Effects of ephedra water decoction and cough tablets containing ephedra and liquorice on CYP1A2 and the pharmacokinetics of theophylline in rats

Phytotherapy Research

Volumn 26, Issue 3, 2012, Pages 470-474

  Tang, Jingling ^a   Zhou, Xiaoyan ^a   Ji, Hongyu ^a   Zhu, Daling ^a   Wu, Linhua ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

CYP1A2; Ephedra water decoction; Herb drug interaction; Maxing cough tablets; Theophylline

Indexed keywords

CAFFEINE; CYTOCHROME P450 1A2; HERBACEOUS AGENT; THEOPHYLLINE;

ACCURACY; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG EFFECT; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME INDUCTION; EPHEDRA; GLYCYRRHIZA; IN VIVO STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PROTEIN EXPRESSION; RAT; REPRODUCIBILITY;

ANIMALS; CAFFEINE; CYTOCHROME P-450 CYP1A2; ENZYME ACTIVATION; ENZYME INHIBITORS; EPHEDRA; GLYCYRRHIZA; LIVER; MALE; RANDOM ALLOCATION; RATS; RATS, WISTAR; TABLETS; THEOPHYLLINE; TIME FACTORS; WATER;

EPHEDRA; RATTUS;

EID: 84858002951     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3565     Document Type: Article

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