Immediate versus delayed medical treatment for first-trimester miscarriage: A randomized trial

American Journal of Obstetrics and Gynecology

Volumn 206, Issue 3, 2012, Pages 215.e1-215.e6

  Torre, Antoine ^a,c   Huchon, Cyrille ^a,c   Bussieres, Laurence ^b   MacHevin, Elise ^a,c   Camus, Erick ^c   Fauconnier, Arnaud ^a,c  

^a LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

^b HÔPITAL AMBROISE PARÉ   (France)

^c CENTRE HOSPITALIER INTERCOMMUNAL   (France)

Author keywords

expectant management; mifepristone; miscarriage; misoprostol; randomized trial

Indexed keywords

CAFFEINE; MIFEPRISTONE; MISOPROSTOL; OPIATE; PARACETAMOL; PHLOROGLUCINOL; RHESUS D ANTIBODY; SPASMOLYTIC AGENT; TRIMETHYLPHLOROGLUCINOL; UNCLASSIFIED DRUG;

ADULT; BLEEDING; COMPARATIVE STUDY; CONFERENCE PAPER; CONTROLLED STUDY; EARLY INTERVENTION; EMERGENCY WARD; FEMALE; FEVER; FIRST TRIMESTER MISCARRIAGE; HUMAN; INFECTION; MAJOR CLINICAL STUDY; PAIN; PATIENT CARE; PREGNANCY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SPONTANEOUS ABORTION; THERAPY DELAY; TREATMENT FAILURE; VACUUM ASPIRATION;

EID: 84857752615     PISSN: 00029378     EISSN: 10976868     Source Type: Journal    
DOI: 10.1016/j.ajog.2011.12.009     Document Type: Conference Paper

References (29)

