, Alexis ^h,i,j   Heutink, Peter ^a   Williams, Nigel ^b   Morris, Huw R ^b  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b CARDIFF UNIVERSITY SCHOOL OF MEDICINE   (United Kingdom)

^c NATIONAL INSTITUTE ON AGING   (United States)

^d France   (France)

^e UNIVERSITÉ DE TOULOUSE   (France)

^f GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^g UNIVERSITY COLLEGE LONDON   (United Kingdom)

^h SORBONNE UNIVERSITÉ   (France)

ⁱ INSERM   (France)

^j CNRS   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CHROMOSOME 19P; COHORT ANALYSIS; CONTROLLED STUDY; EARL ONSET PARKINSON DISEASE; FEMALE; GENE; GENE LOCUS; GENE MUTATION; GENETIC ASSOCIATION; GENETIC IDENTIFICATION; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; GENOTYPE; HEREDITY; HOMOZYGOSITY; HUMAN; INBREEDING; MAJOR CLINICAL STUDY; MALE; ONSET AGE; PARK2 GENE; PARK7 GENE; PARKINSON DISEASE; PINK1 GENE; RUNS OF HOMOZYGOSITY; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; AGED; CHROMOSOME 19; DNA SEQUENCE; EUROPE; GENETIC PREDISPOSITION; GENETICS; HOMOZYGOTE; HUMAN GENOME; META ANALYSIS; MIDDLE AGED; RECESSIVE GENE; STATISTICAL MODEL; UNITED STATES;

ADULT; AGED; AGED, 80 AND OVER; CHROMOSOMES, HUMAN, PAIR 19; EUROPE; GENES, RECESSIVE; GENETIC PREDISPOSITION TO DISEASE; GENOME, HUMAN; GENOME-WIDE ASSOCIATION STUDY; HOMOZYGOTE; HUMANS; LOGISTIC MODELS; MIDDLE AGED; PARKINSON DISEASE; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS, DNA; UNITED STATES;

EID: 84858009799     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028787     Document Type: Article

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