-
1
-
-
60749137451
-
Beyond chemotherapy: Targeted therapies in ovarian cancer
-
Yap TA, Carden CP, Kaye SB,. Beyond chemotherapy: targeted therapies in ovarian cancer. Nat Rev Cancer 2009; 9: 167-81.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 167-181
-
-
Yap, T.A.1
Carden, C.P.2
Kaye, S.B.3
-
2
-
-
0344825356
-
P-glycoprotein: From genomics to mechanism
-
Ambudkar SV, Kimchi-Sarfaty C, Sauna ZE, Gottesman MM,. P-glycoprotein: from genomics to mechanism. Oncogene 2003; 22: 7468-85.
-
(2003)
Oncogene
, vol.22
, pp. 7468-7485
-
-
Ambudkar, S.V.1
Kimchi-Sarfaty, C.2
Sauna, Z.E.3
Gottesman, M.M.4
-
3
-
-
47349110179
-
Structure, function and regulation of P-glycoprotein and its clinical relevance in drug disposition
-
Zhou SF,. Structure, function and regulation of P-glycoprotein and its clinical relevance in drug disposition. Xenobiotica 2008; 38: 802-32.
-
(2008)
Xenobiotica
, vol.38
, pp. 802-832
-
-
Zhou, S.F.1
-
4
-
-
58249088751
-
MicroRNAs: Target recognition and regulatory functions
-
Bartel DP,. MicroRNAs: target recognition and regulatory functions. Cell 2009; 136: 215-33.
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
5
-
-
77449133843
-
The role of let-7 in cell differentiation and cancer
-
Boyerinas B, Park SM, Hau A, Murmann AE, Peter ME,. The role of let-7 in cell differentiation and cancer. Endocr Relat Cancer 2010; 17: F19-36.
-
(2010)
Endocr Relat Cancer
, vol.17
-
-
Boyerinas, B.1
Park, S.M.2
Hau, A.3
Murmann, A.E.4
Peter, M.E.5
-
6
-
-
66849140943
-
MicroRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agents
-
Cochrane DR, Spoelstra NS, Howe EN, Nordeen SK, Richer JK,. MicroRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agents. Mol Cancer Ther 2009; 8: 1055-66.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 1055-1066
-
-
Cochrane, D.R.1
Spoelstra, N.S.2
Howe, E.N.3
Nordeen, S.K.4
Richer, J.K.5
-
7
-
-
34548059198
-
A miR-24 microRNA binding-site polymorphism in dihydrofolate reductase gene leads to methotrexate resistance
-
Mishra PJ, Humeniuk R, Longo-Sorbello GS, Banerjee D, Bertino JR,. A miR-24 microRNA binding-site polymorphism in dihydrofolate reductase gene leads to methotrexate resistance. Proc Natl Acad Sci USA 2007; 104: 13513-8.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 13513-13518
-
-
Mishra, P.J.1
Humeniuk, R.2
Longo-Sorbello, G.S.3
Banerjee, D.4
Bertino, J.R.5
-
8
-
-
49149114863
-
Role of microRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells
-
Zhu H, Wu H, Liu X, Evans BR, Medina DJ, Liu CG, Yang JM,. Role of microRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells. Biochem Pharmacol 2008; 76: 582-8.
-
(2008)
Biochem Pharmacol
, vol.76
, pp. 582-588
-
-
Zhu, H.1
Wu, H.2
Liu, X.3
Evans, B.R.4
Medina, D.J.5
Liu, C.G.6
Yang, J.M.7
-
9
-
-
66849113786
-
MicroRNA-328 negatively regulates the expression of breast cancer resistance protein (BCRP/ABCG2) in human cancer cells
-
Pan YZ, Morris ME, Yu AM,. MicroRNA-328 negatively regulates the expression of breast cancer resistance protein (BCRP/ABCG2) in human cancer cells. Mol Pharmacol 2009; 75: 1374-9.
-
(2009)
Mol Pharmacol
, vol.75
, pp. 1374-1379
-
-
Pan, Y.Z.1
Morris, M.E.2
Yu, A.M.3
-
10
-
-
50249188925
-
Regulation of ABCG2 expression at the 3†untranslated region of its mRNA through modulation of transcript stability and protein translation by a putative microRNA in the S1 colon cancer cell line
-
To KK, Zhan Z, Litman T, Bates SE,. Regulation of ABCG2 expression at the 3†untranslated region of its mRNA through modulation of transcript stability and protein translation by a putative microRNA in the S1 colon cancer cell line. Mol Cell Biol 2008; 28: 5147-61.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 5147-5161
-
-
To, K.K.1
Zhan, Z.2
Litman, T.3
Bates, S.E.4
-
11
-
-
36849078711
-
Let-7 regulates self renewal and tumorigenicity of breast cancer cells
-
Yu F, Yao H, Zhu P, Zhang X, Pan Q, Gong C, Huang Y, Hu X, Su F, Lieberman J, Song E,. Let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell 2007; 131: 1109-23.
