Patients with psychogenic non-epileptic seizures referred to a tertiary epilepsy centre: Patient characteristics in relation to diagnostic delay

Clinical Neurology and Neurosurgery

Volumn 114, Issue 3, 2012, Pages 217-222

  Bodde, N M G ^a   Lazeron, R H C ^a   Wirken, J M A ^a   Van Der Kruijs, S J ^a   Aldenkamp, A P ^a,b   Boon, P A J M ^a,c  

^a EPILEPSY CENTER KEMPENHAEGHE   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

Delayed diagnosis; Non epileptic attack disorder; Patient characteristics; Patient history; Psychiatric comorbidity; Referral patterns; Somatoform disorders

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; COHORT ANALYSIS; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL SPECIALIST; PATIENT REFERRAL; PSYCHOGENIC NONEPILEPTIC SEIZURE; SEIZURE; SYMPTOM;

ADOLESCENT; ADULT; AGE FACTORS; AGE OF ONSET; COHORT STUDIES; COMORBIDITY; DELAYED DIAGNOSIS; EDUCATIONAL STATUS; ELECTROENCEPHALOGRAPHY; EPILEPSY; FEMALE; HUMANS; INDEPENDENT LIVING; MALE; MENTAL DISORDERS; MIDDLE AGED; REFERRAL AND CONSULTATION; SEIZURES; SEX FACTORS; SOMATOFORM DISORDERS; TIME FACTORS; YOUNG ADULT;

EID: 84857789555     PISSN: 03038467     EISSN: 18726968     Source Type: Journal    
DOI: 10.1016/j.clineuro.2011.10.019     Document Type: Article

References (62)

