Anxiety: A hidden element in dementia

Advances in Psychiatric Treatment

Volumn 18, Issue 2, 2012, Pages 119-128

  Badrakalimuthu, Vellingiri Raja ^a   Tarbuck, Andrew F ^b,c,d  

^a FULBOURN HOSPITAL   (United Kingdom)

^b NORFOLK AND SUFFOLK NHS FOUNDATION TRUST   (United Kingdom)

^c UNIVERSITY OF EAST ANGLIA   (United Kingdom)

^d DeNDRoN East Anglia Research Network   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BUSPIRONE; CARBAMAZEPINE; CHOLINESTERASE INHIBITOR; CLOMIPRAMINE; DIAZEPAM; DONEPEZIL; FLUOXETINE; GALANTAMINE; IMIPRAMINE; MIRTAZAPINE; OXAZEPAM; PLACEBO; PREGABALIN; QUETIAPINE; RISPERIDONE; RIVASTIGMINE; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; TRAZODONE; VALPROIC ACID; VENLAFAXINE; ZALEPLON; ZOLPIDEM; ZOPICLONE;

AGED; AGITATION; AGORAPHOBIA; ALZHEIMER DISEASE; ANXIETY; ANXIETY DISORDER; BONE MARROW TOXICITY; CASE REPORT; CHRONIC OBSTRUCTIVE LUNG DISEASE; COGNITIVE DEFECT; COGNITIVE THERAPY; DEMENTIA; DEPRESSION; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DIZZINESS; DRUG WITHDRAWAL; DYSPHORIA; FINANCIAL MANAGEMENT; GENETIC COUNSELING; HEADACHE; HUMAN; HUNTINGTON CHOREA; INFECTION; INSOMNIA; IRRITABILITY; LEARNING; LOW DRUG DOSE; MEMORY; MENTAL HEALTH SERVICE; METABOLIC SYNDROME X; MULTIINFARCT DEMENTIA; NAUSEA; NEUROIMAGING; PHYSIOTHERAPIST; PROSPECTIVE STUDY; PSYCHOPHARMACOLOGY; QUALITY OF LIFE; RATING SCALE; RESPIRATORY DISTRESS; RESTLESSNESS; REVIEW; SEDATION; SELF REPORT; SIDE EFFECT; SOCIAL WORKER; SOMNOLENCE; UNSPECIFIED SIDE EFFECT; WEIGHT GAIN;

EID: 84857879344     PISSN: 13555146     EISSN: 14721481     Source Type: Journal    
DOI: 10.1192/apt.bp.110.008458     Document Type: Review

References (58)

