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Volumn 34, Issue 2, 2012, Pages 129-142

Neurorestoration therapeutics for neurodegenerative and psychiatric disease

Author keywords

Gene therapy; Neurorestoration; Stem cells; Trophic factors

Indexed keywords

ALEMTUZUMAB; ANTIPARKINSON AGENT; ATORVASTATIN; BETA INTERFERON; BETA1A INTERFERON; CENPLACEL L; CERE 120; ERYTHROPOIETIN; GLYCOSIDE; LEUPRORELIN; LITHIUM CARBONATE; METHYLPREDNISOLONE SULEPTANATE; NERVE GROWTH FACTOR; NGN 9076; OCRELIZUMAB; PROSAVIN; RECOMBINANT ERYTHROPOIETIN; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; RECOMBINANT GROWTH HORMONE; TESAMORELIN; UNCLASSIFIED DRUG;

EID: 84857938235     PISSN: 01616412     EISSN: 17431328     Source Type: Journal    
DOI: 10.1179/1743132811Y.0000000069     Document Type: Review
Times cited : (8)

References (54)
  • 2
    • 0003480653 scopus 로고
    • Degeneration and regeneration of the nervous system
    • In: DeFelipe J, Jones EG, editors, New York: Oxford University Press
    • Cajal SRY. Degeneration and regeneration of the nervous system. In: DeFelipe J, Jones EG, editors. Cajal's degeneration and regeneration of the nervous system. New York: Oxford University Press; 1991. pp. 747-50.
    • (1991) Cajal's Degeneration and Regeneration of the Nervous System , pp. 747-750
    • Cajal, S.R.Y.1
  • 3
    • 62449236814 scopus 로고    scopus 로고
    • The biological restoration of central nervous system architecture and function: Part 1-foundations and historical landmarks in contemporary stem cell biology
    • Farin A, Liu CY, Elder JB, Langmoen IA, Apuzzo ML. The biological restoration of central nervous system architecture and function: Part 1-foundations and historical landmarks in contemporary stem cell biology. Neurosurgery 2009;64:15-39.
    • (2009) Neurosurgery , vol.64 , pp. 15-39
    • Farin, A.1    Liu, C.Y.2    Elder, J.B.3    Langmoen, I.A.4    Apuzzo, M.L.5
  • 4
    • 67649849671 scopus 로고    scopus 로고
    • The biological restoration of central nervous system architecture and function: Part 2 - emergence of the realization of adult neurogenesis
    • Farin A, Liu CY, Langmoen IA, Apuzzo ML. The biological restoration of central nervous system architecture and function: Part 2 - emergence of the realization of adult neurogenesis. Neurosurgery 2009;64:581-60.
    • (2009) Neurosurgery , vol.64 , pp. 581-600
    • Farin, A.1    Liu, C.Y.2    Langmoen, I.A.3    Apuzzo, M.L.4
  • 5
    • 70350330790 scopus 로고    scopus 로고
    • Biological restoration of central nervous system architecture and function: Part 3 - stem cell- and cell-based applications and realities in the biological management of central nervous system disorders: Traumatic, vascular, and epilepsy disorders
    • Farin A, Liu CY, Langmoen IA, Apuzzo ML. Biological restoration of central nervous system architecture and function: Part 3 - stem cell- and cell-based applications and realities in the biological management of central nervous system disorders: traumatic, vascular, and epilepsy disorders. Neurosurgery 2009;65:831-59.
    • (2009) Neurosurgery , vol.65 , pp. 831-859
    • Farin, A.1    Liu, C.Y.2    Langmoen, I.A.3    Apuzzo, M.L.4
  • 6
    • 77956986606 scopus 로고    scopus 로고
    • Watching synaptogenesis in the adult brain
    • Kelsch W, Sim S, Lois C. Watching synaptogenesis in the adult brain. Annu Rev Neurosci 2010;33:131-49.
    • (2010) Annu Rev Neurosci , vol.33 , pp. 131-149
    • Kelsch, W.1    Sim, S.2    Lois, C.3
  • 7
    • 68249090535 scopus 로고    scopus 로고
    • Emerging concepts in neural stem cell research: Autologous repair and cell-based disease modelling
    • Koch P, Kokaia Z, Lindvall O, Brüstle O. Emerging concepts in neural stem cell research: autologous repair and cell-based disease modelling. Lancet Neurol 2009;8:819-29.