1. A.A. Leis, M.A. Ross, and A.K. Summers Psychogenic seizures: ictal characteristics and diagnostic pitfalls Neurology 42 1992 95 99
2. N.M.G. Bodde, J.L. Brooks, G.A. Baker, P.A.J.M. Boon, J.G.M. Hendriksen, and A.P. Aldenkamp Psychogenic nonepileptic seizures - diagnostic issues: a critical review Clinical Neurology and Neurosurgery 111 2009 1 9
3. N.M.G. Bodde, J.L. Brooks, G.A. Baker, P.A.J.M. Boon, J.G.M. Hendriksen, and O.G. Mulder Psychogenic non-epileptic seizures - definition, etiology, treatment and prognostic issues: a critical review Seizure 18 2009 543 553
4. K.R. Sigurdardottir, and E. Olafsson Incidence of psychogenic seizures in adults: a population-based study in Iceland Epilepsia 39 1998 749 752 (Pubitemid 28319512)
5. M. Reuber, and C.E. Elger Psychogenic non-epileptic seizures: review and update Epilepsy & Behavior 4 3 2003 205 216 (Pubitemid 37184595)
6. A. Abubakr, A. Kablinger, and G. Caldito Psychogenic seizures: clinical features and psychological analysis Epilepsy & Behavior 4 2003 241 245 (Pubitemid 37184599)
7. E. Baills, L. Pintor, X. Torres, E. Fernández-Egea, J. De Pablo, and S. Arroyo Psychiatric disease in patients with psychogenic non-epileptic seizures referred from an epilepsy unit in a general hospital Actas Españolas de Pisquiatría 32 2004 76 81 (Pubitemid 38535197)
8. K. Alper Nonepleptic seizures Neurologic Clinics (Epilepsy II: Special Issues) 12 1994 153 173
9. J. Iriarte, J. Parra, E. Urrestarazu, and J. Kuyk Controversies in the diagnosis and management of psychogenic pseudoseizures Epilepsy & Behavior 4 2003 354 359 (Pubitemid 37184614)
10. S.R. Benbadis, V. Agrawal, and W.O. Tatum How many patients with psychogenic nonepileptic seizures also have epilepsy? Neurology 57 2001 915 917 (Pubitemid 32845523)
11. W.C. LaFrance, and O. Devinsky The treatment of nonepileptic seizures: historical perspectives and future directions Epilepsia 45 2004 15 21 (Pubitemid 38856386)
12. M. Berkhoff, R.S. Briellmann, B.P. Radanov, F. Donati, and C.W. Hess Developmental background and outcome in patients with nonepileptic versus epileptic seizures: a controlled study Epilepsia 39 1998 463 469 (Pubitemid 28221800)
13. R.L. Marchetti, D. Kurcgant, J.G. Neto, M.A. Von Bismark, L.B. Marchetti, and L.A. Fiore Psychiatric diagnoses of patients with psychogenic non-epileptic seizures Seizure 17 2008 247 253 (Pubitemid 351330199)
14. S. Saygi, A. Katz, D.A. Marks, and S.S. Spencer Frontal lobe partial seizures and psychogenic seizures: comparison of clinical and ictal characteristics Neurology 42 1992 1274 1277
15. T.M. Alsaadi, C. Thieman, A. Shatzel, and S. Farias Video-EEG telemetry can be a crucial tool for neurologists experienced in epilepsy when diagnosing seizure disorders Seizure 13 2004 32 34 (Pubitemid 38139662)
16. N. Fejerman Nonepileptic disorders imitating generalized idiopathic epilepsies Epilepsia 46 2005 80 83 (Pubitemid 44921983)
17. A.V. Marquez, S.T. Farias, M. Apperson, S. Koopmans, J. Jorgensen, and A. Shatzel Psychogenic nonepileptic seizures are associated with an increased risk of obesity Epilepsy & Behavior 5 2004 88 93 (Pubitemid 38937069)
18. J. Kuyk, F. Leijten, H. Meinardi, P. Spinhoven, and R. van Dyck The diagnosis of psychogenic non-epileptic seizures: a review Seizure 6 4 1997 243 253 (Pubitemid 27399774)
19. E.S. Bowman, and O.N. Markand Psychodynamics and psychiatric diagnoses of pseudoseizure subjects American Journal of Psychiatry 153 1 1996 57 63 (Pubitemid 26026158)
20. G. Baslet, A. Roiko, and E. Prensky Heterogeneity in psychogenic nonepileptic seizures: understanding the role of psychiatric and neurologic factors Epilepsy & Behavior 17 2010 236 241
21. G.P. Prigatano, C.M. Stonnington, and R.S. Fisher Psychological factors in the genesis and management of nonepileptic seizures: clinical observations Epilepsy & Behavior 3 2002 343 349 (Pubitemid 35256233)
