Risk factors and treatment of childhood and adolescent Burkitt lymphoma/leukaemia

British Journal of Haematology

Volumn 156, Issue 6, 2012, Pages 730-743

  Miles, Rodney R ^a   Arnold, Staci ^b   Cairo, Mitchell S ^c  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

Adolescent; Burkitt leukaemia; Burkitt lymphoma; Children; Paediatric

Indexed keywords

ASPARAGINASE; CARMUSTINE; CISPLATIN; CYCLOPHOSPHAMIDE; CYTARABINE; DAUNORUBICIN; DEXAMETHASONE; DOXORUBICIN; ETOPOSIDE; METHOTREXATE; MICRORNA; PREDNISOLONE; PREDNISONE; TIOGUANINE; VINCRISTINE;

ADOLESCENCE; BURKITT LYMPHOMA; CANCER COMBINATION CHEMOTHERAPY; CANCER IMMUNOTHERAPY; CANCER INCIDENCE; CANCER RADIOTHERAPY; CANCER RISK; CANCER SURVIVAL; CHILDHOOD CANCER; CHROMOSOME ABERRATION; COMPARATIVE GENOMIC HYBRIDIZATION; CYTOGENETICS; DIFFERENTIAL DIAGNOSIS; DISEASE ASSOCIATION; DRUG DOSE ESCALATION; DRUG MEGADOSE; GENE EXPRESSION PROFILING; HISTOPATHOLOGY; HUMAN; IMMUNOPHENOTYPING; LARGE CELL LYMPHOMA; ONCOGENE MYC; PRIORITY JOURNAL; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; SURVIVAL RATE; TREATMENT INDICATION; TREATMENT RESPONSE; TUMOR LYSIS SYNDROME;

ADOLESCENT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BURKITT LYMPHOMA; CHILD; CHROMOSOME ABERRATIONS; COMPARATIVE GENOMIC HYBRIDIZATION; DIAGNOSIS, DIFFERENTIAL; GENE EXPRESSION PROFILING; HUMANS; IMMUNOPHENOTYPING; IMMUNOTHERAPY; NEOPLASM, RESIDUAL; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; TUMOR LYSIS SYNDROME;

EID: 84857784469     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2011.09024.x     Document Type: Review

References (49)

