Phenylbutyrate mouthwash mitigates oral mucositis during radiotherapy or chemoradiotherapy in patients with head-and-neck cancer

International Journal of Radiation Oncology Biology Physics

Volumn 82, Issue 4, 2012, Pages 1463-1470

  Yen, Sang Hue ^a,e   Wang, Ling Wei ^a,e   Lin, Yi Hsien ^b   Jen, Yee Min ^c,f   Chung, Yih Lin ^d,e  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b CHENG HSIN GENERAL HOSPITAL   (Taiwan)

^c TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^d KOO FOUNDATION SUN YAT SEN CANCER CENTER   (Taiwan)

^e NATIONAL YANG MING UNIVERSITY   (Taiwan)

^f NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

Author keywords

Head and neck cancer; Histone deacetylase inhibitor; Oral mucositis; Phenylbutyrate; Radiotherapy

Indexed keywords

ADVERSE EVENTS; ANTI-TUMORS; ASSESSMENT SCALE; BODY WEIGHT; CANCER THERAPY; CHEMICAL CHAPERONE; HEAD-AND-NECK CANCER; HISTONE DEACETYLASE INHIBITOR; KAPLAN-MEIER ESTIMATES; LABORATORY DETERMINATIONS; LOCAL CONTROL; MUCOSITIS; ORAL CARE; ORAL MUCOSA; ORAL MUCOSITIS; OVERALL SURVIVAL; PHASE II; PHENYLBUTYRATE; PILOT STUDIES; PLACEBO GROUPS; POTENTIAL RISKS; RADIATION THERAPY ONCOLOGY GROUPS; RANDOMIZED TRIAL; SIDE EFFECT; TUMOR CONTROL; TUMOR PROTECTION; VITAL SIGN; WORLD HEALTH ORGANIZATION;

CHEMORADIOTHERAPY; DISEASES; DRUG PRODUCTS; ONCOLOGY; TUMORS;

RADIOTHERAPY;

4 PHENYLBUTYRIC ACID; CISPLATIN; FLUOROURACIL; MITOMYCIN C; MOUTHWASH; PLACEBO; UFT;

ADULT; ARTICLE; BODY WEIGHT; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURVIVAL; CANCER THERAPY; CLINICAL ARTICLE; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; EATING; FEMALE; HEAD AND NECK CANCER; HUMAN; LABORATORY TEST; MALE; MOUTH INFLAMMATION; MUCOSA INFLAMMATION; PHYSICAL EXAMINATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; VITAL SIGN;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHEMORADIOTHERAPY; CISPLATIN; DOUBLE-BLIND METHOD; EATING; FEMALE; FLUOROURACIL; HEAD AND NECK NEOPLASMS; HISTONE DEACETYLASE INHIBITORS; HUMANS; MALE; MIDDLE AGED; MITOMYCIN; MOUTHWASHES; PHENYLBUTYRATES; PILOT PROJECTS; RADIATION INJURIES; RADIOTHERAPY DOSAGE; STOMATITIS; TAIWAN; TEGAFUR; URACIL; WEIGHT LOSS;

EID: 84857924225     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2011.04.029     Document Type: Article

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