Treatment of axillary hyperhidrosis with botulinum toxin: A single surgeon's experience with 53 consecutive patients

Aesthetic Plastic Surgery

Volumn 35, Issue 6, 2011, Pages 1079-1086

  Doft, Melissa A ^a   Kasten, Jennifer L ^b   Ascherman, Jeffrey A ^a  

^a NEW YORK PRESBYTERIAN HOSPITAL   (United States)

^b Columbia University College of Physicians and Surgeons ^*  (United States)

Author keywords

Axillary hyperhidrosis; Botox; Botulinum toxin

Indexed keywords

BOTULINUM TOXIN A; NEUROTOXIN;

ADULT; ARTICLE; AXILLA; CLINICAL TRIAL; FEMALE; HUMAN; HYPERHIDROSIS; MALE; PROSPECTIVE STUDY;

ADULT; AXILLA; BOTULINUM TOXINS, TYPE A; FEMALE; HUMANS; HYPERHIDROSIS; MALE; NEUROTOXINS; PROSPECTIVE STUDIES;

EID: 84857639550     PISSN: 0364216X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00266-011-9738-4     Document Type: Article

References (36)

1. Strutton DR, Kowalski JW, Glaser DA, Stang PE (2004) U.S. prevalence of hyperhidrosis and impact on individuals with axillary hyperhidrosis: results from a national survey. J Am Acad Dermatol 51:241-248
2. Naumann MK, Hamm H, Lowe NJ, on behalf of the Botox Hyperhidrosis Clinical Study Group (2002) Effect of botulinum toxin type A on quality-of-life measures in patients with excessive axillary sweating: a randomized controlled trial. Br J Der-matol 147:1218-1226 (Pubitemid 36963031)
3. Solish N, Benohanian A, Kowalski JW (2005) Prospective open-label study of botulinum toxin type A in patients with primary axillary hyperhidrosis: effects on functional impairment and quality of life. Dermatol Surg 31:405-413 (Pubitemid 40489300)
4. Swartling C, Naver H, Lindberg M (2001) Botulinum A toxin improves life quality in severe primary focal hyperhidrosis. Eur J Neurol 8:247-252 (Pubitemid 32476623)
5. Campanati A, Penna L, Guzzo T et al (2003) Quality-of-life assessment in patients with hyperhidrosis before and after treatment with botulinum toxin: results of an open-label study. Clin Ther 25:298-308 (Pubitemid 36206754)
6. Hornberger J, Grimes K, Naumann M, Glaser DA, Lowe NJ, Naver H et al (2004) Multi-specialty working group on the recognition, diagnosis, and treatment of primary focal hyperhidrosis: recognition, diagnosis, and treatment of primary focal hyperhi-drosis. J Am Acad Dermatol 51:274-286
7. Atkins JL, Butler PEM (2002) Hyperhidrosis: a review of current management. Plast Reconstr Surg 110:222-228 (Pubitemid 34686276)
8. Rompel R, Scholz S (2001) Subcutaneous curettage vs. injection of botulinum toxin A for treatment of axillary hyperhidrosis. J Eur Acad Dermatol Venereol 15:207-211 (Pubitemid 32898861)
9. Flanagan KH, King R, Glaser DA (2008) Botulinum toxin type A versus topical 20% aluminum chloride for the treatment of moderate to severe primary focal axillary hyperhidrosis. J Drugs Dermatol 7:221-227
10. Zacherl J, Huber ER, Imhof M et al (1998) Long-term results of 630 thoracoscopic sympathicotomies for primary hyperhidrosis: the Vienna experience. Eur J Surg Suppl 580:43-46 (Pubitemid 28215267)
11. Lin T, Wang N, Huang L (2001) Pitfalls and complication avoidance associated with transthoracic endoscopic sympathec-tomy for primary hyperhidrosis (analysis of 2,200 cases). Int J Surg Investig 2:377-385
12. Gossot D, Galetta D, Pascal A et al (2003) Long-term results of endoscopic thoracic sympathectomy for upper limb hyperhidro-sis. Ann Thorac Surg 75:1075-1079 (Pubitemid 36399378)
13. Arneja JS, Hayakawa TEJ, Singh GB et al (2007) Axillary hyperhidrosis: a 5-year review of treatment efficacy and recurrence rates using a new arthroscopic shaver technique. Plast Reconstr Surg 119:562-567 (Pubitemid 46142942)
14. Tung T (2001) Endoscopic shaver with liposuction for treatment of axillary osmidrosis. Ann Plast Surg 46:400-404 (Pubitemid 32319678)
15. Bushara KO, Park DM, Jones JC et al (1996) Botulinum toxin: a possible new treatment for axillary hyperhidrosis. Clin Exp Dermatol 21:276-278 (Pubitemid 26380193)