1. Anderson, J.R., Jenkin, R.D., Wilson, J.F., Kjeldsberg, C.R., Sposto, R., Chilcote, R.R., Coccia, P.F., Exelby, P.R., Siegel, S., Meadows, A.T. & Hammond, G.D. (1993) Long-term follow-up of patients treated with COMP or LSA2L2 therapy for childhood non-Hodgkin's lymphoma: a report of CCG-551 from the Childrens Cancer Group. Journal of Clinical Oncology, 11, 1024-1032.
2. Bowman, W.P., Shuster, J.J., Cook, B., Griffin, T., Behm, F., Pullen, J., Link, M., Head, D., Carroll, A., Berard, C. & Murphy, S. (1996) Improved survival for children with B-cell acute lymphoblastic leukemia and stage IV small noncleaved-cell lymphoma: a pediatric oncology group study. Journal of Clinical Oncology, 14, 1252-1261.
3. Burkitt, D. (1958) A sarcoma involving the jaws in African children. British Journal of Surgery, 46, 218-223.
4. Cairo, M.S. & Bishop, M. (2004) Tumour lysis syndrome: new therapeutic strategies and classification. British Journal of Haematology, 127, 3-11.
5. Cairo, M.S., Krailo, M.D., Morse, M., Hutchinson, R.J., Harris, R.E., Kjeldsberg, C.R., Kadin, M.E., Radel, E., Steinherz, L.J., Morris, E., Finlay, J.L. & Meadows, A.T. (2002) Long-term follow-up of short intensive multiagent chemotherapy without high-dose methotrexate ('Orange') in children with advanced non-lymphoblastic non-Hodgkin's lymphoma: a children's cancer group report. Leukemia, 16, 594-600.
6. Cairo, M.S., Gerrard, M., Sposto, R., Auperin, A., Pinkerton, C.R., Michon, J., Weston, C., Perkins, S.L., Raphael, M., McCarthy, K. & Patte, C. (2007) Results of a randomized international study of high-risk central nervous system B non-Hodgkin lymphoma and B acute lymphoblastic leukemia in children and adolescents. Blood, 109, 2736-2743.
7. Cairo, M.S., Coiffier, B., Reiter, A. & Younes, A. (2010a) Recommendations for the evaluation of risk and prophylaxis of tumour lysis syndrome (TLS) in adults and children with malignant diseases: an expert TLS panel consensus. British Journal of Haematology, 149, 578-586.
8. Cairo, M.S., Lynch, J.C., Harrison, L., Perkins, S.L., Shiramizu, B., Gross, T., Sanger, W. & Goldman, S. (2010b) Safety, pharmacokinetics (PK) and outcome following Rituximab (R) in combination with FAB chemotherapy in children and adolescents (C+A) with Stage III/IV (Group B) and BM+/CNS+ (Group C) mature B-NHL: A Children's Oncology Group Report. Journal of Clinical Oncology, 28, S9536. (Abstract).
9. Cairo, M.S., Sposto, R., Gerrard, M., Auperin, A., Goldman, S., Harrison, L., Pinkerton, C.R., Raphael, M., McCarthy, K., Perkins, S.L., Patte, C. & Committee, F.L.I.S. (2012) Advanced stage, elevated LDH and primary site, but not adolescent age (≥15 years), are associated with an increased risk of failure in children and adolescents with mature B-NHL: results of the FAB/LMB 96 study. Journal of Clinical Oncology, doi: JCO.2010.33.3369 [pii].
10. Capello, D., Scandurra, M., Poretti, G., Rancoita, P.M., Mian, M., Gloghini, A., Deambrogi, C., Martini, M., Rossi, D., Greiner, T.C., Chan, W.C., Ponzoni, M., Moreno, S.M., Piris, M.A., Canzonieri, V., Spina, M., Tirelli, U., Inghirami, G., Rinaldi, A., Zucca, E., Favera, R.D., Cavalli, F., Larocca, L.M., Kwee, I., Carbone, A., Gaidano, G. & Bertoni, F. (2009) Genome wide DNA-profiling of HIV-related B-cell lymphomas. British Journal of Haematology, 148, 245-255.
11. Coiffier, B., Lepage, E., Briere, J., Herbrecht, R., Tilly, H., Bouabdallah, R., Morel, P., Van Den Neste, E., Salles, G., Gaulard, P., Reyes, F., Lederlin, P. & Gisselbrecht, C. (2002) CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma. New England Journal of Medicine, 346, 235-242.
12. Coiffier, B., Altman, A., Pui, C.H., Younes, A. & Cairo, M.S. (2008) Guidelines for the management of pediatric and adult tumor lysis syndrome: an evidence-based review. Journal of Clinical Oncology, 26, 2767-2778.
