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Volumn 7, Issue 2, 2012, Pages

In vitro maturation of dopaminergic neurons derived from mouse embryonic stem cells: Implications for transplantation

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; AMINO ACID; CALCIUM ION; CHLORIDE ION; GLUTAMIC ACID; NEUROTOXIN; TRANSCRIPTION FACTOR PITX3; TYROSINE 3 MONOOXYGENASE; CATECHOLAMINE; GREEN FLUORESCENT PROTEIN;

EID: 84857491742     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0031999     Document Type: Article
Times cited : (27)

References (51)
  • 1
    • 33947308285 scopus 로고    scopus 로고
    • How is pluripotency determined and maintained?
    • Niwa H, (2007) How is pluripotency determined and maintained? Development 134: 635-646.
    • (2007) Development , vol.134 , pp. 635-646
    • Niwa, H.1
  • 2
    • 34547620338 scopus 로고    scopus 로고
    • Embryonic stem cells as a source of models for drug discovery
    • Pouton CW, Haynes JM, (2007) Embryonic stem cells as a source of models for drug discovery. Nat Rev Drug Discov 6: 605-616.
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 605-616
    • Pouton, C.W.1    Haynes, J.M.2
  • 3
    • 38849125416 scopus 로고    scopus 로고
    • Derive and conquer: sourcing and differentiating stem cells for therapeutic applications
    • Klimanskaya I, Rosenthal N, Lanza R, (2008) Derive and conquer: sourcing and differentiating stem cells for therapeutic applications. Nature Reviews Drug Discovery 7: 131-142.
    • (2008) Nature Reviews Drug Discovery , vol.7 , pp. 131-142
    • Klimanskaya, I.1    Rosenthal, N.2    Lanza, R.3
  • 4
    • 79956212343 scopus 로고    scopus 로고
    • Constructing and deconstructing stem cell models of neurological disease
    • Han SS, Williams LA, Eggan KC, (2011) Constructing and deconstructing stem cell models of neurological disease. Neuron 70: 626-644.
    • (2011) Neuron , vol.70 , pp. 626-644
    • Han, S.S.1    Williams, L.A.2    Eggan, K.C.3
  • 5
    • 0347135824 scopus 로고    scopus 로고
    • Embryonic stem cells in drug discovery
    • McNeish J, (2004) Embryonic stem cells in drug discovery. Nat Rev Drug Discov 3: 70-80.
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 70-80
    • McNeish, J.1
  • 6
    • 37449007532 scopus 로고    scopus 로고
    • From bench to bed: the potential of stem cells for the treatment of Parkinson's disease
    • Morizane A, Li JY, Brundin P, (2008) From bench to bed: the potential of stem cells for the treatment of Parkinson's disease. Cell Tissue Res 331: 323-336.
    • (2008) Cell Tissue Res , vol.331 , pp. 323-336
    • Morizane, A.1    Li, J.Y.2    Brundin, P.3
  • 7
    • 79952245490 scopus 로고    scopus 로고
    • Rewiring the brain with cell transplantation in Parkinson's disease
    • Gaillard A, Jaber M, (2011) Rewiring the brain with cell transplantation in Parkinson's disease. Trends Neurosci.
    • (2011) Trends Neurosci
    • Gaillard, A.1    Jaber, M.2
  • 8
    • 0037226224 scopus 로고    scopus 로고
    • Potential use of embryonic stem cells for the treatment of mouse parkinsonian models: improved behavior by transplantation of in vitro differentiated dopaminergic neurons from embryonic stem cells
    • Nishimura F, Yoshikawa M, Kanda S, Nonaka M, Yokota H, et al. (2003) Potential use of embryonic stem cells for the treatment of mouse parkinsonian models: improved behavior by transplantation of in vitro differentiated dopaminergic neurons from embryonic stem cells. Stem Cells 21: 171-180.
