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Volumn 122, Issue 1-2, 2012, Pages 45-53

A new era for anticoagulation in atrial fibrillation. Which anticoagulant should we choose for long-term prevention of thromboembolic complications in patients with atrial fibrillation?

Author keywords

Apixaban; Atrial fibrillation; Dabigatran; Oral anticoagulants; Rivaroxaban

Indexed keywords

ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; ANTIDOTE; ANTIVITAMIN K; APIXABAN; BLOOD CLOTTING FACTOR 10A INHIBITOR; CLOPIDOGREL; DABIGATRAN; DABIGATRAN ETEXILATE; RIVAROXABAN; WARFARIN;

EID: 84857523007     PISSN: 00323772     EISSN: None     Source Type: Journal    
DOI: 10.20452/pamw.1133     Document Type: Review
Times cited : (25)

References (50)
  • 1
    • 33645470121 scopus 로고    scopus 로고
    • Prevalence, incidence and lifetime risk of atrial fibrillation: The Rotterdam study
    • Heeringa J, van der Kuip DA, Hofman A, et al. Prevalence, incidence and lifetime risk of atrial fibrillation: the Rotterdam study. Eur Heart J. 2006; 27: 949-953.
    • (2006) Eur Heart J , vol.27 , pp. 949-953
    • Heeringa, J.1    Van Der Kuip, D.A.2    Hofman, A.3
  • 2
    • 0025779484 scopus 로고
    • Atrial fibrillation as an independent risk factor for stroke: The Framingham Study
    • Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke. 1991; 22: 983-988.
    • (1991) Stroke , vol.22 , pp. 983-988
    • Wolf, P.A.1    Abbott, R.D.2    Kannel, W.B.3
  • 4
    • 34347394385 scopus 로고    scopus 로고
    • Meta-analysis: Antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation
    • Hart RG, Pearce LA, Aguilar MI. Meta-analysis: antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation. Ann Intern Med. 2007; 146: 857-867. (Pubitemid 351650486)
    • (2007) Annals of Internal Medicine , vol.146 , Issue.12 , pp. 857-867
    • Hart, R.G.1    Pearce, L.A.2    Aguilar, M.I.3
  • 5
    • 77957699729 scopus 로고    scopus 로고
    • Guidelines for the management of atrial fibrillation: The Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC)
    • European Heart Rhythm Association; European Association for Cardio-Thoracic Surgery
    • Camm AJ, Kirchhof P, Lip GY, et al.; European Heart Rhythm Association; European Association for Cardio-Thoracic Surgery. Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC). Eur Heart J. 2010; 31: 2369-2429.
    • (2010) Eur Heart J , vol.31 , pp. 2369-2429
    • Camm, A.J.1    Kirchhof, P.2    Lip, G.Y.3
  • 6
    • 45949103309 scopus 로고    scopus 로고
    • Pharmacology and management of the vitamin K antagonists: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
    • (8th Edition). American College of Chest Physicians
    • Ansell J, Hirsh J, Hylek E, et al.; American College of Chest Physicians. Pharmacology and management of the vitamin K antagonists: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 2008; 133 (6 Suppl): 160S-198S.
    • (2008) Chest , vol.133 , Issue.6 SUPPL.
    • Ansell, J.1    Hirsh, J.2    Hylek, E.3
  • 7
    • 77954369172 scopus 로고    scopus 로고
    • New oral anticoagulant drugs in cardiovascular disease
    • Ahrens I, Lip GY, Peter K. New oral anticoagulant drugs in cardiovascular disease. Thromb Haemost. 2010; 104: 49-60.
    • (2010) Thromb Haemost , vol.104 , pp. 49-60
    • Ahrens, I.1    Lip, G.Y.2    Peter, K.3
  • 8
    • 80155206426 scopus 로고    scopus 로고
    • Questions and answers on the use of dabigatran and perpectives on the use of other new oral anticoagulants in patients with atrial fibrillation. A consensus document of the Italian Federation of Thrombosis Centers (FCSA)
    • Pengo V, Crippa L, Falanga A, et al. Questions and answers on the use of dabigatran and perpectives on the use of other new oral anticoagulants in patients with atrial fibrillation. A consensus document of the Italian Federation of Thrombosis Centers (FCSA). Thromb Haemost. 2011; 106: 868-876.
