Review of cases of prolonged QTC and wave burst arrhythmia in patients treated with methadone;Revue des cas d'allongements du QTC et de torsades de pointe chez des patients traités par méthadone

Encephale

Volumn 38, Issue 1, 2012, Pages 58-63

  Laqueille, X ^a   Richa, S ^b   Kerbage, H ^b   Scart Gres, C ^c   Berleur, M P ^d  

^a CENTRE HOSPITALIER SAINTE ANNE   (France)

^b Faculté de Médecine de Saint Joseph   (Lebanon)

^c Pharmacie Centrale de l'Assistance Publique Hôpitaux de Paris ^*

^d ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

Author keywords

Death; Methadone; QTc; Wave burst arrhythmia

Indexed keywords

ANTIARRHYTHMIC AGENT; ANTIFUNGAL AGENT; ANTIRETROVIRUS AGENT; CORTICOSTEROID; CYTOCHROME P450 3A4; MACROLIDE; METHADONE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SEROTONIN UPTAKE INHIBITOR; TRICYCLIC ANTIDEPRESSANT AGENT;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; BRADYCARDIA; DRUG METABOLISM; ELECTROLYTE DISTURBANCE; HEART ARRHYTHMIA; HUMAN; QT PROLONGATION;

ADULT; ANALGESICS, OPIOID; DEATH, SUDDEN, CARDIAC; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; DRUG THERAPY, COMBINATION; ELECTROCARDIOGRAPHY; FEMALE; HUMANS; HYPOKALEMIA; LONG QT SYNDROME; MALE; METHADONE; OPIATE SUBSTITUTION TREATMENT; OPIOID-RELATED DISORDERS; RISK FACTORS;

EID: 84857786998     PISSN: 00137006     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.encep.2011.02.005     Document Type: Article

References (42)

