Lineage-specific virulence determinants of Haemophilus influenzae biogroup aegyptius

Emerging Infectious Diseases

Volumn 18, Issue 3, 2012, Pages 449-457

  Strouts, Fiona R ^a,e   Power, Peter ^b   Croucher, Nicholas J ^c   Corton, Nicola ^c   van Tonder, Andries ^c   Quail, Michael A ^c   Langford, Paul R ^a   Hudson, Michael J ^d   Parkhill, Julian ^c   Kroll, J Simon ^a   Bentley, Stephen D ^c  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^d PUBLIC HEALTH ENGLAND   (United Kingdom)

^e STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN;

ARTICLE; BACTERIAL GENOME; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CLONE; CONTROLLED STUDY; FIMBRIA; GENE SEQUENCE; GENOME ANALYSIS; HAEMOPHILUS INFLUENZAE; HAEMOPHILUS INFLUENZAE BIOGROUP AEGYPTIUS; NONHUMAN; NUCLEOTIDE SEQUENCE; OPERON;

ADHESINS, BACTERIAL; GENE ORDER; GENOME, BACTERIAL; HAEMOPHILUS INFECTIONS; HAEMOPHILUS INFLUENZAE; HOST-PATHOGEN INTERACTIONS; HUMANS; MOLECULAR SEQUENCE ANNOTATION; MOLECULAR SEQUENCE DATA; OPERON; PHYLOGENY; SEQUENCE HOMOLOGY; VIRULENCE; VIRULENCE FACTORS;

EID: 84857585567     PISSN: 10806040     EISSN: 10806059     Source Type: Journal    
DOI: 10.3201/eid1803.110728     Document Type: Article

References (40)