    • (2009) Lancet Neurol , vol.8 , pp. 819-829
    • Koch, P.1    Kokaia, Z.2    Lindvall, O.3    Brüstle, O.4
  • 8
    • 69249220421 scopus 로고    scopus 로고
    • Stem cell-based cell therapy in neurological diseases: A review
    • Kim SU, de Vellis J. Stem cell-based cell therapy in neurological diseases: a review. J Neurosci Res 2009;87:2183-200.
    • (2009) J Neurosci Res , vol.87 , pp. 2183-2200
    • Kim, S.U.1    de Vellis, J.2
  • 9
    • 77955322849 scopus 로고    scopus 로고
    • The potential involvement of E-cadherin and beta-catenins in meningioma
    • Zhou K, Wang G, Wang Y, Jin H, Yang S, Liu C. The potential involvement of E-cadherin and beta-catenins in meningioma. PLoS One 2010;5:e11231.
    • (2010) PLoS One , vol.5
    • Zhou, K.1    Wang, G.2    Wang, Y.3    Jin, H.4    Yang, S.5    Liu, C.6
  • 10
    • 0142116301 scopus 로고    scopus 로고
    • Motor enrichment and the induction of plasticity before or after brain injury
    • Kleim JA, Jones TA, Schallert T. Motor enrichment and the induction of plasticity before or after brain injury. Neurochem Res 2003;28:1757-69.
    • (2003) Neurochem Res , vol.28 , pp. 1757-1769
    • Kleim, J.A.1    Jones, T.A.2    Schallert, T.3
  • 11
    • 66749173431 scopus 로고    scopus 로고
    • Mechanisms and targets for angiogenic therapy after stroke
    • Navaratna D, Guo S, Arai K, Lo EH. Mechanisms and targets for angiogenic therapy after stroke. Cell Adh Migr 2009;3:216-23.
    • (2009) Cell Adh Migr , vol.3 , pp. 216-223
    • Navaratna, D.1    Guo, S.2    Arai, K.3    Lo, E.H.4
  • 12
    • 33846560665 scopus 로고    scopus 로고
    • The making of successful axonal regeneration: Genes, molecules and signal transduction pathways
    • Raivich G, Makwana M. The making of successful axonal regeneration: genes, molecules and signal transduction pathways Brain Res Rev 2007;53:287-311.
    • (2007) Brain Res Rev , vol.53 , pp. 287-311
    • Raivich, G.1    Makwana, M.2
  • 13
    • 33845676295 scopus 로고    scopus 로고
    • Tissue sparing and functional recovery following experimental traumatic brain injury is provided by treatment with an anti-myelin-associated glycoprotein antibody
    • Thompson HJ, Marklund N, LeBold DG, Morales DM, Keck CA, Vinson M, et al. Tissue sparing and functional recovery following experimental traumatic brain injury is provided by treatment with an anti-myelin-associated glycoprotein antibody. Eur J Neurosci 2006;24:3063-72.
    • (2006) Eur J Neurosci , vol.24 , pp. 3063-3072
    • Thompson, H.J.1    Marklund, N.2    Lebold, D.G.3    Morales, D.M.4    Keck, C.A.5    Vinson, M.6
  • 14
    • 46749124422 scopus 로고    scopus 로고
    • The role of sildenafil in the treatment of stroke
    • Bednar MM. The role of sildenafil in the treatment of stroke. Curr Opin Invest Drugs 2008;9:754-59.
    • (2008) Curr Opin Invest Drugs , vol.9 , pp. 754-759
    • Bednar, M.M.1
  • 15
    • 46049119100 scopus 로고    scopus 로고
    • Signalling pathways with small molecule mimetics and modulators to achieve neuroprotection and regeneration
    • Skaper SD. Signalling pathways with small molecule mimetics and modulators to achieve neuroprotection and regeneration. CNS Neurol Disord Drug Targets 2008;7:45.
    • (2008) CNS Neurol Disord Drug Targets , vol.7 , pp. 45
    • Skaper, S.D.1
  • 16
    • 38149033055 scopus 로고    scopus 로고
    • The 2007 Feinberg lecture: A new road map for neuroprotection
    • Donnan GA. The 2007 Feinberg lecture: a new road map for neuroprotection. Stroke 2008;39:242.
    • (2008) Stroke , vol.39 , pp. 242
    • Donnan, G.A.1
  • 17
    • 80053554135 scopus 로고    scopus 로고
    • Where will new neuroscience therapies come from?
    • Schoepp DD. Where will new neuroscience therapies come from? Nat Rev 2011;10:715-6.