13. Dave, S.S., Fu, K., Wright, G.W., Lam, L.T., Kluin, P., Boerma, E.J., Greiner, T.C., Weisenburger, D.D., Rosenwald, A., Ott, G., Muller-Hermelink, H.K., Gascoyne, R.D., Delabie, J., Rimsza, L.M., Braziel, R.M., Grogan, T.M., Campo, E., Jaffe, E.S., Dave, B.J., Sanger, W., Bast, M., Vose, J.M., Armitage, J.O., Connors, J.M., Smeland, E.B., Kvaloy, S., Holte, H., Fisher, R.I., Miller, T.P., Montserrat, E., Wilson, W.H., Bahl, M., Zhao, H., Yang, L., Powell, J., Simon, R., Chan, W.C. & Staudt, L.M. (2006) Molecular diagnosis of Burkitt's lymphoma. New England Journal of Medicine, 354, 2431-2442.
14. Diosdado, B., van de Wiel, M.A., Terhaar Sive Droste, J.S., Mongera, S., Postma, C., Meijerink, W.J., Carvalho, B. & Meijer, G.A. (2009) MiR-17-92 cluster is associated with 13q gain and c-myc expression during colorectal adenoma to adenocarcinoma progression. British Journal of Cancer, 101, 707-714.
15. Dong, H.Y. (2010) Agressive B-cell lymphomas: diffuse large B-cell lymphoma and Burkitt lymphoma. In: Neoplastic Hematopathology: Contemporary Hematology (ed. by D. Jones), Vol. Part 3, pp. 303-322. Humana Press, New York.
16. Epstein, M.A., Achong, B.G. & Barr, Y.M. (1964) Virus particles in cultured lymphoblasts from Burkitt's lymphoma. Lancet, 1, 702-703.
17. Frazer, J.K., Goldman, S.C., Harrison, L., Perkins, S.L. & Cairo, M.S. (2011) Excellent outcome of CNS-positive pediatric Burkitt lymphoma and other mature B-NHL treated with cobmined chemo-immunotherapy (rituximab + FAB Group C) without CNS radiation: a Children's Oncology Group report. Annals of Oncology, 22, 278. (abstract).
18. Goldman, S.C., Holcenberg, J.S., Finklestein, J.Z., Hutchinson, R., Kreissman, S., Johnson, F.L., Tou, C., Harvey, E., Morris, E. & Cairo, M.S. (2001) A randomized comparison between rasburicase and allopurinol in children with lymphoma or leukemia at high risk for tumor lysis. Blood, 97, 2998-3003.
19. Griffin, T.C., Weitzman, S., Weinstein, H., Chang, M., Cairo, M., Hutchison, R., Shiramizu, B., Wiley, J., Woods, D., Barnich, M. & Gross, T.G. (2009) A study of rituximab and ifosfamide, carboplatin, and etoposide chemotherapy in children with recurrent/refractory B-cell (CD20 +) non-Hodgkin lymphoma and mature B-cell acute lymphoblastic leukemia: a report from the Children's Oncology Group. Pediatric Blood & Cancer, 52, 177-181.
20. Habermann, T.M., Weller, E.A., Morrison, V.A., Gascoyne, R.D., Cassileth, P.A., Cohn, J.B., Dakhil, S.R., Woda, B., Fisher, R.I., Peterson, B.A. & Horning, S.J. (2006) Rituximab-CHOP versus CHOP alone or with maintenance rituximab in older patients with diffuse large B-cell lymphoma. Journal of Clinical Oncology, 24, 3121-3127.
21. Hammond, S.M. (2006) MicroRNAs as oncogenes. Current Opinion in Genetics and Development, 16, 4-9.
22. Hayashita, Y., Osada, H., Tatematsu, Y., Yamada, H., Yanagisawa, K., Tomida, S., Yatabe, Y., Kawahara, K., Sekido, Y. & Takahashi, T. (2005) A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Research, 65, 9628-9632.
23. He, L., Thomson, J.M., Hemann, M.T., Hernando-Monge, E., Mu, D., Goodson, S., Powers, S., Cordon-Cardo, C., Lowe, S.W., Hannon, G.J. & Hammond, S.M. (2005) A microRNA polycistron as a potential human oncogene. Nature, 435, 828-833.
24. Hochberg, J., Waxman, I.M., Kelly, K.M., Morris, E. & Cairo, M.S. (2009) Adolescent non-Hodgkin lymphoma and Hodgkin lymphoma: state of the science. British Journal of Haematology, 144, 24-40.
25. Hummel, M., Bentink, S., Berger, H., Klapper, W., Wessendorf, S., Barth, T.F., Bernd, H.W., Cogliatti, S.B., Dierlamm, J., Feller, A.C., Hansmann, M.L., Haralambieva, E., Harder, L., Hasenclever, D., Kuhn, M., Lenze, D., Lichter, P., Martin-Subero, J.I., Moller, P., Muller-Hermelink, H.K., Ott, G., Parwaresch, R.M., Pott, C., Rosenwald, A., Rosolowski, M., Schwaenen, C., Sturzenhofecker, B., Szczepanowski, M., Trautmann, H., Wacker, H.H., Spang, R., Loeffler, M., Trumper, L., Stein, H. & Siebert, R. (2006) A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling. New England Journal of Medicine, 354, 2419-2430.
26. Jaffe, E.S., Harris, N.L., Stein, H. & Vardiman, J.W. (eds.) (2001) Pathology and Genetics, Tumours of Haematopoietic and Lymphoid Tissues. IARC Press, Lyon, France.
