A prognostic gene expression profile that predicts circulating tumor cell presence in breast cancer patients

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Molloy, Timothy J ^a   Roepman, Paul ^b   Naume, Bjørn ^c   van't Veer, Laura J ^a,b  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b Agendia NV   (Netherlands)

^c OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; HORMONE; TUMOR MARKER;

ADULT; ARTICLE; BREAST CANCER; CANCER PATIENT; CIRCULATING TUMOR CELL; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE FREE SURVIVAL; GENE EXPRESSION PROFILING; GENETIC ANALYSIS; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MICROARRAY ANALYSIS; POLYMERASE CHAIN REACTION; PROGNOSIS; VALIDATION PROCESS; AGED; BIOLOGICAL MODEL; BLOOD; BREAST TUMOR; CELL PROLIFERATION; DNA MICROARRAY; FEMALE; GENE EXPRESSION REGULATION; METABOLISM; MIDDLE AGED; PATHOLOGY; REPRODUCIBILITY; TUMOR EMBOLISM;

ADULT; AGED; BREAST NEOPLASMS; CELL PROLIFERATION; COHORT STUDIES; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MIDDLE AGED; MODELS, GENETIC; NEOPLASTIC CELLS, CIRCULATING; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROGNOSIS; REPRODUCIBILITY OF RESULTS; TUMOR MARKERS, BIOLOGICAL;

EID: 84857603467     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032426     Document Type: Article

References (30)

1. Cristofanilli M, Budd GT, Ellis MJ, Stopeck A, Matera J, et al. (2004) Circulating tumor cells, disease progression, and survival in metastatic breast cancer. N Engl J Med 351: 781-791.
2. Molloy TJ, Devriese LA, Helgason HH, Bosma AJ, Hauptmann M, et al. (2011) A multimarker QPCR-based platform for the detection of circulating tumour cells in patients with early-stage breast cancer. British Journal of Cancer.
3. Weigelt B, Bosma AJ, Hart AA, Rodenhuis S, van 't Veer LJ, (2003) Marker genes for circulating tumour cells predict survival in metastasized breast cancer patients. Br J Cancer 88: 1091-1094.
4. Xenidis N, Ignatiadis M, Apostolaki S, Perraki M, Kalbakis K, et al. (2009) Cytokeratin-19 mRNA-positive circulating tumor cells after adjuvant chemotherapy in patients with early breast cancer. J Clin Oncol 27: 2177-2184.
5. Chang HY, Sneddon JB, Alizadeh AA, Sood R, West RB, et al. (2004) Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. PLoS Biol 2: E7.
6. Paik S, Shak S, Tang G, Kim C, Baker J, et al. (2004) A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. N Engl J Med 351: 2817-2826.
7. Sorlie T, Perou CM, Tibshirani R, Aas T, Geisler S, et al. (2001) Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A 98: 10869-10874.
8. van de Vijver MJ, He YD, van't Veer LJ, Dai H, Hart AA, et al. (2002) A gene-expression signature as a predictor of survival in breast cancer. N Engl J Med 347: 1999-2009.
9. van 't Veer LJ, Dai H, van de Vijver MJ, He YD, Hart AA, et al. (2002) Gene expression profiling predicts clinical outcome of breast cancer. Nature 415: 530-536.
10. Wang Y, Klijn JG, Zhang Y, Sieuwerts AM, Look MP, et al. (2005) Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer. Lancet 365: 671-679.
11. Wirapati P, Sotiriou C, Kunkel S, Farmer P, Pradervand S, et al. (2008) Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures. Breast Cancer Res 10: R65.
12. Fan C, Oh DS, Wessels L, Weigelt B, Nuyten DS, et al. (2006) Concordance among gene-expression-based predictors for breast cancer. N Engl J Med 355: 560-569.
13. McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, et al. (2006) REporting recommendations for tumor MARKer prognostic studies (REMARK). Breast cancer research and treatment 100: 229-235.
14. Brazma A, Hingamp P, Quackenbush J, Sherlock G, Spellman P, et al. (2001) Minimum information about a microarray experiment (MIAME)-toward standards for microarray data. Nature genetics 29: 365-371.
15. Naume B, Zhao X, Synnestvedt M, Borgen E, Russnes HG, et al. (2007) Presence of bone marrow micrometastasis is associated with different recurrencerisk within molecular subtypes of breast cancer. Mol Oncol 1: 160-171.
16. Molloy TJ, Bosma AJ, Baumbusch L, Synnestvedt M, Borgen E, et al. (2011) The prognostic significance of tumour cell detection in the peripheral blood versus the bone marrow in 733 early-stage breast cancer patients. Breast Cancer Research In press.
17. Wiedswang G, Borgen E, Karesen R, Kvalheim G, Nesland JM, et al. (2003) Detection of isolated tumor cells in bone marrow is an independent prognostic factor in breast cancer. J Clin Oncol 21: 3469-3478.
18. Glas AM, Floore A, Delahaye LJ, Witteveen AT, Pover RC, et al. (2006) Converting a breast cancer microarray signature into a high-throughput diagnostic test. BMC Genomics 7: 278.
19. Roepman P, Jassem J, Smit EF, Muley T, Niklinski J, et al. (2009) An immune response enriched 72-gene prognostic profile for early-stage non-small-cell lung cancer. Clin Cancer Res 15: 284-290.
20. Roepman P, Wessels LF, Kettelarij N, Kemmeren P, Miles AJ, et al. (2005) An expression profile for diagnosis of lymph node metastases from primary head and neck squamous cell carcinomas. Nat Genet 37: 182-186.
21. Wiedswang G, Borgen E, Schirmer C, Karesen R, Kvalheim G, et al. (2006) Comparison of the clinical significance of occult tumor cells in blood and bone marrow in breast cancer. Int J Cancer 118: 2013-2019.
22. Braun S, Vogl FD, Naume B, Janni W, Osborne MP, et al. (2005) A pooled analysis of bone marrow micrometastasis in breast cancer. N Engl J Med 353: 793-802.
23. Lyman GH, Giuliano AE, Somerfield MR, Benson AB 3rd, Bodurka DC, et al. (2005) American Society of Clinical Oncology guideline recommendations for sentinel lymph node biopsy in early-stage breast cancer. J Clin Oncol 23: 7703-7720.
24. Molloy TJ, Bosma AJ, van't Veer LJ, (2008) Towards an optimized platform for the detection, enrichment, and semi-quantitation circulating tumor cells. Breast Cancer Res Treat 112: 297-307.
25. Chang HY, Nuyten DS, Sneddon JB, Hastie T, Tibshirani R, et al. (2005) Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival. Proc Natl Acad Sci U S A 102: 3738-3743.
26. Sorlie T, Tibshirani R, Parker J, Hastie T, Marron JS, et al. (2003) Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci U S A 100: 8418-8423.
27. Ma XJ, Wang Z, Ryan PD, Isakoff SJ, Barmettler A, et al. (2004) A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen. Cancer Cell 5: 607-616.
28. Wikman H, Vessella R, Pantel K, (2008) Cancer micrometastasis and tumour dormancy. APMIS 116: 754-770.
29. Reyal F, Valet F, de Cremoux P, Mathiot C, Decraene C, et al. (2011) Circulating tumor cell detection and transcriptomic profiles in early breast cancer patients. Annals of oncology: official journal of the European Society for Medical Oncology/ESMO 22: 1458-1459.
30. Bosma AJ, Weigelt B, Lambrechts AC, Verhagen OJ, Pruntel R, et al. (2002) Detection of circulating breast tumor cells by differential expression of marker genes. Clin Cancer Res 8: 1871-1877.