    • (2011) Thromb Haemost , vol.106 , pp. 868-876
    • Pengo, V.1    Crippa, L.2    Falanga, A.3
  • 10
    • 79954456496 scopus 로고    scopus 로고
    • Dabigatran etexilate: A new oral thrombin inhibitor
    • Hankey GJ, Eikelboom JW. Dabigatran etexilate: a new oral thrombin inhibitor. Circulation. 2011; 123: 1436-1450.
    • (2011) Circulation , vol.123 , pp. 1436-1450
    • Hankey, G.J.1    Eikelboom, J.W.2
  • 11
    • 77952167209 scopus 로고    scopus 로고
    • Pharmacology, pharmacokinetics, and pharmacodynamics of dabigatran etexilate, an oral direct thrombin inhibitor
    • Stangier J, Clemens A. Pharmacology, pharmacokinetics, and pharmacodynamics of dabigatran etexilate, an oral direct thrombin inhibitor. Clin Appl Thromb Hemost. 2009; 15 Suppl 1: 9S-16S.
    • (2009) Clin Appl Thromb Hemost , vol.15 , Issue.SUPPL. 1
    • Stangier, J.1    Clemens, A.2
  • 12
    • 77953168824 scopus 로고    scopus 로고
    • Dabigatran etexilate - A novel, reversible, oral direct thrombin inhibitor: Interpretation of coagulation assays and reversal of anticoagulant activity
    • van Ryn J, Stangier J, Haertter S, et al. Dabigatran etexilate - a novel, reversible, oral direct thrombin inhibitor: interpretation of coagulation assays and reversal of anticoagulant activity. Thromb Haemost. 2010; 103: 1116-1127.
    • (2010) Thromb Haemost , vol.103 , pp. 1116-1127
    • Van Ryn, J.1    Stangier, J.2    Haertter, S.3
  • 13
    • 84857535494 scopus 로고    scopus 로고
    • Accessed November 21, 2011
    • European Medicines Agency. Pradaxa (dabigatran etexilate). Product information. http://www.ema.europa.eu/ docs/en-GB/ document-library/EPAR- Product-Information/human/000 829/WC500 041 059.pdf. Accessed November 21, 2011.
    • Pradaxa (Dabigatran Etexilate). Product Information
  • 14
    • 70349306707 scopus 로고    scopus 로고
    • Dabigatran versus warfarin in patients with atrial fibrillation
    • RE-LY Steering Committee and Investigators
    • Connolly SJ, Ezekowitz MD, Yusuf S, et al.; RE-LY Steering Committee and Investigators. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med. 2009; 361: 1139-1151.
    • (2009) N Engl J Med , vol.361 , pp. 1139-1151
    • Connolly, S.J.1    Ezekowitz, M.D.2    Yusuf, S.3
  • 15
    • 79958126202 scopus 로고    scopus 로고
    • Risk of bleeding with 2 doses of dabigatran compared with warfarin in older and younger patients with atrial fibrillation: An analysis of the randomized evaluation of long-term anticoagulant therapy (RE-LY) trial
    • Eikelboom JW, Wallentin L, Connolly SJ, et al. Risk of bleeding with 2 doses of dabigatran compared with warfarin in older and younger patients with atrial fibrillation: an analysis of the randomized evaluation of long-term anticoagulant therapy (RE-LY) trial. Circulation. 2011; 123: 2363-2372.
    • (2011) Circulation , vol.123 , pp. 2363-2372
    • Eikelboom, J.W.1    Wallentin, L.2    Connolly, S.J.3
  • 16
    • 78751637313 scopus 로고    scopus 로고
    • Dabigatran versus warfarin in patients with atrial fibrillation: An analysis of patients undergoing cardioversion
    • Nagarakanti R, Ezekowitz MD, Oldgren J, et al. Dabigatran versus warfarin in patients with atrial fibrillation: an analysis of patients undergoing cardioversion. Circulation. 2011; 123: 131-136.
    • (2011) Circulation , vol.123 , pp. 131-136
    • Nagarakanti, R.1    Ezekowitz, M.D.2    Oldgren, J.3
  • 17
    • 78349313002 scopus 로고    scopus 로고
    • Dabigatran compared with warfarin in patients with atrial fibrillation and previous transient ischaemic attack or stroke: A subgroup analysis of the RE-LY trial
    • RE-LY study group
    • Diener HC, Connolly SJ, Ezekowitz MD, et a.; RE-LY study group. Dabigatran compared with warfarin in patients with atrial fibrillation and previous transient ischaemic attack or stroke: a subgroup analysis of the RE-LY trial. Lancet Neurol. 2010; 9: 1157-1163.