-
(2007)
Cell
, vol.131
, pp. 1109-1123
-
-
Yu, F.1
Yao, H.2
Zhu, P.3
Zhang, X.4
Pan, Q.5
Gong, C.6
Huang, Y.7
Hu, X.8
Su, F.9
Lieberman, J.10
Song, E.11
-
12
-
-
77955632689
-
Systematic analysis of microRNA involved in resistance of the MCF-7 human breast cancer cell to doxorubicin
-
Chen GQ, Zhao ZW, Zhou HY, Liu YJ, Yang HJ,. Systematic analysis of microRNA involved in resistance of the MCF-7 human breast cancer cell to doxorubicin. Med Oncol 2009; 27: 406-15.
-
(2009)
Med Oncol
, vol.27
, pp. 406-415
-
-
Chen, G.Q.1
Zhao, Z.W.2
Zhou, H.Y.3
Liu, Y.J.4
Yang, H.J.5
-
13
-
-
38349190243
-
MicroRNAs modulate the chemosensitivity of tumor cells
-
Blower PE, Chung JH, Verducci JS, Lin S, Park JK, Dai Z, Liu CG, Schmittgen TD, Reinhold WC, Croce CM, Weinstein JN, Sadee W,. MicroRNAs modulate the chemosensitivity of tumor cells. Mol Cancer Ther 2008; 7: 1-9.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 1-9
-
-
Blower, P.E.1
Chung, J.H.2
Verducci, J.S.3
Lin, S.4
Park, J.K.5
Dai, Z.6
Liu, C.G.7
Schmittgen, T.D.8
Reinhold, W.C.9
Croce, C.M.10
Weinstein, J.N.11
Sadee, W.12
-
14
-
-
37049019490
-
MicroRNAs as potential agents to alter resistance to cytotoxic anticancer therapy
-
Weidhaas JB, Babar I, Nallur SM, Trang P, Roush S, Boehm M, Gillespie E, Slack FJ,. MicroRNAs as potential agents to alter resistance to cytotoxic anticancer therapy. Cancer Res 2007; 67: 11111-6.
-
(2007)
Cancer Res
, vol.67
, pp. 11111-11116
-
-
Weidhaas, J.B.1
Babar, I.2
Nallur, S.M.3
Trang, P.4
Roush, S.5
Boehm, M.6
Gillespie, E.7
Slack, F.J.8
-
15
-
-
57749105325
-
MicroRNA microarray identifies Let-7i as a novel biomarker and therapeutic target in human epithelial ovarian cancer
-
Yang N, Kaur S, Volinia S, Greshock J, Lassus H, Hasegawa K, Liang S, Leminen A, Deng S, Smith L, Johnstone CN, Chen XM, et al. MicroRNA microarray identifies Let-7i as a novel biomarker and therapeutic target in human epithelial ovarian cancer. Cancer Res 2008; 68: 10307-14.
-
(2008)
Cancer Res
, vol.68
, pp. 10307-10314
-
-
Yang, N.1
Kaur, S.2
Volinia, S.3
Greshock, J.4
Lassus, H.5
Hasegawa, K.6
Liang, S.7
Leminen, A.8
Deng, S.9
Smith, L.10
Johnstone, C.N.11
Chen, X.M.12
-
16
-
-
41649096450
-
Identification of let-7-regulated oncofetal genes
-
Boyerinas B, Park SM, Shomron N, Hedegaard MM, Vinther J, Andersen JS, Feig C, Xu J, Burge CB, Peter ME,. Identification of let-7-regulated oncofetal genes. Cancer Res 2008; 68: 2587-91.
-
(2008)
Cancer Res
, vol.68
, pp. 2587-2591
-
-
Boyerinas, B.1
Park, S.M.2
Shomron, N.3
Hedegaard, M.M.4
Vinther, J.5
Andersen, J.S.6
Feig, C.7
Xu, J.8
Burge, C.B.9
Peter, M.E.10
-
17
-
-
2042431248
-
The insulin-like growth factor mRNA binding-protein IMP-1 and the Ras-regulatory protein G3BP associate with tau mRNA and HuD protein in differentiated P19 neuronal cells
-
Atlas R, Behar L, Elliott E, Ginzburg I,. The insulin-like growth factor mRNA binding-protein IMP-1 and the Ras-regulatory protein G3BP associate with tau mRNA and HuD protein in differentiated P19 neuronal cells. J Neurochem 2004; 89: 613-26.
