메뉴 건너뛰기




Volumn 22, Issue 2, 2012, Pages 108-118

Predicting Recurrence After Radiotherapy in Head and Neck Cancer

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; CARBONATE DEHYDRATASE IX; EPIDERMAL GROWTH FACTOR RECEPTOR; HERMES ANTIGEN; HYPOXIA INDUCIBLE FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1BETA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; MESSENGER RNA; MICRORNA; PROTEIN VP16;

EID: 84857553659     PISSN: 10534296     EISSN: 15329461     Source Type: Journal    
DOI: 10.1016/j.semradonc.2011.12.002     Document Type: Review
Times cited : (63)

References (106)
  • 1
    • 33646568784 scopus 로고    scopus 로고
    • Patterns of cancer incidence, mortality, and prevalence across five continents: Defining priorities to reduce cancer disparities in different geographic regions of the world
    • Kamangar F., Dores G.M., Anderson W.F. Patterns of cancer incidence, mortality, and prevalence across five continents: Defining priorities to reduce cancer disparities in different geographic regions of the world. J Clin Oncol 2006, 24:2137-2150.
    • (2006) J Clin Oncol , vol.24 , pp. 2137-2150
    • Kamangar, F.1    Dores, G.M.2    Anderson, W.F.3
  • 2
    • 0034960064 scopus 로고    scopus 로고
    • A comparison of published head and neck stage groupings in carcinomas of the oral cavity
    • Groome P.A., Schulze K., Boysen M., et al. A comparison of published head and neck stage groupings in carcinomas of the oral cavity. Head Neck 2001, 23:613-624.
    • (2001) Head Neck , vol.23 , pp. 613-624
    • Groome, P.A.1    Schulze, K.2    Boysen, M.3
  • 3
    • 0036281276 scopus 로고    scopus 로고
    • A comparison of published head and neck stage groupings in laryngeal cancer using data from two countries
    • Groome P.A., Schulze K., Boysen M., et al. A comparison of published head and neck stage groupings in laryngeal cancer using data from two countries. J Clin Epidemiol 2002, 55:533-544.
    • (2002) J Clin Epidemiol , vol.55 , pp. 533-544
    • Groome, P.A.1    Schulze, K.2    Boysen, M.3
  • 4
    • 0031858774 scopus 로고    scopus 로고
    • Tumor volume: A basic and specific response predictor in radiotherapy
    • Dubben H.H., Thames H.D., Beck-Bornholdt H.P. Tumor volume: A basic and specific response predictor in radiotherapy. Radiother Oncol 1998, 47:167-174.
    • (1998) Radiother Oncol , vol.47 , pp. 167-174
    • Dubben, H.H.1    Thames, H.D.2    Beck-Bornholdt, H.P.3
  • 5
    • 0033988037 scopus 로고    scopus 로고
    • The impact of primary tumor volume on local control for oropharyngeal squamous cell carcinoma treated with radiotherapy
    • Nathu R.M., Mancuso A.A., Zhu T.C., et al. The impact of primary tumor volume on local control for oropharyngeal squamous cell carcinoma treated with radiotherapy. Head Neck 2000, 22:1-5.
    • (2000) Head Neck , vol.22 , pp. 1-5
    • Nathu, R.M.1    Mancuso, A.A.2    Zhu, T.C.3
  • 6
    • 4744355864 scopus 로고    scopus 로고
    • Pretreatment probability model for predicting outcome after intraarterial chemoradiation for advanced head and neck carcinoma
    • van den Broek G.B., Rasch C.R., Pameijer F.A., et al. Pretreatment probability model for predicting outcome after intraarterial chemoradiation for advanced head and neck carcinoma. Cancer 2004, 101:1809-1817.
    • (2004) Cancer , vol.101 , pp. 1809-1817
    • van den Broek, G.B.1    Rasch, C.R.2    Pameijer, F.A.3
  • 7
    • 0033621687 scopus 로고    scopus 로고
    • Tumor radiosensitivity (SF2) is a prognostic factor for local control in head and neck cancers
    • Björk-Eriksson T., West C., Karlsson E., et al. Tumor radiosensitivity (SF2) is a prognostic factor for local control in head and neck cancers. Int J Radiat Oncol Biol Phys 2000, 46:13-19.
    • (2000) Int J Radiat Oncol Biol Phys , vol.46 , pp. 13-19
    • Björk-Eriksson, T.1    West, C.2    Karlsson, E.3
  • 8
    • 0034307112 scopus 로고    scopus 로고
    • A confirmatory prognostic study on oxygenation status and loco-regional control in advanced head and neck squamous cell carcinoma treated by radiation therapy
    • Nordsmark M., Overgaard J. A confirmatory prognostic study on oxygenation status and loco-regional control in advanced head and neck squamous cell carcinoma treated by radiation therapy. Radiother Oncol 2000, 57:39-43.
    • (2000) Radiother Oncol , vol.57 , pp. 39-43
    • Nordsmark, M.1    Overgaard, J.2
  • 9
    • 21844455567 scopus 로고    scopus 로고
    • Hypoxia in head and neck cancer: How much, how important?
    • Janssen H.L., Haustermans K.M., Balm A.J., et al. Hypoxia in head and neck cancer: How much, how important?. Head Neck 2005, 27:622-638.
    • (2005) Head Neck , vol.27 , pp. 622-638
    • Janssen, H.L.1    Haustermans, K.M.2    Balm, A.J.3
  • 10
    • 0023894783 scopus 로고
    • The hazard of accelerated tumor clonogen repopulation during radiotherapy
    • Withers H.R., Taylor J.M., Maciejewski B. The hazard of accelerated tumor clonogen repopulation during radiotherapy. Acta Oncol 1988, 27:131-146.
    • (1988) Acta Oncol , vol.27 , pp. 131-146
    • Withers, H.R.1    Taylor, J.M.2    Maciejewski, B.3
  • 11
    • 21744437791 scopus 로고    scopus 로고
    • Repopulation of cancer cells during therapy: An important cause of treatment failure
    • Kim J.J., Tannock I.F. Repopulation of cancer cells during therapy: An important cause of treatment failure. Nat Rev Cancer 2005, 5:516-525.
    • (2005) Nat Rev Cancer , vol.5 , pp. 516-525
    • Kim, J.J.1    Tannock, I.F.2
  • 13
    • 67349150659 scopus 로고    scopus 로고
    • Current concepts of management in radiotherapy for head and neck squamous-cell cancer
    • Mazeron R., Tao Y., Lusinchi A., et al. Current concepts of management in radiotherapy for head and neck squamous-cell cancer. Oral Oncol 2009, 45:402-408.
