Comparison of the anesthetic efficacy of articaine and mepivacaine in pediatric patients: A randomized, double-blind study

Pediatric Dentistry

Volumn 34, Issue 1, 2012, Pages 42-45

  Odabas, Mesut Enes ^a   Çinar, Cagdas ^a   Deveci, Ceren ^a   Alaçam, Alev ^a  

^a GAZI UNIVERSITY   (Turkey)

Author keywords

Articaine; Children; Local anesthetic; Mepivacaine

Indexed keywords

ARTICAINE; LOCAL ANESTHETIC AGENT; MEPIVACAINE; OXYGEN;

ADOLESCENT; ARTICLE; BLOOD; BLOOD PRESSURE; CHILD; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DENTAL ANESTHESIA; DENTAL PROCEDURE; DENTITION; DOUBLE BLIND PROCEDURE; DRUG EFFECT; FEMALE; HEART RATE; HUMAN; INJECTION; LOCAL ANESTHESIA; MALE; METHODOLOGY; PAIN ASSESSMENT; RANDOMIZED CONTROLLED TRIAL;

ADOLESCENT; ANESTHESIA, DENTAL; ANESTHESIA, LOCAL; ANESTHETICS, LOCAL; BLOOD PRESSURE; CARTICAINE; CHILD; DENTAL CARE FOR CHILDREN; DENTITION, PRIMARY; DOUBLE-BLIND METHOD; FEMALE; HEART RATE; HUMANS; INJECTIONS; MALE; MEPIVACAINE; OXYGEN; PAIN MEASUREMENT;

EID: 84857550909     PISSN: 01641263     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Milgrom P, Coldwell SE, Getz T, Weinstein P, Ramsay DS. Four dimensions of fear of dental injections. J Am Dent Assoc 1997;128:756-66.
2. Asarch T, Allen K, Petersen B, Beiraghi S. Efficacy of a computerized local anesthesia device in pediatric dentistry. Pediatr Dent 1999;21:421-4.
3. Kuscu OO, Akyuz S. Is it the injection device or the anxiety experienced that causes pain during dental local anesthesia? Int J Paediatr Dent 2008;18:139-45.
4. Roszkowski MT, Swift JQ, Hargreaves KM. Effect of NSAID administration on tissue levels of immunoreactive prostaglandin E2, leukotriene B4, and (S)-flurbiprofen following extraction of impacted third molars. Pain 1997;73: 339-45. (Pubitemid 28021837)
5. Dionne RA, Lepinski AM, Gordon SM, Jaber L, Brahim JS, Hargreaves KM. Analgesic effects of peripherally administered opioids in clinical models of acute and chronic inflammation. Clin Pharmacol Ther 2001;70:66-73. (Pubitemid 32678804)
6. Mestre Aspa R, Carrera Grano I, Berini Aytes L, Gay Escoda C. Pulsioxymetry monitorization during lower third molar extraction: A comparative study of 3 local anesthetics with epinephrine 1:100,000. Med Oral 2001;6:195-204. (Pubitemid 32537323)
7. McLean C, Reader A, Beck M, Meryers WJ. An evaluation of 4% prilocaine and 3% mepivacaine compared with 2% lidocaine (1:100,000 epinephrine) for inferior alveolar nerve block. J Endod 1993;19:146-50.
8. Cohen HP, Cha BY, Spangberg LS. Endodontic anesthesia in mandibular molars: A clinical study. J Endod 1993;19: 370-3.
9. Malamed SF, Gagnon S, Leblanc D. Articaine hydrochloride: A study of the safety of a new amide local anesthetic. J Am Dent Assoc 2001;132:177-85. (Pubitemid 33609893)
10. Cowan A. Clinical assessment of a new local anesthetic agent: Carticaine. Oral Surg Oral Med Oral Pathol 1977; 43:174-80. (Pubitemid 8042754)
11. Malamed SF, Gagnon S, Leblanc D. Efficacy of articaine: A new amide local anesthetic. J Am Dent Assoc 2000;131: 635-42.
12. Mikesell P, Nusstein J, Reader A, Beck M, Weaver J. A comparison of articaine and lidocaine for inferior alveolar nerve blocks. J Endod 2005;31:265-70. (Pubitemid 40522534)
13. Claffey E, Reader A, Nusstein J, Beck M, Weaver J. Anesthetic efficacy of articaine for inferior alveolar nerve blocks in patients with irreversible pulpitis. J Endod 2004;30: 568-71. (Pubitemid 39092209)
14. Berberich G, Reader A, Drum M, Nusstein J, Beck M. A prospective, randomized, double-blind comparison of the anesthetic efficacy of two percent lidocaine with 1:100,000 and 1:50,000 epinephrine and 3 percent mepivacaine in the intraoral, infraorbital nerve block. J Endod 2009;35: 1498-504.
15. Bieri D, Reeve RA, Champion GD, Addicoat L, Ziegler JB. The Faces Pain Scale for the self-assessment of the severity of pain experienced by children: Development, initial validation, and preliminary investigation for ratio scale properties. Pain 1990;41:139-50. (Pubitemid 20179927)
16. Taddio A, Nulman I, Goldbach M, Ipp M, Koren G. Use of lidocaine-prilocaine cream for vaccination pain in infants. J Pediatr 1994;124:643-8. (Pubitemid 24128167)
17. Jones CM, Heidmann J, Gerrish AC. Children's ratings of dental injection and treatment pain, and the influence of the time taken to administer the injection. Int J Paediatr Dent 1995;5:81-5.
18. Wong DL, Baker CM. Pain in children: Comparison of assessment scales. Pediatr Nurs 1988;14:9-17.
19. Ram D, Amir E. Comparison of articaine 4% and lidocaine 2% in pediatric dental patients. Int J Paediatr Dent 2006; 16:252-6. (Pubitemid 43825106)
20. Bortoluzzi M, Manfro R, Kafer G, Busetti L. Comparative study of articaine and mepivacaine: A double- blind, randomized, clinical trial. Internet Journal Dental Science 2009;7(1). Available at: "http://www.ispub.com/ journal/ the-internet-journal-of-dental-science/volume-7-number-1/ comparative-study-of-the-efficacy-of-articaine-and-mepi vacaine-a-double-blind- randomized-clinical-trial.html". Accessed December 19, 2011.
21. Donaldson D, James-Perdok L, Craig BJ, Derkson GD, Richardson AS. A comparison of Ultracaine DS (articaine HCl) and Citanest forte (prilocaine HCl) in maxillary infiltration and mandibular nerve block. J Can Dent Assoc 1987;53:38-42.
22. Colombini BL, Modena KC, Calvo AM, et al. Articaine and mepivacaine efficacy in postoperative analgesia for lower third molar removal: A double-blind, randomized, crossover study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006;102:169-74. (Pubitemid 44094159)
23. Malamed S. Handbook of Local Anesthesia. 5th ed. St. Louis, Mo: Elsevier Mosby; 2004.
24. Naftalin LW, Yagiela JA. Vasoconstrictors: Indications and precautions. Dent Clin North Am 2002;46:733-46, ix.