Too much fat for the gut's microbiota

Gut

Volumn 61, Issue 4, 2012, Pages 474-475

  Tilg, Herbert ^a   Marchesi, Julian R ^b  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL DEHYDROGENASE; INSULIN; PYRROLOQUINOLINEQUINONE;

BACTEROIDETES; DENATURING GRADIENT GEL ELECTROPHORESIS; DISEASE ACTIVITY; DISEASE ASSOCIATION; ENVIRONMENTAL FACTOR; ENZYME ACTIVITY; FIRMICUTES; GAMMAPROTEOBACTERIA; GENETIC ASSOCIATION; HOST PATHOGEN INTERACTION; HUMAN; INNATE IMMUNITY; INTESTINE FLORA; INTESTINE MUCOSA PERMEABILITY; MOLECULAR PATHOLOGY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NOTE; PHENOTYPE; PREVOTELLA; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; DIET, HIGH-FAT; INTESTINES; MALE; METAGENOME;

EID: 84857698491     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2011-301918     Document Type: Note

References (10)

1. Tilg H, Kaser A. Gut microbiome, obesity, and metabolic dysfunction. J Clin Invest 2011;121:2126-32.
2. Serino M, Luche E, Gres S, et al. Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota. Gut 2012;61:543-53.
3. Burcelin R, Crivelli V, Dacosta A, et al. Heterogeneous metabolic adaptation of C57BL/6J mice to high-fat diet. Am J Physiol Endocrinol Metab 2002;282: E834-42. (Pubitemid 34654745)
4. Greiner T, Backhed F. Effects of the gut microbiota on obesity and glucose homeostasis. Trends Endocrinol Metab 2011;22:117-23.
5. Cani PD, Bibiloni R, Knauf C, et al. Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes 2008;57:1470-81.
6. Cani PD, Neyrinck AM, Fava F, et al. Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia. Diabetologia 2007;50:2374-83. (Pubitemid 47512397)
7. Zhang H, DiBaise JK, Zuccolo A, et al. Human gut microbiota in obesity and after gastric bypass. Proc Natl Acad Sci U S A 2009;106:2365-70.
8. Vijay-Kumar M, Aitken JD, Carvalho FA, et al. Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5. Science 2010;328:228-31.
9. Letran SE, Lee SJ, Atif SM, et al. TLR5-deficient mice lack basal inflammatory and metabolic defects but exhibit impaired CD4 T cell responses to a flagellated pathogen. J Immunol 2011;186:5406-12.
10. Shin SC, Kim SH, You H, et al. Drosophila microbiome modulates host developmental and metabolic homeostasis via insulin signaling. Science 2011;334:670-4.