Biochemical characterization of novel lignans isolated from the wood of Taxus yunnanensis as effective stimulators for glycogen synthase kinase-3β and the phosphorylation of basic brain proteins by the kinase in vitro

Biological and Pharmaceutical Bulletin

Volumn 35, Issue 3, 2012, Pages 385-393

  Ohtsuki, Kenzo ^a   Miyai, Sayaka ^a   Yamaguchi, Akira ^a   Morikawa, Kouhei ^a   Okano, Tetsuroh ^a  

^a KITASATO UNIVERSITY   (Japan)

Author keywords

Glycogen synthase kinase 3 ; Protein phosphorylation; Stimulatory effect; Taxus lignan

Indexed keywords

4' HYDROXY 6,3' DIMETHOXYISOFLAVAN 4 OL; 7 HYDROXYTAXIRESINOL; BRAIN PROTEIN; COLLAPSIN RESPONSE MEDIATOR PROTEIN 2; EPIGALLOCATECHIN GALLATE; GLYCOGEN SYNTHASE KINASE 3BETA; LIGNAN; MYELIN BASIC PROTEIN; PLANT EXTRACT; TANEGOOL; TAU PROTEIN; TAXUS YUNNANENSIS EXTRACT; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BIOCHEMISTRY; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; IN VITRO STUDY; NONHUMAN; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; RAT; TAXUS WALLICHIANA VAR. WALLICHIANA;

ANIMALS; BRAIN; CATECHIN; CATTLE; GLYCOGEN SYNTHASE KINASE 3; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGNANS; MYELIN BASIC PROTEINS; NERVE TISSUE PROTEINS; PHOSPHORYLATION; PLANT EXTRACTS; RATS; RECOMBINANT PROTEINS; TAU PROTEINS; TAXUS; WOOD;

EID: 84857843682     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.35.385     Document Type: Article

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