    • (2009) Oral Oncol , vol.45 , pp. 402-408
    • Mazeron, R.1    Tao, Y.2    Lusinchi, A.3
  • 14
    • 32144433159 scopus 로고    scopus 로고
    • Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
    • Bonner J.A., Harari P.M., Giralt J., et al. Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 2006, 354:567-578.
    • (2006) N Engl J Med , vol.354 , pp. 567-578
    • Bonner, J.A.1    Harari, P.M.2    Giralt, J.3
  • 15
    • 79953054421 scopus 로고    scopus 로고
    • Strategies to improve radiotherapy with targeted drugs
    • Begg A.C., Stewart F.A., Vens C. Strategies to improve radiotherapy with targeted drugs. Nat Rev Cancer 2011, 11:239-253.
    • (2011) Nat Rev Cancer , vol.11 , pp. 239-253
    • Begg, A.C.1    Stewart, F.A.2    Vens, C.3
  • 16
    • 36248962105 scopus 로고    scopus 로고
    • The genomic landscapes of human breast and colorectal cancers
    • Wood L.D., Parsons D.W., Jones S., et al. The genomic landscapes of human breast and colorectal cancers. Science 2007, 318:1108-1113.
    • (2007) Science , vol.318 , pp. 1108-1113
    • Wood, L.D.1    Parsons, D.W.2    Jones, S.3
  • 17
    • 85027927831 scopus 로고    scopus 로고
    • High-resolution characterization of a hepatocellular carcinoma genome
    • Totoki Y., Tatsuno K., Yamamoto S., et al. High-resolution characterization of a hepatocellular carcinoma genome. Nat Genet 2011, 43:464-469.
    • (2011) Nat Genet , vol.43 , pp. 464-469
    • Totoki, Y.1    Tatsuno, K.2    Yamamoto, S.3
  • 18
    • 17244373777 scopus 로고    scopus 로고
    • Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
    • Farmer H., McCabe N., Lord C.J., et al. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature 2005, 434:917-921.
    • (2005) Nature , vol.434 , pp. 917-921
    • Farmer, H.1    McCabe, N.2    Lord, C.J.3
  • 19
    • 17244375049 scopus 로고    scopus 로고
    • Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
    • Bryant H.E., Schultz N., Thomas H.D., et al. Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase. Nature 2005, 434:913-917.
    • (2005) Nature , vol.434 , pp. 913-917
    • Bryant, H.E.1    Schultz, N.2    Thomas, H.D.3
  • 20
    • 67650471685 scopus 로고    scopus 로고
    • Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers
    • Fong P.C., Boss D.S., Yap T.A., et al. Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers. N Engl J Med 2009, 361:123-134.
    • (2009) N Engl J Med , vol.361 , pp. 123-134
    • Fong, P.C.1    Boss, D.S.2    Yap, T.A.3
  • 21
    • 0027379128 scopus 로고
    • Intrinsic radiosensitivity and prediction of patient response to radiotherapy for carcinoma of the cervix
    • West C.M., Davidson S.E., Roberts S.A., et al. Intrinsic radiosensitivity and prediction of patient response to radiotherapy for carcinoma of the cervix. Br J Cancer 1993, 68:819-823.
    • (1993) Br J Cancer , vol.68 , pp. 819-823
    • West, C.M.1    Davidson, S.E.2    Roberts, S.A.3
  • 22
    • 70350062591 scopus 로고    scopus 로고
    • Predicting response to radiotherapy: Evolutions and revolutions
    • Begg A.C. Predicting response to radiotherapy: Evolutions and revolutions. Int J Radiat Biol 2009, 85:825-836.
    • (2009) Int J Radiat Biol , vol.85 , pp. 825-836
    • Begg, A.C.1
  • 23
    • 39149090682 scopus 로고    scopus 로고
    • CGH microarrays and cancer
    • Kallioniemi A. CGH microarrays and cancer. Curr Opin Biotechnol 2008, 19:36-40.
    • (2008) Curr Opin Biotechnol , vol.19 , pp. 36-40
    • Kallioniemi, A.1
  • 24
    • 0033868920 scopus 로고    scopus 로고
    • Genome-wide screening for radiation response factors in head and neck cancer
    • Singh B., Kim S.H., Carew J.F., et al. Genome-wide screening for radiation response factors in head and neck cancer. Laryngoscope 2000, 110:1251-1256.
    • (2000) Laryngoscope , vol.110 , pp. 1251-1256
    • Singh, B.1    Kim, S.H.2    Carew, J.F.3
  • 25
    • 34547663365 scopus 로고    scopus 로고
    • Genetic abnormalities associated with chemoradiation resistance of head and neck squamous cell carcinoma
    • van den Broek G.B., Wreesmann V.B., Van den Brekel M.W., et al. Genetic abnormalities associated with chemoradiation resistance of head and neck squamous cell carcinoma. Clin Cancer Res 2007, 13:4386-4391.
    • (2007) Clin Cancer Res , vol.13 , pp. 4386-4391
    • van den Broek, G.B.1    Wreesmann, V.B.2    Van den Brekel, M.W.3
  • 26
    • 80655127835 scopus 로고    scopus 로고
    • Retention of gammaH2AX foci as an indication of lethal DNA damage
    • Olive P.L. Retention of gammaH2AX foci as an indication of lethal DNA damage. Radiother Oncol 2011, 101:18-23.
    • (2011) Radiother Oncol , vol.101 , pp. 18-23
    • Olive, P.L.1
  • 27
    • 74549209655 scopus 로고    scopus 로고
    • Endogenous and radiation-induced expression of gammaH2AX in biopsies from patients treated for carcinoma of the uterine cervix
    • Olive P.L., Banuelos C.A., Durand R.E., et al. Endogenous and radiation-induced expression of gammaH2AX in biopsies from patients treated for carcinoma of the uterine cervix. Radiother Oncol 2010, 94:82-89.
    • (2010) Radiother Oncol , vol.94 , pp. 82-89
    • Olive, P.L.1    Banuelos, C.A.2    Durand, R.E.3
  • 28
    • 80051783228 scopus 로고    scopus 로고
    • Residual DNA double strand breaks in perfused but not in unperfused areas determine different radiosensitivity of tumours
    • Menegakis A., Eicheler W., Yaromina A., et al. Residual DNA double strand breaks in perfused but not in unperfused areas determine different radiosensitivity of tumours. Radiother Oncol 2011, 100:137-144.
