Why Do Canadian Women Fail to Achieve Optimal Pre-Conceptional Folic Acid Supplementation? An Observational Study

Journal of Obstetrics and Gynaecology Canada

Volumn 33, Issue 11, 2011, Pages 1116-1123

  Miller, Elizabeth C ^a,b   Liu, Ning ^a   Wen, Shi Wu ^a,c   Walker, Mark ^a,c,d  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b QUEEN S UNIVERSITY   (Canada)

^c UNIVERSITY OF OTTAWA   (Canada)

^d Ontario Perinatal Surveillance System   (Canada)

Author keywords

Folic acid; Maternity Experiences Survey; Pre conception care

Indexed keywords

FOLIC ACID;

ADULT; ARTICLE; BIRTHPLACE; BODY MASS; CANADA; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; EDUCATIONAL STATUS; FEMALE; HEALTH CARE PERSONNEL; HUMAN; LANGUAGE; LOWEST INCOME GROUP; MATERNAL AGE; NEURAL TUBE DEFECT; OBESITY; OBSERVATIONAL STUDY; PREPREGNANCY CARE; RISK FACTOR; SMOKING; UNEMPLOYMENT; VITAMIN SUPPLEMENTATION; YOUNG ADULT; ADOLESCENT; DIET SUPPLEMENTATION; MATERNAL CARE; POVERTY; PREGNANCY; STATISTICS;

ADOLESCENT; ADULT; CANADA; CROSS-SECTIONAL STUDIES; DIETARY SUPPLEMENTS; EDUCATIONAL STATUS; FEMALE; FOLIC ACID; HUMANS; MATERNAL AGE; NEURAL TUBE DEFECTS; OBESITY; POVERTY; PRECONCEPTION CARE; PREGNANCY; RISK FACTORS;

EID: 84857780171     PISSN: 17012163     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1701-2163(16)35079-4     Document Type: Article

References (34)