1. A.M. Nybo Andersen, J. Wohlfahrt, P. Christens, J. Olsen, M. Melbye Maternal age and fetal loss: population based register linkage study BMJ 320 2000 1708 1712
2. W.M. Ankum, M. Wieringa-De Waard, P.J. Bindels Management of spontaneous miscarriage in the first trimester: an example of putting informed shared decision making into practice BMJ 322 2001 1343 1346
3. S. Nielsen, M. Hahlin, J. Platz-Christensen Randomised trial comparing expectant with medical management for first trimester miscarriages Br J Obstet Gynaecol 106 1999 804 807
4. K. Forbes Management of first trimester spontaneous abortions BMJ 310 1995 1426
5. J.M. Shelley, D. Healy, S. Grover A randomised trial of surgical, medical and expectant management of first trimester spontaneous miscarriage Aust N Z J Obstet Gynaecol 45 2005 122 127
6. P.T. Wagaarachchi, P.W. Ashok, N. Narvekar, N.C. Smith, A. Templeton Medical management of early fetal demise using a combination of mifepristone and misoprostol Hum Reprod 16 2001 1849 1853
7. J. Trinder, P. Brocklehurst, R. Porter, M. Read, S. Vyas, L. Smith Management of miscarriage: expectant, medical, or surgical? Results of randomised controlled trial (miscarriage treatment (MIST) trial) BMJ 332 2006 1235 1240
8. K.M. Kollitz, L.A. Meyn, P.A. Lohr, M.D. Creinin Mifepristone and misoprostol for early pregnancy failure: a cohort analysis Am J Obstet Gynecol 204 2011 386.e1 386.e6
9. A. Sotiriadis, G. Makrydimas, S. Papatheodorou, J.P. Ioannidis Expectant, medical, or surgical management of first-trimester miscarriage: a meta-analysis Obstet Gynecol 105 2005 1104 1113
10. K. Nanda, A. Peloggia, D. Grimes, L. Lopez, G. Nanda Expectant care versus surgical treatment for miscarriage Cochrane Database Syst Rev 2006 CD003518
11. S. Petrou, J. Trinder, P. Brocklehurst, L. Smith Economic evaluation of alternative management methods of first-trimester miscarriage based on results from the MIST trial BJOG 113 2006 879 889
12. L.F. Smith, P.D. Ewings, C. Quinlan Incidence of pregnancy after expectant, medical, or surgical management of spontaneous first trimester miscarriage: long term follow-up of miscarriage treatment (MIST) randomised controlled trial BMJ 339 2009 b3827
13. E.T. de Jonge, J.D. Makin, E. Manefeldt, G.H. De Wet, R.C. Pattinson Randomised clinical trial of medical evacuation and surgical curettage for incomplete miscarriage BMJ 311 1995 662
14. A. Gronlund, L. Gronlund, L. Clevin, B. Andersen, N. Palmgren, O. Lidegaard Management of missed abortion: comparison of medical treatment with either mifepristone + misoprostol or misoprostol alone with surgical evacuation: a multi-center trial in Copenhagen county, Denmark Acta Obstet Gynecol Scand 81 2002 1060 1065
15. S. Nielsen, M. Hahlin, A. Moller, S. Granberg Bereavement, grieving and psychological morbidity after first trimester spontaneous abortion: comparing expectant management with surgical evacuation Hum Reprod 11 1996 1767 1770
16. G.C. Graziosi, B.W. Mol, P.J. Reuwer, A. Drogtrop, H.W. Bruinse Misoprostol versus curettage in women with early pregnancy failure after initial expectant management: a randomized trial Hum Reprod 19 2004 1894 1899
17. F. Blohm, B.E. Friden, I. Milsom, J.J. Platz-Christensen, S. Nielsen A randomised double blind trial comparing misoprostol or placebo in the management of early miscarriage BJOG 112 2005 1090 1095
18. M. Wieringa-De Waard, E.E. Hartman, W.M. Ankum, J.B. Reitsma, P.J. Bindels, G.J. Bonsel Expectant management versus surgical evacuation in first trimester miscarriage: health-related quality of life in randomized and non-randomized patients Hum Reprod 17 2002 1638 1642
19. J.S. Bagratee, V. Khullar, L. Regan, J. Moodley, H. Kagoro A randomized controlled trial comparing medical and expectant management of first trimester miscarriage Hum Reprod 19 2004 266 271
20. M.F. Reeves, P.A. Lohr, B.J. Harwood, M.D. Creinin Ultrasonographic endometrial thickness after medical and surgical management of early pregnancy failure Obstet Gynecol 111 2008 106 112
21. C. Lelaidier, C. Baton-Saint-Mleux, H. Fernandez, P. Bourget, R. Frydman Mifepristone (RU 486) induces embryo expulsion in first trimester non-developing pregnancies: a prospective randomized trial Hum Reprod 8 1993 492 495
22. C. Luise, K. Jermy, C. May, G. Costello, W.P. Collins, T.H. Bourne Outcome of expectant management of spontaneous first trimester miscarriage: observational study BMJ 324 2002 873 875
23. M. Wieringa-de Waard, J. Vos, G.J. Bonsel, P.J. Bindels, W.M. Ankum Management of miscarriage: a randomized controlled trial of expectant management versus surgical evacuation Hum Reprod 17 2002 2445 2450
24. D. Jurkovic, J.A. Ross, K.H. Nicolaides Expectant management of missed miscarriage Br J Obstet Gynaecol 105 1998 670 671
25. Royal College of Obstetricians and Gynaecologists The management of early pregnancy loss Green-top Guideline no. 25, 2006 http://www.rcog.org.uk/files/ rcog-corp/uploaded-files/GT25ManagementofEarlyPregnancyLoss2006.pdf Accessed Feb. 21, 2011
26. S. Petrou, E. McIntosh Women's preferences for attributes of first-trimester miscarriage management: a stated preference discrete-choice experiment Value Health 12 2009 551 559
27. A. Agostini, I. Ronda, M. Capelle, F. Romain, F. Bretelle, B. Blanc Influence of clinical and ultrasound factors on the efficacy of misoprostol in first trimester pregnancy failure Fertil Steril 84 2005 1030 1032
28. M.D. Creinin, X. Huang, C. Westhoff, K. Barnhart, J.M. Gilles, J. Zhang Factors related to successful misoprostol treatment for early pregnancy failure Obstet Gynecol 107 2006 901 907
29. M. Odeh, R. Tendler, M. Kais, O. Maximovsky, E. Ophir, J. Bornstein Early pregnancy failure: factors affecting successful medical treatment Isr Med Assoc J 12 2010 325 328