    • (2011) Radiother Oncol , vol.100 , pp. 137-144
    • Menegakis, A.1    Eicheler, W.2    Yaromina, A.3
  • 29
    • 23844439529 scopus 로고    scopus 로고
    • Prediction of radiation sensitivity using a gene expression classifier
    • Torres-Roca J.F., Eschrich S., Zhao H., et al. Prediction of radiation sensitivity using a gene expression classifier. Cancer Res 2005, 65:7169-7176.
    • (2005) Cancer Res , vol.65 , pp. 7169-7176
    • Torres-Roca, J.F.1    Eschrich, S.2    Zhao, H.3
  • 30
    • 39049106219 scopus 로고    scopus 로고
    • Integrating global gene expression and radiation survival parameters across the 60 cell lines of the National Cancer Institute Anticancer Drug Screen
    • Amundson S.A., Do K.T., Vinikoor L.C., et al. Integrating global gene expression and radiation survival parameters across the 60 cell lines of the National Cancer Institute Anticancer Drug Screen. Cancer Res 2008, 68:415-424.
    • (2008) Cancer Res , vol.68 , pp. 415-424
    • Amundson, S.A.1    Do, K.T.2    Vinikoor, L.C.3
  • 31
    • 36149001337 scopus 로고    scopus 로고
    • Gene expression profiling to predict outcome after chemoradiation in head and neck cancer
    • Pramana J., Van den Brekel M.W., van Velthuysen M.L., et al. Gene expression profiling to predict outcome after chemoradiation in head and neck cancer. Int J Radiat Oncol Biol Phys 2007, 69:1544-1552.
    • (2007) Int J Radiat Oncol Biol Phys , vol.69 , pp. 1544-1552
    • Pramana, J.1    Van den Brekel, M.W.2    van Velthuysen, M.L.3
  • 32
    • 69549116364 scopus 로고    scopus 로고
    • A gene expression model of intrinsic tumor radiosensitivity: Prediction of response and prognosis after chemoradiation
    • Eschrich S.A., Pramana J., Zhang H., et al. A gene expression model of intrinsic tumor radiosensitivity: Prediction of response and prognosis after chemoradiation. Int J Radiat Oncol Biol Phys 2009, 75:489-496.
    • (2009) Int J Radiat Oncol Biol Phys , vol.75 , pp. 489-496
    • Eschrich, S.A.1    Pramana, J.2    Zhang, H.3
  • 33
    • 78049452311 scopus 로고    scopus 로고
    • CD44 expression predicts local recurrence after radiotherapy in larynx cancer
    • de Jong M.C., Pramana J., van der Wal J.E., et al. CD44 expression predicts local recurrence after radiotherapy in larynx cancer. Clin Cancer Res 2010, 16:5329-5338.
    • (2010) Clin Cancer Res , vol.16 , pp. 5329-5338
    • de Jong, M.C.1    Pramana, J.2    van der Wal, J.E.3
  • 34
    • 79957568722 scopus 로고    scopus 로고
    • Promoter methylation in head and neck squamous cell carcinoma cell lines is significantly different than methylation in primary tumors and xenografts
    • Hennessey P.T., Ochs M.F., Mydlarz W.W., et al. Promoter methylation in head and neck squamous cell carcinoma cell lines is significantly different than methylation in primary tumors and xenografts. PLoS ONE 2011, 6:e20584.
    • (2011) PLoS ONE , vol.6
    • Hennessey, P.T.1    Ochs, M.F.2    Mydlarz, W.W.3
  • 35
    • 0027339592 scopus 로고
    • Intratumoral pO2 predicts survival in advanced cancer of the uterine cervix
    • Höckel M., Knoop C., Schlenger K., et al. Intratumoral pO2 predicts survival in advanced cancer of the uterine cervix. Radiother Oncol 1993, 26:45-50.
    • (1993) Radiother Oncol , vol.26 , pp. 45-50
    • Höckel, M.1    Knoop, C.2    Schlenger, K.3
  • 36
    • 0034743861 scopus 로고    scopus 로고
    • Oxygen status of malignant tumors: Pathogenesis of hypoxia and significance for tumor therapy
    • Vaupel P., Kelleher D.K., Hockel M. Oxygen status of malignant tumors: Pathogenesis of hypoxia and significance for tumor therapy. Semin Oncol 2001, 28:29-35.
    • (2001) Semin Oncol , vol.28 , pp. 29-35
    • Vaupel, P.1    Kelleher, D.K.2    Hockel, M.3
  • 37
    • 0030025773 scopus 로고    scopus 로고
    • Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
    • Graeber T.G., Osmanian C., Jacks T., et al. Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours. Nature 1996, 379:88-91.
    • (1996) Nature , vol.379 , pp. 88-91
    • Graeber, T.G.1    Osmanian, C.2    Jacks, T.3
  • 38
    • 1542405875 scopus 로고    scopus 로고
    • Acute hypoxia enhances spontaneous lymph node metastasis in an orthotopic murine model of human cervical carcinoma
    • Cairns R.A., Hill R.P. Acute hypoxia enhances spontaneous lymph node metastasis in an orthotopic murine model of human cervical carcinoma. Cancer Res 2004, 64:2054-2061.
    • (2004) Cancer Res , vol.64 , pp. 2054-2061
    • Cairns, R.A.1    Hill, R.P.2
  • 39
    • 0030742027 scopus 로고    scopus 로고
    • Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck
    • Brizel D.M., Sibley G.S., Prosnitz L.R., et al. Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck. Int J Radiat Oncol Biol Phys 1997, 38:285-289.
    • (1997) Int J Radiat Oncol Biol Phys , vol.38 , pp. 285-289
    • Brizel, D.M.1    Sibley, G.S.2    Prosnitz, L.R.3
  • 40
    • 33644551073 scopus 로고    scopus 로고
    • Gene expression programs in response to hypoxia: Cell type specificity and prognostic significance in human cancers
    • Chi J.T., Wang Z., Nuyten D.S., et al. Gene expression programs in response to hypoxia: Cell type specificity and prognostic significance in human cancers. PLoS Med 2006, 3:e47.
    • (2006) PLoS Med , vol.3
    • Chi, J.T.1    Wang, Z.2    Nuyten, D.S.3
  • 41
    • 77955364492 scopus 로고    scopus 로고
    • Identification of multiple hypoxia signatures in neuroblastoma cell lines by l1-L2 regularization and data reduction
    • Fardin P., Cornero A., Barla A., et al. Identification of multiple hypoxia signatures in neuroblastoma cell lines by l1-L2 regularization and data reduction. J Biomed Biotechnol 2010, 2010:878709.