1. Aarsland D, Cummings JL, Larsen JP (2001) Neuropsychiatric differences between Parkinson's disease with dementia and Alzheimer's disease. International Journal of Geriatric Psychiatry 16: 184-91. (Pubitemid 32166310)
2. Alexopoulos GS, Raue PJ, Dimitris N, et al (2011) Problem-solving therapy and supportive therapy in older adults with major depression and executive dysfunction: effect on disability. Archives of General Psychiatry 68: 33-41.
3. Alzheimer's Society (2011) Assistive technology - devices to help with everyday living. Alzheimer's Society (http://alzheimers.org.uk/site/ scripts/documents-info.php?documentID=109).
4. American Psychiatric Association (1994) Diagnostic and Statistical Manual of Mental Disorders (4th edn) (DSM-IV). APA.
5. Baldwin D, Anderson I, Nutt D, et al (2005) Evidence-based guidelines for the pharmacological treatment of anxiety disorders: recommendations from the British Association for Psychopharmacology. Journal of Psychopharmacology 19: 567-96. (Pubitemid 41578819)
6. Ballard C, Neill D, O'Brien J, et al (2000) Anxiety, depression and psychosis in vascular dementia: prevalence and associations. Journal of Affective Disorders 59: 97-106. (Pubitemid 30317426)
7. Banerjee S, Smith SC, Lamping DL, et al (2006) Quality of life in dementia: more than just cognition. An analysis of associations with quality of life in dementia. Journal of Neurology, Neurosurgery and Psychiatry 77: 146-8. (Pubitemid 43220831)
8. Beekman AT, Bremmer MA, Deeg DJH, et al (1998) Anxiety disorders in later life: a report from the longitudinal aging study Amsterdam. International Journal of Geriatric Psychiatry 13: 717-26. (Pubitemid 28491262)
9. Bierman EJM, Comijs HC, Jonker C, et al (2009) The effect of anxiety and depression on decline of memory function in Alzheimer's disease. International Psychogeriatrics 21: 1142-7.
10. Bjelland I, Dahl AA, Haug TT, et al (2002) The validity of hospital anxiety and depression scale: an updated literature review. Journal of Psychosomatic Research 52: 69-77. (Pubitemid 34192886)
11. Bohm C, Robinson DS, Gammans RE, et al (1990) Buspirone therapy in anxious elderly patients: a controlled clinical trial. Journal of Clinical Psychopharmacology 10: 47S-51S. (Pubitemid 20212930)
12. Chen JC, Borson S, Scanlan JM (2000) Stage-specific prevalence of behavioural symptoms in Alzheimer's disease in multi-ethnic community sample. American Journal of Geriatric Psychiatry 8: 123-33. (Pubitemid 30226962)
13. Cohen D, Luchins D, Eisdorfer C, et al (1990) Caring for relatives with Alzheimer's disease: the mental health risks to spouses, adult children and other family caregivers. Behavior, Health, and Aging 1: 171-82.
14. Cohen-Mansfield J, Billig N (1986) Agitated behaviour in the elderly: a conceptual review. Journal of American Geriatrics Society 34: 711-21. (Pubitemid 16028163)
15. Cummings JL, Mega M, Gray K, et al (1994) The neuropsychiatric inventory: comprehensive assessment of psychopathology in dementia. Neurology 44: 2308-14. (Pubitemid 24382728)
16. Derousene C, Rapin J, Lacomblez L, et al (2004) Memory complaints in 200 subjects meeting the diagnostic criteria for age-associated memory impairment: psychoaffective and cognitive correlates. Psychology and Neuropsychiatry 2: 67-74.
17. Evans S (2004) A survey of provision of psychological treatments to older adults in the NHS. Psychiatric Bulletin 28: 411-4.
18. Foy A, O'Connell D, Henry D, et al (1997) Benzodiazepine use as a cause of cognitive impairment in elderly hospital inpatients. JAMA 278: 27-31.
19. Gallacher J, Bayer A, Fish M, et al (2009) Does anxiety affect risk of dementia? Findings from Caerphilly prospective study. Psychosomatic Medicine 71: 659-66.
20. Gambi F, De Berardis D, Campanella D, et al (2005) Mirtazapine treatment of generalised anxiety disorder: a fixed dose, open-labelled study. Journal of Psychopharmacology 19: 483-7. (Pubitemid 41392302)
21. Gauthier S, Feldman H, Hecker J, et al (2002) Efficacy of donepezil on behavioural symptoms in patients with moderate to severe Alzheimer's disease. International Psychogeriatrics 14: 389-404. (Pubitemid 36331605)
22. Gorenstein E, Papp L (2007) Cognitive-behavioural therapy for anxiety in the elderly. Current Psychiatry Reports 9: 20-5.
23. Hancock GA, Woods B, Challis D, et al (2006) The needs of older people with dementia in residential care. International Journal of Geriatric Psychiatry 21: 43-9. (Pubitemid 43141495)
24. Katz IR, Reynolds CF, Alexopoulos GS, et al (2002) Venlafaxine ER as a treatment for generalised anxiety disorder in older adults: pooled analysis of five randomised placebo controlled trials. Journal of American Geriatric Society 50: 18-25. (Pubitemid 34053018)
25. Kinrys G, Wygant L (2005) Anticonvulsants in anxiety disorders. Current Psychiatry Reports 7: 258-67. (Pubitemid 41309528)
26. LaBarge E (1993) A preliminary scale to measure the degree of worry among mildly demented Alzheimer disease patients. Physical & Occupational Therapy in Geriatrics 11: 43-57.
27. Martinón-Torres G, Fioravanti M, Grimley Evans J (2004) Trazodone for agitation in dementia. Cochrane Database of Systematic Reviews issue 4: CD004990.
28. McIntyre A, Gendron A, McIntyre A (2006) Quetiapine adjunct to selective serotonin reuptake inhibitors or venlafaxine in patients with major depression, comorbid anxiety, and residual depressive symptoms: a randomized, placebo-controlled pilot study. Depression and Anxiety 24: 487-94.
