Chronic allergic inflammation causes vascular remodeling and pulmonary hypertension in BMPR2 hypomorph and wild-type mice

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Mushaben, Elizabeth M ^a   Hershey, Gurjit Khurana ^a   Pauciulo, Michael W ^a   Nichols, William C ^a   Le Cras, Timothy D ^a  

^a UNIVERSITY OF CINCINNATI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HOUSE DUST ALLERGEN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; METHACHOLINE; SMAD1 PROTEIN; SMAD5 PROTEIN; BMPR2 PROTEIN, MOUSE; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; METHACHOLINE CHLORIDE; PRIMER DNA;

AIRWAY HYPERREACTIVITY; ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL WALL THICKNESS; ARTERIOLE; ARTICLE; BAGG ALBINO MOUSE; BLOOD VESSEL FUNCTION; BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE 2 GENE; BRONCHUS HYPERREACTIVITY; CHRONIC ALLERGIC INFLAMMATION; CHRONIC INFLAMMATION; CONTROLLED STUDY; DISEASE SEVERITY; DUST EXPOSURE; EOSINOPHIL COUNT; GENOTYPE; HEART CATHETERIZATION; HEART RIGHT VENTRICLE PRESSURE; LOSS OF FUNCTION MUTATION; MACROPHAGE; MOUSE; NEUTROPHIL COUNT; NONHUMAN; PHENOTYPIC VARIATION; PROTEIN PHOSPHORYLATION; PULMONARY ARTERY; PULMONARY HYPERTENSION; PULMONARY VASCULAR REMODELING; SYSTOLIC BLOOD PRESSURE; WILD TYPE; ANALYSIS OF VARIANCE; ANIMAL; BLOOD PRESSURE; COMPARATIVE STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; HYPERSENSITIVITY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LUNG LAVAGE; METABOLISM; MUTATION; PATHOLOGY; PHYSIOLOGY; POLYMERASE CHAIN REACTION; PYROGLYPHIDAE; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

MUS; PYROGLYPHIDAE;

ANALYSIS OF VARIANCE; ANIMALS; ARTERIOLES; BLOOD PRESSURE; BLOTTING, WESTERN; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II; BRONCHOALVEOLAR LAVAGE; DNA PRIMERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENOTYPE; HYPERSENSITIVITY; HYPERTENSION, PULMONARY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; METHACHOLINE CHLORIDE; MICE; MICE, INBRED BALB C; MUTATION; POLYMERASE CHAIN REACTION; PYROGLYPHIDAE; SIGNAL TRANSDUCTION;

EID: 84857987240     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032468     Document Type: Article

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