-
(2004)
J Neurochem
, vol.89
, pp. 613-626
-
-
Atlas, R.1
Behar, L.2
Elliott, E.3
Ginzburg, I.4
-
18
-
-
0026507321
-
Control of c-myc mRNA half-life in vitro by a protein capable of binding to a coding region stability determinant
-
Bernstein PL, Herrick DJ, Prokipcak RD, Ross J,. Control of c-myc mRNA half-life in vitro by a protein capable of binding to a coding region stability determinant. Genes Dev 1992; 6: 642-54.
-
(1992)
Genes Dev
, vol.6
, pp. 642-654
-
-
Bernstein, P.L.1
Herrick, D.J.2
Prokipcak, R.D.3
Ross, J.4
-
19
-
-
0032533776
-
The c-myc coding region determinant-binding protein: A member of a family of KH domain RNA-binding proteins
-
Doyle GA, Betz NA, Leeds PF, Fleisig AJ, Prokipcak RD, Ross J,. The c-myc coding region determinant-binding protein: a member of a family of KH domain RNA-binding proteins. Nucleic Acids Res 1998; 26: 5036-44.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 5036-5044
-
-
Doyle, G.A.1
Betz, N.A.2
Leeds, P.F.3
Fleisig, A.J.4
Prokipcak, R.D.5
Ross, J.6
-
20
-
-
0031000553
-
Developmental regulation of CRD-BP, an RNA-binding protein that stabilizes c-myc mRNA in vitro
-
Leeds P, Kren BT, Boylan JM, Betz NA, Steer CJ, Gruppuso PA, Ross J,. Developmental regulation of CRD-BP, an RNA-binding protein that stabilizes c-myc mRNA in vitro. Oncogene 1997; 14: 1279-86.
-
(1997)
Oncogene
, vol.14
, pp. 1279-1286
-
-
Leeds, P.1
Kren, B.T.2
Boylan, J.M.3
Betz, N.A.4
Steer, C.J.5
Gruppuso, P.A.6
Ross, J.7
-
22
-
-
33745225167
-
CRD-BP mediates stabilization of betaTrCP1 and c-myc mRNA in response to beta-catenin signalling
-
Noubissi FK, Elcheva I, Bhatia N, Shakoori A, Ougolkov A, Liu J, Minamoto T, Ross J, Fuchs SY, Spiegelman VS,. CRD-BP mediates stabilization of betaTrCP1 and c-myc mRNA in response to beta-catenin signalling. Nature 2006; 441: 898-901.
-
(2006)
Nature
, vol.441
, pp. 898-901
-
-
Noubissi, F.K.1
Elcheva, I.2
Bhatia, N.3
Shakoori, A.4
Ougolkov, A.5
Liu, J.6
Minamoto, T.7
Ross, J.8
Fuchs, S.Y.9
Spiegelman, V.S.10
-
23
-
-
0028245042
-
Purification and properties of a protein that binds to the C-terminal coding region of human c-myc mRNA
-
Prokipcak RD, Herrick DJ, Ross J,. Purification and properties of a protein that binds to the C-terminal coding region of human c-myc mRNA. J Biol Chem 1994; 269: 9261-9.
-
(1994)
J Biol Chem
, vol.269
, pp. 9261-9269
-
-
Prokipcak, R.D.1
Herrick, D.J.2
Ross, J.3
-
24
-
-
4444285375
-
Visualization of RNA-protein interactions in living cells: FMRP and IMP1 interact on mRNAs
-
Rackham O, Brown CM,. Visualization of RNA-protein interactions in living cells: FMRP and IMP1 interact on mRNAs. EMBO J 2004; 23: 3346-55.
-
(2004)
EMBO J
, vol.23
, pp. 3346-3355
-
-
Rackham, O.1
Brown, C.M.2
-
25
-
-
0034703070
-
H19 RNA binds four molecules of insulin-like growth factor II mRNA-binding protein
-
Runge S, Nielsen FC, Nielsen J, Lykke-Andersen J, Wewer UM, Christiansen J,. H19 RNA binds four molecules of insulin-like growth factor II mRNA-binding protein. J Biol Chem 2000; 275: 29562-9.
