Bistable switch in migration stimulating factor expression: Regulation by the concerted signalling of transforming growth factor-β1 and the extracellular matrix

International Journal of Cancer

Volumn 130, Issue 9, 2012, Pages 2024-2032

  Schor, Seth L ^a   Ellis, Ian R ^a   Jones, Sarah J ^a   Woolston, Anne Marie ^a   Schor, Ana M ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

cancer progression; gene expression; matrix modulation; MSF; TGF

Indexed keywords

COLLAGEN TYPE 1; FIBRIN; MIGRATION STIMULATING FACTOR; PLASTIC; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; ARTICLE; BREAST CARCINOMA; CANCER PATIENT; CELL ADHESION; CELL SURVIVAL; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FEMALE; FETUS; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SKIN FIBROBLAST;

ANIMALS; BREAST NEOPLASMS; CARCINOMA, DUCTAL; CELL MIGRATION ASSAYS; CELLS, CULTURED; COLLAGEN TYPE I; CYTOKINES; EXTRACELLULAR MATRIX; FEMALE; FETAL DEVELOPMENT; FIBRIN; FIBROBLASTS; FIBRONECTINS; GENE EXPRESSION REGULATION; HUMANS; MIDDLE AGED; PROTEIN ISOFORMS; RATS; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84857506158     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.26213     Document Type: Article

References (40)

