Ethics of the heart: Ethical and policy challenges in the treatment of advanced heart failure

Perspectives in Biology and Medicine

Volumn 55, Issue 1, 2012, Pages 71-80

  Fields, Anjali V ^a   Kirkpatrick, James N ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84857884563     PISSN: 00315982     EISSN: None     Source Type: Journal    
DOI: 10.1353/pbm.2012.0009     Document Type: Article

References (44)

1. Abraham, W.T., et al. 2002. Cardiac resynchronization in chronic heart failure. N Engl J Med 346:1845-53.
2. Arnold, J. M., et al. 2006. Canadian Cardiovascular Society consensus conference recommendations on heart failure 2006: Diagnosis and management. Can J Cardiol 22: 23-45.
3. Bax, J. J., E. E. Van derWall, and M. J. Schalij. 2002.Cardiac resynchronization therapy for heart failure. N Engl J Med 347:1803-4.
4. Beauchamp, T. L., and J. F. Childress. 2008. Principles of biomedical ethics, 6th ed. Oxford: Oxford Univ. Press.
5. Bernat, J. L., et al. 2010. The circulatory-respiratory determination of death in organ donation. Crit Care Med 38(3):963-70.
6. Buxton, A. E., et al. 1999. A randomized study of the prevention of sudden death in patients with coronary artery disease. Multicenter Unsustained Tachycardia Trial Investigators. N Engl J Med 341:1882-90.
7. Cleland, J.G., et al. 2005.The effect of cardiac resynchronization on morbidity and mortality in heart failure. N Engl J Med 352:1539-49.
8. Goldstein, N., et al. 2010. Brief communication: Management of implantable cardioverter-defibrillators in hospice.A nationwide survey. Ann Intern Med 152(5):296-99.
9. Goodlin, S. J., et al. 2005. Hospice care for heart failure patients. J Pain Symptom Manag 29:525-28.
10. Grady, K. L., A. Jalowiec, and C. White-Williams. 1999. Predictors of quality of life in patients at one year after heart transplantation. J Heart Lung Transplant 18(3):202-10.
11. Grady, K. L., et al. 2004. Longitudinal change in quality of life and impact on survival after left ventricular assist device implantation. Ann Thorac Surg 77:1321-27.
12. Halpern, S. D., et al. 2008. Informing candidates for solid-organ transplantation about donor risk factors. N Engl J Med 358(26):2832-37.
13. Heidenreich, P. A., et al. 2011. Forecasting the future of cardiovascular disease in the United States: A policy statement from the American Heart Association. Circulation 123(8):933-44.
14. Hunt, S.A., et al. 2005.ACC/AHA 2005 Guideline update for the diagnosis and management of chronic heart failure in the adult: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation 112: e154-e235.
15. Irvine, J., et al. 2002. Quality of life in the Canadian Implantable Defibrillator Study (CIDS). Am Heart J 144:282-89.
16. Jiang, W., et al. 2004. Prognostic value of anxiety and depression in patients with chronic heart failure. Circulation 110:3452-56.
17. Kirklin, J. K., et al. 2011.Third INTERMACS annual report: The evolution of destination therapy in the United States. J Heart Lung Transplant 30:115-23.
18. Kirkpatrick, J. N., S. E. Fedson, and R.Verdino. 2007. Ethical dilemmas in device treatment for advanced heart failure. Curr Opin Support Palliat Care 1:267-73.
19. Konstam, V., D. K. Moser, and M. J. De Jong. 2005. Depression and anxiety in heart failure. J Card Fail 11:455-63.
20. Lewis, E. F. 2011. End of life care in advanced heart failure. Curr Treat Options Cardiovasc Med 13:79-89.
21. Linde, C., et al. 2003. Long-term improvements in quality of life by biventricular pacing in patients with chronic heart failure: Results from the Multisite Stimulation in Cardiomyopathy study (MUSTIC). Am J Cardiol 91:1090-95.
22. Lindenfeld, J., et al. 2007. Effects of cardiac resynchronization therapy with or without a defibrillator on survival and hospitalizations in patients with NewYork Heart Association class IV heart failure. Circulation 115:204-12.
23. Lindenfeld, J., et al. 2010. HFSA 2010 comprehensive heart failure practice guideline. J Card Fail 16(6):e1-e194.
