Cyclotides as a basis for drug design

Expert Opinion on Drug Discovery

Volumn 7, Issue 3, 2012, Pages 179-194

  Craik, David J ^a   Swedberg, Joakim E ^a   Mylne, Joshua S ^a   Cemazar, Masa ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Circular proteins; Cyclic peptides; Cyclotides; Cystine knot; Drug design; Kalata B1

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; CELL PENETRATING PEPTIDE; CIRCULIN; CYCLOPSYCHOTRIDE A; CYCLOTIDE; CYCLOTIDE MCOTI I; CYCLOTIDE MCOTI II; CYCLOTIDE VARV A; CYCLOTIDE VARV E; CYCLOTIDE VARV F; CYCLOTIDE VHL 1; CYCLOVIOLACIN O14; CYCLOVIOLACIN O15; CYCLOVIOLACIN O24; CYCLOVIOLIN A; CYCLOVIOLIN B; CYCLOVIOLIN C; CYCLOVIOLIN D; DEFENSIN; KALATA B1; KALATA B2; KALATA B8; KALLIKREIN; PALICOUREIN; RECOMBINANT PROTEIN; THETA DEFENSIN; TRYPSIN INHIBITOR; UNCLASSIFIED DRUG; UNINDEXED DRUG; UTEROTONIC AGENT; VITRI A;

AMINO ACID SEQUENCE; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; BIOLOGICAL ACTIVITY; CARDIOVASCULAR DISEASE; CYSTINE KNOT MOTIF; DISULFIDE BOND; DRUG DESIGN; HUMAN; INFECTION; MOMORDICA COCHINCHINENSIS; NEOPLASM; NONHUMAN; PLANT CELL; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN STABILITY; PROTEIN STRUCTURE; REVIEW; SOLID PHASE SYNTHESIS; STRUCTURE ACTIVITY RELATION;

ANIMALS; CARDIOVASCULAR DISEASES; COMMUNICABLE DISEASES; CYCLOTIDES; DRUG DESIGN; DRUG STABILITY; HUMANS; NEOPLASMS; PEPTIDES;

EID: 84857547296     PISSN: 17460441     EISSN: 1746045X     Source Type: Journal    
DOI: 10.1517/17460441.2012.661554     Document Type: Review

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