Hepatocellular carcinoma in non-cirrhotic liver without evidence of iron overload in a patient with primary hemochromatosis. Review

Journal of Gastrointestinal Cancer

Volumn 43, Issue 1, 2012, Pages 36-39

  Singh, Parminder ^a   Kaur, Harneet ^a   Lerner, Robert G ^a   Patel, Roshan ^a   Rafiyath, Shamudheen M ^a   Singh Lamba, Gurpreet ^a  

^a WESTCHESTER MEDICAL CENTER   (United States)

Author keywords

Hemochromatosis; Hepatocellular carcinoma; Non cirrhotic liver; Radiation exposure

Indexed keywords

LIVER ENZYME; PARACETAMOL;

ABDOMINAL DISCOMFORT; AGED; ATOMIC BOMB SURVIVOR; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; CONFERENCE PAPER; FOLLOW UP; GOUT; HEMOCHROMATOSIS; HEPATOMEGALY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYPERTENSION; HYPOTHYROIDISM; IRON OVERLOAD; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER TUMOR; MALE; MEDLINE; NUCLEAR MAGNETIC RESONANCE IMAGING; PHLEBOTOMY; PRIORITY JOURNAL; RADIATION EXPOSURE; ULTRASOUND; UPPER ABDOMINAL PAIN; WEIGHT REDUCTION;

AGED; CARCINOMA, HEPATOCELLULAR; HEMOCHROMATOSIS; HUMANS; LIVER CIRRHOSIS; LIVER NEOPLASMS; MALE; NUCLEAR WARFARE;

EID: 84857801482     PISSN: 19416628     EISSN: 19416636     Source Type: Journal    
DOI: 10.1007/s12029-010-9205-5     Document Type: Conference Paper

References (15)

1. C Niederau R Fischer A Sonnenberg W Stremmel HJ Trampisch G Strohmeyer 1985 Survival and causes of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis N Engl J Med 313 20 1256 62 4058506 10.1056/NEJM198511143132004 1:STN:280:DyaL28%2FktVansw%3D%3D (Pubitemid 16217048)
2. JB Cologne S Tokuoka GW Beebe T Fukuhara K Mabuchi 1999 Effects of radiation on incidence of primary liver cancer among atomic bomb survivors Radiat Res 152 4 364 73 10477913 10.2307/3580221 1:CAS:528:DyaK1MXmsVCmurc%3D (Pubitemid 29463614)
3. ES Gilbert NA Koshurnikova M Sokolnikov VF Khokhryakov S Miller DL Preston SA Romanov NS Shilnikova KG Suslova VV Vostrotin 2000 Liver cancers in Mayak workers Radiat Res 154 3 246 52 10956429 10.1667/0033-7587(2000)154[0246: LCIMW]2.0.CO;2 1:CAS:528:DC%2BD3cXms1GhsLg%3D Radiation Epidemiology Branch, National Cancer Institute, Bethesda, Maryland 20852, USA
4. MM Weil JS Bedford H Bielefeldt-Ohmann FA Ray PC Genik EJ Ehrhart CM Fallgren F Hailu CL Battaglia B Charles MA Callan RL Ullrich 2009 Incidence of acute myeloid leukemia and hepatocellular carcinoma in mice irradiated with 1 GeV/nucleon (56)Fe ions Radiat Res 172 2 213 9 19630525 10.1667/RR1648.1 1:CAS:528:DC%2BD1MXps1eks78%3D
5. Y Yamamoto N Usuda T Takatsuji Y Kuwahara M Fukumoto 2009 Long incubation period for the induction of cancer by thorotrast is attributed to the uneven irradiation of liver cells at the microscopic level Radiat Res 171 4 494 503 19397450 10.1667/RR1492.1 1:CAS:528:DC%2BD1MXjslSltbg%3D
6. F Trevisani PE D'Intino P Caraceni M Pizzo GF Stefanini A Mazziotti GL Grazi G Gozzetti G Gasbarrini M Bernardi 1995 Etiologic factors and clinical presentation of hepatocellular carcinoma. Differences between cirrhotic and noncirrhotic Italian patients Cancer 75 9 2220 32 7536121 10.1002/1097- 0142(19950501)75:9<2220::AID-CNCR2820750906>3.0.CO;2-4 1:STN:280:DyaK2M3isl2qug%3D%3D
7. TK Shires 1982 Iron-induced DNA damage and synthesis in isolated rat liver nuclei Biochem J 205 2 321 9 7138506 1:CAS:528:DyaL38XlvFCisro%3D (Pubitemid 13226503)
8. BR Bacon RS Britton 1990 The pathology of hepatic iron overload: a free radical-mediated process? Hepatology 11 1 127 37 2153094 10.1002/hep.1840110122 1:CAS:528:DyaK3cXitlejtbg%3D Review (Pubitemid 20075113)
9. GM Williams RS Yamamoto 1972 Absence of stainable iron from preneoplastic and neoplastic lesions in rat liver with 8-hydroxyquinoline-induced siderosis J Natl Cancer Inst 49 3 685 92 4647491 1:CAS:528:DyaE38Xls1WksLo%3D
10. RS Blumberg S Chopra R Ibrahim J Crawford FA Farraye JB Zeldis MD Berman 1988 Primary hepatocellular carcinoma in idiopathic hemochromatosis after reversal of cirrhosis Gastroenterology 95 5 1399 402 2844622 1:STN:280:DyaL1M%2Fgs1WnsQ%3D%3D
11. IW Fellows M Stewart WJ Jeffcoate PG Smith PJ Toghill 1988 Hepatocellular carcinoma in primary haemochromatosis in the absence of cirrhosis Gut 29 11 1603 6 2850272 10.1136/gut.29.11.1603 1:STN:280:DyaL1M%2Fpt1Whsg%3D%3D
12. NP Thompson G Stansby M Jarmulowicz KE Hobbs N McIntyre 1995 Hepatocellular carcinoma arising in non-cirrhotic haemochromatosis HPB Surg 8 3 163 6 7547618 10.1155/1995/46986 1:STN:280:DyaK28%2FivVOmtw%3D%3D
13. J Goh G Callagy G McEntee JC O'Keane A Bomford J Crowe 1999 Hepatocellular carcinoma arising in the absence of cirrhosis in genetic haemochromatosis: three case reports and review of literature Eur J Gastroenterol Hepatol 11 8 915 9 10514128 10.1097/00042737-199908000-00019 1:STN:280:DyaK1Mvkt1eisQ%3D%3D (Pubitemid 29389528)
14. A Singal ML Volk A Waljee R Salgia P Higgins MA Rogers JA Marrero 2009 Meta-analysis: surveillance with ultrasound for early-stage hepatocellular carcinoma in patients with cirrhosis Aliment Pharmacol Ther 30 1 37 47 19392863 10.1111/j.1365-2036.2009.04014.x 1:STN:280:DC%2BD1MvltlyqtQ%3D%3D
15. V Grando-Lemaire C Guettier S Chevret M Beaugrand JC Trinchet 1999 Hepatocellular carcinoma without cirrhosis in the West: epidemiological factors and histopathology of the non-tumorous liver J Hepatol 31 3 508 13 10488711 10.1016/S0168-8278(99)80044-0 1:STN:280:DyaK1Mvhs1yitg%3D%3D (Pubitemid 29408735)