Pteridium aquilinum and its ptaquiloside toxin induce DNA damage response in gastric epithelial cells, a link with gastric carcinogenesis

Toxicological Sciences

Volumn 126, Issue 1, 2012, Pages 60-71

  Gomes, Joana ^a,b   Magalhães, Ana ^a   Michel, Valérie ^b   Amado, Inês F ^a,b   Aranha, Paulo ^c   Ovesen, Rikke G ^c   Hansen, Hans C B ^c   Gärtner, Fátima ^a   Reis, Celso A ^a,d   Touati, Eliette ^b  

^a UNIVERSITY OF PORTO   (Portugal)

^b INSTITUT PASTEUR   (France)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d University of Porto   (Portugal)

Author keywords

DNA damage; Environmental factors; Gastric carcinogenesis; Mutation; Ptaquiloside; Pteridium aquilinum

Indexed keywords

CHECKPOINT KINASE 1; PLANT TOXIN; PROTEIN P53; PTAQUILOSIDE;

ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRACKEN FERN; CANCER CELL; CELL DEATH; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; FRAMESHIFT MUTATION; GENE EXPRESSION REGULATION; GENOTOXICITY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; INTESTINE EPITHELIUM CELL; INTRON; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN ANALYSIS; SIGNAL TRANSDUCTION; STOMACH CARCINOGENESIS; WESTERN BLOTTING;

ANIMALIA; EMBRYOPHYTA; FILICOPHYTA; MUS; PTERIDIUM AQUILINUM;

EID: 84857962109     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfr329     Document Type: Article

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