-
1
-
-
80052778711
-
Lovastatin improves cognitive deficits in NF1: Safety and efficacy study
-
Acosta MT, Kardel PG, Walsh KS, Rosenbaum K, Gioia GA, Packer RJ (2011) Lovastatin improves cognitive deficits in NF1: safety and efficacy study. Ped Neurol 45(4):241-245
-
(2011)
Ped Neurol
, vol.45
, Issue.4
, pp. 241-245
-
-
Acosta, M.T.1
Kardel, P.G.2
Walsh, K.S.3
Rosenbaum, K.4
Gioia, G.A.5
Packer, R.J.6
-
2
-
-
52649172327
-
Frequent gains at chromosome 7q34 involving BRAF in pilocytic astrocytoma
-
Bar EE, Lin A, Tihan T, Burger PC, Eberhart CG (2008) Frequent gains at chromosome 7q34 involving BRAF in pilocytic astrocytoma. J Neuropathol Exp Neurol 67(9):878-887
-
(2008)
J Neuropathol Exp Neurol
, vol.67
, Issue.9
, pp. 878-887
-
-
Bar, E.E.1
Lin, A.2
Tihan, T.3
Burger, P.C.4
Eberhart, C.G.5
-
3
-
-
77958498935
-
Reduced striatal dopamine underlies the attention system dysfunction in neurofibromatosis- 1 mutant mice
-
Brown JA, Emnett RJ, White CR et al (2010) Reduced striatal dopamine underlies the attention system dysfunction in neurofibromatosis- 1 mutant mice. Hum Mol Genet 19:4515-4528
-
(2010)
Hum Mol Genet
, vol.19
, pp. 4515-4528
-
-
Brown, J.A.1
Emnett, R.J.2
White, C.R.3
-
4
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
Cancer Genome Atlas Research Network
-
Cancer Genome Atlas Research Network (2008) Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455:1061-1068
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
-
5
-
-
58149375379
-
Spred1 is required for synaptic plasticity and hippocampus-dependent learning
-
Denayer E, Ahmed T, Brems H et al (2008) Spred1 is required for synaptic plasticity and hippocampus-dependent learning. J Neurosci 28:14443-14449
-
(2008)
J Neurosci
, vol.28
, pp. 14443-14449
-
-
Denayer, E.1
Ahmed, T.2
Brems, H.3
-
6
-
-
80052557069
-
Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors
-
De Raedt T, Walton Z, Yecies JL, Li D, Chen Y, Malone CF, Maertens O, Jeong SM, Bronson RT, Lebleu V, Kalluri R, Normant E, Haigis MC, Manning BD, Wong KK, Macleod KF, Cichowski K (2011) Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors. Cancer Cell 20(3):400-413
-
(2011)
Cancer Cell
, vol.20
, Issue.3
, pp. 400-413
-
-
De Raedt, T.1
Walton, Z.2
Yecies, J.L.3
Li, D.4
Chen, Y.5
Malone, C.F.6
Maertens, O.7
Jeong, S.M.8
Bronson, R.T.9
Lebleu, V.10
Kalluri, R.11
Normant, E.12
Haigis, M.C.13
Manning, B.D.14
Wong, K.K.15
Macleod, K.F.16
Cichowski, K.17
-
7
-
-
79953323848
-
Radiographic regression of cranial meningioma in a NF2 patient treated by bevacizumab
-
Goutagny S, Raymond E, Sterkers O, Colombani JM, Kalamarides M (2011) Radiographic regression of cranial meningioma in a NF2 patient treated by bevacizumab. Ann Oncol 22:990-991
-
(2011)
Ann Oncol
, vol.22
, pp. 990-991
-
-
Goutagny, S.1
Raymond, E.2
Sterkers, O.3
Colombani, J.M.4
Kalamarides, M.5
-
8
-
-
78650724753
-
Hippo signaling: Growth control and beyond
-
Halder G, Johnson RL (2011) Hippo signaling: growth control and beyond. Development 138:9-22
-
(2011)
Development
, vol.138
, pp. 9-22
-
-
Halder, G.1
Johnson, R.L.2
-
9
-
-
34848884867
-
T2 hyperintensities in children with neurofibromatosis type 1 and their relationship to cognitive functioning
