How do thermophilic proteins resist aggregation?

Proteins: Structure, Function and Bioinformatics

Volumn 80, Issue 4, 2012, Pages 1003-1015

  Thangakani, Anthony Mary ^a   Kumar, Sandeep ^b   Velmurugan, Devadasan ^a   Gromiha, Maria Siluvay Michael ^c  

^a UNIVERSITY OF MADRAS   (India)

^b PFIZER INC   (United States)

^c INDIAN INSTITUTE OF TECHNOLOGY MADRAS   (India)

Author keywords

Aggregation; Biotherapeutics; Mesophiles; Proteins; Thermophiles

Indexed keywords

AMYLOID; ARGININE; ASPARAGINE; GLUTAMINE; HEXAPEPTIDE; LYSINE; MONOMER; PROLINE; PROTEIN; TETRAPEPTIDE; THERMOPHILIC PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; CROSS REACTION; HYDROPHOBICITY; MESOPHILE; MOLECULAR EVOLUTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DATABASE; PROTEIN MOTIF; STRUCTURAL HOMOLOGY; THERMOPHILE;

ALGORITHMS; AMINO ACID SEQUENCE; AMYLOID; BACILLUS; BACTERIAL PROTEINS; COMPUTATIONAL BIOLOGY; CONSERVED SEQUENCE; HEAT-SHOCK PROTEINS; HYDROGEN-ION CONCENTRATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN INTERACTION MAPPING; PROTEIN STABILITY; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, PROTEIN; SOLVENTS; THERMODYNAMICS;

EID: 84857793371     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.24002     Document Type: Article

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