Debunking the myth that whole-genome sequencing infringes thousands of gene patents

Nature Biotechnology

Volumn 30, Issue 3, 2012, Pages 240-244

  Holman, Christopher M ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN GENES;

GENES;

PATENTS AND INVENTIONS;

AMINO ACID SEQUENCE; ARTICLE; DNA MICROARRAY; DNA SEQUENCE; GENE SEQUENCE; GENETIC ANALYSIS; HUMAN GENOME; NONHUMAN; PATENT; PLANT GENOME; PRIORITY JOURNAL;

BRCA1 PROTEIN; GENOME; HUMANS; NEOPLASMS; PATENTS AS TOPIC; SEQUENCE ANALYSIS, DNA;

EID: 84857947311     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.2146     Document Type: Article

References (24)

1. Association for Molecular Pathology v. U.S. Patent and Trademark Office, 653 F.3d 1329 (Fed. Cir. 2011) 〈http://www.patentdocs.org/2011/07/federal- circuitissues-decision-in-amp-v-uspto.html〉 (accessed 16 January 2012).
2. Utility Examination Guidelines, 66 Fed. Reg. 1092 (January 5, 2001).
3. US patents are freely available online from a number of sources, such as the US Patent and Trademark Office website (http://patft.uspto.gov/) and Google Patent (http://www.google.com/patents).
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5. More specifically, they conducted an automated search to identify all US patents reciting the canonical term "SEQ ID NO." in the claims, and wherein the "SEQ ID NO." term is used in conjunction with a specific genetic sequence corresponding to a known human gene. Jensen & Murray's Supporting Online Material, available at http://www.sciencemag.org/cgi/data/310/ 5746/239/DC1/1 (last visited January 16, 2012).
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7. The query employed by Jensen & Murray identified as 'gene patents' patents that claimed proteins by reference to the DNA sequence encoding the protein, or by reference to a SEQ ID NO. that identified not only a DNA sequence, but also the amino acid sequence encoded by the DNA sequence.
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