-
Hyman SL, Gill DS, Shores EA, Steinberg A, North KN (2007) T2 hyperintensities in children with neurofibromatosis type 1 and their relationship to cognitive functioning. J Neurol Neurosurg Psychiatry 78(10):1088-1091
-
(2007)
J Neurol Neurosurg Psychiatry
, vol.78
, Issue.10
, pp. 1088-1091
-
-
Hyman, S.L.1
Gill, D.S.2
Shores, E.A.3
Steinberg, A.4
North, K.N.5
-
10
-
-
79956096479
-
Identification of a progenitor cell of origin capable of generating diverse meningioma histological subtypes
-
Kalamarides M, Stemmer-Rachamimov AO, Niwa-Kawakita M et al (2011) Identification of a progenitor cell of origin capable of generating diverse meningioma histological subtypes. Oncogene 30:2333-2344
-
(2011)
Oncogene
, vol.30
, pp. 2333-2344
-
-
Kalamarides, M.1
Stemmer-Rachamimov, A.O.2
Niwa-Kawakita, M.3
-
11
-
-
70349273655
-
Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras
-
Lauchle JO, Kim D, Le DT et al (2009) Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras. Nature 461:411-414
-
(2009)
Nature
, vol.461
, pp. 411-414
-
-
Lauchle, J.O.1
Kim, D.2
Le, D.T.3
-
12
-
-
76749108011
-
Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4 (DCAF1) in the nucleus
-
Li W, You L, Cooper J et al (2010) Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4 (DCAF1) in the nucleus. Cell 140:477-490
-
(2010)
Cell
, vol.140
, pp. 477-490
-
-
Li, W.1
You, L.2
Cooper, J.3
-
13
-
-
79960809488
-
Mosaic analysis with double markers reveals tumor cell of origin in glioma
-
Liu C, Sage JC, Miller MR et al (2011) Mosaic analysis with double markers reveals tumor cell of origin in glioma. Cell 146:209-221
-
(2011)
Cell
, vol.146
, pp. 209-221
-
-
Liu, C.1
Sage, J.C.2
Miller, M.R.3
-
14
-
-
79953659370
-
Autophagy blockade enhances HDAC inhibitors' pro-apoptotic effects: Potential implications for the treatment of a therapeutic-resistant malignancy
-
Epub 2011 Apr 1
-
Lopez G, Torres K, Lev D (2011) Autophagy blockade enhances HDAC inhibitors' pro-apoptotic effects: potential implications for the treatment of a therapeutic-resistant malignancy. Autophagy 7(4):440-441 (Epub 2011 Apr 1)
-
(2011)
Autophagy
, vol.7
, Issue.4
, pp. 440-441
-
-
Lopez, G.1
Torres, K.2
Lev, D.3
-
15
-
-
79952575099
-
The mental motor and language development of toddlers with neurofibromatosis type 1
-
Lorenzo J, Barton B, Acosta MT, North KN (2011) The mental motor and language development of toddlers with neurofibromatosis type 1. J Pediatr 158:660-665
-
(2011)
J Pediatr
, vol.158
, pp. 660-665
-
-
Lorenzo, J.1
Barton, B.2
Acosta, M.T.3
North, K.N.4
-
16
-
-
79959524651
-
Yes-associated protein 1 is widely expressed in human brain tumors and promotes glioblastoma growth
-
Orr BA, Bai H, Odia Y, Jain D, Anders RA, Eberhart CG (2011) Yes-associated protein 1 is widely expressed in human brain tumors and promotes glioblastoma growth. J Neuropathol Exp Neurol 70:568-577
-
(2011)
J Neuropathol Exp Neurol
, vol.70
, pp. 568-577
-
-
Orr, B.A.1
Bai, H.2
Odia, Y.3
Jain, D.4
Anders, R.A.5
Eberhart, C.G.6
-
17
-
-
67651173054
-
Hearing improvement after bevacizumab in patients with neurofibromatosis type 2
-