1. A. Almehmi, A.M. Malas, and M. Yousufuddin Methadone-induced torsades de pointes in a patient with normal baseline QT interval W V Med J 100 4 2004 147 148
2. K. Anchersen, T. Clausen, and M. Gossop Prevalence and clinical relevance of corrected QT interval prolongation during methadone and buprenorphine treatment: a mortality assesment study Addiction 104 6 2009 993 999
3. P. Bittar, V. Piguet, and J. Kondo-Oestreicher Methadone induced long QTc and torsade de pointe Forum Med Suisse suppl 8 2002 36
4. A. Byrne, P. Cohen, and G. Girgis Letters, comments and response concerns about guidelines for QTc interval screening in methadone treatment Ann Intern Med 151 3 2009 216 219
5. R.A. Cruciani, R. Sekine, and P. Homel Measurement of QTc in patients receiving chronic methadone therapy J Pain Symptom Manage 29 4 2005 385 391 (Pubitemid 40602519)
6. D. De Bels, M. Staroukine, and J. Devriendt Torsades de pointes dues à la méthadone Ann Intern Med 139 2 2003 E 156
7. J.A. Decerf, B. Gressens, and C. Brohet Can methadone prolong the QT interval? Intense Care Med 30 8 2004 1690 1691
8. G.B. Ehret, C. Voide, and M. Gex-Fabry Drug-induced long QT syndrome in injection drug users receiving methadone: high frequency in hospitalized patients and risk factors Arch Intern Med 166 12 2006 1280 1287 (Pubitemid 43967579)
9. S. Fanoe, C. Hvidt, and P. Ege Syncope and QT prolongation among patients treated with methadone for heroin dependence in the city of Copenhagen Heart 93 9 2007 1051 1055 (Pubitemid 47310981)
10. F. Fonseca, J. Marti-Amlor, and A. Pastor Prevalence of long QTc interval in methadone maintenance patients Drug Alcohol Depend 99 1-3 2009 327 332
11. O.M. Fredheim, P.C. Borchgrevink, and L. Hegrenaes Opioid switching from morphine to methadone causes a minor but not clinically significant increase in QTc time: a prospective 9-month follow-up study J Pain Symptom Manage 32 2 2006 180 185 (Pubitemid 44131648)
12. M. Gil, M. Sala, and I. Anquera QT prolongation and torsades de pointes in patients infected with human immunodeficiency virus and treated with methadone Am J Cardiol 92 8 2003 995 997 (Pubitemid 37214820)
13. A. Huber, W. Ling, and J. Fradis Comparison of the effects of methadone and LAAM on the electrocardiogram Abstract Drug Alcohol Depend 63 S 2001 70
14. J.H. Indik A 38-year-old woman with dizziness Cardiol Rev 12 2 2004 63 64 (Pubitemid 38294868)
15. A.N. Katchman, K.A. McGroary, and M.J. Kilburn Influence of opioid agonists on cardiac human ether-a-go-go-related gene K+ currents J Pharmacol Exp Ther 303 2 2002 688 694 (Pubitemid 35231242)
16. C.A. Kornick, M.J. Kilborn, and J. Santiago-Palma QTc interval prolongation associated with intravenous methadone Pain 105 3 2003 499 506 (Pubitemid 37186911)
17. M.J. Krantz, L. Lewkowiez, and H. Hays Torsades de pointe associated with very high dose methadone Ann Intern Med 137 6 2002 501 505
18. M.J. Krantz, I.B. Kutinsky, and A.M. Robertson Dose-related effects of methadone on QT prolongation in a series of patients with torsade de pointes Pharmacotherapy 23 6 2003 802 805 (Pubitemid 36629083)
19. M.J. Krantz, C.M. Lowery, and B.A. Martell Effects of methadone on interval dispersion Pharmacotherapy 25 11 2005 1523 1529
20. M.J. Krantz, J. Martin, and B. Stimmel QTc interval screening in methadone treatment Ann Intern Med 150 6 2009 387 395
21. S.B. Leavitt, M. Shindermann, and S. Maxwell When enough is not enough: new perspectives on optimal methadone maintenance dose Mt Sinaï J Med 67 5-6 2000 404 411
22. Leavitt SB. Does methadone maintenance treatment affect heart health? Special report. Addiction treatment forum, 2001.
23. A. Lucchini, G. Barbaro, and F. Barbarini Methadone and QT prolongation in HIV infected patients Am J Cardiol 92 8 2004 995 997
24. L. Mantelli, V. Corti, and R. Bini Effects of dl-methadone on the response to physiological transmitters and on several functional parameters of the isolated guinea-pig heart Arch Int Pharmacodyn Ther 282 2 1986 298 313 (Pubitemid 16036958)
25. I. Maremmani, M. Pacini, and C. Cesaroni QTc interval prolongation in patients on long term methadone maintenance therapy Eur Addict Res 11 1 2005 44 49 (Pubitemid 40082210)
26. B.A. Martell, J.H. Arnsten, and B. Ray The impact of methadone induction on cardiac conduction in opiate users Ann Intern Med 139 2 2003 154 155 (Pubitemid 38129111)
27. B.A. Martell, J.H. Arnsten, and M.J. Krantz Impact of methadone treatment on cardiac repolarization and conduction in opioid users Am J Cardiol 95 7 2005 915 918 (Pubitemid 40386816)
28. E.O. Mokwe, and O. Ositadinma Torsade de pointe due to methadone Ann Intern Med 139 4 2003 W64
29. M. Pacini, I. Maremmani, and A.G.I. Maremmani Opioid treatement and «Long-QT Syndrome (LQTS)». A critical review of the literature Heroin Addict Relat Probl 11 4 2009 21 28
30. P.P. Pani Management of cardiac risk during methadone treatment: Focus on the QT interval Heroin Addict Relat Probl 11 4 2009 29 33 [21-8]
31. E. Peles, G. Bodner, and M.J. Kreek Corrected QT intervals as related to methadone dose and serum level in methadone maintenance treatment (MMT) patients: a cross sectional study Addiction 102 2 2007 289 300 (Pubitemid 46096291)
32. V. Piguet, J. Desmeules, and G. Ehret QT interval prolongation in patients on methadone with concomitant drugs J Clin Pharmacol 24 4 2004 446 448 (Pubitemid 38944145)
33. L. Pimentel, and D. Mayo Chronic methadone therapy complicated by torsades de pointes: a case report J Emerg Med 34 3 2008 287 290 (Pubitemid 351374640)
34. D.M. Roden Drug-induced prolongation of the QT interval N Engl J Med 350 10 2004 1013 1022 (Pubitemid 38269278)
35. M. Sala, I. Anguera, and M. Cervantes Torsade de pointe due to methadone Ann Intern Med 139 4 2003 W64
36. Swissmedic, Institut Suisse des produits thérapeutiques Méthadone et risque dose-dépendant de prolongation de l'intervalle QT et de torsade de pointes - informations importantes pour les professionnels de la santé Swissmedic J 1 2004 19 20
37. J. Tamargo Drug induced torsade de pointes: from molecular biology to bedside Jpn J Pharmacol 83 1 2000 1 19 (Pubitemid 30352651)
38. A. Villa, V. Foresti, and F. Confalonieri Autonomic neuropathy and prolongation of QT interval in human immunodeficiency virus infection Clin Auton Res 5 1 1995 48 52
39. J.F. Vodoz, F. Jacquier, and O. Lamy Torsade de pointe, un effet secondaire grave et méconnu chez le toxicomane sous méthadone Praxis 92 41 2003 1748 1750 (Pubitemid 43175015)
40. P.W. Walker, D. Klein, and L. Kasza High dose methadone and ventricular arrhythmias: a report of three cases Pain 103 3 2003 321 324 (Pubitemid 36638820)
41. E.F. Wedam, G.E. Bigelow, and R.E. Johnson QT interval effects of methadone, levomethadyl and buprenorphine in a randomized trial Arch Intern Med 167 22 2007 69 75
42. D. Zeltser, D. Justo, and A. Halkin Torsade de pointe due to noncardiac drugs: most patients have easily identifiable risk factors Medicine (Baltimore) 82 4 2003 282 290 (Pubitemid 36859224)