27. Klapper, W., Szczepanowski, M., Burkhardt, B., Berger, H., Rosolowski, M., Bentink, S., Schwaenen, C., Wessendorf, S., Spang, R., Moller, P., Hansmann, M.L., Bernd, H.W., Ott, G., Hummel, M., Stein, H., Loeffler, M., Trumper, L., Zimmermann, M., Reiter, A. & Siebert, R. (2008) Molecular profiling of pediatric mature B-cell lymphoma treated in population-based prospective clinical trials. Blood, 112, 1374-1381.
28. Lones, M.A., Sanger, W.G., Le Beau, M.M., Heerema, N.A., Sposto, R., Perkins, S.L., Buckley, J., Kadin, M.E., Kjeldsberg, C.R., Meadows, A., Siegel, S., Finlay, J., Bergeron, S. & Cairo, M.S. (2004) Chromosome abnormalities may correlate with prognosis in Burkitt/Burkitt-like lymphomas of children and adolescents: a report from Children's Cancer Group Study CCG-E08. Journal of Pediatric Hematology/Oncology, 26, 169-178.
29. Marcus, R., Imrie, K., Belch, A., Cunningham, D., Flores, E., Catalano, J., Solal-Celigny, P., Offner, F., Walewski, J., Raposo, J., Jack, A. & Smith, P. (2005) CVP chemotherapy plus rituximab compared with CVP as first-line treatment for advanced follicular lymphoma. Blood, 105, 1417-1423.
30. Meinhardt, A., Burkhardt, B., Zimmermann, M., Borkhardt, A., Kontny, U., Klingebiel, T., Berthold, F., Janka-Schaub, G., Klein, C., Kabickova, E., Klapper, W., Attarbaschi, A., Schrappe, M. & Reiter, A. (2010) Phase II window study on rituximab in newly diagnosed pediatric mature B-cell non-Hodgkin's lymphoma and Burkitt leukemia. Journal of Clinical Oncology, 28, 3115-3121.
31. Murphy, S.B. (1980) Classification, staging and end results of treatment of childhood non-Hodgkin's lymphomas: dissimilarities from lymphomas in adults. Seminars in Oncology, 7, 332-339.
32. Mussolin, L., Pillon, M., d'Amore, E.S., Conter, V., Piglione, M., Lo Nigro, L., Garaventa, A., Buffardi, S., Arico, M. & Rosolen, A. (2011) Minimal disseminated disease in high-risk Burkitt's lymphoma identifies patients with different prognosis. Journal of Clinical Oncology, 29, 1779-1784.
33. Nelson, M., Perkins, S.L., Dave, B.J., Coccia, P.F., Bridge, J.A., Lyden, E.R., Heerema, N.A., Lones, M.A., Harrison, L., Cairo, M.S. & Sanger, W.G. (2009) An increased frequency of 13q deletions detected by fluorescence in situ hybridization and its impact on survival in children and adolescents with Burkitt lymphoma: results from the Children's Oncology Group study CCG-5961. British Journal of Haematology, 148, 600-610.
34. Onciu, M., Schlette, E., Zhou, Y., Raimondi, S.C., Giles, F.J., Kantarjian, H.M., Medeiros, L.J., Ribeiro, R.C., Pui, C.H. & Sandlund, J.T. (2006) Secondary chromosomal abnormalities predict outcome in pediatric and adult high-stage Burkitt lymphoma. Cancer, 107, 1084-1092.
35. Patte, C., Philip, T., Rodary, C., Bernard, A., Zucker, J.M., Bernard, J.L., Robert, A., Rialland, X., Benz-Lemoine, E., Demeocq, F., Caillou, B. & Lemerle, J. (1986) Improved survival rate in children with stage III and IV B cell non-Hodgkin's lymphoma and leukemia using multi-agent chemotherapy: results of a study of 114 children from the French Pediatric Oncology Society. Journal of Clinical Oncology, 4, 1219-1226.
36. Patte, C., Philip, T., Rodary, C., Zucker, J.M., Behrendt, H., Gentet, J.C., Lamagnere, J.P., Otten, J., Dufillot, D., Pein, F., Caillou, B. & Lemerle, J. (1991) High survival rate in advanced-stage B-cell lymphomas and leukemias without CNS involvement with a short intensive polychemotherapy: results from the French Pediatric Oncology Society of a randomized trial of 216 children. Journal of Clinical Oncology, 9, 123-132.
37. Patte, C., Auperin, A., Michon, J., Behrendt, H., Leverger, G., Frappaz, D., Lutz, P., Coze, C., Perel, Y., Raphael, M. & Terrier-Lacombe, M.J. (2001) The Societe Francaise d'Oncologie Pediatrique LMB89 protocol: highly effective multiagent chemotherapy tailored to the tumor burden and initial response in 561 unselected children with B-cell lymphomas and L3 leukemia. Blood, 97, 3370-3379.
38. Patte, C., Auperin, A., Gerrard, M., Michon, J., Pinkerton, R., Sposto, R., Weston, C., Raphael, M., Perkins, S.L., McCarthy, K. & Cairo, M.S. (2007) Results of the randomized international FAB/LMB96 trial for intermediate risk B-cell non-Hodgkin lymphoma in children and adolescents: it is possible to reduce treatment for the early responding patients. Blood, 109, 2773-2780.