    • (2010) Lancet Neurol , vol.9 , pp. 1157-1163
    • Diener, H.C.1    Connolly, S.J.2    Ezekowitz, M.D.3
  • 18
    • 78650114177 scopus 로고    scopus 로고
    • Dabigatran and warfarin in vitamin K antagonist-naive and -experienced cohorts with atrial fibrillation
    • RE-LY Steering Committee and Investigators
    • Ezekowitz MD, Wallentin L, Connolly SJ, et al.; RE-LY Steering Committee and Investigators. Dabigatran and warfarin in vitamin K antagonist-naive and -experienced cohorts with atrial fibrillation. Circulation. 2010; 122: 2246-2253.
    • (2010) Circulation , vol.122 , pp. 2246-2253
    • Ezekowitz, M.D.1    Wallentin, L.2    Connolly, S.J.3
  • 19
    • 84857571907 scopus 로고    scopus 로고
    • Dabigatran etexilate versus warfarin in patients with different types of atrial fibrillation: A RE-LY subgroup analysis
    • Flaker GC, Reilly P, Yusuf S, et al. Dabigatran etexilate versus warfarin in patients with different types of atrial fibrillation: a RE-LY subgroup analysis. J Am Coll Cardiol. 2011; 57: E62.
    • (2011) J Am Coll Cardiol , vol.57
    • Flaker, G.C.1    Reilly, P.2    Yusuf, S.3
  • 20
    • 77956977472 scopus 로고    scopus 로고
    • Efficacy and safety of dabigatran compared with warfarin at different levels of international normalised ratio control for stroke prevention in atrial fibrillation: An analysis of the RE-LY trial
    • RE-LY investigators
    • Wallentin L, Yusuf S, Ezekowitz MD, et al.; RE-LY investigators. Efficacy and safety of dabigatran compared with warfarin at different levels of international normalised ratio control for stroke prevention in atrial fibrillation: an analysis of the RE-LY trial. Lancet. 2010; 376: 975-983.
    • (2010) Lancet , vol.376 , pp. 975-983
    • Wallentin, L.1    Yusuf, S.2    Ezekowitz, M.D.3
  • 21
    • 79954469124 scopus 로고    scopus 로고
    • Dabigatran as anticoagulant therapy for atrial fibrillation. Which patients should receive it, which patients may not need it, and other practical aspects of patient management
    • Douketis JD. Dabigatran as anticoagulant therapy for atrial fibrillation. Which patients should receive it, which patients may not need it, and other practical aspects of patient management. Pol Arch Med Wewn. 2011; 121: 73-80.
    • (2011) Pol Arch Med Wewn , vol.121 , pp. 73-80
    • Douketis, J.D.1
  • 22
    • 71849117615 scopus 로고    scopus 로고
    • Dabigatran versus warfarin in the treatment of acute venous thromboembolism
    • RE-COVER Study Group
    • Schulman S, Kearon C, Kakkar AK, et al.; RE-COVER Study Group. Dabigatran versus warfarin in the treatment of acute venous thromboembolism. N Engl J Med. 2009; 361: 2342-2352.
    • (2009) N Engl J Med , vol.361 , pp. 2342-2352
    • Schulman, S.1    Kearon, C.2    Kakkar, A.K.3
  • 24
    • 78649734571 scopus 로고    scopus 로고
    • Treatments for stroke prevention in atrial fibrillation: A network meta-analysis and indirect comparisons versus dabigatran etexilate
    • Roskell NS, Lip GY, Noack H, et al. Treatments for stroke prevention in atrial fibrillation: a network meta-analysis and indirect comparisons versus dabigatran etexilate. Thromb Haemost. 2010; 104: 1106-1115.
    • (2010) Thromb Haemost , vol.104 , pp. 1106-1115
    • Roskell, N.S.1    Lip, G.Y.2    Noack, H.3
  • 27
    • 84941997771 scopus 로고    scopus 로고
    • Accessed November 13, 2011
    • Food and Drug Administration. Xarelto (rivaroxaban). Prescribing information. http://www.accessdata.fda.gov /drugsatfda-docs/label/2011/ 202439s000lbl.pdf. Accessed November 13, 2011.