    • (2011) Nat Rev , vol.10 , pp. 715-716
    • Schoepp, D.D.1
  • 20
    • 67349142021 scopus 로고    scopus 로고
    • Neurovascular mechanisms and blood- brain barrier disorder in Alzheimer's disease
    • Bell RD, Zlokovic BV. Neurovascular mechanisms and blood- brain barrier disorder in Alzheimer's disease. Acta Neuropathol 2009;118:103-13.
    • (2009) Acta Neuropathol , vol.118 , pp. 103-113
    • Bell, R.D.1    Zlokovic, B.V.2
  • 21
    • 0038443056 scopus 로고    scopus 로고
    • Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke
    • Chen J, Zhang, ZG, Li Y, Wang Y, Wang L, Jiang H, et al. Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke. Ann Neurol 2003;53:743-51.
    • (2003) Ann Neurol , vol.53 , pp. 743-751
    • Chen, J.1    Zhang, Z.G.2    Li, Y.3    Wang, Y.4    Wang, L.5    Jiang, H.6
  • 23
    • 0036843061 scopus 로고    scopus 로고
    • Sildenafil (Viagra) induces neurogenesis and promotes functional recovery after stroke in rats
    • Zhang R, Wang Y, Zhang L, Zhang Z, Tsang W, Lu M, et al. Sildenafil (Viagra) induces neurogenesis and promotes functional recovery after stroke in rats. Stroke 2002;33:2675-80.
    • (2002) Stroke , vol.33 , pp. 2675-2680
    • Zhang, R.1    Wang, Y.2    Zhang, L.3    Zhang, Z.4    Tsang, W.5    Lu, M.6
  • 24
    • 33750317276 scopus 로고    scopus 로고
    • Tadalafil, a long-acting type 5 phosphodiesterase isoenzyme inhibitor, improves neurological functional recovery in a rat model of embolic stroke
    • Zhang L, Zhang Z, Zhang RL, Cui Y, LaPointe MC, Silver B, et al. Tadalafil, a long-acting type 5 phosphodiesterase isoenzyme inhibitor, improves neurological functional recovery in a rat model of embolic stroke. Brain Res 2006;1118:192-8.
    • (2006) Brain Res , vol.1118 , pp. 192-198
    • Zhang, L.1    Zhang, Z.2    Zhang, R.L.3    Cui, Y.4    Lapointe, M.C.5    Silver, B.6
  • 25
    • 78751580257 scopus 로고    scopus 로고
    • Fluoxetine for motor recovery after acute ischaemic stroke (FLAME): A randomised placebo-controlled trial
    • Chollet F, Tardy J, Albucher JF, Thalamas C, Berard E, Lamy C, et al. Fluoxetine for motor recovery after acute ischaemic stroke (FLAME): a randomised placebo-controlled trial. Lancet Neurol 2011;10:123-30.
    • (2011) Lancet Neurol , vol.10 , pp. 123-130
    • Chollet, F.1    Tardy, J.2    Albucher, J.F.3    Thalamas, C.4    Berard, E.5    Lamy, C.6
  • 26
  • 28
    • 77954622035 scopus 로고    scopus 로고
    • Cell transplantation in Parkinson's disease: Problems and perspectives
    • Allan LE, Petit GH, Brundin P. Cell transplantation in Parkinson's disease: problems and perspectives. Curr Opin Neurol 2010;23:426-32.
    • (2010) Curr Opin Neurol , vol.23 , pp. 426-432
    • Allan, L.E.1    Petit, G.H.2    Brundin, P.3
  • 29
    • 70349751479 scopus 로고    scopus 로고
    • Therapeutic microinjection of autologous adult human neural stem cells and differentiated neurons for Parkinson's disease: Five-year postoperative outcome
    • Lévesque MF, Neuman T, Rezak M. Therapeutic microinjection of autologous adult human neural stem cells and differentiated neurons for Parkinson's disease: five-year postoperative outcome. Open Stem Cell J 2009;1:20-9.
    • (2009) Open Stem Cell J , vol.1 , pp. 20-29
    • Lévesque, M.F.1    Neuman, T.2    Rezak, M.3
  • 30
    • 65649090629 scopus 로고    scopus 로고
    • Human neural stem cell grafts in the spinal cord of SOD1 transgenic rats: Differentiation and structural integration intothe segmental motor circuitry
    • Xu L, Ryugo DK, Pongstaporn T, Johe K, Koliatsos VE. Human neural stem cell grafts in the spinal cord of SOD1 transgenic rats: differentiation and structural integration intothe segmental motor circuitry. J Comp Neurol 2009;514:297-309.