39. Piccaluga, P.P., De Falco, G., Kustagi, M., Gazzola, A., Agostinelli, C., Tripodo, C., Leucci, E., Onnis, A., Astolfi, A., Sapienza, M.R., Bellan, C., Lazzi, S., Tumwine, L., Mawanda, M., Ogwang, M., Calbi, V., Formica, S., Califano, A., Pileri, S.A. & Leoncini, L. (2011) Gene expression analysis uncovers similarity and differences among Burkitt lymphoma subtypes. Blood, 117, 3596-3608.
40. Poirel, H.A., Cairo, M.S., Heerema, N.A., Swansbury, J., Auperin, A., Launay, E., Sanger, W.G., Talley, P., Perkins, S.L., Raphael, M., McCarthy, K., Sposto, R., Gerrard, M., Bernheim, A. & Patte, C. (2009) Specific cytogenetic abnormalities are associated with a significantly inferior outcome in children and adolescents with mature B-cell non-Hodgkin's lymphoma: results of the FAB/LMB 96 international study. Leukemia, 23, 323-331.
41. Salaverria, I., Zettl, A., Bea, S., Hartmann, E.M., Dave, S.S., Wright, G.W., Boerma, E.J., Kluin, P.M., Ott, G., Chan, W.C., Weisenburger, D.D., Lopez-Guillermo, A., Gascoyne, R.D., Delabie, J., Rimsza, L.M., Braziel, R.M., Jaffe, E.S., Staudt, L.M., Muller-Hermelink, H.K., Campo, E. & Rosenwald, A. (2008) Chromosomal alterations detected by comparative genomic hybridization in subgroups of gene expression-defined Burkitt's lymphoma. Haematologica, 93, 1327-1334.
42. Schiffman, J.D., Lorimer, P.D., Rodic, V., Jahromi, M.S., Downie, J.M., Bayerl, M.G., Sanmann, J.N., Althof, P.A., Sanger, W.G., Barnette, P., Perkins, S.L. & Miles, R.R. (2011) Genome wide copy number analysis of paediatric Burkitt lymphoma using formalin-fixed tissues reveals a subset with gain of chromosome 13q and corresponding miRNA over expression. British Journal of Haematology, 155, 477-486.
43. Scholtysik, R., Kreuz, M., Klapper, W., Burkhardt, B., Feller, A.C., Hummel, M., Loeffler, M., Rosolowski, M., Schwaenen, C., Spang, R., Stein, H., Thorns, C., Trumper, L., Vater, I., Wessendorf, S., Zenz, T., Siebert, R. & Kuppers, R. (2010) Detection of genomic aberrations in molecularly defined Burkitt's lymphoma by array-based, high resolution, single nucleotide polymorphism analysis. Haematologica, 95, 2047-2055.
44. Shiramizu, B., Goldman, S., Kusao, I., Agsalda, M., Lynch, J., Smith, L., Harrison, L., Morris, E., Gross, T.G., Sanger, W., Perkins, S. & Cairo, M.S. (2011) Minimal disease assessment in the treatment of children and adolescents with intermediate-risk (Stage III/IV) B-cell non-Hodgkin lymphoma: a children's oncology group report. British Journal of Haematology, 153, 758-763.
45. Sposto, R., Meadows, A.T., Chilcote, R.R., Steinherz, P.G., Kjeldsberg, C., Kadin, M.E., Krailo, M.D., Termuhlen, A.M., Morse, M. & Siegel, S.E. (2001) Comparison of long-term outcome of children and adolescents with disseminated non-lymphoblastic non-Hodgkin lymphoma treated with COMP or daunomycin-COMP: a report from the Children's Cancer Group. Medical and Pediatric Oncology, 37, 432-441.
46. Swerdlow, S.H., Campo, E., Harris, N.L., Jaffe, E.S., Pileri, S.A., Stein, H., Thiele, J. & Vardiman, J.W. (eds.) (2008) WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. IARC Press, Lyon, France.
47. Toujani, S., Dessen, P., Ithzar, N., Danglot, G., Richon, C., Vassetzky, Y., Robert, T., Lazar, V., Bosq, J., Da Costa, L., Perot, C., Ribrag, V., Patte, C., Wiels, J. & Bernheim, A. (2009) High resolution genome-wide analysis of chromosomal alterations in Burkitt's lymphoma. PLoS ONE, 4, e7089.
48. Waxman, I., Hochberg, J. & Cairo, M.S. (2011) Lymphoma. In: Nelson's Pediatric, 19th edn. (ed. by R. Kliegman, B. Stanton, J. St. Geme, N. Schor & R. Behrman), pp. 1739-1745. Elsevier Inc., Philadelphia.
49. Woessmann, W., Seidemann, K., Mann, G., Zimmermann, M., Burkhardt, B., Oschlies, I., Ludwig, W.D., Klingebiel, T., Graf, N., Gruhn, B., Juergens, H., Niggli, F., Parwaresch, R., Gadner, H., Riehm, H., Schrappe, M. & Reiter, A. (2005) The impact of the methotrexate administration schedule and dose in the treatment of children and adolescents with B-cell neoplasms: a report of the BFM Group Study NHL-BFM95. Blood, 105, 948-958.