    • Xarelto (Rivaroxaban). Prescribing Information
  • 28
    • 33645779998 scopus 로고    scopus 로고
    • Effect of food, an antacid, and the H2 antagonist ranitidine on the absorption of BAY 59-7939 (rivaroxaban), an oral, direct factor Xa inhibitor, in healthy subjects
    • Kubitza D, Becka M, Zuehlsdorf M, Mueck W. Effect of food, an antacid, and the H2 antagonist ranitidine on the absorption of BAY 59-7939 (rivaroxaban), an oral, direct factor Xa inhibitor, in healthy subjects. J Clin Pharmacol. 2006; 46: 549-558.
    • (2006) J Clin Pharmacol , vol.46 , pp. 549-558
    • Kubitza, D.1    Becka, M.2    Zuehlsdorf, M.3    Mueck, W.4
  • 29
    • 66449099711 scopus 로고    scopus 로고
    • Metabolism and excretion of rivaroxaban, an oral, direct factor Xa inhibitor, in rats, dogs, and humans
    • Weinz C, Schwarz T, Kubitza D, et al. Metabolism and excretion of rivaroxaban, an oral, direct factor Xa inhibitor, in rats, dogs, and humans. Drug Metab Dispos. 2009; 37: 1056-1064.
    • (2009) Drug Metab Dispos , vol.37 , pp. 1056-1064
    • Weinz, C.1    Schwarz, T.2    Kubitza, D.3
  • 30
    • 80052592404 scopus 로고    scopus 로고
    • Rivaroxaban versus warfarin in nonvalvular atrial fibrillation
    • ROCKET AF Investigators
    • Patel MR, Mahaffey KW, Garg J, et al.; ROCKET AF Investigators. Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. N Engl J Med. 2011; 365: 883-891.
    • (2011) N Engl J Med , vol.365 , pp. 883-891
    • Patel, M.R.1    Mahaffey, K.W.2    Garg, J.3
  • 31
    • 80052825103 scopus 로고    scopus 로고
    • Apixaban versus warfarin in patients with atrial fibrillation
    • ARISTOTLE Committees and Investigators
    • Granger CB, Alexander JH, McMurray JJ, et al.; ARISTOTLE Committees and Investigators. Apixaban versus warfarin in patients with atrial fibrillation. N Engl J Med. 2011; 365; 981-992.
    • (2011) N Engl J Med , vol.365 , pp. 981-992
    • Granger, C.B.1    Alexander, J.H.2    McMurray, J.J.3
  • 32
    • 51349095537 scopus 로고    scopus 로고
    • Population pharmacokinetics and pharmacodynamics of once- And twice-daily rivaroxaban for the prevention of venous thromboembolism in patients undergoing total hip replacement
    • Mueck W, Borris LC, Dahl OE, et al. Population pharmacokinetics and pharmacodynamics of once- and twice-daily rivaroxaban for the prevention of venous thromboembolism in patients undergoing total hip replacement. Thromb Haemost. 2008; 100: 453-461.
    • (2008) Thromb Haemost , vol.100 , pp. 453-461
    • Mueck, W.1    Borris, L.C.2    Dahl, O.E.3
  • 33
    • 78650619315 scopus 로고    scopus 로고
    • Oral rivaroxaban for symptomatic venous thromboembolism
    • EINSTEIN Investigators
    • EINSTEIN Investigators, Bauersachs R, Berkowitz SD, Brenner B, et al. Oral rivaroxaban for symptomatic venous thromboembolism. N Engl J Med. 2010; 363: 2499-2510.
    • (2010) N Engl J Med , vol.363 , pp. 2499-2510
    • Bauersachs, R.1    Berkowitz, S.D.2    Brenner, B.3
  • 34
    • 80054071757 scopus 로고    scopus 로고
    • Prevention of stroke and systemic embolism with rivaroxaban compared with warfarin in patients with non-valvular atrial fibrillation and moderate renal impairment
    • Fox KA, Piccini JP, Wojdyla D, et al. Prevention of stroke and systemic embolism with rivaroxaban compared with warfarin in patients with non-valvular atrial fibrillation and moderate renal impairment. Eur Heart J. 2011; 32: 2387-2394.
