Editorial: NKT get the 'flu: NKT cells as (mostly) good guys in influenza; monocytic cells as double agents

Journal of Leukocyte Biology

Volumn 91, Issue 3, 2012, Pages 349-352

  Exley, Mark A ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD1D ANTIGEN; INFLUENZA VACCINE;

B LYMPHOCYTE; EDITORIAL; EOSINOPHIL; HUMAN; IMMUNOPATHOLOGY; IMMUNOSURVEILLANCE; INFLUENZA; MONOCYTE; NATURAL KILLER T CELL; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

ANIMALS; HUMANS; INFLAMMATION; INFLUENZA A VIRUS; LUNG; MONOCYTES; NATURAL KILLER T-CELLS; ORTHOMYXOVIRIDAE INFECTIONS;

EID: 84857855442     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0911468     Document Type: Editorial

References (19)

1. Kok, W. L., Denney, L., Benam, K., Cole, S., Clelland, C., McMichael, A., Ho, L. P. (2012) Pivotal Advance: invariant NKT cells reduce accumulation of inflammatory monocytes in the lungs and decrease immune-pathology during lethal influenza A virus infection. J. Leukoc. Biol. 91, 357-368.
2. Tessmer, M. S., Fatima, A., Paget, C., Trottein, F., Brossay, L. (2009) NKT cell immune responses to viral infection. Expert Opin. Ther. Targets 13, 153-162.
3. Berzins, S. P., Smyth, M. J., Baxter, A. G. (2011) Presumed guilty: natural killer T cell defects and human disease. Nat. Rev. Immunol. 11, 131-142.
4. Sakai, S., Mantani, N., Kogure, T., Ochiai, H., Shimada, Y., Terasawa, K. (2002) Gene expression of cell surface antigens in the early phase of murine influenza pneumonia determined by a cDNA expression array technique. Med. Inflamm. 11, 359-361.
5. Benton, K. A., Misplon, J. A., Lo, C. Y., Brutkiewicz, R. R., Prasad, S. A., Epstein, S. L. (2001) Heterosubtypic immunity to influenza A virus in mice lacking IgA, all Ig, NKT cells, or γ δ T cells. J. Immunol. 166, 7437-7445.
6. Galli, G., Pittoni, P., Tonti, E., Malzone, C., Uematsu, Y., Tortoli, M., Maione, D., Volpini, G., Finco, O., Nuti, S., Tavarini, S., Dellabona, P., Rappuoli, R., Casorati, G., Abrignani, S. (2007) Invariant NKT cells sustain specific B cell responses and memory. Proc. Natl. Acad. Sci. USA 104, 3984-3989.
7. Youn, H. J., Ko, S. Y., Lee, K. A., Ko, H. J., Lee, Y. S., Fujihashi, K., Boyaka, P. N., Kim, S. H., Horimoto, T., Kweon, M. N., Kang, C. Y. (2007) A single intranasal immunization with inactivated influenza virus and α-galactosylceramide induces long-term protective immunity without redirecting antigen to the central nervous system. Vaccine 25, 5189-5198.
8. Kamijuku, H., Nagata, Y., Jiang, X., Ichinohe, T., Tashiro, T., Mori, K., Taniguchi, M., Hase, K., Ohno, H., Shimaoka, T., Yonehara, S., Odagiri, T., Tashiro, M., Sata, T., Hasegawa, H., Seino, K. I. (2008) Mechanism of NKT cell activation by intranasal coadministration of α-galactosylceramide, which can induce cross-protection against influenza viruses. Mucosal Immunol. 1, 208-218.
9. Guillonneau, C., Mintern, J. D., Hubert, F. X., Hurt, A. C., Besra, G. S., Porcelli, S., Barr, I. G., Doherty, P. C., Godfrey, D. I., Turner, S. J. (2009) Combined NKT cell activation and influenza virus vaccination boosts memory CTL generation and protective immunity. Proc. Natl. Acad. Sci. USA 106, 3330-3335.
10. Kopecky-Bromberg, S. A., Fraser, K. A., Pica, N., Carnero, E., Moran, T. M., Franck, R. W., Tsuji, M., Palese, P. (2009) α-C-Galactosylceramide as an adjuvant for a live attenuated influenza virus vaccine. Vaccine 27, 3766-3774.
11. Li, K., Luo, J., Wang, C., He, H. (2011) α-Galactosylceramide potently augments M2e-induced protective immunity against highly pathogenic H5N1 avian influenza virus infection in mice. Vaccine 29, 7711-7717.
12. Johnson, T. R., Hong, S., Van Kaer, L., Koezuka, Y., Graham, B. S. (2002) NK T cells contribute to expansion of CD8(+) T cells and amplification of antiviral immune responses to respiratory syncytial virus. J. Virol. 76, 4294-4303.
13. Kim, E. Y., Battaile, J. T., Patel, A. C., You, Y., Agapov, E., Grayson, M. H., Benoit, L. A., Byers, D. E., Alevy, Y., Tucker, J., Swanson, S., Tidwell, R., Tyner, J. W., Morton, J. D., Castro, M., Polineni, D., Patterson, G. A., Schwendener, R. A., Allard, J. D., Peltz, G., Holtzman, M. J. (2008) Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease. Nat. Med. 14, 633-640.
14. Paget, C., Ivanov, S., Fontaine, J., Blanc, F., Pichavant, M., Renneson, J., Bialecki, E., Pothlichet, J., Vendeville, C., Barba-Speath, G., Huerre, M. R., Faveeuw, C., Si-Tahar, M., Trottein, F. (2011) Potential role of invariant NKT cells in the control of pulmonary inflammation and CD8+ T cell response during acute influenza A virus H3N2 pneumonia. J. Immunol. 186, 5590-5602.
15. De Santo, C., Salio, M., Masri, S. H., Lee, L. Y., Dong, T., Speak, A. O., Porubsky, S., Booth, S., Veerapen, N., Besra, G. S., Gröne, H. J., Platt, F. M., Zambon, M., Cerundolo, V. (2008) Invariant NKT cells reduce the immunosuppressive activity of influenza A virusinduced myeloid-derived suppressor cells in mice and humans. J. Clin. Invest. 118, 4036-4048.
16. Ho, L. P., Denney, L., Luhn, K., Teoh, D., Clelland, C., McMichael, A. J. (2008) Activation of invariant NKT cells enhances the innate immune response and improves the disease course in influenza A virus infection. Eur. J. Immunol. 38, 1913-1922.
17. Schneiders, F. L., Scheper, R. J., von Blomberg, B. M., Woltman, A. M., Janssen, H. L., van den Eertwegh, A. J., Verheul, H. M., de Gruijl, T. D., van der Vliet, H. J. (2011) Clinical experience with α-galactosylceramide (KRN7000) in patients with advanced cancer and chronic hepatitis B/C infection. Clin. Immunol. 140, 130-141.
18. Exley, M., Bigley, N., Cheng, O., Tahir, S., Smiley, S., Carter, Q., Stills, H., Grusby, M., Koezuka, Y., Taniguchi, M. and Balk, S. (2001) CD1d-reactive T cell activation leads to amelioration of disease caused by diabetogenic encephalomyocarditis virus. J. Leukoc. Biol. 69, 713-718.
19. Aldridge Jr., J. R., Moseley, C. E., Boltz, D. A., Negovetich, N. J., Reynolds, C., Franks, J., Brown, S. A., Doherty, P. C., Webster, R. G., Thomas, P. G. (2009) TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection. Proc. Natl. Acad. Sci. USA 106, 5306-5311.