Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: A comparative study in transgenic mice and human tissues

Journal of Pathology

Volumn 226, Issue 5, 2012, Pages 723-734

  Aichler, Michaela ^a   Seiler, Christopher ^b   Tost, Monica ^a   Siveke, Jens ^c   Mazur, Pawel K ^c,g   Da Silva Buttkus, Patricia ^a   Bartsch, Detlef K ^d   Langer, Peter ^d   Chiblak, Sara ^e   Dürr, Anna ^f   Höfler, Heinz ^f   Klöppel, Günter ^f   Müller Decker, Karin ^e   Brielmeier, Markus ^a   Esposito, Irene ^a,f  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^d PHILIPPS UNIVERSITY MARBURG   (Germany)

^e GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^f TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^g STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Familial pancreatic cancer; Kras; Mouse model; PanIN; Precursor lesions; Tubular complexes

Indexed keywords

APOMUCIN; BIOLOGICAL MARKER; K RAS PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER TISSUE; CELL CYCLE REGULATION; CELL PROLIFERATION; COMPARATIVE STUDY; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; MOUSE; NONHUMAN; PANCREAS ADENOCARCINOMA; PRIORITY JOURNAL; STEM CELL; TRANSGENIC MOUSE;

ANIMALS; CARCINOMA IN SITU; CARCINOMA, PANCREATIC DUCTAL; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, RAS; GENETIC PREDISPOSITION TO DISEASE; HEREDITY; HUMANS; IMMUNOHISTOCHEMISTRY; METAPLASIA; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEOPLASMS, EXPERIMENTAL; PANCREATIC NEOPLASMS; PEDIGREE; PHENOTYPE; PRECANCEROUS CONDITIONS; TRANSCRIPTION FACTORS; TUMOR MARKERS, BIOLOGICAL;

EID: 84858002179     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.3017     Document Type: Article

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