    • (2011) Eur Heart J , vol.32 , pp. 2387-2394
    • Fox, K.A.1    Piccini, J.P.2    Wojdyla, D.3
  • 35
    • 84923230761 scopus 로고    scopus 로고
    • Accessed November 24, 2011
    • European Medicines Agency. Xarelto (rivaroxaban). Product information. http://www.ema.europa.eu/docs/en-GB/document-library/EPAR---Product-Information/ human/000 944/WC500 057 108.pdf. Accessed November 24, 2011.
    • Xarelto (Rivaroxaban). Product Information
  • 36
    • 80052351015 scopus 로고    scopus 로고
    • Preclinical discovery of apixaban, a direct and orally bioavailable factor Xa inhibitor
    • Wong PC, Pinto DJ, Zhang D. Preclinical discovery of apixaban, a direct and orally bioavailable factor Xa inhibitor. J Thromb Thrombolysis. 2011; 31: 478-492.
    • (2011) J Thromb Thrombolysis , vol.31 , pp. 478-492
    • Wong, P.C.1    Pinto, D.J.2    Zhang, D.3
  • 37
    • 58149458160 scopus 로고    scopus 로고
    • Apixaban metabolism and pharmacokinetics after oral administration to humans
    • Raghavan N, Frost CE, Yu Z, et al. Apixaban metabolism and pharmacokinetics after oral administration to humans. Drug Metab Dispos. 2009; 37: 74-81.
    • (2009) Drug Metab Dispos , vol.37 , pp. 74-81
    • Raghavan, N.1    Frost, C.E.2    Yu, Z.3
  • 38
    • 84923220579 scopus 로고    scopus 로고
    • Accessed November 29, 2011
    • European Medicines Agency. Eliquis (apixaban). Product information. http://www.ema.europa.eu/docs/ en-GB/document-library/ EPAR---Product- Information/human/ 002 148/WC500 107 728.pdf. Accessed November 29, 2011.
    • Eliquis (Apixaban). Product Information
  • 39
    • 79952301326 scopus 로고    scopus 로고
    • Apixaban in patients with atrial fibrillation
    • AVERROES Steering Committee and Investigators
    • Connolly SJ, Eikelboom J, Joyner C, et al.; AVERROES Steering Committee and Investigators. Apixaban in patients with atrial fibrillation. N Engl J Med. 2011; 364: 806-817.
    • (2011) N Engl J Med , vol.364 , pp. 806-817
    • Connolly, S.J.1    Eikelboom, J.2    Joyner, C.3
  • 40
    • 76749163232 scopus 로고    scopus 로고
    • Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach: The Euro Heart Survey on atrial fibrillation
    • Lip GY, Nieuwlaat R, Pisters R, et al. Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach: the Euro Heart Survey on atrial fibrillation. Chest. 2010; 137: 263-272.
    • (2010) Chest , vol.137 , pp. 263-272
    • Lip, G.Y.1    Nieuwlaat, R.2    Pisters, R.3
  • 41
    • 77955872745 scopus 로고    scopus 로고
    • A novel user-friendly score (HAS-BLED) to assess 1-year risk of major bleeding in patients with atrial fibrillation: The Euro Heart Survey
    • Pisters R, Lane DA, Nieuwlaat R, et al. A novel user-friendly score (HAS-BLED) to assess 1-year risk of major bleeding in patients with atrial fibrillation: the Euro Heart Survey. Chest. 2010; 138: 1093-1100.
    • (2010) Chest , vol.138 , pp. 1093-1100
    • Pisters, R.1    Lane, D.A.2    Nieuwlaat, R.3
  • 42
    • 79953901937 scopus 로고    scopus 로고
    • What do the RE-LY, AVERROES and ROCKET-AF trials tell us for stroke prevention in atrial fibrillation?
    • Ahrens I, Lip GY, Peter K. What do the RE-LY, AVERROES and ROCKET-AF trials tell us for stroke prevention in atrial fibrillation? Thromb Haemost. 2011; 105: 574-578.
    • (2011) Thromb Haemost , vol.105 , pp. 574-578
    • Ahrens, I.1    Lip, G.Y.2    Peter, K.3
  • 43
    • 79955439399 scopus 로고    scopus 로고
    • Bleeding risk assessment and management in atrial fibrillation patients: A position document from the European Heart Rhythm Association, endorsed by the European Society of Cardiology Working Group on Thrombosis
    • Lip GY, Andreotti F, Fauchier L, et al. Bleeding risk assessment and management in atrial fibrillation patients: a position document from the European Heart Rhythm Association, endorsed by the European Society of Cardiology Working Group on Thrombosis. Europace. 2011; 13: 723-746.
