ADAM17 overexpression promotes angiogenesis by increasing blood vessel sprouting and pericyte number during brain microvessel development

International Journal of Developmental Biology

Volumn 55, Issue 10-12, 2011, Pages 961-968

  Lin, Juntang ^a   Lemke, Cornelius ^a   Redies, Christoph ^a   Yan, Xin ^b   Mix, Eilhard ^b   Rolfs, Arndt ^b   Luo, Jiankai ^a,b  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

ADAM17; Angiogenesis; Brain development; Microvessel; Pericyte

Indexed keywords

A DISINTEGRIN AND METALLOPROTEASE 17 PROTEIN; ADAM PROTEIN; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD VESSEL; BRAIN DEVELOPMENT; CELL COMPOSITION; CELL COUNT; CELL PROLIFERATION; CELL STRUCTURE; CHICK EMBRYO; CONTROLLED STUDY; EMBRYO; NONHUMAN; PERICYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ADAM PROTEINS; ANIMALS; BLOOD VESSELS; BRAIN; CELL COMMUNICATION; CHICK EMBRYO; CHICKENS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MICE; MICROCIRCULATION; NEOVASCULARIZATION, PHYSIOLOGIC; PERICYTES; PROTEIN STRUCTURE, TERTIARY; TIME FACTORS;

EID: 84857936085     PISSN: 02146282     EISSN: None     Source Type: Journal    
DOI: 10.1387/ijdb.103210jl     Document Type: Article

References (35)