    • (2009) J Comp Neurol , vol.514 , pp. 297-309
    • Xu, L.1    Ryugo, D.K.2    Pongstaporn, T.3    Johe, K.4    Koliatsos, V.E.5
  • 31
  • 33
    • 33644960902 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor stimulates neurogenesis via vascular endothelial growth factor with STAT activation
    • 190-201
    • Jung KH, Chua K, Lee ST. Granulocyte colony-stimulating factor stimulates neurogenesis via vascular endothelial growth factor with STAT activation. Brain Res 2006;1073-1074:190-201.
    • (2006) Brain Res , pp. 1073-1074
    • Jung, K.H.1    Chua, K.2    Lee, S.T.3
  • 34
    • 0035873718 scopus 로고    scopus 로고
    • Nerve growth factor rapidly induces prolonged acetylcholine release from cultured basal forebrain neurons: Differentiation between neuromodulatory and neurotrophic influences
    • Auld DS, Mennicken F, Quirion R. Nerve growth factor rapidly induces prolonged acetylcholine release from cultured basal forebrain neurons: differentiation between neuromodulatory and neurotrophic influences. J Neurosci 2001;21:3375-82.
    • (2001) J Neurosci , vol.21 , pp. 3375-3382
    • Auld, D.S.1    Mennicken, F.2    Quirion, R.3
  • 37
    • 84857931994 scopus 로고    scopus 로고
    • Available from
    • Available from: http://www.clinicaltrials.gov/ct2/show/NCT007 53571?term5cistanche&rank51.
  • 38
    • 47049096574 scopus 로고    scopus 로고
    • Autologous T-cell vaccination for multiple sclerosis: A perspective on progress
    • Vandenbark AA, Abulafia-Lapid R. Autologous T-cell vaccination for multiple sclerosis: a perspective on progress. BioDrugs 2008;22:265-73.
    • (2008) BioDrugs , vol.22 , pp. 265-273
    • Vandenbark, A.A.1    Abulafia-Lapid, R.2
  • 39
    • 34548441655 scopus 로고    scopus 로고
    • Targeting the Nogo-A signalling pathway to promote recovery following acute CNS injury
    • Walmsley AR, Mir AK. Targeting the Nogo-A signalling pathway to promote recovery following acute CNS injury. Curr Pharm Des 2007;13:2470-84.
    • (2007) Curr Pharm Des , vol.13 , pp. 2470-2484
    • Walmsley, A.R.1    Mir, A.K.2
  • 40
    • 20044373442 scopus 로고    scopus 로고
    • Emerging biological roles for erythropoietin in the nervous system
    • Brines M, Cerami A. Emerging biological roles for erythropoietin in the nervous system. Nat Rev Neurosci 2005;6:484-94.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 484-494
    • Brines, M.1    Cerami, A.2
  • 42
    • 77954451709 scopus 로고    scopus 로고
    • Erythropoietin: A multimodal neuroprotective agent
    • Byts N, Siren AL. Erythropoietin: a multimodal neuroprotective agent. Exp Transl Stroke Med 2009;1:1-4.
    • (2009) Exp Transl Stroke Med , vol.1 , pp. 1-4
    • Byts, N.1    Siren, A.L.2
  • 43
    • 84857987656 scopus 로고    scopus 로고
    • Tesamorelin, a growth hormone releasing hormone analogue, improves cognitive function in MCI and healthy aging: Results of a randomized controlled trial
    • Baker L, Borson S, Merriam G, Friedman SD, CraftBars S, Vitiello MV. Tesamorelin, a growth hormone releasing hormone analogue, improves cognitive function in MCI and healthy aging: results of a randomized controlled trial. Alzheimer's Dement 2011;7:S514.
    • (2011) Alzheimer's Dement , vol.7
    • Baker, L.1    Borson, S.2    Merriam, G.3    Friedman, S.D.4    Craftbars, S.5    Vitiello, M.V.6
  • 45
    • 77957357528 scopus 로고    scopus 로고
    • GM-CSF up-regulated in Rheumatoid Arthritis reverses cognitive impairment and amyloidosis in Alzheimer mice
    • Boyd TD, Bennett SP, Mori T, Governatori N, Runfeldt M, Norden M, et al. GM-CSF up-regulated in Rheumatoid Arthritis reverses cognitive impairment and amyloidosis in Alzheimer mice. J Alzheimer's Dis 21:507-518.
    • J Alzheimer's Dis , vol.21 , pp. 507-518
    • Boyd, T.D.1    Bennett, S.P.2    Mori, T.3    Governatori, N.4    Runfeldt, M.5    Norden, M.6
  • 47
    • 80054804774 scopus 로고    scopus 로고
    • An update on gene therapy in Parkinson's disease
    • Witt J, Marks WJ. An update on gene therapy in Parkinson's disease. Curr Neurol Neurosci Rep 2011;11:362-70.