    • (2011) Europace , vol.13 , pp. 723-746
    • Lip, G.Y.1    Andreotti, F.2    Fauchier, L.3
  • 44
    • 77953851760 scopus 로고    scopus 로고
    • Underuse of oral anticoagulants in atrial fibrillation: A systematic review
    • Ogilvie IM, Newton N, Welner SA, et al. Underuse of oral anticoagulants in atrial fibrillation: a systematic review. Am J Med. 2010; 123: 638-645.e4.
    • (2010) Am J Med , vol.123
    • Ogilvie, I.M.1    Newton, N.2    Welner, S.A.3
  • 45
    • 77956229745 scopus 로고    scopus 로고
    • Does warfarin for stroke thromboprophylaxis protect against MI in atrial fibrillation patients?
    • Lip GY, Lane DA. Does warfarin for stroke thromboprophylaxis protect against MI in atrial fibrillation patients? Am J Med. 2010; 123: 785-789.
    • (2010) Am J Med , vol.123 , pp. 785-789
    • Lip, G.Y.1    Lane, D.A.2
  • 46
    • 74249099911 scopus 로고    scopus 로고
    • Management of antithrombotic therapy in atrial fibrillation patients presenting with acute coronary syndrome and/or undergoing percutaneous coronary intervention/stenting
    • European Society of Cardiology Working Group on Thrombosis
    • Lip GY, Huber K, Andreotti F, et al.; European Society of Cardiology Working Group on Thrombosis. Management of antithrombotic therapy in atrial fibrillation patients presenting with acute coronary syndrome and/or undergoing percutaneous coronary intervention/stenting. Thromb Haemost. 2010; 103: 13-28.
    • (2010) Thromb Haemost , vol.103 , pp. 13-28
    • Lip, G.Y.1    Huber, K.2    Andreotti, F.3
  • 47
    • 80053177375 scopus 로고    scopus 로고
    • Consensus document: Antithrombotic therapy in patients with atrial fibrillation undergoing coronary stenting. A North-American perspective
    • Faxon DP, Eikelboom JW, Berger PB, et al. Consensus document: antithrombotic therapy in patients with atrial fibrillation undergoing coronary stenting. A North-American perspective. Thromb Haemost. 2011; 106: 572-584.
    • (2011) Thromb Haemost , vol.106 , pp. 572-584
    • Faxon, D.P.1    Eikelboom, J.W.2    Berger, P.B.3
  • 48
    • 80053207003 scopus 로고    scopus 로고
    • Antithrombotic therapy in patients with atrial fibrillation undergoing coronary stenting: Similarities and dissimilarities between North America and Europe
    • Huber K, Airaksinen KJ, Cuisset T, et al. Antithrombotic therapy in patients with atrial fibrillation undergoing coronary stenting: similarities and dissimilarities between North America and Europe. Thromb Haemost. 2011; 106: 569-571.
    • (2011) Thromb Haemost , vol.106 , pp. 569-571
    • Huber, K.1    Airaksinen, K.J.2    Cuisset, T.3
  • 49
    • 79955774273 scopus 로고    scopus 로고
    • Cost-effectiveness of dabigatran etexilate for the prevention of stroke and systemic embolism in atrial fibrillation: A Canadian payer perspective
    • Sorensen SV, Kansal AR, Connolly S, et al. Cost-effectiveness of dabigatran etexilate for the prevention of stroke and systemic embolism in atrial fibrillation: a Canadian payer perspective. Thromb Haemost. 2011; 105: 908-919.
    • (2011) Thromb Haemost , vol.105 , pp. 908-919
    • Sorensen, S.V.1    Kansal, A.R.2    Connolly, S.3
  • 50
    • 79551589662 scopus 로고    scopus 로고
    • Cost-effectiveness of dabigatran compared with warfarin for stroke prevention in atrial fibrillation
    • Freeman JV, Zhu RP, Owens DK, et al. Cost-effectiveness of dabigatran compared with warfarin for stroke prevention in atrial fibrillation. Ann Intern Med. 2011; 154: 1-11.
    • (2011) Ann Intern Med , vol.154 , pp. 1-11
    • Freeman, J.V.1    Zhu, R.P.2    Owens, D.K.3


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