29. Mendez MF, McMurtray A, Chen AK, et al (2006) Functional neuroimaging and presenting psychiatric features in frontotemporal dementia. Journal of Neurology, Neurosurgery and Psychiatry 77: 4-7. (Pubitemid 43022681)
30. Mintzer JE, Brawman-Mintzer O (1996) Agitation as a possible expression of generalised anxiety disorder in demented elderly patients: toward a treatment approach. Journal of Clinical Psychiatry 57 (suppl 7): 55-63. (Pubitemid 26269065)
31. Mohlman J, Gorenstein EE, Kleber M, et al (2003) Standard and enhanced cognitive behaviour therapy for late-life generalised anxiety disorder: two pilot investigations. American Journal of Geriatric Psychiatry 11: 24-32. (Pubitemid 36091340)
32. Montgomery S, Chatamra K, Pauer L, et al (2008) Efficacy and safety of pregabalin in elderly people with generalised anxiety disorder. British Journal of Psychiatry 193: 389-4.
33. Morinigo A, Blanco M, Labrador J, et al (2005) Risperidone for resistant anxiety in elderly patients. American Journal of Geriatric Psychiatry 13: 81-2. (Pubitemid 41031120)
34. Mynors-Wallis L (2001) Problem-solving treatment in general psychiatric practice. Advances in Psychiatric Treatment 7: 417-25.
35. National Collaborating Centre for Mental Health (2006) Dementia: Supporting People with Dementia and their Carers in Health and Social Care (NICE Clinical Guideline 42). National Institute for Health and Clinical Excellence.
36. National Collaborating Centre for Mental Health (2009) Depression: The Treatment and Management of Depression in Adults (NICE Clinical Guideline 90). National Institute for Health and Clinical Excellence.
37. National Collaborating Centre for Mental Health, National Collaborating Centre for Primary Care (2011) Generalised Anxiety Disorder and Panic Disorder (with or without Agoraphobia) in Adults: Management in Primary, Secondary and Community Care (NICE Clinical Guideline 113). National Institute for Health and Clinical Excellence.
38. Neal M, Barton Wright P (2003) Validation therapy for dementia. Cochrane Database of Systematic Reviews issue 3: CD001394.
39. Neutal CI, Hirdes JP, Maxwell CJ, et al (1996) New evidence on benzodiazepine use and falls: the time factor. Age and Ageing 24: 273-8. (Pubitemid 26245275)
40. Nordhus IH, Pallesen S (2003) Psychological treatment of late-life anxiety: an empirical review. Journal of Consulting and Clinical Psychology 71: 643-51. (Pubitemid 36897396)
41. Rabins PV, Blacker D, Rovner BW, et al (2007) American Psychiatric Association practice guideline for the treatment of patients with Alzheimer's disease and other dementias. Second edition. American Journal of Psychiatry 164 (suppl 12): 5-56.
42. Rozzini L, Chilovi BV, Peli M, et al (2009) Anxiety symptoms in mild cognitive impairment. International Journal of Geriatric Psychiatry 24: 300-5.
43. Scottish Intercollegiate Guidelines Network (2006) Management of Patients with Dementia: A National Clinical Guideline (no. 86). SIGN.
44. Seignourel PJ, Kunik ME, Snow L, et al (2008) Anxiety in dementia: a critical review. Clinical Psychological Review 28: 1071-82.
45. Shah A, Wadoo O, Latoo J (2010) Psychological distress in carers of people with mental disorders. British Journal of Medical Practitioners 3: a327.
46. Shankar KK, Walker M, Frost D (1999) The development of a valid and reliable scale for rating anxiety in people with dementia (RAID). Aging & Mental Health 3: 39-49. (Pubitemid 29182197)
47. Sink KC, Holden KF, Yaffe K (2005) Pharmacological treatment of neuropsychiatric symptoms of dementia: a review of the evidence. JAMA 293: 596-608. (Pubitemid 40171242)
48. Spector A, Davies S, Woods B, et al (2000) Reality orientation for dementia: a systematic review of the evidence of effectiveness for randomised controlled trials. Gerontologist 40: 206-12. (Pubitemid 30266288)
49. Spector A, Thorgrimsen L, Woods B, et al (2003) Efficacy of an evidence-based cognitive stimulation therapy programme for people with dementia: randomised controlled trial. British Journal of Psychiatry 183: 248-54. (Pubitemid 37070181)
50. Starkstein SE, Jorge R, Petracca G, et al (2007) The construct of generalised anxiety disorder in Alzheimer disease. American Journal of Geriatric Psychiatry 15: 42-9. (Pubitemid 46106089)
51. Thompson S, Herrmann N, Rapoport MJ, et al (2007) Efficacy and safety of antidepressants for treatment of depression in Alzheimer's disease: a meta analysis. Canadian Journal of Psychiatry 52: 248-55. (Pubitemid 46743472)
52. Tsuang MT (1978) Genetic counseling for psychiatric patients and their families. American Journal of Psychiatry 135: 1465-75.
53. Twelftree H, Qazi A (2006) Relationship between anxiety and agitation in dementia. Aging & Mental Health 10: 362-7. (Pubitemid 43977370)
54. Wagner AK, Zhang F, Soumerai SB, et al (2004) Benzodiazepine use and hip fractures in the elderly: who is at greatest risk? [Article in German] Archives of Internal Medicine 164: 1567-72. (Pubitemid 38970480)
55. Wetterling T, Backhaus J, Junghanns K (2002) Addiction in the elderly -an underestimated diagnosis in clinical practice? Nervenarzt 73: 861-6. (Pubitemid 36062322)
56. Wilson SJ, Nutt DJ, Alford C, et al (2010) British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders. Journal of Psychopharmacology (BAP Consensus Guidelines Special Issue): 1-25.
57. Wing JK, Babor T, Brugha T, et al (1990) SCAN: Schedules for Clinical Assessment in Neuropsychiatry. Archives of General Psychiatry 47: 589-93. (Pubitemid 20189971)
58. Woods B, Spector AE, Jones CA, et al (2005) Reminiscence therapy for dementia. Cochrane Database of Systematic Reviews issue 2: CD001120.