Low dose palliative radiotherapy for splenomegaly in hematologic disorders

Leukemia and Lymphoma

Volumn 53, Issue 3, 2012, Pages 430-434

  Lavrenkov, Konstantin ^a,b   Krepel Volsky, Sari ^a   Levi, Itai ^a,b   Ariad, Samuel ^a,b  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

Lymphoproliferative disorders; Myeloproliferative disorders; Radiation therapy; Splenomegaly

Indexed keywords

ADULT; AGED; ANEMIA; ARTICLE; CACHEXIA; CANCER PALLIATIVE THERAPY; CANCER SURVIVAL; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL ARTICLE; FEMALE; HAIRY CELL LEUKEMIA; HEMATOLOGIC DISEASE; HUMAN; LEUKOPENIA; LOW ENERGY RADIATION; LYMPHOMA; MALE; MYELOPROLIFERATIVE DISORDER; PAIN; PRIORITY JOURNAL; RADIATION DOSE FRACTIONATION; RETROSPECTIVE STUDY; SPLEEN SIZE; SPLENOMEGALY; THROMBOCYTOPENIA;

ABDOMINAL PAIN; ADULT; AGED; ANEMIA; DOSE FRACTIONATION; FEMALE; HEMATOLOGIC NEOPLASMS; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; MYELOPROLIFERATIVE DISORDERS; PALLIATIVE CARE; RADIOTHERAPY, HIGH-ENERGY; RETROSPECTIVE STUDIES; SPLENOMEGALY; THROMBOCYTOPENIA; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84857552232     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.3109/10428194.2011.614708     Document Type: Article

References (27)

1. W eimann M, Becker G, Einsele H., et al. Clinical indications and biological mechanisms of splenic irradiation in chronic leukemias and myeloprolipherative disorders. Radiother Oncol 2001;58:235-236.
2. Bressler H, Notti I, Cohen AM., et al. Inhibition of leukemic cell proliferation by factors released from irradiated lymphocytes of B-chronic lymphocytic leukemia patients. Am J Hematol 1994;46: 65-71. (Pubitemid 24181614)
3. Delic J, Magdelenat H, Barbaroux C., et al. In-vivo induction of apoptosis in human lymphocytes by therapeutic fractionated total body irradiation. Br. J. Radiol. 1995;94:105-108.
4. Terstappen LWMM, De Grooth BG, van Berkel W., et al. Th e eff ect of splenic irradiation on lymphocyte subpopulations in chronic B-lymphocytic leukemia. Eur. J. Haematol. 1988;41:496-505. (Pubitemid 19022282)
5. B elka C, Ottinger H, Kreuzfelder E., et al. Impact of localized radiotherapy on peripheral blood immune cell counts and function in humans. Radiother Oncol 1999;50:199-204. (Pubitemid 29155546)
6. N azmy MS, Radwan A, Mokhtar M. Palliative spleen irradiation: Can we standardize its technique? J Egypt Nat Cancer Inst 2008;20: 31-35.
7. C ommon Terminology Criteria for Adverse Events (CTCAE), version 3.0. Bethesda, MD: National Cancer Institute; 2003.
8. S andler J. A test of the signifi cance of the diff erence between the means of correlated measures, based on a simplifi cation of Student ' s t. Br J Psychol 1955;46:225-226.
9. D unn-Rankin P, Wilcoxon F. Th e true distributions of the range of rank totals in the two-way classifi cation. Psychometrika 1966;31: 573-580.
10. K aplan EI, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 1958;53:457-481.
11. M antel L, Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J. Natl. Cancer Inst. 1959;22:719-748.
12. S ingh AK, Bates T, Wetherley-Mein G. A preliminary study of low dose splenic irradiation for the treatment of chronic lymphocytic and promyelocytic leukemia. Scand J Haematol 1986;37:50-58. (Pubitemid 16016203)
13. B yhardt RW, Brace KC, Wiernick PH. Th e role of splenic irradiation in chronic lymphocytic leukemia. Cancer 1975;35:1621-1625.
14. C hisesi T, Capnist G, Dal Fior S. Splenic irradiation in chronic lymphocytic leukemia. Eur. J. Haematol. 1991;46:202-204.
15. A abo K, Walbom-Jorgensen DE. Splenic irradiation in chronic lymphocytic leukemia (CLL): Palliation in patients unfi t for splenectomy. Haematology 1985;19:117-128.
16. M arkus H, Forfar JC. Splenic irradiation in treating warm autoimmune haemolytic anaemia. Br Med J 1986;63:377-379.
17. Paulino AC, Raddy SP. Splenic irradiation in the palliation of patients with lymphoproliferative and myeloproliferative disorders. Am J Hosp Palliat Care 1996;13:32-36.
18. G onzague-Casabianca L, Bouabdallah R, Cowen D., et al. Splenic irradiation in myeloid hemopathies: Evaluation and toxicity. Cancer Radiother 1997;1:213-221. (Pubitemid 27319373)
19. E lliot MA, Chen MG, Silverstein MN., et al. Splenic irradiation for symptomatic splenomegaly associated with myelolfi brosis with myeloid metaplasia. Br. J. Haematol. 1998;102:505-511. (Pubitemid 28522460)
20. Yamamoto K, Hamaguchi H, Nagata K., et al. Splenic irradiation for prolymphocytic leukemia: Is it preferable as an initial treatment or not? Jpn J. Clin. Oncol. 1998;28:267-269. (Pubitemid 128523160)
21. Bouabdallah R, Cose D, Gonzague-Casabianca L., et al. Safety and effi cacy of splenic irradiation in the treatment of patients with idiopathic myelofi brosis:a report of 15 patients. Leuk Res 2000;24:491-495. (Pubitemid 30227227)
22. van Mook WNKA, Fickers MMF, Verschueren TAM. Clinical and immunological evaluation of primary splenic irradiation in chronic lymphocytic leukemia. Ann Hematol 2001;80:216-223. (Pubitemid 32421900)
23. M cFarland JT, Kuzma C, Millard FE., et al. Palliative irradiation of the spleen. Am J. Clin. Oncol. 2003;26:178-183. (Pubitemid 36443563)
24. Galdiero M, Cipollaro de l ' Ero G, Holgore A., et al. Eff ects of irradiation doses on alterations in cytokine release by monocytes and lymphocytes. J Med 1994;25:23-40. (Pubitemid 24204092)
25. Kost S, Keinert K, Endert G., et al. Strahlenfolgen der linken niere nach milzbestrahulng. Starhlenther Oncol 1998;175:415-420. (Pubitemid 28376214)
26. T amada K, Harada M, Abe K., et al. IL-4 producing NK1(- ) cells (Th 2) are resistant to glucocorticoid apoptosis: Implication for Th 1/Th 2 balance. J. Immunol. 1998;161:1239-1247.
27. G ray WC, Chretien PB, Suter CM., et al. Eff ect of radiation therapy on T-lymphocyte subpopulations in patients with head and neck cancer. Otolaryngol Head Neck Surg 1985;93:650-660. (Pubitemid 17056791)