1. Koch R. Report on activities of the German Cholera Commission in Egypt and East India [in German]. Wien Med Wochenschr. 1883;1548-51.
2. Weeks JN. The bacillus of acute catarrhal conjunctivitis. Arch Ophthalmol. 1886;15:441-51.
3. Harrison LH, da Silva GA, Pittman M, Fleming DW, Vranjac A, Broome CV. Epidemiology and clinical spectrum of Brazilian purpuric fever. Brazilian Purpuric Fever Study Group. J Clin Microbiol. 1989;27:599-604.
4. McIntyre P, Wheaton G, Erlich J, Hansman D. Brasilian purpuric fever in central Australia. Lancet. 1987;330:112. http://dx.doi.org/10.1016/S0140-6736(87)92788-7
5. Virata M, Rosenstein NE, Hadler JL, Barrett NL, Tondella ML, Mayer LW, et al. Suspected Brazilian purpuric fever in a toddler with overwhelming Epstein-Barr virus infection. Clin Infect Dis. 1998;27:1238-40. http://dx.doi.org/10.1086/514988
6. Harrison LH, Simonsen V, Waldman EA. Emergence and disappearance of a virulent clone of Haemophilus influenzae biogroup aegyptius, cause of Brazilian purpuric fever. Clin Microbiol Rev. 2008;21:594-605. http://dx.doi.org/10.1128/CMR.00020-08
7. Santana-Porto EA, Oliveira AA, da Costa MRM, Pinheiro AS, Oliveira C, Lopes ML, et al. Suspected Brazilian purpuric fever, Brazilian Amazon region. Emerg Infect Dis. 2009;15:675-6. http://dx.doi.org/10.3201/eid1504.090014
8. Erwin AL, Sandstedt SA, Bonthuis PJ, Geelhood JL, Nelson KL, Unrath WC, et al. Analysis of genetic relatedness of Haemophilus influenzae isolates by multilocus sequence typing. J Bacteriol. 2008;190:1473-83. http://dx.doi.org/10.1128/JB.01207-07
9. Rubin LG, Gloster ES, Carlone GM. An infant rat model of bacteremia with Brazilian purpuric fever isolates of Hemophilus influenzae biogroup aegyptius. Brazilian Purpuric Fever Study Group. J Infect Dis. 1989;160:476-82. http://dx.doi.org/10.1093/infdis/160.3.476
10. Weyant RS, Quinn FD, Utt EA, Worley M, George VG, Candal FJ, et al. Human microvascular endothelial cell toxicity caused by Brazilian purpuric fever-associated strains of Haemophilus influenzae biogroup aegyptius. J Infect Dis. 1994;169:430-3. http://dx.doi.org/10.1093/infdis/169.2.430
11. Rubin LG, Peters VB, Ferez MC. Bactericidal activity of human sera against a Brazilian purpuric fever (BPF) strain of Haemophilus influenzae biogroup aegyptius correlates with age-related occurrence of BPF. J Infect Dis. 1993;167:1262-4. http://dx.doi.org/10.1093/infdis/167.5.1262
12. Erwin AL, Munford RS. Comparison of lipopolysaccharides from Brazilian purpuric fever isolates and conjunctivitis isolates of Haemophilus influenzae biogroup aegyptius. Brazilian Purpuric Fever Study Group. J Clin Microbiol. 1989;27:762-7.
13. Farley MM, Whitney AM, Spellman P, Quinn FD, Weyant RS, Mayer L, et al. Analysis of the attachment and invasion of human epithelial cells by Haemophilus influenzae biogroup aegyptius. J Infect Dis. 1992;165(Suppl 1):S111-4. http://dx.doi.org/10.1093/infdis/165-Supplement_1-S111
14. Barbosa SF, Hoshino-Shimizu S, Alkmin MG, Goto H. Implications of Haemophilus influenzae biogroup aegyptius hemagglutinins in the pathogenesis of Brazilian purpuric fever. J Infect Dis. 2003;188:74-80. http://dx.doi.org/10.1086/375739
15. Rubin LG. Role of the 145-kilodalton surface protein in virulence of the Brazilian purpuric fever clone of Haemophilus influenzae biogroup aegyptius for infant rats. Infect Immun. 1995;63:3555-8.
16. Dobson SR, Kroll JS, Moxon ER. Insertion sequence IS1016 and absence of Haemophilus capsulation genes in the Brazilian purpuric fever clone of Haemophilus influenzae biogroup aegyptius. Infect Immun. 1992;60:618-22.
17. Karlsson E, Melhus A. Nontypeable Haemophilus influenzae strains with the capsule-associated insertion element IS1016 may mimic encapsulated strains. APMIS. 2006;114:633-40. http://dx.doi.org/10.1111/j.1600-0463.2006.apm_333.x
18. Satola SW, Napier B, Farley MM. Association of IS1016 with the hia adhesin gene and biotypes V and I in invasive nontypeable Haemophilus influenzae. Infect Immun. 2008;76:5221-7. http://dx.doi.org/10.1128/IAI.00672-08
19. Hogg JS, Hu FZ, Janto B, Boissy R, Hayes J, Keefe R, et al. Characterization and modeling of the Haemophilus influenzae core and supragenomes based on the complete genomic sequences of Rd and 12 clinical nontypeable strains. Genome Biol. 2007;8:R103. http://dx.doi.org/10.1186/gb-2007-8-6-r103
20. Barenkamp SJ, Leininger E. Cloning, expression, and DNA sequence analysis of genes encoding nontypeable Haemophilus influenzae high-molecular-weight surface-exposed proteins related to filamentous hemagglutinin of Bordetella pertussis. Infect Immun. 1992;60:1302-13.
