18F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in the Assessment of Occult Primary Head and Neck Cancers - An Audit and Review of Published Studies

Clinical Oncology

Volumn 24, Issue 3, 2012, Pages 190-195

  Wong, W L ^a   Sonoda, L I ^a   Gharpurhy, A ^a   Gollub, F ^a   Wellsted, D ^b   Goodchild, K ^a   Lemon, C ^a   Farrell, R ^c   Saunders, M ^a,d  

^a MOUNT VERNON HOSPITAL   (United Kingdom)

^b UNIVERSITY OF HERTFORDSHIRE   (United Kingdom)

^c NORTHWICK PARK HOSPITAL   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

FDG; Head and neck cancer; Neck cancer; Neck nodes; Occult primary cancer; PET; PET CT

Indexed keywords

FLUORODEOXYGLUCOSE F 18;

ADULT; AGED; ARTICLE; CANCER LOCALIZATION; CANCER SURVIVAL; COMPUTER ASSISTED EMISSION TOMOGRAPHY; DISEASE COURSE; DRUG UPTAKE; FOLLOW UP; GLOSSITIS; HEAD AND NECK CANCER; HUMAN; LIVER METASTASIS; LUNG CANCER; MAJOR CLINICAL STUDY; PREDICTIVE VALUE; PRIMARY TUMOR; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; TONSILLECTOMY;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; FEMALE; FLUORODEOXYGLUCOSE F18; FOLLOW-UP STUDIES; HEAD AND NECK NEOPLASMS; HUMANS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM STAGING; POSITRON-EMISSION TOMOGRAPHY AND COMPUTED TOMOGRAPHY; PROGNOSIS; RADIOPHARMACEUTICALS; RETROSPECTIVE STUDIES;

EID: 84857911345     PISSN: 09366555     EISSN: 14332981     Source Type: Journal    
DOI: 10.1016/j.clon.2011.11.001     Document Type: Article

References (24)

1. Wong W.L., Saunders M. The impact of FDG PET on the management of occult primary head and neck tumours. Clin Oncol (R Coll Radiol) 2003, 15:461-466.
2. Wong W.L., Saunders M. Role of PET FDG in the management of head and neck squamous cell cancer. Clin Oncol (R Coll Radiol) 1998, 10:361-366.
3. Johansen J., Eigtved A., Buchwald C., et al. Implication of 18F-fluoro-2-deoxy-D-glucose positron emission tomography on management of carcinoma of unknown primary in the head and neck: a Danish cohort study. Laryngoscope 2002, 112:2009-2014.
4. Jungehülsing M., Scheidhauer K., Damm M., et al. 2[F]-fluoro-2-deoxy-D-glucose positron emission tomography is a sensitive tool for the detection of occult primary cancer (carcinoma of unknown primary syndrome) with head and neck lymph node manifestation. Otolaryngol Head Neck Surg 2000, 123:294-2301.
5. Schipper J.H., Schrader M., Arweiler D., et al. [Positron emission tomography for primary tumor detection in lymph node metastases with unknown primary tumor]. HNO 1996, 44:254-257.
6. Bohuslavizki K.H., Klutmann S., Sonnemann U., et al. [F-18 FDG PET for detection of occult primary tumor in patients with lymphatic metastases of the neck region]. Laryngorhinootologie 1999, 78:445-449.
7. Braams J.W., Pruim J., Kole A.C., et al. Detection of unknown primary head and neck tumors by positron emission tomography. Int J Oral Maxillofac Surg 1997, 26:112-115.
8. Safa A.A., Tran L.M., Rege S., et al. The role of positron emission tomography in occult primary head and neck cancers. Cancer J Sci Am 1999, 5:214-218.
9. Regelink G., Brouwer J., de Bree R., et al. Detection of unknown primary tumours and distant metastases in patients with cervical metastases: value of FDG-PET versus conventional modalities. Eur J Nucl Med Mol Imaging 2002, 29:1024-1030.
10. Fogarty G.B., Peters L.J., Stewart J., et al. The usefulness of fluorine 18-labelled deoxyglucose positron emission tomography in the investigation of patients with cervical lymphadenopathy from an unknown primary tumor. Head Neck 2003, 25:138-145.
11. Padovani D., Aimoni C., Zucchetta P., et al. 18-FDG PET in the diagnosis of laterocervical metastases from occult carcinoma. Eur Arch Otorhinolaryngol 2009, 266:267-271.
12. Silva P., Hulse P., Sykes A.J., et al. Should FDG-PET scanning be routinely used for patients with an unknown head and neck squamous primary?. J Laryngol Otol 2007, 121:149-153.
13. Cianchetti M., Mancuso A.A., Amdur R.J., et al. Diagnostic evaluation of squamous cell carcinoma metastatic to cervical lymph nodes from an unknown head and neck primary site. Laryngoscope 2009, 119:2348-2354.
14. Wong W.L., Hussain K., Chevretton E., et al. Validation and clinical application of computer-combined computed tomography and positron emission tomography with 2-[18F]fluoro-2-deoxy-D-glucose head and neck images. Am J Surg 1996, 172:628-632.
15. Gutzeit A., Antoch G., Kühl H., et al. Unknown primary tumors: detection with dual-modality PET/CT - initial experience. Radiology 2005, 234:227-234.
16. Branstetter B.F., Blodgett T.M., Zimmer L.A., et al. Head and neck malignancy: is PET/CT more accurate than PET or CT alone?. Radiology 2005, 235:580-586.
17. Greene FL, Page DL, Fleming ID, et al., editors. AJCC. Cancer Staging Handbook. New York: Springer Verlag; 2002.
18. Moule R.N., Kayani I., Prior T., et al. Adaptive 18fluoro-2-deoxyglucose positron emission tomography/computed tomography-based target volume delineation in radiotherapy planning of head and neck cancer. Clin Oncol (R Coll Radiol) 2011, 23:364-371.
19. Roh J.L., Kim J.S., Lee J.H., et al. Utility of combined (18)F-fluorodeoxyglucose-positron emission tomography and computed tomography in patients with cervical metastases from unknown primary tumors. Oral Oncol 2009, 45:218-224.
20. Wartski M., Le Stanc E., Gontier E., et al. In search of an unknown primary tumour presenting with cervical metastases: performance of hybrid FDG-PET-CT. Nucl Med Commun 2007, 28:365-371.
21. Freudenberg L.S., Fischer M., Antoch G., et al. Dual modality of 18F-fluorodeoxyglucose-positron emission tomography/computed tomography in patients with cervical carcinoma of unknown primary. Med Princ Pract 2005, 14:155-160.
22. Stoeckli S.J., Mosna-Firlejczyk K., Goerres G.W. Lymph node metastasis of squamous cell carcinoma from an unknown primary: impact of positron emission tomography. Eur J Nucl Med Mol Imaging 2003, 30:411-416.
23. Price T., Pickles J. Synchronous bilateral tonsillar carcinoma: role of fluoro-deoxyglucose positron emission tomography scanning in detecting occult primary tumours in metastatic nodal disease of the head and neck. J Laryngol Otol 2006, 120:334-337.
24. Wong W.L., Gibson D., Sanghera B., et al. Evaluation of normal FDG uptake in palatine tonsil and its potential value for detecting occult head and neck cancers: a PET CT study. Nucl Med Commun 2007, 28:675-680.