Deviations from evidence-based clinical management guidelines increase mortality in critically injured trauma patients*

Critical Care Medicine

Volumn 40, Issue 3, 2012, Pages 778-786

  Rice, Todd W ^a   Morris, Stephen ^b   Tortella, Bartholomew J ^c   Wheeler, Arthur P ^a   Christensen, Michael C ^d  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c NOVO NORDISK INC   (United States)

^d NOVO NORDISK A S   (Denmark)

Author keywords

blood transfusion; clinical guidelines; damage control; hemorrhage; mechanical ventilation; mortality; trauma

Indexed keywords

PLACEBO; RECOMBINANT BLOOD CLOTTING FACTOR 7A;

ADULT; AGED; ARTICLE; ARTIFICIAL VENTILATION; BLOOD TRANSFUSION; BLUNT TRAUMA; CONTROLLED STUDY; CRITICALLY ILL PATIENT; DOUBLE BLIND PROCEDURE; EVIDENCE BASED PRACTICE; HUMAN; INTENSIVE CARE; MAJOR CLINICAL STUDY; MORTALITY; MULTICENTER STUDY; OUTCOME ASSESSMENT; PENETRATING TRAUMA; PRACTICE GUIDELINE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADULT; DOUBLE-BLIND METHOD; EVIDENCE-BASED MEDICINE; FEMALE; GUIDELINE ADHERENCE; HUMANS; INJURY SEVERITY SCORE; MALE; PROSPECTIVE STUDIES; WOUNDS AND INJURIES;

EID: 84857514898     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e318236f168     Document Type: Article

References (31)

1. Morris AH: Rational use of computerized protocols in the intensive care unit. Crit Care 2001;5:249-254
2. ATLS, Advanced Trauma Life Support. Program for Doctors, Seventh Edition, Chicago, IL, American College of Surgeons, 2004
3. van den Berghe G, Wouters P, Weekers F, et al: Intensive insulin therapy in the critically ill patients. N Engl J Med 2001;345:1359-1367
4. Van den Berghe G, Wilmer A, Hermans G, et al: Intensive insulin therapy in the medical ICU. N Engl J Med 2006;354:449-461
5. Napolitano LM: Current status of blood component therapy in surgical critical care. Curr Opin Crit Care 2004;10:311-317
6. Corwin HL, Gettinger A, Pearl RG, et al: The CRIT Study: Anemia and blood transfusion in the critically ill-current clinical practice in the United States. Crit Care Med 2004;32:39-52
7. Rivers E, Nguyen B, Havstad S, et al: Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001;345:1368-1377
8. National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network, Wiedemann HP, Wheeler AP, et al: Comparison of two fluidmanagement strategies in acute lung injury. N Engl J Med 2006;354:2564-2575
9. Kress JP, Pohlman AS, O'Connor MF, et al: Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation. N Engl J Med 2000;342:1471-1477
10. Ely EW, Baker AM, Dunagan DP, et al: Effect on the duration of mechanical ventilation of identifying patients capable of breathing spontaneously. N Engl J Med 1996;335:1864-1869
11. Girard TD, Kress JP, Fuchs BD, et al: Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled Trial): A randomised controlled trial. Lancet 2008;371:126-134
12. The Acute Respiratory Distress Syndrome Network: Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 2000;342:1301-1308
13. Rice TW, Wheeler AP, Bernard GR, et al: A randomized, double-blind, placebo-controlled trial of TAK-242 for the treatment of severe sepsis. Crit Care Med 2010;38:1685-1694
14. Rice TW, Thompson BT, Smoot E, et al: Omega-3 (N-3) fatty acid, gamma-linolenic acid (GLA) and anti-oxidant supplementation in acute lung injury (OMEGA Trial). Crit Care Med 2009;37(12 Suppl):A408
15. Stelfox HT, Straus SE, Nathens A, et al: Evidence for quality indicators to evaluate adult trauma care: A systematic review. Crit Care Med 2011;39:846-859
16. Hauser CJ, Boffard K, Dutton R, et al: Results of the CONTROL trial: efficacy and safety of recombinant activated Factor VII in the management of refractory traumatic hemorrhage. J Trauma 2010;69:489-500
17. Rotondo MF, Zonies DH: The damage control sequence and underlying logic. Surg Clin North Am 1997;77:761-777
18. Schoenfeld DA, Bernard GR, ARDS Network: Statistical evaluation of ventilator-free days as an efficacy measure in clinical trials of treatments for acute respiratory distress syndrome. Crit Care Med 2002;30:1772-1777
19. Ferreira FL, Bota DP, Bross A, et al: Serial evaluation of the SOFA score to predict outcome in critically ill patients. JAMA 2001;286:1754-1758
20. Rizoli SB, Nascimento B Jr, Osman F, et al: Recombinant activated coagulation factor VII and bleeding trauma patients. J Trauma 2006;61:1419-1425
21. Wafaisade A, Wutzler S, Lefering R, et al: Drivers of acute coagulopathy after severe trauma: A multivariate analysis of 1987 patients. Emerg Med J 2010;27:934-939
22. Bernard GR, Vincent JL, Laterre PF, et al: Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 2001;344:699-709
23. Esteban A, Frutos F, Tobin MJ, et al: A comparison of four methods of weaning patients from mechanical ventilation. Spanish Lung Failure Collaborative Group. N Engl J Med 1995;332:345-350
24. Esteban A, Alia I, Tobin MJ, et al: Effect of spontaneous breathing trial duration on outcome of attempts to discontinue mechanical ventilation. Am J Respir Crit Care Med 1999;159:512-518
25. Marelich GP, Murin S, Battistella F, et al: Protocol weaning of mechanical ventilation in medical and surgical patients by respiratory care practitioners and nurses: effect on weaning time and incidence of ventilator-associated pneumonia. Chest 2000;118:459-467
26. Yang M, Ahn HJ, Kim K, et al: Does a protective ventilation strategy reduce the risk of pulmonary complications following lung cancer surgery? A randomized controlled trial. Chest 2010; Sept 9 [Epub ahead of print]
27. Determann RM, Royakkers A, Wolthuis EK, et al: Ventilation with lower tidal volumes as compared to conventional tidal volumes for patients without acute lung injury: A preventive randomized controlled trial. Crit Care 2010;14:R1
28. Mascia L, Zavala E, Bosma K, et al: High tidal volume is associated with the development of acute lung injury after severe brain injury: An international observational study. Crit Care Med 2007;35:1815-1820
29. Mion LC, Minnick AF, Leipzig R, et al: Patientinitiated device removal in intensive care units: A national prevalence study. Crit Care Med 2007;35:2714-2720
30. Gurses A, Marsteller J, Ozok A, et al: Using an interdisciplinary approach to identify factors that affect clinicians' compliance with evidencebased guidelines. Crit Care Med 2010;38(Suppl 8): S282-S291
31. Meeks DW, Lally KP, Carrick MM, et al: Compliance with guidelines to prevent surgical site infections: As simple as 1-2-3? Am J Surg 2011;201:76-83