16. Glogau RG (1998) Botulinum A neurotoxin for axillary hyper-hidrosis: no sweat Botox. Dermatol Surg 24:817-819 (Pubitemid 28405012)
17. Naver H, Swartling C, Aquilonius SM (2000) Palmar and axillary hyperhidrosis treated with botulinum toxin: one-year clinical follow-up. Eur J Neurol 7:55-62 (Pubitemid 32268736)
18. Naumann M, Lowe NJ (2001) Botulinum toxin type A in treatment of bilateral primary axillary hyperhidrosis: randomized, parallel group, double-blind, placebo-controlled trial. BMJ 323:596-599 (Pubitemid 32846124)
19. Odderson IR (2002) Long-term quantitative benefits of botulinum toxin type A in the treatment of axillary hyperhidrosis. Dermatol Surg 28:480-483 (Pubitemid 34686631)
20. Heckmann M, Ceballos-Baumann AO, Plewig G (2001) Hyper-hidrosis Study Group: Botulinum toxin A for axillary hyperhi-drosis (excessive sweating). N Engl J Med 344:488-493
21. Lowe NJ, Glaser DE, Eadie N et al (2007) Botulinum toxin type A in the treatment of primary axillary hyperhidrosis: a 52-week multicenter double-blind, randomized, placebo-controlled study of efficacy and safety. J Am Acad Dermatol 56:604-611 (Pubitemid 46400197)
22. Heckmann M, Plewig G (2005) Low-dose efficacy of botulinum toxin A for axillary hyperhidrosis: a randomized, side-by-side, open-label study. Arch Dermatol 141:1255-1259 (Pubitemid 41498923)
23. Kowalski JW, Eadie N, Daggett S, et al (2004) Validity and Reliability of the Hyperhidrosis Disease Severity Scale (HDSS). Poster presented at the 62nd Annual Meeting of the American Academy of Dermatology, 6-10 February 2004, Washington, DC, Poster P198
24. R Development Core Team (2009) R: a language and environment for statistical computing. R Foundation for Statistical Computing: Vienna, Austria, 2009, ISBN 3-900051-07-0. http://www.R-project.org. Accessed June 2010
25. Wollina U, Karamfilov T, Konrad H (2002) High-dose botulinum toxin type A therapy for axillary hyperhidrosis markedly prolongs the relapse-free interval. J Am Acad Dermatol 46:536-540
26. Naumann M, Lowe NJ, Kumar CR et al (2003) Botulinum toxin type A is a safe and effective treatment for axillary hyperhidrosis over 16 months: a prospective study. Arch Dermatol 139:731-736 (Pubitemid 36705939)
27. Zuber M, Sebald M, Bathien N et al (1993) Botulinum antibodies in dystonic patients treated with type A botulinum toxin: frequency and significance. Neurology 43:1715-1718 (Pubitemid 23307942)
28. Jankovic J, Schwartz K (1995) Response and immunoresistance to botulinum toxin injections. Neurology 45:1743-1746
29. Moffat CE, Hayes WG, Nyamekye IK (2009) Durability of bot-ulinum toxin treatment for axillary hyperhidrosis. Eur J Vasc Endovasc Surg 38:188-191
30. Absar MS, Onwudike M (2008) Efficacy of botulinum toxin type A in the treatment of focal axillary hyperhidrosis. Dermatol Surg 34:751-755 (Pubitemid 351792285)
31. Hanlon L, Cahill R, Barry MC (2006) Prospective evaluation of the efficacy of dermal botulinum toxin for primary axillary hyperhidrosis. Irish J Med Sci 175:57-58
32. James R, Phillips D, Collin J (2005) Durability of botulinum toxin injection for axillary hyperhidrosis. Br J Surg 92:834-835 (Pubitemid 40961400)
33. Lowe PL, Cerdan-Sanz S, Lowe NJ (2003) Botulinum toxin type A in the treatment of bilateral primary axillary hyperhidrosis: efficacy and duration with repeated treatments. Dermatol Surg 29:545-548 (Pubitemid 36583156)
34. Schnider P, Moraru E, Kittler H et al (2001) Treatment of focal hyperhidrosis with botulinum toxin type A: long-term follow-up in 61 patients. Br J Dermatol 145:289-293 (Pubitemid 32955357)
35. Vadoud-Seyedi J, Simonart T (2007) Treatment of axillary hyperhidrosis with botulinum toxin type A reconstituted in lidocaine or in normal saline: a randomized, side-by-side, doubleblind study. Br J Dermatol 156:986-989 (Pubitemid 46642815)
36. Talarico-Filho S, Mendonça DO, Nascimento M et al (2007) A double-blind, randomized, comparative study of two type A botulinum toxins in the treatment of primary axillary hyperhyd-rosis. Dermatol Surg 33:S44-S50 (Pubitemid 46051399)