    • (2010) J Biomed Biotechnol , vol.2010 , pp. 878709
    • Fardin, P.1    Cornero, A.2    Barla, A.3
  • 42
    • 34248172298 scopus 로고    scopus 로고
    • Relation of a hypoxia metagene derived from head and neck cancer to prognosis of multiple cancers
    • Winter S.C., Buffa F.M., Silva P., et al. Relation of a hypoxia metagene derived from head and neck cancer to prognosis of multiple cancers. Cancer Res 2007, 67:3441-3449.
    • (2007) Cancer Res , vol.67 , pp. 3441-3449
    • Winter, S.C.1    Buffa, F.M.2    Silva, P.3
  • 43
    • 75149177193 scopus 로고    scopus 로고
    • LIN28B confers radio-resistance through the posttranscriptional control of KRAS
    • Jeong S.H., Wu H.G., Park W.Y. LIN28B confers radio-resistance through the posttranscriptional control of KRAS. Exp Mol Med 2009, 41:912-918.
    • (2009) Exp Mol Med , vol.41 , pp. 912-918
    • Jeong, S.H.1    Wu, H.G.2    Park, W.Y.3
  • 44
    • 72049101611 scopus 로고    scopus 로고
    • Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras
    • Oh J.S., Kim J.J., Byun J.Y., et al. Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras. Int J Radiat Oncol Biol Phys 2010, 76:5-8.
    • (2010) Int J Radiat Oncol Biol Phys , vol.76 , pp. 5-8
    • Oh, J.S.1    Kim, J.J.2    Byun, J.Y.3
  • 45
    • 77955429106 scopus 로고    scopus 로고
    • MicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN
    • Chun-Zhi Z., Lei H., An-Ling Z., et al. MicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN. BMC Cancer 2010, 10:367.
    • (2010) BMC Cancer , vol.10 , pp. 367
    • Chun-Zhi, Z.1    Lei, H.2    An-Ling, Z.3
  • 47
    • 77951463320 scopus 로고    scopus 로고
    • Hsa-mir-210 is a marker of tumor hypoxia and a prognostic factor in head and neck cancer
    • Gee H.E., Camps C., Buffa F.M., et al. hsa-mir-210 is a marker of tumor hypoxia and a prognostic factor in head and neck cancer. Cancer 2010, 116:2148-2158.
    • (2010) Cancer , vol.116 , pp. 2148-2158
    • Gee, H.E.1    Camps, C.2    Buffa, F.M.3
  • 48
    • 76349095132 scopus 로고    scopus 로고
    • Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
    • Semenza G.L. Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics. Oncogene 2010, 29:625-634.
    • (2010) Oncogene , vol.29 , pp. 625-634
    • Semenza, G.L.1
  • 49
    • 0038523737 scopus 로고    scopus 로고
    • Tumor hypoxia at the micro-regional level: Clinical relevance and predictive value of exogenous and endogenous hypoxic cell markers
    • Bussink J., Kaanders J.H., van der Kogel A.J. Tumor hypoxia at the micro-regional level: Clinical relevance and predictive value of exogenous and endogenous hypoxic cell markers. Radiother Oncol 2003, 67:3-15.
    • (2003) Radiother Oncol , vol.67 , pp. 3-15
    • Bussink, J.1    Kaanders, J.H.2    van der Kogel, A.J.3
  • 50
    • 0036883983 scopus 로고    scopus 로고
    • HIF-1A, pimonidazole, and iododeoxyuridine to estimate hypoxia and perfusion in human head-and-neck tumors
    • Janssen H.L., Haustermans K.M., Sprong D., et al. HIF-1A, pimonidazole, and iododeoxyuridine to estimate hypoxia and perfusion in human head-and-neck tumors. Int J Radiat Oncol Biol Phys 2002, 54:1537-1549.
    • (2002) Int J Radiat Oncol Biol Phys , vol.54 , pp. 1537-1549
    • Janssen, H.L.1    Haustermans, K.M.2    Sprong, D.3
  • 51
    • 34250182435 scopus 로고    scopus 로고
    • Lack of prognostic and predictive value of CA IX in radiotherapy of squamous cell carcinoma of the head and neck with known modifiable hypoxia: An evaluation of the DAHANCA 5 study
    • Danish Head and Neck Cancer Study Group (DAHANCA)
    • Eriksen J.G., Overgaard J. Lack of prognostic and predictive value of CA IX in radiotherapy of squamous cell carcinoma of the head and neck with known modifiable hypoxia: An evaluation of the DAHANCA 5 study. Radiother Oncol 2007, 83:383-388. Danish Head and Neck Cancer Study Group (DAHANCA).
    • (2007) Radiother Oncol , vol.83 , pp. 383-388
    • Eriksen, J.G.1    Overgaard, J.2
  • 52
    • 0031909654 scopus 로고    scopus 로고
    • A randomized double-blind phase III study of nimorazole as a hypoxic radiosensitizer of primary radiotherapy in supraglottic larynx and pharynx carcinoma. Results of the Danish Head and Neck Cancer Study (DAHANCA) protocols 5-85
    • Overgaard J., Hansen H.S., Overgaard M., et al. A randomized double-blind phase III study of nimorazole as a hypoxic radiosensitizer of primary radiotherapy in supraglottic larynx and pharynx carcinoma. Results of the Danish Head and Neck Cancer Study (DAHANCA) protocols 5-85. Radiother Oncol 1998, 46:135-146.
    • (1998) Radiother Oncol , vol.46 , pp. 135-146
    • Overgaard, J.1    Hansen, H.S.2    Overgaard, M.3
  • 53
    • 26844468059 scopus 로고    scopus 로고
    • The prognostic value of the hypoxia markers CA IX and GLUT 1 and the cytokines VEGF and IL 6 in head and neck squamous cell carcinoma treated by radiotherapy +/- chemotherapy
    • De S.H., Landuyt W., Verbeken E., et al. The prognostic value of the hypoxia markers CA IX and GLUT 1 and the cytokines VEGF and IL 6 in head and neck squamous cell carcinoma treated by radiotherapy +/- chemotherapy. BMC Cancer 2005, 5:42.
    • (2005) BMC Cancer , vol.5 , pp. 42
    • De, S.H.1    Landuyt, W.2    Verbeken, E.3
  • 54
    • 34548391012 scopus 로고    scopus 로고
    • Microvessel density >or=60 does not predict for outcome after radiation treatment for locally advanced head and neck squamous cell carcinoma: Results of a correlative study from the Radiation Therapy Oncology Group (RTOG) 90-03 Trial
    • Calvin D.P., Hammond M.E., Pajak T.F., et al. Microvessel density >or=60 does not predict for outcome after radiation treatment for locally advanced head and neck squamous cell carcinoma: Results of a correlative study from the Radiation Therapy Oncology Group (RTOG) 90-03 Trial. Am J Clin Oncol 2007, 30:406-419.