22. C.A. Galimberti, M.T. Ratti, R. Murelli, E. Marchioni, R. Manni, and A. Tartara Patients with psychogenic nonepileptic seizures, alone or epilepsy-associated, share a psychological profile distinct from that of epilepsy patients Journal of Neurology 250 2003 338 346 (Pubitemid 36399275)
23. M.E. Drake, A. Pakalnis, and B.B. Phillips Neuropsychological and psychiatric correlates of intractable pseudoseizures Seizure 1 1992 11 13
24. D.E. Cragar, D.T.R. Berry, F.A. Schmitt, and T.A. Fakhoury Cluster analysis of normal personality traits in patients with psychogenic nonepileptic seizures Epilepsy & Behavior 6 2005 593 600 (Pubitemid 40674287)
25. M. Reuber, R. Pukrop, J. Bauer, R. Derfuss, and C.E. Elger Multidimensional assessment of personality in patients with psychogenic non-epileptic seizures Journal of Neurology, Neurosurgery & Psychiatry 75 2004 743 748 (Pubitemid 38526687)
26. S. Riggio Psychogenic seizures Emergency Medicine Clinics of North America 12 1994 1001 1012 (Pubitemid 24363852)
27. E. Wyllie, D. Friedman, H. Lüders, H. Morris, D. Rothner, and J. Turnbull Outcome of psychogenic seizures in children and adolescents compared with adults Neurology 41 1991 742 744
28. N.M.G. Bodde, A.M. Janssen, C. Theuns, J.F. Vanhoutvin, P.A. Boon, and A.P. Aldenkamp Factors involved in the long-term prognosis of psychogenic nonepileptic seizures Journal of Psychosomatic Research 62 2007 545 551 (Pubitemid 46635473)
29. T. Lempert, and D. Schmidt Natural history and outcome of psychogenic seizures: a clinical study in 50 patients Journal of Neurology 237 1990 35 38 (Pubitemid 20072852)
30. H. Meierkord, B. Will, D. Fish, and S. Shorvon The clinical features and prognosis of pseudoseizures diagnosed using video-EEG telemetry Neurology 41 1991 1643 1646
31. K. Mökleby, S. Blomhoff, U.F. Malt, A. Dahlstrom, E. Tauboll, and L. Gjerstad Psychiatric comorbidity and hostility in patients with psychogenic nonepileptic seizures compared with somatoform disorders and healthy controls Epilepsia 43 2002 193 198 (Pubitemid 34226002)
32. R.S. Stewart, R. Lovitt, and R. Malcolm Stewart Are hysterical seizures more than hysteria? A research diagnostic criteria, DSM-III, and psychometric analysis American Journal of Psychiatry 139 7 1982 926 929 (Pubitemid 12096530)
33. T. Betts, and S. Boden Diagnosis, management and prognosis of a group of 128 patients with non-epileptic attack disorder. Part I Seizure 1 1992 19 26
34. J.P. Szaflarski, M. Szaflarski, C. Hughes, D.M. Ficker, W.T. Cahill, and M.D. Privitera Psychopathology and quality of life: psychogenic non-epileptic seizures versus epilepsy Medical Science Monitor 9 2003 113 118
35. S.V. Ramani, L.F. Quesney, D. Olson, and R.J. Gumnit Diagnosis of hysterical seizures in epileptic patients American Journal of Psychiatry 137 6 1980 705 709 (Pubitemid 10121000)
36. M. Reuber, and A.O. House Treating patients with psychogenic non-epileptic seizures Current Opinion in Neurology 15 2002 207 211 (Pubitemid 34286908)
37. L. D'Alessio, B. Giagante, S. Oddo, W.W. Silva, P. Solis, and D. Consalvo Psychiatric disorders in patients with psychogenic non-epileptic seizures, with and without comorbid epilepsy Seizure 15 5 2006 333 339 (Pubitemid 43840883)
38. G. Baslet, A. Roiko, and E. Prensky Heterogeneity in psychogenic nonepileptic seizures: understanding the role of psychiatric and neurological factors Epilepsy & Behavior 17 2 2010 236 241
39. A.B. Ettinger, O. Devinsky, D.M. Weisbrot, R.K. Ramakrishna, and A. Goyal A comprehensive profile of clinical, psychiatric, and psychosocial characteristics of patients with psychogenic nonepileptic seizures Epilepsia 40 9 1999 1292 12998
40. M. Reuber, G. Fernández, J. Bauer, C. Helmstaedter, and C.E. Elger Diagnostic delay in psychogenic nonepileptic seizures Neurology 58 2002 493 495 (Pubitemid 34150935)
