Pharmacokinetics of natural borneol after oral administration in mice brain and its effect on excitation ratio

European Journal of Drug Metabolism and Pharmacokinetics

Volumn 37, Issue 1, 2012, Pages 39-44

  Li, Wei Rong ^a   Chen, Rui Yu ^a   Yang, Lei ^a   Huang, Tian Lai ^a   Xu, Qing Wen ^a   Mi, Sui Qing ^a   Wang, Ning Sheng ^a  

^a GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Aspartic acid; Gamma amino N butyric acid; Glutamic acid; Glycine; Natural borneol; Pharmacokinetics

Indexed keywords

4 AMINOBUTYRIC ACID; AMINO ACID; ASPARTIC ACID; BORNEOL; EXCITATORY AMINO ACID; GLUTAMIC ACID; GLYCINE; INHIBITORY AMINO ACID; NEUROTRANSMITTER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BRAIN REGION; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BRAIN LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG STRUCTURE; ENCEPHALE ISOLE; FEMALE; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; MOUSE; NEUROTOXICITY; NONHUMAN; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADMINISTRATION, ORAL; AMINO ACIDS; ANIMALS; BORNANES; BRAIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EXCITATORY AMINO ACIDS; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; MALE; MICE; NEUROTRANSMITTER AGENTS; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 84857654278     PISSN: 03787966     EISSN: 21070180     Source Type: Journal    
DOI: 10.1007/s13318-011-0058-5     Document Type: Article

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