    • (2007) Am J Clin Oncol , vol.30 , pp. 406-419
    • Calvin, D.P.1    Hammond, M.E.2    Pajak, T.F.3
  • 55
    • 79952202229 scopus 로고    scopus 로고
    • Hyperfractionated or accelerated radiotherapy for head and neck cancer
    • CD002026
    • Baujat B., Bourhis J., Blanchard P., et al. Hyperfractionated or accelerated radiotherapy for head and neck cancer. Cochrane Database Syst Rev 2010, CD002026.
    • (2010) Cochrane Database Syst Rev
    • Baujat, B.1    Bourhis, J.2    Blanchard, P.3
  • 56
    • 0033048862 scopus 로고    scopus 로고
    • The value of pretreatment cell kinetic parameters as predictors for radiotherapy outcome in head and neck cancer: A multicenter analysis
    • Begg A.C., Haustermans K., Hart A.A., et al. The value of pretreatment cell kinetic parameters as predictors for radiotherapy outcome in head and neck cancer: A multicenter analysis. Radiother Oncol 1999, 50:13-23.
    • (1999) Radiother Oncol , vol.50 , pp. 13-23
    • Begg, A.C.1    Haustermans, K.2    Hart, A.A.3
  • 57
    • 0036468788 scopus 로고    scopus 로고
    • P53 and Ki-67 as markers of radioresistance in head and neck carcinoma
    • Couture C., Raybaud-Diogène H., Têtu B., et al. p53 and Ki-67 as markers of radioresistance in head and neck carcinoma. Cancer 2002, 94:713-722.
    • (2002) Cancer , vol.94 , pp. 713-722
    • Couture, C.1    Raybaud-Diogène, H.2    Têtu, B.3
  • 59
    • 0034134366 scopus 로고    scopus 로고
    • Nuclear DNA content, an adjunct to p53 and Ki-67 as a marker of resistance to radiation therapy in oral cavity and pharyngeal squamous cell carcinoma
    • Raybaud H., Fortin A., Bairati I., et al. Nuclear DNA content, an adjunct to p53 and Ki-67 as a marker of resistance to radiation therapy in oral cavity and pharyngeal squamous cell carcinoma. Int J Oral Maxillofac Surg 2000, 29:36-41.
    • (2000) Int J Oral Maxillofac Surg , vol.29 , pp. 36-41
    • Raybaud, H.1    Fortin, A.2    Bairati, I.3
  • 60
    • 13844297611 scopus 로고    scopus 로고
    • The role of epidermal growth factor receptor and E-cadherin for the outcome of reduction in the overall treatment time of radiotherapy of supraglottic larynx squamous cell carcinoma
    • Eriksen J.G., Steiniche T., Overgaard J., et al. The role of epidermal growth factor receptor and E-cadherin for the outcome of reduction in the overall treatment time of radiotherapy of supraglottic larynx squamous cell carcinoma. Acta Oncol 2005, 44:50-58.
    • (2005) Acta Oncol , vol.44 , pp. 50-58
    • Eriksen, J.G.1    Steiniche, T.2    Overgaard, J.3
  • 61
    • 24944479590 scopus 로고    scopus 로고
    • Epidermal growth factor receptor expression in pretreatment biopsies from head and neck squamous cell carcinoma as a predictive factor for a benefit from accelerated radiation therapy in a randomized controlled trial
    • Bentzen S.M., Atasoy B.M., Daley F.M., et al. Epidermal growth factor receptor expression in pretreatment biopsies from head and neck squamous cell carcinoma as a predictive factor for a benefit from accelerated radiation therapy in a randomized controlled trial. J Clin Oncol 2005, 23:5560-5567.
    • (2005) J Clin Oncol , vol.23 , pp. 5560-5567
    • Bentzen, S.M.1    Atasoy, B.M.2    Daley, F.M.3
  • 62
    • 2542559829 scopus 로고    scopus 로고
    • Molecular marker profiles predict locoregional control of head and neck squamous cell carcinoma in a randomized trial of continuous hyperfractionated accelerated radiotherapy
    • Buffa F.M., Bentzen S.M., Daley F.M., et al. Molecular marker profiles predict locoregional control of head and neck squamous cell carcinoma in a randomized trial of continuous hyperfractionated accelerated radiotherapy. Clin Cancer Res 2004, 10:3745-3754.
    • (2004) Clin Cancer Res , vol.10 , pp. 3745-3754
    • Buffa, F.M.1    Bentzen, S.M.2    Daley, F.M.3
  • 63
    • 56749154378 scopus 로고    scopus 로고
    • Robust prognostic value of a knowledge-based proliferation signature across large patient microarray studies spanning different cancer types
    • Starmans M.H., Krishnapuram B., Steck H., et al. Robust prognostic value of a knowledge-based proliferation signature across large patient microarray studies spanning different cancer types. Br J Cancer 2008, 99:1884-1890.
    • (2008) Br J Cancer , vol.99 , pp. 1884-1890
    • Starmans, M.H.1    Krishnapuram, B.2    Steck, H.3
  • 64
    • 69949188058 scopus 로고    scopus 로고
    • The use of a comprehensive tumour xenograft dataset to validate gene signatures relevant for radiation response
    • Starmans M.H., Zips D., Wouters B.G., et al. The use of a comprehensive tumour xenograft dataset to validate gene signatures relevant for radiation response. Radiother Oncol 2009, 92:417-422.
    • (2009) Radiother Oncol , vol.92 , pp. 417-422
    • Starmans, M.H.1    Zips, D.2    Wouters, B.G.3
  • 65
    • 24744452428 scopus 로고    scopus 로고
    • Selective inhibition of Ras, phosphoinositide 3 kinase, and Akt isoforms increases the radiosensitivity of human carcinoma cell lines
    • Kim I.A., Bae S.S., Fernandes A., et al. Selective inhibition of Ras, phosphoinositide 3 kinase, and Akt isoforms increases the radiosensitivity of human carcinoma cell lines. Cancer Res 2005, 65:7902-7910.
    • (2005) Cancer Res , vol.65 , pp. 7902-7910
    • Kim, I.A.1    Bae, S.S.2    Fernandes, A.3
  • 66
    • 0036304685 scopus 로고    scopus 로고
    • Local recurrence in head and neck cancer: Relationship to radiation resistance and signal transduction
    • Gupta A.K., McKenna W.G., Weber C.N., et al. Local recurrence in head and neck cancer: Relationship to radiation resistance and signal transduction. Clin Cancer Res 2002, 8:885-892.