1. Kaczorowski J., Lee L. Folic acid supplementation. What mothers say: the Canadian Maternity Experiences Survey of the Canadian Perinatal Surveillance System 2009, 57-62. Public Health Agency of Canada, Ottawa.
2. Bailey L.B. New standard for dietary folate intake among pregnant women. Am J Clin Nutr 2000, 71(Suppl):1304S-1307S.
3. Higgins J.R., Quinlivan E.P., McPartlin J., Scott J.M., Weir D.G., Darling M.R.N. The relationship between increased folate catabolism and the increased requirement for folate in pregnancy. BJOG 2000, 107:1149-1154.
4. Czeizel A.E., Dudas I., Metneki J. Pregnancy outcomes in a randomised controlled trial of periconceptional multivitamin supplementation. Arch Gynecol Obstet 1994, 255:131-139.
5. Lumley J., Watson L., Watson M., Bower C. Periconceptional supplementation with folate and/or multivitamins for preventing neural tube defects. Cochrane Database Syst Rev 2001, 3. Art. No.:CD001056.
6. De Wals P., Tairou F., Van Allen M.I., Uh S.H., Lowry R.B., Sibbald B., et al. Reduction in neural-tube defects after folic acid fortification in Canada. N Engl J Med 2007, 357:135-142.
7. Wilcox A.J., Lie R.T., Solvoll K., Taylor J., McConnaughey D.R., Abyholm F., et al. Folic acid supplements and risk of facial clefts: national population based case-control study. BMJ 2007, 334:464-467.
8. Wen S.W., Chen X., Rodger M., White R.R., Yang Q., Smith G.N., et al. Folic acid supplementation in early second trimester and the risk of preeclampsia. Am J Obstet Gynecol 2008, 198(45):e1-e7.
9. Thompson J.R., Fitz Gerald P., Willoughby M.L.N., Armstrong B.K. Maternal folate supplementation in pregnancy and protection against acute lymphoblastic leukaemia in childhood: a case-control study. Lancet 2001, 358:1935-1940.
10. McDonald S.D., Perkins S.L., Jodouin C.A., Walker M.C. Folate levels in pregnant women who smoke: an important gene/environment interaction. Am J Obstet Gynecol 2002, 187:620-625.
11. Wen S.W., Zhou J., Yang Q., Fraser W., Olatunbosun O., Walker M. Maternal exposure to folic acid antagonists and placenta-mediated adverse pregnancy outcomes. CMAJ 2008, 179:1263-1268.
12. Persad V.L., Van den Hof M.C., Dube J.M., Zimmer P. Incidence of open neural tube defects in Nova Scotia after folic acid fortification. CMAJ 2002, 167:241-245.
13. Godwin K.A., Sibbald B., Bedard T., Kuzeljevic B., Lowry R.B., Arbour L. Changes in frequencies of select congenital anomalies since the onset of folic acid fortification in a Canadian birth defect registry. Can J Public Health 2008, 99:271-275.
14. Liu S., West R., Randall E., Longerich L., O'Connor K.S., Scott H., et al. A comprehensive evaluation of food fortification with folic acid for the primary prevention of neural tube defects. BMC Pregnancy Childbirth 2004, 4:20. Available at:, Accessed March 3, 2011. http://www.biomedcentral.com/content/pdf/1471-2393-4-20.pdf.
15. Leon J.A., Evans J., Royle C. Prevalence of congenital anomalies. In: Canadian Perinatal Health Report, 2008 Edition. Public Health Agency of Canada 2008, 28:158-165.
16. Neimanis I.M., Paterson J.M., Bain E. Preventing neural tube defects: survey of preconceptional use of folic acid. Can Fam Physician 1999, 45:1717-1722.
17. Watson L.F., Brown S.J., Davey M.A. Use of periconceptional folic acid supplements in Victoria and New South Wales, Australia. Aus N Z J Public Health 2006, 30:42-49.
18. Why all women who could become pregnant should be taking folic acid. Folic acid 2008 information update 2008, Public Health Agency of Canada, Ottawa, Available at: http://www.phac-aspc.gc.ca/fa-af/ index-eng.php. Accessed December 28, 2010.
19. Kim M.H., Han J.Y., Cho Y.J., Ahn H.K., Kim J.O., Ryu H.M., et al. Factors associated with a positive intake of folic acid in the periconceptional period among Korean women. Public Health Nutr 2009, 12:468-471.
20. van Eijsden M., van der Wal M.F., Bonsel G.J. Folic acid knowledge and use in a multi-ethnic pregnancy cohort: the role of language proficiency. BJOG 2006, 113:1446-1451.
21. Carmichael S.L., Shaw G.M., Yang W., Laurent C., Herring A., Royle M.H., et al. Correlates of intake of folic acid-containing supplements among pregnant women. National Birth Defects Prevention Study. Am J Obstet Gynecol 2006, 194:203-210.
22. Binns C., Scott J., Nwafor N., Graham K., Oddy W., Lee A. Which mothers take folic acid and folate containing foods?. Asia Pac J Clin Nutr 2006, 15:335-340.
23. Brough L., Rees G.A., Crawford M.A., Dorman E.K. Social and ethnic differences in folic acid use preconception and during early pregnancy in the UK: effect on maternal folate status. J Hum Nutr Diet 2009, 22:100-107.
24. Hassan A.S., Al-Kharusi B.M. Knowledge and use of folic acid among pregnant Arabian women residing in Qatar and Oman. Int J Food Sci Nutr 2008, 59:70-79.
25. Mathews F., Yudkin P., Neil A. Folates in the periconceptional period: are women getting enough?. Br J Obstet Gynaecol 1998, 1059:954-959.
26. Li Z., Ren A., Zhang L., Liu J., Li Z. Periconceptional use of folic acid in Shanxi Province of northern China. Public Health Nutr 2007, 10:471-476.
27. Wu D.Y., Brat G., Milla G., Kim J. Knowledge and use of folic acid for prevention of birth defects amongst Honduran women. Reprod Toxicol 2007, 23:600-606.
28. Nilsen R.M., Vollset S.E., Gjessing H.K., Magnus P., Meltzer H.M., Haugen M., et al. Patterns and predictors of folic acid supplement use among pregnant women: the Norwegian Mother and Child Cohort Study. Am J Clin Nutr 2006, 84:1134-1141.
29. Dawson L.E., Pham B., Hunter A.G. Low rate of adequate folic acid supplementation in well-educated women of high socioeconomic status attending a genetics clinic. CMAJ 2001, 164:1149-1150.
30. Han A., Rotermann M., Fuller-Thomson E., Ray J.G. Pre-conceptional folic acid supplement use according to maternal country of birth. J Obstet Gynaecol Can 2009, 31:222-226.
31. Public Health Agency of Canada. The Canadian Maternity Experiences Survey. Ottawa: Public Health Agency of Canada. Available at:. Accessed March 3, 2011. http://www.phac-aspc.gc.ca/rhs-ssg/survey-eng.php.
32. Dzakpasu S., Kaczorov J., Chalmers B., Heaman M., Duggan J., Neusy E. The Canadian Maternity Experiences Survey: design and methods. J Obstet Gynaecol Can 2008, 30:207-216.
33. Petersen M.R., Deddens J.A. A comparison of two methods for estimating prevalence ratios. BMC Med Res Methodol 2008, 8:9.
34. Zou G. A modified Poisson regression approach to prospective studies with binary data. Am J Epidemiol 2004, 59:702-706.