-
(2000)
J Biol Chem
, vol.275
, pp. 29562-29569
-
-
Runge, S.1
Nielsen, F.C.2
Nielsen, J.3
Lykke-Andersen, J.4
Wewer, U.M.5
Christiansen, J.6
-
26
-
-
34047188544
-
CRD-BP shields c-myc and MDR-1 RNA from endonucleolytic attack by a mammalian endoribonuclease
-
Sparanese D, Lee CH,. CRD-BP shields c-myc and MDR-1 RNA from endonucleolytic attack by a mammalian endoribonuclease. Nucleic Acids Res 2007; 35: 1209-21.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 1209-1221
-
-
Sparanese, D.1
Lee, C.H.2
-
27
-
-
33645729341
-
RNA-binding IMPs promote cell adhesion and invadopodia formation
-
Vikesaa J, Hansen TV, Jonson L, Borup R, Wewer UM, Christiansen J, Nielsen FC,. RNA-binding IMPs promote cell adhesion and invadopodia formation. EMBO J 2006; 25: 1456-68.
-
(2006)
EMBO J
, vol.25
, pp. 1456-1468
-
-
Vikesaa, J.1
Hansen, T.V.2
Jonson, L.3
Borup, R.4
Wewer, U.M.5
Christiansen, J.6
Nielsen, F.C.7
-
28
-
-
33847746580
-
C-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion
-
Sawada K, Radjabi AR, Shinomiya N, Kistner E, Kenny HA, Salgia R, Yamada SD, Vande Woude GF, Tretiakova MS, Lengyel E,. C-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion. Cancer Res 2007; 67: 1670-80.
-
(2007)
Cancer Res
, vol.67
, pp. 1670-1680
-
-
Sawada, K.1
Radjabi, A.R.2
Shinomiya, N.3
Kistner, E.4
Kenny, H.A.5
Salgia, R.6
Yamada, S.D.7
Vande Woude, G.F.8
Tretiakova, M.S.9
Lengyel, E.10
-
29
-
-
55649106336
-
Does equal treatment yield equal outcomes? the impact of race on survival in epithelial ovarian cancer
-
Terplan M, Temkin S, Tergas A, Lengyel E,. Does equal treatment yield equal outcomes? The impact of race on survival in epithelial ovarian cancer. Gynecol Oncol 2008; 111: 173-8.
-
(2008)
Gynecol Oncol
, vol.111
, pp. 173-178
-
-
Terplan, M.1
Temkin, S.2
Tergas, A.3
Lengyel, E.4
-
30
-
-
36749086451
-
Expression of the RNA-binding protein IMP1 correlates with poor prognosis in ovarian carcinoma
-
Kobel M, Weidensdorfer D, Reinke C, Lederer M, Schmitt WD, Zeng K, Thomssen C, Hauptmann S, Huttelmaier S,. Expression of the RNA-binding protein IMP1 correlates with poor prognosis in ovarian carcinoma. Oncogene 2007; 26: 7584-89.
-
(2007)
Oncogene
, vol.26
, pp. 7584-7589
-
-
Kobel, M.1
Weidensdorfer, D.2
Reinke, C.3
Lederer, M.4
Schmitt, W.D.5
Zeng, K.6
Thomssen, C.7
Hauptmann, S.8
Huttelmaier, S.9
-
31
-
-
84952094529
-
Detection of influential observations in linear regression
-
Cook RD,. Detection of influential observations in linear regression. Technometrics 1977; 19: 15-18.
-
(1977)
Technometrics
, vol.19
, pp. 15-18
-
-
Cook, R.D.1
-
32
-
-
78349312100
-
Robust one-day in situ hybridization protocol for detection of microRNAs in paraffin samples using LNA probes
-
Jorgensen S, Baker A, Moller S, Nielsen BS,. Robust one-day in situ hybridization protocol for detection of microRNAs in paraffin samples using LNA probes. Methods 2010; 52: 375-81.
-
(2010)
Methods
, vol.52
, pp. 375-381
-
-
Jorgensen, S.1
Baker, A.2
Moller, S.3
Nielsen, B.S.4
-
33
-
-
47949100595
-
Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing
-
Newman MA, Thomson JM, Hammond SM,. Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing. RNA 2008; 14: 1539-49.
-
(2008)
RNA
, vol.14
, pp. 1539-1549
-
-
Newman, M.A.1
Thomson, J.M.2
Hammond, S.M.3
-
34
-
-
40849108663
-
Selective blockade of microRNA processing by Lin28
-
Viswanathan SR, Daley GQ, Gregory RI,. Selective blockade of microRNA processing by Lin28. Science 2008; 320: 97-100.
-
(2008)
Science
, vol.320
, pp. 97-100
-
-
Viswanathan, S.R.1
Daley, G.Q.2
Gregory, R.I.3
-
35
-
-
0031864247
-
Pgp and MRP activities using calcein-AM are prognostic factors in adult acute myeloid leukemia patients
-
Legrand O, Simonin G, Perrot JY, Zittoun R, Marie JP,. Pgp and MRP activities using calcein-AM are prognostic factors in adult acute myeloid leukemia patients. Blood 1998; 91: 4480-8.
