Molecular profiles of IgE to Phleum pratense in children with grass pollen allergy: Implications for specific immunotherapy

Journal of Allergy and Clinical Immunology

Volumn 129, Issue 3, 2012, Pages

  Tripodi, Salvatore ^a   Frediani, Tullio ^b   Lucarelli, Sandra ^b   MacR, Francesco ^b   Pingitore, Giuseppe ^c   Di Rienzo Businco, Andrea ^a   Dondi, Arianna ^d   Pansa, Paola ^b   Ragusa, Giovanni ^b   Asero, Riccardo ^e   Faggian, Diego ^f   Plebani, Mario ^f   Matricardi, Paolo Maria ^g  

^a SANDRO PERTINI HOSPITAL   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c GB Grassi Hospital   (Italy)

^d UNIVERSITY OF BOLOGNA   (Italy)

^e Clinica San Carlo   (Italy)

^f UNIVERSITY OF PADOVA   (Italy)

^g CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Allergenic molecules; atopy; children; classification; combinatorial analysis; component resolved diagnosis; component resolved therapy; epidemiology; grass pollen; hay fever; molecular profiles; Phleum pratense; specific IgE

Indexed keywords

GRASS POLLEN EXTRACT; IMMUNOGLOBULIN E;

ADOLESCENT; ADULT; ARTICLE; CHILD; CHILDHOOD DISEASE; CROSS-SECTIONAL STUDY; FEMALE; HUMAN; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOTHERAPY; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; PHLEUM PRATENSE; POLLEN ALLERGY; PRESCHOOL CHILD; PRICK TEST; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUESTIONNAIRE; SCHOOL CHILD; SENSITIZATION;

EID: 84857801459     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2011.10.045     Document Type: Article

References (31)