1. Schor SL, Schor AM, Grey AM, Rushton G,. Fetal and cancer patient fibroblasts produce an autocrine migration stimulating factor not made by normal adult cells. J Cell Sci 1988; 90: 91-9.
2. Schor SL, Ellis IR, Jones SJ, Baillie R, Seneviratne K, Clausen J, Motegi K, Vojtesek B, Kankova K, Furrie E, Sales MJ, Schor AM, et al. Migration-stimulating factor: a genetically truncated onco-fetal fibronectin isoform expressed by carcinoma and tumor-associated stromal cells. Cancer Res 2003; 63: 8827-36.
3. Schor AM, Schor SL,. Angiogenesis and tumour progression: migration-stimulating factor as a novel target for clinical intervention. Eye 2010; 24: 450-8.
4. Hu H, Ran Y, Zhang Y, Zhou Z, Harris SJ, Yu L, Sun L, Pan J, Liu J, Lou J, Yang Z,. Antibody library-based tumour endothelial cells surface proteomic functional screen reveals migration-stimulating factor as an anti-angiogenic target. Mol Cell Proteomics 2009; 8: 816-26.
5. Houard X, Germain S, Gervais M, Michaud A, van den Brule F, Foidart J-M, Noel A, Monnot C, Corvol P,. Migration-stimulating factor displays HEXXH-dependent catalytic activity important for promoting tumor cell migration. Int J Cancer 2005; 116: 378-84.
6. Schor SL, Schor AM, Rushton G, Smith L,. Adult, foetal, and transformed fibroblasts display different migratory phenotypes on collagen gels: evidence for an isoformic transition during foetal development. J Cell Sci 1985; 73: 221-34.
7. Schor SL, Schor AM, Durning P, Rushton G,. Skin fibroblasts obtained from cancer patients display a fetal-like migratory behaviour on collagen gels. J Cell Sci 1985; 73: 235-44.
8. Schor SL, Haggie J, Durning P, Howell A, Sellwood RAS, Crowther D,. The occurrence of a foetal fibroblast phenotype in familial breast cancer. Int J Cancer 1986; 37: 831-6.
9. Schor SL, Schor AM, Rushton G,. Fibroblasts from cancer patients display a mixture of both foetal and adult phenotypic characteristics. J Cell Sci 1988; 90: 401-7.
10. Hynes R,. Fibronectins. New York: Springer-Verlag, 1990.
11. Kay RA, Ellis IR, Jones SJ, Perrier S, Florence MM, Schor AM, Schor SL,. The expression of MSF, a potent oncofetal cytokine, is uniquely controlled by 3â€-untranslated region dependent nuclear sequestration of its precursor messenger RNA. Cancer Res 2005; 65: 10742-9.
12. Schor SL, Schor AM,. Tumour-stroma interactions. Phenotypic and genetic alterations in mammary stroma: implications for tumour progression. Breast Cancer Res 2001; 3: 373-9.
13. Schor AM, Schor SL,. The local and systemic contribution of fibroblast-produced MSF to cancer progression: a novel target for therapeutic intervention. In:, Fusenig N, Mueller M, eds. Tumor-associated fibroblasts and their matrix, Springer Verlag, Heidelberg, Germany, 2011.
14. Durning P, Schor SL, Sellwood RAS,. Fibroblasts from patients with breast cancer show abnormal migratory behaviour in vitro. Lancet 1984; 2: 890-2.
15. Schor AM, Rushton G, Ferguson JE, Howell A, Redford J, Schor SL,. Phenotypic heterogeneity in breast fibroblasts: functional anomaly in fibroblasts from histologically normal tissue adjacent to carcinoma. Int J Cancer 1994; 59: 25-32.
16. Schor SL, Schor AM,. Stromal acceleration of tumour progression: role of "fetal-like" fibroblast subpopulations. Pathol Update 1997; 4: 75-95.
17. Schor SL,. Cell proliferation and migration within three-dimensional collagen gels. J Cell Sci 1980; 41: 159-75.
18. Schor SL, Court J,. Different mechanisms involved in the attachment of cells to native and denatured collagen. J Cell Sci 1979; 38: 267-81.
19. Huang Y-C, Dennis RG, Larkin L, Baar K,. Rapid formation of functional muscle in vitro using fibrin gels. J Appl Physiol 2005; 98: 706-13.
20. Grey AM, Schor AM, Rushton G, Ellis I, Schor SL,. Purification of the migration stimulating factor produced by fetal and cancer patient fibroblasts. Proc Natl Acad Sci USA 1989; 86: 2438-442.
21. Schor SL,. Cytokine control of cell motility: modulation and mediation by the extracellular matrix. Prog Growth Factor Res 1994; 5: 223-48.
22. Schor SL, Ellis I, Grey AM, Dolman C, Banyard J, Humphries MJ, Mosher DE, Sotille J, Mould AP,. Substratum-dependent stimulation of fibroblast migration by the gelatin-binding domain of fibronectin. J Cell Sci 1996; 109: 2581-90.
23. Schor SL, Ellis I, Banyard J, Schor AM,. Motogenic activity of the IGD amino acid motif. J Cell Sci 1999; 112: 3879-88.
24. Schor SL, Schor AM, Keatch RP, Belch JJF,. Role of matrix macromolecules in the aetiology and treatment of chronic ulcers. In:, Lee BY, ed. The wound management manual. New York: McGraw Hill, 2005. 109-21.
25. Nathan C, Sporn M,. Cytokines in context. J Cell Biol 1991; 113: 981-6.
26. Padua D, Massague J,. Role of TGF-β in metastasis. Cell Res 2009; 19: 89-102.
27. Pardali E, ten Dijke P,. Transforming growth factor-beta signaling and tumor angiogenesis. Front Biosci 2009; 14: 4848-61.
28. Xu R, Boudreau A, Bissell MJ,. Tissue architecture and function: dynamic reciprocity via extra- and intra-cellular matrices. Cancer Metastasis Rev 2009; 28: 167-76.
29. Jaenisch R, Bird A,. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet (Suppl) 2003; 33: 245-54.
30. D'Alessio AC, Szyf M,. Epigenetic tete-a-tete: the bilateral relationship between chromatin modifications and DNA methylation. Biochem Cell Biol 2006; 84: 463-76.
31. Ting AH, McGarvey KM, Baylin SB,. The cancer epigenomeâ€" components and functional correlates. Genes Dev 2006; 20: 3215-31.
32. Lim HN, van Oudenaarden A,. A multistep epigenetic switch enables the stable inheritance of DNA methylation states. Nat Genet 2007; 39: 269-75.
33. Shirai T, Miyagi S, Horiuchi D, Okuda-Katayanagi T, Nishimoto M, Muramatsu M, Sakamoto Y, Nagata M, Hagiwara K, Okuda A,. Identification of an enhancer that controls up-regulation of fibronectin during differentiation of embryonic stem cells into extraembryonic endoderm. J Biol Chem 2005; 280: 7244-52.
34. Schor SL, Schor AM, Ellis IR, Jones SJ, Florence MM, Cox J, Woolston AM,. The oncofetal paradigm revisited: MSF and HA as contextual drivers of cancer progression. In:, Stern R, ed. Hyaluronan in cancer biology. Academic Press, San Diego, USA, 2009; 285-306.
35. Bierie B, Moses HL,. TGF-beta and cancer. Cytokine Growth Factor Rev 2006; 17: 29-40.
36. Yoshino I, Kometani T, Shoji F, Osoegawa A, Ohba T, Kouso H, Takenaka T, Yohena T, Maehara Y,. Induction of epithelial-mesenchymal transition-related genes by benzo[a]pyrene in lung cancer cells. Cancer 2007; 110: 369-74.
37. Nielsen M, Thomsen JL, Primdahl S, Dyreborg U, Andersen JA,. Breast cancer and atypia among young and middle-aged women. Br J Cancer 1987; 56: 814-9.
38. Schor SL, Schor AM, Howell A, Crowther D,. Hypothesis: persistent expression of fetal phenotypic characteristics by fibroblasts is associated with an increased susceptibility to neoplastic disease. Exp Cell Biol 1987; 55: 11-7.
39. Feinberg AP, Ohlsson R, Henikoff S,. The epigenetic progenitor origin of human cancer. Nat Rev Genet 2006; 7: 21-33.
40. Aharinejad S, Sioud M, Lucas T, Abraham D,. Targeting stromal-cancer cell interactions with siRNAs. Methods Mol Biol 2009; 487: 243-66.