    • (2002) Clin Cancer Res , vol.8 , pp. 885-892
    • Gupta, A.K.1    McKenna, W.G.2    Weber, C.N.3
  • 67
    • 28044447399 scopus 로고    scopus 로고
    • Akt activation correlates with adverse outcome in tongue cancer
    • Massarelli E., Liu D.D., Lee J.J., et al. Akt activation correlates with adverse outcome in tongue cancer. Cancer 2005, 104:2430-2436.
    • (2005) Cancer , vol.104 , pp. 2430-2436
    • Massarelli, E.1    Liu, D.D.2    Lee, J.J.3
  • 68
    • 0037115674 scopus 로고    scopus 로고
    • Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma
    • Ang K.K., Berkey B.A., Tu X., et al. Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma. Cancer Res 2002, 62:7350-7356.
    • (2002) Cancer Res , vol.62 , pp. 7350-7356
    • Ang, K.K.1    Berkey, B.A.2    Tu, X.3
  • 69
    • 33748653109 scopus 로고    scopus 로고
    • Increased epidermal growth factor receptor gene copy number is associated with poor prognosis in head and neck squamous cell carcinomas
    • Chung C.H., Ely K., McGavran L., et al. Increased epidermal growth factor receptor gene copy number is associated with poor prognosis in head and neck squamous cell carcinomas. J Clin Oncol 2006, 24:4170-4176.
    • (2006) J Clin Oncol , vol.24 , pp. 4170-4176
    • Chung, C.H.1    Ely, K.2    McGavran, L.3
  • 70
    • 56349163790 scopus 로고    scopus 로고
    • Molecular target approaches in head and neck cancer: Epidermal growth factor receptor and beyond
    • Harari P.M., Wheeler D.L., Grandis J.R. Molecular target approaches in head and neck cancer: Epidermal growth factor receptor and beyond. Semin Radiat Oncol 2009, 19:63-68.
    • (2009) Semin Radiat Oncol , vol.19 , pp. 63-68
    • Harari, P.M.1    Wheeler, D.L.2    Grandis, J.R.3
  • 71
    • 34548680936 scopus 로고    scopus 로고
    • Survival of squamous cell carcinoma of the head and neck in relation to human papillomavirus infection: Review and meta-analysis
    • Ragin C.C., Taioli E. Survival of squamous cell carcinoma of the head and neck in relation to human papillomavirus infection: Review and meta-analysis. Int J Cancer 2007, 121:1813-1820.
    • (2007) Int J Cancer , vol.121 , pp. 1813-1820
    • Ragin, C.C.1    Taioli, E.2
  • 72
    • 65349173893 scopus 로고    scopus 로고
    • Effect of HPV-associated p16INK4A expression on response to radiotherapy and survival in squamous cell carcinoma of the head and neck
    • Lassen P., Eriksen J.G., Hamilton-Dutoit S., et al. Effect of HPV-associated p16INK4A expression on response to radiotherapy and survival in squamous cell carcinoma of the head and neck. J Clin Oncol 2009, 27:1992-1998.
    • (2009) J Clin Oncol , vol.27 , pp. 1992-1998
    • Lassen, P.1    Eriksen, J.G.2    Hamilton-Dutoit, S.3
  • 73
    • 77954190940 scopus 로고    scopus 로고
    • Human papillomavirus and survival of patients with oropharyngeal cancer
    • Ang K.K., Harris J., Wheeler R., et al. Human papillomavirus and survival of patients with oropharyngeal cancer. N Engl J Med 2010, 363:24-35.
    • (2010) N Engl J Med , vol.363 , pp. 24-35
    • Ang, K.K.1    Harris, J.2    Wheeler, R.3
  • 74
    • 77953359433 scopus 로고    scopus 로고
    • Refining the diagnosis of oropharyngeal squamous cell carcinoma using human papillomavirus testing
    • Robinson M., Sloan P., Shaw R. Refining the diagnosis of oropharyngeal squamous cell carcinoma using human papillomavirus testing. Oral Oncol 2010, 46:492-496.
    • (2010) Oral Oncol , vol.46 , pp. 492-496
    • Robinson, M.1    Sloan, P.2    Shaw, R.3
  • 75
    • 32944464047 scopus 로고    scopus 로고
    • Gene expression differences associated with human papillomavirus status in head and neck squamous cell carcinoma
    • Slebos R.J., Yi Y., Ely K., et al. Gene expression differences associated with human papillomavirus status in head and neck squamous cell carcinoma. Clin Cancer Res 2006, 12:701-709.
    • (2006) Clin Cancer Res , vol.12 , pp. 701-709
    • Slebos, R.J.1    Yi, Y.2    Ely, K.3
  • 76
    • 60849085709 scopus 로고    scopus 로고
    • Genomewide gene expression profiles of HPV-positive and HPV-negative oropharyngeal cancer: Potential implications for treatment choices
    • Lohavanichbutr P., Houck J., Fan W., et al. Genomewide gene expression profiles of HPV-positive and HPV-negative oropharyngeal cancer: Potential implications for treatment choices. Arch Otolaryngol Head Neck Surg 2009, 135:180-188.
    • (2009) Arch Otolaryngol Head Neck Surg , vol.135 , pp. 180-188
    • Lohavanichbutr, P.1    Houck, J.2    Fan, W.3
  • 77
    • 77952583995 scopus 로고    scopus 로고
    • HPV and high-risk gene expression profiles predict response to chemoradiotherapy in head and neck cancer, independent of clinical factors
    • de Jong M.C., Pramana J., Knegjens J.L., et al. HPV and high-risk gene expression profiles predict response to chemoradiotherapy in head and neck cancer, independent of clinical factors. Radiother Oncol 2010, 95:365-370.
    • (2010) Radiother Oncol , vol.95 , pp. 365-370
    • de Jong, M.C.1    Pramana, J.2    Knegjens, J.L.3
  • 78
    • 74549123751 scopus 로고    scopus 로고
    • HPV-associated p16-expression and response to hypoxic modification of radiotherapy in head and neck cancer
    • Lassen P., Eriksen J.G., Hamilton-Dutoit S., et al. HPV-associated p16-expression and response to hypoxic modification of radiotherapy in head and neck cancer. Radiother Oncol 2010, 94:30-35.
    • (2010) Radiother Oncol , vol.94 , pp. 30-35
    • Lassen, P.1    Eriksen, J.G.2    Hamilton-Dutoit, S.3
  • 79
    • 79953871071 scopus 로고    scopus 로고
    • High stromal carbonic anhydrase IX expression is associated with decreased survival in P16-negative head-and-neck tumors
    • Brockton N., Dort J., Lau H., et al. High stromal carbonic anhydrase IX expression is associated with decreased survival in P16-negative head-and-neck tumors. Int J Radiat Oncol Biol Phys 2011, 80:249-257.