21. Brenner DJ, Mayer LW, Carlone GM, Harrison LH, Bibb WF, Brandileone MC, et al. Biochemical, genetic, and epidemiologic characterization of Haemophilus influenzae biogroup aegyptius (Haemophilus aegyptius) strains associated with Brazilian purpuric fever. J Clin Microbiol. 1988;26:1524-34.
22. Carver T, Berriman M, Tivey A, Patel C, Böhme U, Barrell BG, et al. Artemis and ACT: viewing, annotating and comparing sequences stored in a relational database. Bioinformatics. 2008;24:2672-6. http://dx.doi.org/10.1093/bioinformatics/btn529
23. Lowe TM, Eddy SR. tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence. Nucleic Acids Res. 1997;25:955-64. http://dx.doi.org/10.1093/nar/25.5.955
24. Darling AC, Mau B, Blattner FR, Perna NT. MAUVE: multiple alignment of conserved genomic sequence with rearrangements. Genome Res. 2004;14:1394-403. http://dx.doi.org/10.1101/gr.2289704
25. Tamura K, Peterson D, Peterson N, Stecher G, Nei M, Kumar S. MEGA5: Molecular Evolutionary Genetics Analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol Biol Evol. 2011;28:2731-9. http://dx.doi.org/10.1093/molbev/msr121
26. Kroll JS, Farrant JL, Tyler S, Coulthart MB, Langford PR. Characterisation and genetic organisation of a 24-MDa plasmid from the Brazilian purpuric fever clone of Haemophilus influenzae biogroup aegyptius. Plasmid. 2002;48:38-48. http://dx.doi.org/10.1016/S0147-619X(02)00020-3
27. Read TD, Dowdell M, Satola SW, Farley MM. Duplication of pilus gene complexes of Haemophilus influenzae biogroup aegyptius. J Bacteriol. 1996;178:6564-70.
28. Kilian M, Poulsen K, Lomholt H. Evolution of the paralogous hap and iga genes in Haemophilus influenzae: evidence for a conserved hap pseudogene associated with microcolony formation in the recently diverged Haemophilus aegyptius and H. influenzae biogroup aegyptius. Mol Microbiol. 2002;46:1367-80. http://dx.doi.org/10.1046/j.1365-2958.2002.03254.x
29. St Geme JW III, Falkow S, Barenkamp SJ. High-molecular-weight proteins of nontypeable Haemophilus influenzae mediate attachment to human epithelial cells. Proc Natl Acad Sci USA. 1993;90:2875-9. http://dx.doi.org/10.1073/pnas.90.7.2875
30. Giufrè M, Muscillo M, Spigaglia P, Cardines R, Mastrantonio P, Cerquetti M. Conservation and diversity of HMW1 and HMW2 adhesin binding domains among invasive nontypeable Haemophilus influenzae isolates. Infect Immun. 2006;74:1161-70. http://dx.doi.org/10.1128/IAI.74.2.1161-1170.2006
31. Dawid S, Barenkamp SJ, St Geme JW III. Variation in expression of the Haemophilus influenzae HMW adhesins: a prokaryotic system reminiscent of eukaryotes. Proc Natl Acad Sci USA. 1999;96:1077-82. http://dx.doi.org/10.1073/pnas.96.3.1077
32. Power PM, Sweetman WA, Gallacher NJ, Woodhall MR, Kumar GA, Moxon ER, et al. Simple sequence repeats in Haemophilus influenzae. Infect Genet Evol. 2009;9:216-28. http://dx.doi.org/10.1016/j.meegid.2008.11.006
33. St Geme JW III, Cutter D, Barenkamp SJ. Characterization of the genetic locus encoding Haemophilus influenzae type b surface fibrils. J Bacteriol. 1996;178:6281-7.
34. Barenkamp SJ, St Geme JW III. Identification of a second family of high-molecular-weight adhesion proteins expressed by non-typeable Haemophilus influenzae. Mol Microbiol. 1996;19:1215-23. http://dx.doi.org/10.1111/j.1365-2958.1996.tb02467.x
35. Sheets AJ, Grass SA, Miller SE, St Geme JW III. Identification of a novel trimeric autotransporter adhesin in the cryptic genospecies of Haemophilus. J Bacteriol. 2008;190:4313-20. http://dx.doi.org/10.1128/JB.01963-07
36. Serruto D, Spadafina T, Scarselli M, Bambini S, Comanducci M, Höhle S, et al. HadA is an atypical new multifunctional trimeric coiled-coil adhesin of Haemophilus influenzae biogroup aegyptius, which promotes entry into host cells. Cell Microbiol. 2009;11:1044-63. http://dx.doi.org/10.1111/j.1462-5822.2009.01306.x
37. Mota LJ, Journet L, Sorg I, Agrain C, Cornelis GR. Bacterial injectisomes: needle length does matter. Science. 2005;307:1278. http://dx.doi.org/10.1126/science.1107679
38. Williams BJ, Golomb M, Phillips T, Brownlee J, Olson MV, Smith AL. Bacteriophage HP2 of Haemophilus influenzae. J Bacteriol. 2002;184:6893-905. http://dx.doi.org/10.1128/JB.184.24.6893-6905.2002
39. St Geme JW III, Gilsdorf JR, Falkow S. Surface structures and adherence properties of diverse strains of Haemophilus influenzae biogroup aegyptius. Infect Immun. 1991;59:3366-71.
40. Smoot LM, Bell EC, Crosa JH, Actis LA. Fur and iron transport binding proteins in the Brazilian purpuric fever clone of Haemophilus influenzae biogroup aegyptius. J Med Microbiol. 1999;48:629-36. http://dx.doi.org/10.1099/00222615-48-7-629