-
(1998)
Blood
, vol.91
, pp. 4480-4488
-
-
Legrand, O.1
Simonin, G.2
Perrot, J.Y.3
Zittoun, R.4
Marie, J.P.5
-
36
-
-
34547616150
-
Modulation of the cellular accumulation and intracellular activity of daptomycin towards phagocytized Staphylococcus aureus by the P-glycoprotein (MDR1) efflux transporter in human THP-1 macrophages and madin-darby canine kidney cells
-
Lemaire S, Van Bambeke F, Mingeot-Leclercq MP, Tulkens PM,. Modulation of the cellular accumulation and intracellular activity of daptomycin towards phagocytized Staphylococcus aureus by the P-glycoprotein (MDR1) efflux transporter in human THP-1 macrophages and madin-darby canine kidney cells. Antimicrob Agents Chemother 2007; 51: 2748-57.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 2748-2757
-
-
Lemaire, S.1
Van Bambeke, F.2
Mingeot-Leclercq, M.P.3
Tulkens, P.M.4
-
37
-
-
0346243995
-
Analysis of P-glycoprotein-mediated membrane transport in human peripheral blood lymphocytes using the UIC2 shift assay
-
Park SW, Lomri N, Simeoni LA, Fruehauf JP, Mechetner E,. Analysis of P-glycoprotein-mediated membrane transport in human peripheral blood lymphocytes using the UIC2 shift assay. Cytometry A 2003; 53: 67-78.
-
(2003)
Cytometry A
, vol.53
, pp. 67-78
-
-
Park, S.W.1
Lomri, N.2
Simeoni, L.A.3
Fruehauf, J.P.4
Mechetner, E.5
-
38
-
-
34547500470
-
Localization of P-glycoprotein at the nuclear envelope of rat brain cells
-
Babakhanian K, Bendayan M, Bendayan R,. Localization of P-glycoprotein at the nuclear envelope of rat brain cells. Biochem Biophys Res Commun 2007; 361: 301-6.
-
(2007)
Biochem Biophys Res Commun
, vol.361
, pp. 301-306
-
-
Babakhanian, K.1
Bendayan, M.2
Bendayan, R.3
-
39
-
-
0347517755
-
Nuclear transit of human zipcode-binding protein IMP1
-
Nielsen J, Adolph SK, Rajpert-De Meyts E, Lykke-Andersen J, Koch G, Christiansen J, Nielsen FC,. Nuclear transit of human zipcode-binding protein IMP1. Biochem J 2003; 376 (Pt 2): 383-91.
-
(2003)
Biochem J
, vol.376
, Issue.PART 2
, pp. 383-391
-
-
Nielsen, J.1
Adolph, S.K.2
Rajpert-De Meyts, E.3
Lykke-Andersen, J.4
Koch, G.5
Christiansen, J.6
Nielsen, F.C.7
-
40
-
-
65649131520
-
Multidrug resistance through the spectacle of P-glycoprotein
-
Goda K, Bacso Z, Szabo G,. Multidrug resistance through the spectacle of P-glycoprotein. Curr Cancer Drug Targets 2009; 9: 281-97.
-
(2009)
Curr Cancer Drug Targets
, vol.9
, pp. 281-297
-
-
Goda, K.1
Bacso, Z.2
Szabo, G.3
-
41
-
-
77951620660
-
The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma
-
Shimizu S, Takehara T, Hikita H, Kodama T, Miyagi T, Hosui A, Tatsumi T, Ishida H, Noda T, Nagano H, Doki Y, Mori M, et al. The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma. J Hepatol 2010; 52: 698-704.
-
(2010)
J Hepatol
, vol.52
, pp. 698-704
-
-
Shimizu, S.1
Takehara, T.2
Hikita, H.3
Kodama, T.4
Miyagi, T.5
Hosui, A.6
Tatsumi, T.7
Ishida, H.8
Noda, T.9
Nagano, H.10
Doki, Y.11
Mori, M.12
-
42
-
-
62149113710
-
Relevance of multidrug resistance in the age of targeted therapy
-
Turk D, Szakacs G,. Relevance of multidrug resistance in the age of targeted therapy. Curr Opin Drug Discov Devel 2009; 12: 246-52.
-
(2009)
Curr Opin Drug Discov Devel
, vol.12
, pp. 246-252
-
-
Turk, D.1
Szakacs, G.2
|