1. BAUVOIS B. (2004). and Transmembrane proteases in cell growth and invasion: new contributors to angiogenesis? Oncogene 23: 317-329.
2. BERGERS G, andSONG S. (2005). The role of pericytes in blood-vessel formation and maintenance. Neuro Oncol 7: 452-464.
3. BERTOSSI M, GIROLAMO F, ERREDE M, BENAGIANO V, VIRGINTINO D and RONCALI L. (2002). Developmental changes of HT7 expression in the microvessels of the chick embryo brain. Anat Embryol (Berl) 205: 229-233.
4. BLOBEL CP. (2005). ADAMs: key components in EGFR signalling and development. Nat Rev Mol Cell Biol 6: 32-43.
5. CANAULT M, CERTEL K, SCHATZBERG D, WAGNER DD and HYNES RO. (2010) The lack of ADAM17 activity during embryonic development causes hemorrhage and impairs vessel formation. PLoS One 5: e13433.
6. CHOI YK and KIM KW. (2008). Blood-neural barrier: its diversity and coordinated cell-to-cell communication. BMB Rep 41: 345-352.
7. DOMESICK VB and MOREST DK. (1977). Migration and differentiation of ganglion cells in the optic tectum of the chick embryo. Neuroscience 2: 459-475.
8. DORE-DUFFY P. (2008). Pericytes: pluripotent cells of the blood brain barrier. Curr Pharm Des 14: 1581-1593.
9. EDWARDS DR, HANDSLEY MM and PENNINGTON CJ. (2009). The ADAM metalloproteinases. Mol Aspects Med 29: 258-289.
10. GERHARDT H, WOLBURG H and REDIES C. (2000). N-cadherin mediates pericytic-endothelial interaction during brain angiogenesis in the chicken. Dev Dyn 218: 472-479.
11. GODDARD DR, BUNNING RA and WOODROOFE MN. (2001). Astrocyte and endothelial cell expression of ADAM 17 (TACE) in adult human CNS. Glia 34: 267-271.
12. GÖOZ P, GÖOZ M, BALDYS A and HOFFMAN S. (2009). ADAM-17 regulates endothelial cell morphology, proliferation, and in vitro angiogenesis. Biochem Biophys Res Commun 380: 33-38.
13. HAMBURGER V and HAMILTON HL. (1951). A series of normal stages in the development of the chick embryo. Dev Dyn 195: 231-272.
14. KUKITA T, HATA K, KUKITA A and IIJIMA T. (1998) Laminin, a major basement membrane component of the blood vessel, as a negative regulator of osteoclastogenesis. Calcif Tissue Int 63: 140-142.
15. LAI CH and KUO KH. (2005). The critical component to establish in vitro BBB model: Pericyte. Brain Res Rev 50: 258-265.
16. LAVAIL JH and COWAN WM. (1971). The development of the chick optic tectum. I. Normal morphology and cytoarchitectonic development. Brain Res 28: 391-419.
17. Leibovich SJ, Polverini PJ, Shepard HM, Wiseman DM, Shively V, and Nuseir N. Macrophage-induced angiogenesis is mediated by tumour necrosis factor-alpha. Nature 329: 630-632.
18. LUO J, JU MJ and REDIES C. (2006). Regionalized cadherin-7 expression by radial glia is regulated by Shh and Pax7 during chicken spinal cord development. Neuroscience 142: 1133-1143.
19. LUO J and REDIES C. (2005). Ex ovo electroporation for gene transfer into older chicken embryos. Dev Dyn 233: 1470-1477.
20. LUO J, TREUBERT-ZIMMERMANN U and REDIES C. (2004). Cadherins guide migrating Purkinje cells to specific parasagittal domains during cerebellar development. Mol Cell Neurosci 25: 138-152.
21. NEHLS V, DENZER K and DRENCKHAHN D. (1992). Pericyte involvement in capillary sprouting during angiogenesis in situ. Cell Tissue Res 270: 469-474.
22. OZERDEM U and STALLCUP WB. (2003). Early contribution of pericytes to angiogenic sprouting and tube formation. Angiogenesis 6: 241-249.
23. Patan S. Vasculogenesis and angiogenesis as mechanisms of vascular network formation, growth and remodeling. J Neurooncol 50: 1-15.
24. REDIES C, ENGELHART K and TAKEICHI M. (1993). Differential expression of N-and R-cadherin in functional neuronal systems and other structures of the developing chicken brain. J Comp Neurol 333: 398-416.
25. REINMUTH N, LIU W, JUNG YD, AHMAD SA, SHAHEEN RM, FAN F, BUCANA CD, MCMAHON G, GALLICK GE and ELLIS LM. (2001). Induction of VEGF in perivascular cells defines a potential paracrine mechanism for endothelial cell survival. FASEB J 15:1239-41.
26. RISAU W. (1986). Developing brain produces an angiogenesis factor. Proc Natl Acad Sci USA 83: 3855-3859.
27. RISAU W. (1997). Mechanisms of angiogenesis. Nature 386: 671-674.
28. RISAU W and LEMMON V. (1988). Changes in the vascular extracellular matrix during embryonic vasculogenesis and angiogenesis. Dev Biol 125: 441-450.
29. ROBERTS IM. (2002). Iso-butanol saturated water: a simple procedure for increasing staining intensity of resin sections for light and electron microscopy. J Microsc 207: 97-107.
30. RONCALI L, NICO B, RIBATTI D, BERTOSSI M and MANCINI L. (1986). Effects of the chronic hypoxia on the developing blood-brain barrier in the chick embryo optic tectum. J Submicrosc Cytol 18: 537-541.
31. SAHIN U and BLOBEL CP. (2007). Ectodomain shedding of the EGF-receptor ligand epigen is mediated by ADAM17. FEBS Lett 581: 41-44.
32. SKALLI O, ROPRAZ P, TRZECIAK A, BENZONANA G, GILLESSEN D and GABBIANI G. (1986). A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation. J Cell Biol 103: 2787-2796.
33. SWENDEMAN S, MENDELSON K, WESKAMP G, HORIUCHI K, DEUTSCH U, SCHERLE P, HOOPER A, RAFII S and BLOBEL CP. (2008). VEGF-A stimulates ADAM17-dependent shedding of VEGFR2 and crosstalk between VEGFR2 and ERK signaling. Circ Res 103: 916-918.
34. VAN HINSBERGH VW and KOOLWIJK P. (2008). Endothelial sprouting and angiogenesis: matrix metalloproteinases in the lead. Cardiovasc Res 78: 203-212.
35. WESKAMP G, MENDELSON K, SWENDEMAN S, LE GALL S, MA Y, LYMAN S, HINOKI A, EGUCHI S, GUAIQUIL V, HORIUCHI K and BLOBEL CP. (2010) Pathological neovascularization is reduced by inactivation of ADAM17 in endothelial cells but not in pericytes. Circ Res 106: 932-940.