    • (2011) Int J Radiat Oncol Biol Phys , vol.80 , pp. 249-257
    • Brockton, N.1    Dort, J.2    Lau, H.3
  • 80
    • 33750313208 scopus 로고    scopus 로고
    • Cancer stem cells-Perspectives on current status and future directions: AACR workshop on cancer stem cells
    • Clarke M.F., Dick J.E., Dirks P.B., et al. Cancer stem cells-Perspectives on current status and future directions: AACR workshop on cancer stem cells. Cancer Res 2006, 66:9339-9344.
    • (2006) Cancer Res , vol.66 , pp. 9339-9344
    • Clarke, M.F.1    Dick, J.E.2    Dirks, P.B.3
  • 81
  • 83
    • 20444457518 scopus 로고    scopus 로고
    • Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer
    • Glinsky G.V., Berezovska O., Glinskii A.B. Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer. J Clin Invest 2005, 115:1503-1521.
    • (2005) J Clin Invest , vol.115 , pp. 1503-1521
    • Glinsky, G.V.1    Berezovska, O.2    Glinskii, A.B.3
  • 84
    • 77958467209 scopus 로고    scopus 로고
    • Elimination of head and neck cancer initiating cells through targeting glucose regulated protein78 signaling
    • 283
    • Wu M.J., Jan C.I., Tsay Y.G., et al. Elimination of head and neck cancer initiating cells through targeting glucose regulated protein78 signaling. Mol Cancer 2010, 9:283. 283.
    • (2010) Mol Cancer , vol.9 , pp. 283
    • Wu, M.J.1    Jan, C.I.2    Tsay, Y.G.3
  • 85
    • 34250174504 scopus 로고    scopus 로고
    • The role of epithelial-mesenchymal transition in cancer pathology
    • Guarino M., Rubino B., Ballabio G. The role of epithelial-mesenchymal transition in cancer pathology. Pathology 2007, 39:305-318.
    • (2007) Pathology , vol.39 , pp. 305-318
    • Guarino, M.1    Rubino, B.2    Ballabio, G.3
  • 86
    • 53249130662 scopus 로고    scopus 로고
    • Molecular signature and therapeutic perspective of the epithelial-to-mesenchymal transitions in epithelial cancers
    • Sabbah M., Emami S., Redeuilh G., et al. Molecular signature and therapeutic perspective of the epithelial-to-mesenchymal transitions in epithelial cancers. Drug Resist Update 2008, 11:123-151.
    • (2008) Drug Resist Update , vol.11 , pp. 123-151
    • Sabbah, M.1    Emami, S.2    Redeuilh, G.3
  • 87
    • 33748057486 scopus 로고    scopus 로고
    • Gene expression profiles identify epithelial-to-mesenchymal transition and activation of nuclear factor-kappaB signaling as characteristics of a high-risk head and neck squamous cell carcinoma
    • Chung C.H., Parker J.S., Ely K., et al. Gene expression profiles identify epithelial-to-mesenchymal transition and activation of nuclear factor-kappaB signaling as characteristics of a high-risk head and neck squamous cell carcinoma. Cancer Res 2006, 66:8210-8218.
    • (2006) Cancer Res , vol.66 , pp. 8210-8218
    • Chung, C.H.1    Parker, J.S.2    Ely, K.3
  • 88
    • 79960360062 scopus 로고    scopus 로고
    • E-Cadherin loss associated with EMT promotes radioresistance in human tumor cells
    • Theys J., Jutten B., Habets R., et al. E-Cadherin loss associated with EMT promotes radioresistance in human tumor cells. Radiother Oncol 2011, 99:392-397.
    • (2011) Radiother Oncol , vol.99 , pp. 392-397
    • Theys, J.1    Jutten, B.2    Habets, R.3
  • 89
    • 54049101143 scopus 로고    scopus 로고
    • Hypermethylation of E-cadherin is an independent predictor of improved survival in head and neck squamous cell carcinoma
    • Marsit C.J., Posner M.R., McClean M.D., et al. Hypermethylation of E-cadherin is an independent predictor of improved survival in head and neck squamous cell carcinoma. Cancer 2008, 113:1566-1571.
    • (2008) Cancer , vol.113 , pp. 1566-1571
    • Marsit, C.J.1    Posner, M.R.2    McClean, M.D.3
  • 90
    • 77954032829 scopus 로고    scopus 로고
    • Poly(ADP)-ribose polymerase inhibition: Frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval
    • Fong P.C., Yap T.A., Boss D.S., et al. Poly(ADP)-ribose polymerase inhibition: Frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval. J Clin Oncol 2010, 28:2512-2519.
    • (2010) J Clin Oncol , vol.28 , pp. 2512-2519
    • Fong, P.C.1    Yap, T.A.2    Boss, D.S.3
  • 91
    • 78751629661 scopus 로고    scopus 로고
    • BRCA1 CpG island hypermethylation predicts sensitivity to poly(adenosine diphosphate)-ribose polymerase inhibitors
    • Veeck J., Ropero S., Setien F., et al. BRCA1 CpG island hypermethylation predicts sensitivity to poly(adenosine diphosphate)-ribose polymerase inhibitors. J Clin Oncol 2010, 28:e563-e564.
    • (2010) J Clin Oncol , vol.28
    • Veeck, J.1    Ropero, S.2    Setien, F.3
  • 92
    • 70349166545 scopus 로고    scopus 로고
    • Prediction of BRCA1-association in hereditary non-BRCA1/2 breast carcinomas with array-CGH
    • Joosse S.A., van Beers E.H., Tielen I.H., et al. Prediction of BRCA1-association in hereditary non-BRCA1/2 breast carcinomas with array-CGH. Breast Cancer Res Treat 2009, 116:479-489.
    • (2009) Breast Cancer Res Treat , vol.116 , pp. 479-489
    • Joosse, S.A.1    van Beers, E.H.2    Tielen, I.H.3
  • 93
    • 69449090092 scopus 로고    scopus 로고
    • Utility of DNA repair protein foci for the detection of putative BRCA1 pathway defects in breast cancer biopsies
    • Willers H., Taghian A.G., Luo C.M., et al. Utility of DNA repair protein foci for the detection of putative BRCA1 pathway defects in breast cancer biopsies. Mol Cancer Res 2009, 7:1304-1309.
