Topical nitrogen mustard therapy in patients with Langerhans cell histiocytosis

British Journal of Dermatology

Volumn 166, Issue 3, 2012, Pages 642-645

  Lindahl, L M ^a   Fenger Gron M ^b   Iversen, L ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; CHLORMETHINE; CYCLOPHOSPHAMIDE; ETRETIN; INTERFERON; METHOTREXATE; PREDNISOLONE; STEROID; VINBLASTINE; VINCRISTINE;

ADOLESCENT; ADULT; CHILD; CLINICAL ARTICLE; CONTACT DERMATITIS; DISEASE COURSE; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG SAFETY; DRUG TREATMENT FAILURE; FEMALE; GROUPS BY AGE; HISTIOCYTOSIS X; HUMAN; INFANT; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; RELAPSE; RETROSPECTIVE STUDY; REVIEW; SECOND CANCER; SKIN MANIFESTATION; TOPICAL TREATMENT; TREATMENT OUTCOME; TREATMENT RESPONSE;

ADMINISTRATION, CUTANEOUS; ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; DERMATITIS, IRRITANT; DERMATOLOGIC AGENTS; DRUG ADMINISTRATION SCHEDULE; DRUG ERUPTIONS; HISTIOCYTOSIS, LANGERHANS-CELL; HUMANS; INFANT; MECHLORETHAMINE; MIDDLE AGED; RETROSPECTIVE STUDIES; SKIN DISEASES; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84857636170     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2011.10673.x     Document Type: Review

References (11)

1. Goodfellow A, Cream JJ, Seed WA,. Histiocytosis X with unusual facial and axillary ulceration responding to topical nitrogen mustard. J R Soc Med 1982; 75: 279-81. (Pubitemid 12032264)
2. Salotti JA, Nanduri V, Pearce MS, et al. Incidence and clinical features of Langerhans cell histiocytosis in the UK and Ireland. Arch Dis Child 2009; 94: 376-80.
3. Weitzman S, Egeler RM,. Histiocytic disorders of children and adults: introduction to the problem, overview, historical perspective and epidemiology. In: Histiocytic Disorders of Children and Adults: Basic Science, Clinical Features and Therapy (, Weitzman S, Egeler RM, eds). Cambridge: Cambridge Books Online, Cambridge University Press, 2009; 1-13.
4. Margo CE, Goldman DR,. Langerhans cell histiocytosis. Surv Ophthalmol 2008; 53: 332-58. (Pubitemid 351902175)
5. Abla O, Egeler RM, Weitzman S,. Langerhans cell histiocytosis: current concepts and treatments. Cancer Treat Rev 2010; 36: 354-9.
6. Munn S, Chu AC,. Langerhans cell histiocytosis of the skin. Hematol Oncol Clin North Am 1998; 12: 269-86. (Pubitemid 28175880)
7. Hoeger PH, Nanduri VR, Harper JI, et al. Long term follow up of topical mustine treatment for cutaneous Langerhans cell histiocytosis. Arch Dis Child 2000; 82: 483-7. (Pubitemid 30367059)
8. Sheehan MP, Atherton DJ, Broadbent V, et al. Topical nitrogen mustard: an effective treatment for cutaneous Langerhans cell histiocytosis. J Pediatr 1991; 119: 317-21.
9. Nethercott JR, Murray AH, Medwidsky W, et al. Histiocytosis X in two adults. Treatment with topical mechlorethamine. Arch Dermatol 1983; 119: 157-61. (Pubitemid 13189217)
10. Kim YH, Martinez G, Varghese A, et al. Topical nitrogen mustard in the management of mycosis fungoides: update of the Stanford experience. Arch Dermatol 2003; 139: 165-73. (Pubitemid 36216254)
11. Vonderheid EC, Tan ET, Kantor AF, et al. Long-term efficacy, curative potential, and carcinogenicity of topical mechlorethamine chemotherapy in cutaneous T cell lymphoma. J Am Acad Dermatol 1989; 20: 416-28. (Pubitemid 19086776)