41. S. Carton, P.J. Thompson, and J.S. Duncan Non-epileptic seizures: patient's understanding and reaction to the diagnosis and impact on outcome Seizure 12 2003 287 294 (Pubitemid 36806074)
42. M.J. Jongsma, J.M. Mommers, W.O. Renier, and H. Meinardi Follow-up of psychogenic, non-epileptic seizures: a pilot study - experience in a Dutch special centre for epilepsy Seizure 8 1999 146 148 (Pubitemid 29255502)
43. J. Kuyk, L. Dunki Jacobs, A.P. Aldenkamp, H. Meinardi, P. Spinhoven, and R. van Dyck Pseudo-epileptic seizures: hypnosis as a diagnostic tool Seizure 4 1995 123 128
44. T. Müller, M. Merschhemke, C. Dehnicke, M. Sanders, and H.J. Meencke Improving diagnostic procedure and treatment in patients with non-epileptic seizures (NES) Seizure 11 2002 85 89 (Pubitemid 34567554)
45. S.G. Jones, T.J. O' Brien, S.J. Adams, R. Mocellin, C.J. Kilpatrick, and R. Yerra Clinical characteristics and outcome in patients with psychogenic nonepileptic seizures Psychosomatic Medicine 72 2010 487 497
46. A. Wingen, and F. Otten Trends in consultaties huisarts, specialist en fysiotherapeut door ouderen Centraal Bureau voor de Statistiek/Statistics Netherlands 8 2006 4 91
47. Kuyk J. Pseudo-epileptic seizures: differential diagnosis and psychological characteristics. Doctoral dissertation. The Netherlands: VU University Amsterdam; 1999. Retrieved from: paper version.
48. S.R. Benbadis Psychogenic nonepileptic seizures. EMedicine from WebMD 2010 Retrieved from: http://emedicine.medscape.com/article/1184694-treatment
49. Moene F. Hypnosis and conversion disorder. Doctoral dissertation. The Netherlands: KUN Nijmegen; 2001. Retrieved from: paper version.
50. Z.J. Lipowski Somatization: the concept and its clinical application American Journal of Psychiatry 145 11 1988 1358 1368 (Pubitemid 18267374)
51. R.L. Woolfolk, L.A. Allen, and J.E. Tiu New directions in the treatment of somatization Psychiatric Clinics of North America 2 30 2007 1 644
52. E.S. Gregory, and G. Oye Stability of somatization disorder and somatization symptoms among primary care patients Archives of General Psychiatry 56 1999 90 95
53. S.S. O'Sullivan, J.E. Spillane, E.M. McMahon, B.J. Sweeney, R.J. Galvin, and B. McNamara Clinical characteristics and outcome of patients diagnosed with psychogenic nonepileptic seizures: a 5-year review Epilepsy & Behavior 11 2007 77 84 (Pubitemid 47087197)
54. K. Alper, O. Devinsky, K. Perrine, B. Vazquez, and D. Luciano Psychiatric classification of nonconversion nonepileptic seizures Archives of Neurology 52 1995 199 201
55. M. Reuber, A. House, R. Pukrop, J. Bauer, and E.C. Elger Somatization, dissociation and general psychopathology in patients with psychogenic non-epileptic seizures Epilepsy Research 57 2003 159 167 (Pubitemid 38167732)
56. DSM-IV diagnostic and statistical manual of mental disorders fourth edition 1994 American Psychiatric Association Washington, DC
57. G.E. Simon, and M. Von Korff Recall of psychiatric history in cross-sectional surveys: implications for epidemiologic research Epidemiologic Reviews 17 1995 221 227
58. G.E. Simon, and O. Gureje Stability of somatisation disorder and somatisation symptoms among primary care patients Archives of General Psychiatry 56 1999 90 95 (Pubitemid 29055055)
59. R.J. Brown Medically unexplained symptoms: a new model Psychiatry 5 2006 43 47 (Pubitemid 44883237)
60. V. De Gucht, and S. Maes Explaining medically unexplained symptoms: towards a multidimensional, theory based approach to somatisation Journal of Psychosomatic Research 60 2006 349 352
61. L.H. Goldstein, C. Drew, J. Mellers, S. Mitchell-O'Malley, and D.A. Oakly Dissociation, hypnotizability, coping styles and health locus of control: characteristics of pseudoseizure patients Seizure 9 2000 314 322
62. M. Reuber, A.J. Mitchell, S.J. Howlett, H.L. Crimlisk, and R.A. Grünewald Functional symptoms in neurology: questions and answers Journal of Neurology, Neurosurgery & Psychiatry 76 2005 307 314 (Pubitemid 40299115)