    • (2011) Curr Neurol Neurosci Rep , vol.11 , pp. 362-370
    • Witt, J.1    Marks, W.J.2
  • 48
    • 79951476995 scopus 로고    scopus 로고
    • Bioactivity of AAV2-Neurturin Gene Therapy (CERE- 120): Differences between Parkinson's disease and nonhuman primate brains
    • Bartus RT, Herzog CD, Chu Y, Wilson A, Brown L, Siffert J, et al. Bioactivity of AAV2-Neurturin Gene Therapy (CERE- 120): differences between Parkinson's disease and nonhuman primate brains. Mov Disord 2010;26:27-36.
    • (2010) Mov Disord , vol.26 , pp. 27-36
    • Bartus, R.T.1    Herzog, C.D.2    Chu, Y.3    Wilson, A.4    Brown, L.5    Siffert, J.6
  • 49
    • 70349787032 scopus 로고    scopus 로고
    • Neurotrophic support of midbrain dopaminergic neurons
    • von Bohlen, Halbach O, Unsicker K. Neurotrophic support of midbrain dopaminergic neurons. Adv Exp Med Biol 2009;651:73-80.
    • (2009) Adv Exp Med Biol , vol.651 , pp. 73-80
    • von, B.1    Halbach, O.2    Unsicker, K.3
  • 50
    • 80053309997 scopus 로고    scopus 로고
    • Mesenchymal stem cells primed with valproate and lithium robustly migrate to infarcted regions and facilitate recovery in a stroke model
    • Tsai LK, Wang Z, Munasinghe J, Leng Y, Leeds P, Chuang DM, et al. Mesenchymal stem cells primed with valproate and lithium robustly migrate to infarcted regions and facilitate recovery in a stroke model. Stroke 2011;42:2932-9.
    • (2011) Stroke , vol.42 , pp. 2932-2939
    • Tsai, L.K.1    Wang, Z.2    Munasinghe, J.3    Leng, Y.4    Leeds, P.5    Chuang, D.M.6
  • 51
    • 77950630586 scopus 로고    scopus 로고
    • Specific immune intervention with monoclonal antibodies for the treatment of multiple sclerosis
    • Trebst C, Voss E, Skripuletz T, Stangel M. Specific immune intervention with monoclonal antibodies for the treatment of multiple sclerosis. Curr Med Chem 2010;17:640-50.
    • (2010) Curr Med Chem , vol.17 , pp. 640-650
    • Trebst, C.1    Voss, E.2    Skripuletz, T.3    Stangel, M.4
  • 52
    • 84993790552 scopus 로고    scopus 로고
    • Review: Recombinant human erythropoietin: Novel strategies for neuroprotective/ neuroregenerative treatment of multiple sclerosis
    • Bartels C, Spate K, Krampe H, Ehrenreich H. Review: recombinant human erythropoietin: novel strategies for neuroprotective/ neuroregenerative treatment of multiple sclerosis. Therap Adv Neurol Disord 2008;1:193-206.
    • (2008) Therap Adv Neurol Disord , vol.1 , pp. 193-206
    • Bartels, C.1    Spate, K.2    Krampe, H.3    Ehrenreich, H.4
  • 53
    • 78651379680 scopus 로고    scopus 로고
    • Case report: Safety and efficacy of erythropoietin in traumatic brain injury patients: A pilot randomized trial
    • 2010:Article ID 209848
    • Nirula R, Diaz-Arrastia R, Brasel K, Weigelt JA, Waxman K. Case report: safety and efficacy of erythropoietin in traumatic brain injury patients: a pilot randomized trial. Crit Care Res Pract 2010;2010:Article ID 209848
    • (2010) Crit Care Res Pract
    • Nirula, R.1    Diaz-Arrastia, R.2    Brasel, K.3    Weigelt, J.A.4    Waxman, K.5
  • 54
    • 84857931995 scopus 로고    scopus 로고
    • Erythropoietin: Recent developments in the treatment of spinal cord injury
    • 2011:Article ID 453179
    • Carelli S, Marfia G, Di Giulio AM, Ghilardi G, Gorio A. Erythropoietin: recent developments in the treatment of spinal cord injury. Neurol Res Int 2011;2011:Article ID 453179.
    • (2011) Neurol Res Int
    • Carelli, S.1    Marfia, G.2    di Giulio, A.M.3    Ghilardi, G.4    Gorio, A.5


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