    • (2009) Mol Cancer Res , vol.7 , pp. 1304-1309
    • Willers, H.1    Taghian, A.G.2    Luo, C.M.3
  • 94
    • 77949545721 scopus 로고    scopus 로고
    • Inactivation of the tumor suppressor genes causing the hereditary syndromes predisposing to head and neck cancer via promoter hypermethylation in sporadic head and neck cancers
    • Smith I.M., Mithani S.K., Mydlarz W.K., et al. Inactivation of the tumor suppressor genes causing the hereditary syndromes predisposing to head and neck cancer via promoter hypermethylation in sporadic head and neck cancers. ORL J Otorhinolaryngol Relat Spec 2010, 72:44-50.
    • (2010) ORL J Otorhinolaryngol Relat Spec , vol.72 , pp. 44-50
    • Smith, I.M.1    Mithani, S.K.2    Mydlarz, W.K.3
  • 95
    • 79960004439 scopus 로고    scopus 로고
    • Pyrosequencing-based DNA methylation profiling of Fanconi anemia/BRCA pathway genes in laryngeal squamous cell carcinoma
    • Szaumkessel M., Richter J., Giefing M., et al. Pyrosequencing-based DNA methylation profiling of Fanconi anemia/BRCA pathway genes in laryngeal squamous cell carcinoma. Int J Oncol 2011, 39:505-514.
    • (2011) Int J Oncol , vol.39 , pp. 505-514
    • Szaumkessel, M.1    Richter, J.2    Giefing, M.3
  • 96
    • 77149157867 scopus 로고    scopus 로고
    • Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors
    • Mendes-Pereira A.M., Martin S.A., Brough R., et al. Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors. EMBO. Mol Med 2009, 1:315-322.
    • (2009) EMBO. Mol Med , vol.1 , pp. 315-322
    • Mendes-Pereira, A.M.1    Martin, S.A.2    Brough, R.3
  • 97
    • 77956490653 scopus 로고    scopus 로고
    • Targeting base excision repair as a sensitization strategy in radiotherapy
    • Vens C., Begg A.C. Targeting base excision repair as a sensitization strategy in radiotherapy. Semin Radiat Oncol 2010, 20:241-249.
    • (2010) Semin Radiat Oncol , vol.20 , pp. 241-249
    • Vens, C.1    Begg, A.C.2
  • 98
    • 78449302142 scopus 로고    scopus 로고
    • Targeted radiosensitization of cells expressing truncated DNA polymerase {beta}
    • Neijenhuis S., Verwijs-Janssen M., van den Broek L.J., et al. Targeted radiosensitization of cells expressing truncated DNA polymerase {beta}. Cancer Res 2010, 70:8706-8714.
    • (2010) Cancer Res , vol.70 , pp. 8706-8714
    • Neijenhuis, S.1    Verwijs-Janssen, M.2    van den Broek, L.J.3
  • 99
    • 77950867012 scopus 로고    scopus 로고
    • Novel therapeutics in combination with radiotherapy to improve cancer treatment: Rationale, mechanisms of action and clinical perspective
    • Verheij M., Vens C., van Triest B. Novel therapeutics in combination with radiotherapy to improve cancer treatment: Rationale, mechanisms of action and clinical perspective. Drug Resist Updat 2010, 13:29-43.
    • (2010) Drug Resist Updat , vol.13 , pp. 29-43
    • Verheij, M.1    Vens, C.2    van Triest, B.3
  • 100
    • 79955592811 scopus 로고    scopus 로고
    • Harnessing synthetic lethal interactions in anticancer drug discovery
    • Chan D.A., Giaccia A.J. Harnessing synthetic lethal interactions in anticancer drug discovery. Nat Rev Drug Discov 2011, 10:351-364.
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 351-364
    • Chan, D.A.1    Giaccia, A.J.2
  • 101
    • 5444264596 scopus 로고    scopus 로고
    • Identification of novel prognosticators of outcome in squamous cell carcinoma of the head and neck
    • Wreesmann V.B., Shi W., Thaler H.T., et al. Identification of novel prognosticators of outcome in squamous cell carcinoma of the head and neck. J Clin Oncol 2004, 22:3965-3972.
    • (2004) J Clin Oncol , vol.22 , pp. 3965-3972
    • Wreesmann, V.B.1    Shi, W.2    Thaler, H.T.3
  • 102
    • 40349096416 scopus 로고    scopus 로고
    • Cortactin expression predicts poor survival in laryngeal carcinoma
    • Gibcus J.H., Mastik M.F., Menkema L., et al. Cortactin expression predicts poor survival in laryngeal carcinoma. Br J Cancer 2008, 98:950-955.
    • (2008) Br J Cancer , vol.98 , pp. 950-955
    • Gibcus, J.H.1    Mastik, M.F.2    Menkema, L.3
  • 103
    • 62849094790 scopus 로고    scopus 로고
    • Distinctive clinicopathological associations of amplification of the cortactin gene at 11q13 in head and neck squamous cell carcinomas
    • Rodrigo J.P., García-Carracedo D., García L.A., et al. Distinctive clinicopathological associations of amplification of the cortactin gene at 11q13 in head and neck squamous cell carcinomas. J Pathol 2009, 217:516-523.
    • (2009) J Pathol , vol.217 , pp. 516-523
    • Rodrigo, J.P.1    García-Carracedo, D.2    García, L.A.3
  • 104
    • 17144399942 scopus 로고    scopus 로고
    • Cortactin overexpression inhibits ligand-induced down-regulation of the epidermal growth factor receptor
    • Timpson P., Lynch D.K., Schramek D., et al. Cortactin overexpression inhibits ligand-induced down-regulation of the epidermal growth factor receptor. Cancer Res 2005, 65:3273-3280.
    • (2005) Cancer Res , vol.65 , pp. 3273-3280
    • Timpson, P.1    Lynch, D.K.2    Schramek, D.3
  • 105
    • 68549097914 scopus 로고    scopus 로고
    • Downregulation of SERPINB13 expression in head and neck squamous cell carcinomas associates with poor clinical outcome
    • de Koning P.J., Bovenschen N., Leusink F.K., et al. Downregulation of SERPINB13 expression in head and neck squamous cell carcinomas associates with poor clinical outcome. Int J Cancer 2009, 125:1542-1550.
    • (2009) Int J Cancer , vol.125 , pp. 1542-1550
    • de Koning, P.J.1    Bovenschen, N.2    Leusink, F.K.3
  • 106
    • 29244439610 scopus 로고    scopus 로고
    • Headpin: A serpin with endogenous and exogenous suppression of angiogenesis
    • Shellenberger T.D., Mazumdar A., Henderson Y., et al. Headpin: A serpin with endogenous and exogenous suppression of angiogenesis. Cancer Res 2005, 65:11501-11509.
    • (2005) Cancer Res , vol.65 , pp. 11501-11509
    • Shellenberger, T.D.1    Mazumdar, A.2    Henderson, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.