24. Lloyd-Jones, D., et al. 2009.Heart disease and stroke statistics: 2009 update.A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 119:480-86.
25. Mark, D. B., et al. 2008.Quality of life with defibrillator therapy or amiodarone in heart failure: Sudden Cardiac Death in Heart Failure Trial Investigators. N Engl J Med 359: 999-1008.
26. Moss, A. J., et al. 2002. Multicenter Automatic Defibrillator Implantation Trial II Investigators: Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction. N Engl J Med 346:877-83.
27. Padeletti, L., et al. 2010. EHRA expert consensus statement on the management of cardiovascular implantable electronic devices in patients nearing end of life or requesting withdrawal of therapy. Europace 12(10):1480-89.
28. Pedersen, S. S., et al. 2008. Clustering of device-related concerns and type D personality predicts increased distress in ICD patients independent of shocks. Pacing Clin Electrophysiol 31:20-27.
29. Pedersen, S. S., et al. 2009. Does ICD indication affect quality of life and levels of distress? Pacing Clin Electrophysiol 32:153-56.
30. Reese, P. P., and A. L. Caplan. 2011. Better off living. Clin J Am Soc Nephrol 6(9):2310-12.
31. Rizzieri, A. G., et al. 2008. Ethical challenges with the left ventricular assist device as a destination therapy. Philos Ethics Humanit Med 3:20.
32. Rogers, J. G., et al. 2010. Continuous flow left ventricular assist device improves functional capacity and quality of life of advanced heart failure patients. J Am Coll Cardiol 55:1826-34.
33. Rose, E.A., et al. 2009.The REMATCH trial: Rationale, design, and end points. Randomized evaluation of mechanical assistance for the treatment of congestive heart failure. Ann Thorac Surg 67:723-30.
34. Sanders, G. D., M. A. Hlatky, and D. K. Owens. 2005. Cost-effectiveness of implantable cardioverter-defibrillators. N Engl J Med 353(14):1471-80.
35. Shamaskin, A. M., et al. 2010. Age differences in adjustment and adherence in a large multi-site sample 5-10 years after heart transplantation. Presentation at the International Congress of Behavioral Medicine,Washington, DC,August 2010.
36. Simon, M.A., et al. 2010. Left ventricular remodeling and myocardial recovery on mechanical circulatory support. J Card Fail 16(2):99-105.
37. Slaughter, M. S., et al. 2009. Advanced heart failure treated with continuous-flow left ventricular assist device. N Engl J Med 361:2241-51.
38. Stevenson, L.W. 2006a.The evolving role of mechanical circulatory support in advanced heart failure. In ISHLT monograph series, ed. O. H. Frasier and J. K. Kirklin, 181-204. NewYork: Elsevier.
39. Stevenson, L.W. 2006b. Implantable cardioverter-defibrillators for primary prevention of sudden death in heart failure:Are there enough bangs for the bucks? Circulation 114: 101-3.
40. Stevenson, L.W., andW. G. Stevenson. 2006. Cost-effectiveness of ICDs. N Engl J Med 354:205-7.
41. Stewart, G.C., et al. 2010. Patient expectations from implantable defibrillators to prevent death in heart failure. J Card Fail 16(2):106-13.
42. Swedberg, K., et al. 2005. Guidelines for the diagnosis and treatment of chronic heart failure: Executive summary (update 2005). Task Force for the Diagnosis andTreatment of Chronic Heart Failure of the European Society of Cardiology. Eur Heart J 26:1115-40.
43. Swetz, K. M., et al. 2011. Palliative medicine consultation for preparedness planning in patients receiving left ventricular assist devices as destination therapy. Mayo Clin Proc 86(6):493-500.
44. U.S. Organ Procurement and Transplantation Network (USOPTN), and the Scientific Registry of Transplant Recipients. 2009. Annual report of the U.S. Organ Procurement and Transplantation Network and the Scientific Registry of Transplant Recipients:Transplant data 1999-2008. Rockville, MD: U.S. Dept. of Health and Human Services, Health Resources and Services Administration, Healthcare S stems Bureau, Division of Transplantation.