1. P. Burney, E. Malmberg, S. Chinn, D. Jarvis, C. Luczynska, and E. Lai The distribution of total and specific serum IgE in the European Community Respiratory Health Survey J Allergy Clin Immunol 99 1997 314 322 (Pubitemid 27123910)
2. V. Bauchau, and S.R. Durham Prevalence and rate of diagnosis of allergic rhinitis in Europe Eur Respir J 24 2004 758 764 (Pubitemid 39504428)
3. G.W. Canonica, P.B. Poulsen, and U. Vestenbæk Cost-effectiveness of GRAZAX® for prevention of grass pollen induced rhinoconjunctivitis in Southern Europe Respir Med 101 2007 1885 1894 (Pubitemid 47163544)
4. R. Natan The burden of allergic rhinitis Allergy Asthma Proc 28 2007 3 9
5. J. Bousquet, H.J. Schünemann, T. Zuberbier, C. Bachert, C.E. Baena-Cagnani, and P.J. Bousquet Development and implementation of guidelines in allergic rhinitis: an ARIA-GA2LEN paper Allergy 65 2010 1212 1221
6. S.R. Durham, S.M. Walker, E.M. Varga, M.R. Jacobson, F. O'Brien, and W. Noble Long-term clinical efficacy of grass-pollen immunotherapy N Engl J Med 341 1999 468 475 (Pubitemid 29372886)
7. C. Möller, S. Dreborg, H.A. Ferdousi, S. Halken, A. Høst, and L. Jacobsen Pollen immunotherapy reduces the development of asthma in children with seasonal rhinoconjunctivitis (the PAT-study) J Allergy Clin Immunol 109 2002 251 256 (Pubitemid 34158289)
8. J.N. Larsen, C.G. Houghton, M.L. Vega, and H. Løwenstein Manufacturing and standardizing allergen extracts in Europe Clin Allergy Immunol 21 2008 283 301
9. R. Rossi, G. Monasterolo, and G. Passalacqua The biological potency of different extracts for sublingual immunotherapy assessed by skin prick tests Eur Ann Allergy Clin Immunol 42 2010 112 114
10. H. Schmidt, C. Gelhaus, M. Nebendahl, O. Janssen, and A. Petersen Characterization of Phleum pratense pollen extracts by 2-D DIGE and allergen immunoreactivity Proteomics 10 2010 4352 4362
11. R. Valenta, J. Lidholm, V. Niederberger, B. Hayek, D. Kraft, and H. Grönlund The recombinant allergen-based concept of component-resolved diagnostics and immunotherapy (CRD and CRIT) Clin Exp Allergy 29 1999 896 904 (Pubitemid 29317799)
12. R. Valenta The future of antigen-specific immunotherapy of allergy Nat Rev Immunol 2 2002 446 453 (Pubitemid 37328752)
13. K. Andersson, and J. Lidholm Characteristics and immunobiology of grass pollen allergens Int Arch Allergy Immunol 130 2003 87 107 (Pubitemid 36351233)
14. C. Suphioglu What are the most important allergens in grass pollen that are linked to human allergic disease? Clin Exp Allergy 30 2000 1335 1341
15. M. Jutel, L. Jaeger, R. Suck, H. Meyer, H. Fiebig, and O. Cromwell Allergen-specific immunotherapy with recombinant grass pollen allergens J Allergy Clin Immunol 116 2005 608 613 (Pubitemid 41267135)
16. R.E. Rossi, G. Monasterolo, and S. Monasterolo Measurement of IgE antibodies against purified grass-pollen allergens (Phl p 1, 2, 3, 4, 5, 6, 7, 11, and 12) in sera of patients allergic to grass pollen Allergy 56 2001 1180 1185 (Pubitemid 33086979)
17. A. Mari Skin test with a timothy grass (Phleum pratense) pollen extract vs. IgE to a timothy extract vs. IgE to rPhl p 1, rPhl p 2, nPhl p 4, rPhl p 5, rPhl p 6, rPhl p 7, rPhl p 11, and rPhl p 12: epidemiological and diagnostic data Clin Exp Allergy 33 2003 43 51 (Pubitemid 36114906)
18. E. Scala, C. Alessandri, M.L. Bernardi, R. Ferrara, P. Palazzo, and D. Pomponi Cross-sectional survey on immunoglobulin E reactivity in 23,077 subjects using an allergenic molecule-based microarray detection system Clin Exp Allergy 40 2010 911 921
19. A.E. Tozzi, L. Armenio, R. Bernardini, A. Boner, M. Calvani, and F. Cardinale Pediatric allergy and immunology in Italy Pediatr Allergy Immunol 22 2011 267 276
20. M.I. Asher, U. Keil, H.R. Anderson, R. Beasley, R. Beasley, and J. Crane International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods Eur Respir J 8 1995 483 491
21. E.D. Bateman, S.S. Hurd, P.J. Barnes, J. Bousquet, J.M. Drazen, and M. Fitzgerald Global strategy for asthma management and prevention: GINA executive summary Eur Respir J 31 2008 143 178
22. I. Jáuregui, I. Dávila, J. Sastre, J. Bartra, A. del Cuvillo, and M. Ferrer Validation of ARIA (Allergic Rhinitis and its Impact on Asthma) classification in a pediatric population: the PEDRIAL study Pediatr Allergy Immunol 22 2011 388 392
23. S. Dreborg The skin prick test in the diagnosis of atopic allergy J Am Acad Dermatol 21 1989 820 821 (Pubitemid 19247546)
24. B. Fahlbusch, W.D. Müller, O. Rudeschko, L. Jäger, O. Cromwell, and H. Fiebig Detection and quantification of group 4 allergens in grass pollen extracts using monoclonal antibodies Clin Exp Allergy 28 1998 799 807 (Pubitemid 28335557)
25. S. Kaul, L. Englert, S. May, and S. Vieths Regulatory aspects of specific immunotherapy in Europe Curr Opin Allergy Clin Immunol 10 2010 594 602
26. R. Moverare, L. Elfman, E. Vesterinen, T. Metso, and T. Haahtela Development of new IgE reactivities to allergenic components in pollen extracts during specific immunotherapy studied with immunoblotting and the Pharmacia CAP system Allergy 57 2002 423 430 (Pubitemid 34442156)
27. R. Asero Lack of de novo sensitization to tropomyosin in a group of mite-allergic patients treated by house dust mite-specific immunotherapy Int Arch Allergy Immunol 137 2005 62 65 (Pubitemid 40754723)
28. C. Suphiloglu What are the important allergens in grass pollen which are linked to human allergic disease? Clin Exp Allergy 30 2000 1335 1341
29. C. Metz-Favre, B. Linhart, M. Focke-Tejkl, A. Purohit, F. de Blay, and R. Valenta Skin test diagnosis of grass pollen allergy with a recombinant hybrid molecule J Allergy Clin Immunol 120 2007 315 321 (Pubitemid 47411527)
30. S. Dreborg The skin prick test in the diagnosis of atopic allergy J Am Acad Dermatol 21 1989 820 821 (Pubitemid 19247546)
31. S. Kaul, L. Englert, S. May, and S. Vieths Regulatory aspects of specific immunotherapy in Europe Curr Opin Allergy Clin Immunol 10 2010 594 602