Substrate utilization by recombinant Yarrowia lipolytica growing on sucrose

Applied Microbiology and Biotechnology

Volumn 93, Issue 4, 2012, Pages 1695-1702

  Moeller, Lucie ^a   Zehnsdorf, Andreas ^a   Aurich, Andreas ^a   Bley, Thomas ^b   Strehlitz, Beate ^a  

^a HELMHOLTZ CENTRE FOR ENVIRONMENTAL RESEARCH UFZ   (Germany)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Recombinant yeast; Substrate utilization; Sucrose; Yarrowia lipolytica

Indexed keywords

CONSUMPTION RATES; GLUCOSE UPTAKE; MIXED SUBSTRATES; RECOMBINANT STRAINS; RECOMBINANT YEAST; SOLE CARBON SOURCE; SUBSTRATE UTILIZATION; SUCROSE DEGRADATION; UPTAKE RATE; WILD TYPES; YARROWIA LIPOLYTICA;

CULTIVATION; DEGRADATION; FRUCTOSE; GLUCOSE; SUGAR (SUCROSE);

SUBSTRATES;

BETA FRUCTOFURANOSIDASE; FRUCTOSE; GLUCOSE; MONOSACCHARIDE; SUCROSE;

BIOCHEMISTRY; BIOLOGICAL UPTAKE; CONCENTRATION (COMPOSITION); CULTIVATION; DEGRADATION; FERMENTATION; GENETICALLY MODIFIED ORGANISM; MICROBIAL ACTIVITY; REACTION RATE; SUBSTRATE; SUCROSE; YEAST;

ARTICLE; CARBON SOURCE; CULTURE MEDIUM; ENZYME SYNTHESIS; FERMENTATION; FUNGUS GROWTH; GLUCOSE TRANSPORT; NONHUMAN; YARROWIA LIPOLYTICA;

BETA-FRUCTOFURANOSIDASE; CARBON; CULTURE MEDIA; FRUCTOSE; GLUCOSE; METABOLIC ENGINEERING; ORGANISMS, GENETICALLY MODIFIED; RECOMBINANT PROTEINS; SUCROSE; YARROWIA;

YARROWIA LIPOLYTICA;

EID: 84857998166     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-011-3681-9     Document Type: Article

References (26)

