Monitoring of gluten-free diet compliance in celiac patients by assessment of gliadin 33-mer equivalent epitopes in feces

American Journal of Clinical Nutrition

Volumn 95, Issue 3, 2012, Pages 670-677

  Comino, Isabel ^a   Real, Ana ^a   Vivas, Santiago ^b   Síglez, Miguel Ángel ^c   Caminero, Alberto ^d   Nistal, Esther ^d   Casqueiro, Javier ^d   Rodríguez Herrera, Alfonso ^e   Cebolla, Ángel ^c   Sousa, Carolina ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

^b HOSPITAL UNIVERSITARIO DE LEÓN   (Spain)

^c Biomedal SL   (Spain)

^d UNIVERSITY OF LEÓN   (Spain)

^e Instituto Hispalense de Pediatria   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CHYMOTRYPSIN; EPITOPE; GLIADIN; GLIADIN ANTIBODY; GLUTEN; MONOCLONAL ANTIBODY; PEPSIN A; TRYPSIN;

ARTICLE; CELIAC DISEASE; CHILD; CLINICAL ASSESSMENT; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FECES; FEMALE; FOOD INTAKE; GLUTEN FREE DIET; HUMAN; IMMUNOAFFINITY CHROMATOGRAPHY; IMMUNOTOXICITY; IN VITRO STUDY; IN VIVO STUDY; INFANT; MAJOR CLINICAL STUDY; MALE; PATIENT COMPLIANCE; PRESCHOOL CHILD; SCHOOL CHILD;

ADOLESCENT; ADULT; CELIAC DISEASE; CHILD; CHILD, PRESCHOOL; DIET, GLUTEN-FREE; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; FECES; FEMALE; GLIADIN; HUMANS; IMMUNOCHROMATOGRAPHY; INTERVIEWS AS TOPIC; MALE; PATIENT COMPLIANCE; PHENYLPROPANOLAMINE; YOUNG ADULT;

EID: 84857803374     PISSN: 00029165     EISSN: 19383207     Source Type: Journal    
DOI: 10.3945/ajcn.111.026708     Document Type: Article

References (23)

1. Fasano A. Surprises from celiac disease. Sci Am 2009;301:54-61.
2. Ganapathy V, Gupta N, Martindale RG. Physiology of the gastrointestinal tract. 4th ed. New York, NY: Johnson LR, 2006.
3. Shan L, Molberg Ø, Parrot I, Hausch F, Filiz F, Gray GM, Sollid LM, Khosla C. Structural basis for gluten intolerance in celiac sprue. Science 2002;297:2275-9.
4. Bethune MT, Crespo-Bosque M, Bergseng E, Mazumdar K, Doyle L, Sestak K, Sollid LM, Khosla C. Noninflammatory gluten peptide analogs as biomarkers for celiac sprue. Chem Biol 2009;16:868-81.
5. Tye-Din JA, Stewart JA, Dromey JA, Beissbarth T, van Heel DA, Tatham A, Henderson K, Mannering SI, Gianfrani C, Jewell DP, et al. Comprehensive, quantitative mapping of T cell epitopes in gluten in celiac disease. Sci Transl Med 2010;2:41ra51.
6. Silvester JA, Rashid M. Long-term follow-up of individuals with celiac disease: an evaluation of current practice guidelines. Can J Gastroenterol 2007;21:557-64. (Pubitemid 350011438)
7. Hadithi M, Peña AS. Current methods to diagnose the unresponsive and complicated forms of coeliac disease. Eur J Intern Med 2010;21:247-53.
8. Walker MM, Murray JA. An update in the diagnosis of disease. Histopathology 2011;59:166-79.
9. Fernández-Calle P, Codoceo R, Polanco I, Gómez-Cerezo J, Orsi M, Tenias JM. Is an intestinal permeability test a valid marker for slight dietary transgressions in adolescents with coeliac disease? Gut 1993; 34:774-7. (Pubitemid 23185102)
10. Tack GJ, Verbeek WH, Schreurs MW, Mulder CJ. The spectrum of celiac disease: epidemiology, clinical aspects and treatment. Nat Rev Gastroenterol Hepatol 2010;7:204-13.
11. Selimoǧlu MA, Karabiber H. Celiac disease: prevention and treatment. J Clin Gastroenterol 2010;44:4-8.
12. Duerksen DR, Wilhelm-Boyles C, Parry DM. Intestinal permeability in long-term follow-up of patients with celiac disease on a gluten-free diet. Dig Dis Sci 2005;50:785-90. (Pubitemid 40558478)
13. Ertekin V, Selimoǧlu MD, Turgut A, Bakan N. Fecal calprotectin concentration in celiac disease. J Clin Gastroenterol 2010;44:544-6.
14. Morón B, Cebolla A, Manyani H, Alvarez-Maqueda M, Megías M, Thomas M C, López MC, Sousa C. Sensitive detection of cereal fractions that are toxic to celiac disease patients by using monoclonal antibodies to a main immunogenic wheat peptide. Am J Clin Nutr 2008;87:405-14. (Pubitemid 351226078)
15. Morón B, Bethune M, Comino I, Manyani H, Ferragud M, López MC, Cebolla A, Khosla C, Sousa C. Toward the assessment of food toxicity for celiac patients: Characterization of monoclonal antibodies to a main immunogenic gluten peptide. PLoS ONE 2008;3:e2294.
16. Marsh MN, Crowe PT. Morphology of the mucosal lesion in gluten sensitivity. Baillieres Clin Gastroenterol 1995;9:273-93.
17. Comino I, Real A, de Lorenzo L, Cornell H, López-Casado MÁ, Barro F, Lorite P, Torres MI, Cebolla A, Sousa C. Diversity in oat potential immunogenicity: basis for the selection of oat varieties with no toxicity in celiac disease. Gut 2011;60:915-22.
18. Sousa C, Johansson C, Charon C, Manyani H, Sautter C, Kondorosi A, Crespi M. Translational and structural requirements of the early nodulin gene enod40, a short-open reading frame-containing RNA, for elicitation of a cell-specific growth response in the alfalfa root cortex. Mol Cell Biol 2001;21:354-66.
19. Catassi C, Fabiani E, Iacono G, D'Agate C, Francavilla R, Biagi F, Volta U, Accomando S, Picarelli A, De Vitis I, et al. A prospective, doubleblind, placebo-controlled trial to establish a safe gluten threshold for patients with celiac disease. Am J Clin Nutr 2007;85:160-6. (Pubitemid 46067630)
20. Sonnenburg JL, Fischbach MA. Community health care: therapeutic opportunities in the human microbiome. Sci Transl Med 2011;3: 78ps12.
21. Ehren J, Morón B, Martin E, Bethune MT, Gray GM, Khosla C. A food-grade enzyme preparation with modest gluten detoxification properties. PLoS ONE 2009;4:e6313.
22. Leffler DA, Dennis M, Hyett B, Kelly E, Schuppan D, Kelly CP. Etiologies and predictors of diagnosis in nonresponsive celiac disease. Clin Gastroenterol Hepatol 2007;5:445-50. (Pubitemid 46575362)
23. Shan L, Qiao SW, Arentz-Hansen H, Molberg Ø, Gray GM, Sollid LM, Khosla C. Identification and analysis of multivalent proteolytically resistant peptides from gluten: implications for celiac sprue. J Proteome Res 2005;4:1732-41. (Pubitemid 41464801)