Plotkin SR, Stemmer-Rachamimov AO, Barker FG 2nd et al (2009) Hearing improvement after bevacizumab in patients with neurofibromatosis type 2. N Engl J Med 361:358-367
-
(2009)
N Engl J Med
, vol.361
, pp. 358-367
-
-
Plotkin, S.R.1
Stemmer-Rachamimov, A.O.2
Barker II, F.G.3
-
18
-
-
77954405742
-
Corpus callosum morphology and its relationship to cognitive function in neurofibromatosis type 1
-
Pride N, Payne JM, Webster R, Shores EA, Rae C, North KN (2010) Corpus callosum morphology and its relationship to cognitive function in neurofibromatosis type 1. J Child Neurol 25:834-841
-
(2010)
J Child Neurol
, vol.25
, pp. 834-841
-
-
Pride, N.1
Payne, J.M.2
Webster, R.3
Shores, E.A.4
Rae, C.5
North, K.N.6
-
19
-
-
79957880389
-
BRAF activation induces transformation and then senescence in human neural stem cells: A pilocytic astrocytoma model
-
Raabe EH, Lim KS, Kim JM et al (2011) BRAF activation induces transformation and then senescence in human neural stem cells: a pilocytic astrocytoma model. Clin Cancer Res 17:3590-3599
-
(2011)
Clin Cancer Res
, vol.17
, pp. 3590-3599
-
-
Raabe, E.H.1
Lim, K.S.2
Kim, J.M.3
-
20
-
-
80051707037
-
Middle fossa decompression for hearing preservation: A review of institutional results and indications
-
Slattery WH, Hoa M, Bonne N et al (2011) Middle fossa decompression for hearing preservation: a review of institutional results and indications. Otol Neurotol 32:1017-1024
-
(2011)
Otol Neurotol
, vol.32
, pp. 1017-1024
-
-
Slattery, W.H.1
Hoa, M.2
Bonne, N.3
-
21
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
-
Verhaak RG, Hoadley KA, Purdom E et al (2010) Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 17:98-110
-
(2010)
Cancer Cell
, vol.17
, pp. 98-110
-
-
Verhaak, R.G.1
Hoadley, K.A.2
Purdom, E.3
-
22
-
-
83455188403
-
Preclincial testing of Sorafenib and RAD001 in the Nf(flox/flox);DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging
-
doi: 10.1002/pbc.23015
-
Wu J, Dombi E, Jousma E, Scott Dunn R, Lindquist D, Schnell BM, Kim MO, Kim A, Widemann BC, Cripe TP, Ratner N (2011) Preclincial testing of Sorafenib and RAD001 in the Nf(flox/flox);DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging. Pediatr Blood Cancer. doi: 10.1002/pbc.23015
-
(2011)
Pediatr Blood Cancer
-
-
Wu, J.1
Dombi, E.2
Jousma, E.3
Scott Dunn, R.4
Lindquist, D.5
Schnell, B.M.6
Kim, M.O.7
Kim, A.8
Widemann, B.C.9
Cripe, T.P.10
Ratner, N.11
-
23
-
-
54549095884
-
Nf1-dependent tumors require a microenvironment containing Nf1± and c-kit-dependent bone marrow
-
Yang et al (2008) Nf1-dependent tumors require a microenvironment containing Nf1± and c-kit-dependent bone marrow. Cell 135(3):437-448
-
(2008)
Cell
, vol.135
, Issue.3
, pp. 437-448
-
-
Yang1
-
24
-
-
79953753962
-
A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions
-
Yi C, Troutman S, Fera D et al (2011) A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions. Cancer Cell 19:527-540
-
(2011)
Cancer Cell
, vol.19
, pp. 527-540
-
-
Yi, C.1
Troutman, S.2
Fera, D.3
-
25
-
-
77954945373
-
The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals
-
Zhang N, Bai H, David KK et al (2010) The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals. Dev Cell 19:27-38
-
(2010)
Dev Cell
, vol.19
, pp. 27-38
-
-
Zhang, N.1
Bai, H.2
David, K.K.3
|