1. Anastassiadis S, Morgunov IG, Kamzolova SV, Finogenova TV (2008) Citric acid production patent review. Recent Pat Biotechnol 2:107-123. doi:10.2174/187220808784619757
2. Anastassiadis S, Rehm H-J (2006) Citric acid production from glucose by yeast Candida oleophila ATCC 20177 under batch, continuous and repeated batch cultivation. El J Biotechnol 9:26-39. doi:10.2225/vol9-issue1-fulltext-5 (Pubitemid 43200923)
3. André A, Chatzifragkou A, Diamantopoulou P, Sarris D, Philippoussis A, Galiotou-Panayotou M, Komaitis M, Papanikolaou S (2009) Biotechnological conversion of bio-diesel-derived crude glycerol by Yarrowia lipolytica strains. Eng Life Sci 9:468-478. doi:10.1002/elsc.200900063
4. Barth G, Gaillardin C (1997) Physiology and genetics of the dimorphic fungus Yarrowia lipolytica. FEMS Microbiol Rev 19:219-237. doi:10.1111/j.1574- 6976.1997.tb00299.x (Pubitemid 27225687)
5. Berovic M, Legisa M (2007) Citric acid production. Biotechnol Annu Rev 13:303-343. doi:10.1016/S1387-2656(07)13011-8 (Pubitemid 47387128)
6. Bizukojc M, Ledakowicz S (2004) The kinetics of simultaneous glucose and fructose uptake and product formation by Aspergillus niger in citric acid fermentation. Process Biochem 39:2261-2268. doi:10.1016/j.procbio.2003.11.017 (Pubitemid 39123626)
7. Crolla A, Kennedy KJ (2001) Optimization of citric acid production from Candida lipolytica Y-1095 using n-paraffin. J Biotechnol 89:27-40. doi:10.1016/S0168-1656(01)00278-4 (Pubitemid 32709991)
8. Förster A, Aurich A, Mauersberger S, Barth G (2007) Citric acid production from sucrose using a recombinant strain of the yeast Yarrowia lipolytica. Appl Microbiol Biotechnol 1409. doi:10.1007/s00253-007-0958-0
9. Kamzolova SV, Finogenova TV, Morgunov IG (2008) Microbiological production of citric and isocitric acids from sunflower oil. Food Technol Biotechnol 46:51-59, ISSN 1330-9862
10. Kruse K, Förster A, Mauersberger S, Barth G (2004) Method for the biotechnological production of citric acid by means of a genetically modified yeast Yarrowia lipolytica. Patent WO2004/009828, DE10333144
11. + transformants. Bioresour Technol 102:6982-6989. doi:10.1016/j.biortech.2011.04.032
12. Mattey M, Kristiansen B (1999) A brief introduction to citric acid biotechnology. In: Kristiansen B, Matey M, Linden J (eds) Citric acid biotechnology. Taylor & Francis, London, UK, pp 1-9
13. Moeller L, Strehlitz B, Aurich A, Zehnsdorf A, Bley T (2007) Optimization of citric acid production from glucose by Yarrowia lipolytica. Eng Life Sci 7:504-511. doi:10.1002/elsc.200620207 (Pubitemid 350020199)
14. Moeller L, Grünberg M, Zehnsdorf A, Strehlitz B, Bley T (2010) Biosensor online control of citric acid production from glucose by Yarrowia lipolytica using semicontinuous fermentation. Eng Life Sci 10:311-320. doi:10.1002/elsc.200900073
15. Moeller L (2010) Optimierung der Citronensäureherstellung mit der Hefe Yarrowia lipolytica unter Verwendung einer Biosensoronline- Regelung. Dissertation 07/2010, Helmholtz Centre for Environmental Research - UFZ, ISSN 1860-0387
16. Moeller L, Grünberg M, Zehnsdorf A, Bley T, Strehlitz B (2011) Repeated fed-batch fermentation using biosensor online control for citric acid production by Yarrowia lipolytica. J Biotechnol 153:133-137. doi:10.1016/j.jbiotec.2011.03.013
17. Moresi M (1994) Effect of glucose concentration on citric acid production by Yarrowia lipolytica. J Chem Technol Biotechnol 60:387-395. doi:10.1002/jctb.280600409
18. Papanikolaou S, Aggelis G (2009) Biotechnological valorization of biodiesel derived glycerol waste through production of single cell oil and citric acid by Yarrowia lipolytica. Lipid Technol 21:83-87. doi:10.1002/lite. 200900017
19. Papanikolaou S, Chatzifragkou A, Fakas S, Galiotou-Panayotou M, Komaitis M, Nicaoud J-M, Aggelis G (2009) Biosynthesis of lipids and organic acids by Yarrowia lipolytica strains cultivated on glucose. Eur J Lipid Sci Technol 111:1221-1232. doi:10.1002/ejit.200900055
20. Röhr M, Kubicek CP, Kominek J (1996) Citric acid. In: Rehm HJ, Reed G (eds) Biotechnology, vol 6, 2nd edn. Wiley-VCH, Weinheim, Germany, pp 307-345
21. Rymowicz W, Rywińska A, Gładkowski W (2008) Simultaneous production of citric acid and eryhtritol from crude glycerol by Yarrowia lipolytica Wratislavia K1. Chem Pap 62:239-246. doi:10.2478/s11696-008-0018-y
22. Scheller F, Schubert F (1989) Beiträge zur Forschung. In: Scheller F, Schubert F (eds) Biosensoren, Band 18. Akademie-Verlag, Berlin, Germany, pp 6-81
23. Steinböck F, Choojun S, Held I, Roehr M, Kubicek CP (1994) Characterization and regulatory properties of a single hexokinase from the citric acid accumulating fungus Aspergillus niger. Biochim Biophys Acta 1200:215-223. doi:10.1016/0304-4165(94)90138-4 (Pubitemid 24222798)
24. Stottmeister U, Hoppe K (1991) Organische Genusssäuren. In: Ruttloff H (ed) Lebensmitteltechnologie, Entwicklungen und Aspekte. Akademie-Verlag, Berlin, Germany, pp 516-557
25. Tsao GT, Cao NJ, Du J, Gong CS (1999) Production of multifunctional organic acids from renewable resources. In: Tsao GT (ed) Adv BiochemEng/Biotechnol, vol 65. Springer-Verlag, Berlin, pp 243-280
26. + transformants in sucrose media. Pol J Food Nutr Sci 6/47(4):49-54