Protein recognition of hetero-/homoleptic ruthenium(II) tris(bipyridine)s for α-chymotrypsin and cytochrome c

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 6, 2012, Pages 2354-2358

  Yamaguchi, Yoshinobu ^a   Kato, Nobuo ^a   Azuma, Hideki ^b   Nagasaki, Takeshi ^b   Ohkanda, Junko ^a  

^a OSAKA UNIVERSITY   (Japan)

^b Osaka Prefecture University   (Japan)

Author keywords

Chymotrypsin; Cytochrome c; Hetero homoleptic ruthenium(II) tris(bipyridine)s; Inhibition activity; Protein surface recognition

Indexed keywords

CHYMOTRYPSIN A; CYTOCHROME C; METAL COMPLEX; PROTEIN INHIBITOR; PYRIDINE DERIVATIVE; RUTHENIUM; RUTHENIUM TRIS(BIPYRIDINE)DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CELL PERMEABILIZATION; DRUG PENETRATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; PROTEIN TARGETING;

2,2'-DIPYRIDYL; APOPTOSIS; ASCORBIC ACID; BINDING SITES; CELL LINE, TUMOR; CELL MEMBRANE PERMEABILITY; CHYMOTRYPSIN; COORDINATION COMPLEXES; CYTOCHROMES C; HUMANS; KINETICS; MODELS, MOLECULAR; OXIDATION-REDUCTION; POTENTIOMETRY; PROTEIN BINDING; RUTHENIUM; THERMODYNAMICS;

EID: 84857873498     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.12.087     Document Type: Article

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