The association of MCIR gene with coat color of Banna Mini-pig Inbred line (BMI)

Journal of Animal and Veterinary Advances

Volumn 11, Issue 4, 2012, Pages 503-508

  Jinlong, Huo ^a,b,c   Hailong, Huo ^a,d   Pei, Wang ^b,c   Yangzhi, Zeng ^c   Heng, Xiao ^a  

^a YUNNAN UNIVERSITY   (China)

^b Key Laboratory of Banna Mini Pig Inbred Line of Yunnan Province   (China)

^c YUNNAN AGRICULTURAL UNIVERSITY   (China)

^d Yunnan Vocational and Technical College of Agriculture   (China)

Author keywords

Banna mini pig inbred line (BMI); China; Coat color; Extension; Melanocortin receptor 1 (MC1R)

Indexed keywords

EID: 84857968681     PISSN: 16805593     EISSN: 1993601X     Source Type: Journal    
DOI: 10.3923/javaa.2012.503.508     Document Type: Article

References (22)

1. Andresson, L,. 2003. Melanocortin receptor variants with phenotypic effect in horce, pig and chicken. Ann. N. Y. Acad. Sci., 994: 313-318.
2. Evert, R.E., J. Rothuizen and B.A. van Oost,. 2000. identification of a premature stop codon in the melanocyte-stimulating hormone recptor gene (MC1R) in labrador and golden retrievers with yellow coat colour. Anim. Genet., 31:194-199.
3. Giuffra, E., J.M.H. Kijas, V. Amarger, O. Carlborga and J.T. Jeona andL. Andersson, 2000. The origin of the domestic pig: Independent domestication and subsequent mtrogression. Genetics, 154: 1785-1791.
4. Gustafsson, A.C., J.M.H. Kijas, A. Alderborn, M. Uhlen, L. Andersson and J. Lundeberg, 2001. Screening and scanning of single nucleotide polymorphisms in the pig melanocortin 1 receptor gene (MC1R) by pyrosequencing. Anim. Biotechnol., 12: 145-153.
5. Harris, I, 1997. Variables in animal based research: Part 1. Phenotypic variability in experimental animals. Anzccart News, 10: 1-8.
6. Jackson, I.J., 1997. Homologous pigmentation mutations in human, mouse and other model organisms. Hum. Mol. Genet, 6: 1613-1624.
7. Kijas, J.M.H., M. Moller, G. Plastow and L. Andersson, 2001. A frameshift mutation in MC1R and a high frequency of somatic reversions cause black spotting in pigs. Genetics, 158: 779-785.
8. Kijas, J.M.H., R. Wales, A. Tornsten, P. Chardon, M. Moller and L. Andersson, 1998. Melanocortin receptor 1 (MC1R) mutations and coat color in pigs. Genetics, 150: 1177-1185.
9. Klungland, H., D.I. Vage, L. Gomez-Raya, S. Adelsteinsson and S. Liens, 1995. The role of melanocyte-stimulating hormone (MSH) receptor in bovine coat color determination. Mammalian Genome, 6: 636-639.
10. Legault, C, 1998. Genetics of Colour Variation. In: The Genetics of the Pig, Rothschild, M.F. and Ruvinsky, A. (Eds.). CAB International, Wallingford, UK., pp: 51-69.
11. Mariani, P., M.J. Moller, B. Hoyheim, L. Marklund, W. Davies, H. Ellegren and L. Andersson, 1996. The extension coat color locus and the loci for blood group O and tyrosine aminotransferase are on pig chromosome 6. J. Hered., 87: 272-276.
12. Marklund, L., M.J. Moller, K. Sandberg and L. Andersson, 1996. A missense mutation in the gene for melanocyte-stimulating hormone receptor (MC1R) is associated with the chestnut coat color in horses. Mammalian Genome, 7: 895-899.
13. Marklund, S., J. Kijas, H. Rodriguez-Martinez, L. Ronnstrand and K. Funa et al, 1998. Molecular basis for the dominant white phenotype in the domestic pig. Genome Res., 8: 826-833.
14. Mountjoy, K.G., L.S. Robbins, M.T. Mortrud and R.D. Cone, 1992. The cloning of a family of genes that encode the melanocortin receptors. Science, 257: 1248-1251.
15. Newton, J.M., A.L. Wilkie, L. He, S.A. Jordan and D.L. Metallinoset et al, 2000. Melanocortin 1 receptor variation in the domestic dog. Mammalian Genome, 11: 24-30.
16. Ollivier, L. and P. Sellier, 1982. Pig genetics: A review. Ann. Genet. Sel. Anim., 14: 481-544.
17. Robbins, L.S., J.H. Nadeau, K.R. Johnson, M.A. Kelly and L. Roselli-Rehfuss et al, 1993. Pigmentation phenotypes of variant Extension locus alleles result from point mutations that alter MSH receptor function. Cell, 72: 827-834.
18. Sambrook, J., E.F. Fritsch, T. Maniatis and P.T. Huang, 2002. Molecular Cloning: A Laboratory Manual. 3rd Edn., Scienc Press, Beijing, China, pp: 16-69.
19. Vage, D.L, H. Klungland, D. Lu and R.D. Cone, 1999. Molecular and pharmacological characterization of dominant black coat color in sheep. Mammalian Genome, 10: 39-43.
20. Vage, D.L, D. Lu, H. Klungland, S. Lien, S. Adalsteinsson and R.D. Cone, 1997. A non-epistatic interaction of agouti and extension in the fox, Vulpes vulpes. Nat. Genet, 15:311-315.
21. Wright, S., 1921. Systems of mating. I. The biometric relations between parent and offspring. Genetics, 6: 111-123.
22. Zeng, R. and Y.Z. Zeng, 2005. Molecular cloning and characterization of SLA-DR genes in the 133-family of the banna mini-pig inbred line. Anim. Genet., 36: 267-269.