    • (2003) Stem Cells , vol.21 , pp. 171-180
    • Nishimura, F.1    Yoshikawa, M.2    Kanda, S.3    Nonaka, M.4    Yokota, H.5
  • 9
    • 0037133163 scopus 로고    scopus 로고
    • Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model
    • Bjorklund LM, Sanchez-Pernaute R, Chung S, Andersson T, Chen IY, et al. (2002) Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model. Proc Natl Acad Sci U S A 99: 2344-2349.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 2344-2349
    • Bjorklund, L.M.1    Sanchez-Pernaute, R.2    Chung, S.3    Andersson, T.4    Chen, I.Y.5
  • 10
    • 77954932494 scopus 로고    scopus 로고
    • Dopaminergic Neurons Derived from Human Induced Pluripotent Stem Cells Survive and Integrate into 6-OHDA Lesioned Rats
    • Cai J, Yang M, Poremsky E, Kidd S, Schneider JS, et al. (2009) Dopaminergic Neurons Derived from Human Induced Pluripotent Stem Cells Survive and Integrate into 6-OHDA Lesioned Rats. Stem Cells Dev.
    • (2009) Stem Cells Dev
    • Cai, J.1    Yang, M.2    Poremsky, E.3    Kidd, S.4    Schneider, J.S.5
  • 11
    • 67849111372 scopus 로고    scopus 로고
    • Identification of transplantable dopamine neuron precursors at different stages of midbrain neurogenesis
    • Jonsson ME, Ono Y, Bjorklund A, Thompson LH, (2009) Identification of transplantable dopamine neuron precursors at different stages of midbrain neurogenesis. Exp Neurol 219: 341-354.
    • (2009) Exp Neurol , vol.219 , pp. 341-354
    • Jonsson, M.E.1    Ono, Y.2    Bjorklund, A.3    Thompson, L.H.4
  • 12
    • 65849148469 scopus 로고    scopus 로고
    • Survival and early functional integration of dopaminergic progenitor cells following transplantation in a rat model of Parkinson's disease
    • Hahn M, Timmer M, Nikkhah G, (2009) Survival and early functional integration of dopaminergic progenitor cells following transplantation in a rat model of Parkinson's disease. J Neurosci Res 87: 2006-2019.
    • (2009) J Neurosci Res , vol.87 , pp. 2006-2019
    • Hahn, M.1    Timmer, M.2    Nikkhah, G.3
  • 13
    • 33644684826 scopus 로고    scopus 로고
    • Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats
    • Studer L, Tabar V, McKay RD, (1998) Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats. Nat Neurosci 1: 290-295.
    • (1998) Nat Neurosci , vol.1 , pp. 290-295
    • Studer, L.1    Tabar, V.2    McKay, R.D.3
  • 14
    • 10444252732 scopus 로고    scopus 로고
    • Transplantation of human embryonic stem cell-derived neural progenitors improves behavioral deficit in Parkinsonian rats
    • Ben-Hur T, Idelson M, Khaner H, Pera M, Reinhartz E, et al. (2004) Transplantation of human embryonic stem cell-derived neural progenitors improves behavioral deficit in Parkinsonian rats. Stem Cells 22: 1246-1255.
    • (2004) Stem Cells , vol.22 , pp. 1246-1255
    • Ben-Hur, T.1    Idelson, M.2    Khaner, H.3    Pera, M.4    Reinhartz, E.5
  • 15
    • 0141673859 scopus 로고    scopus 로고
    • Functional characterization of dopaminergic neurons derived from rodent mesencephalic progenitor cells
    • Storch A, Lester HA, Boehm BO, Schwarz J, (2003) Functional characterization of dopaminergic neurons derived from rodent mesencephalic progenitor cells. J Chem Neuroanat 26: 133-142.
    • (2003) J Chem Neuroanat , vol.26 , pp. 133-142
    • Storch, A.1    Lester, H.A.2    Boehm, B.O.3    Schwarz, J.4
  • 16
    • 0034065380 scopus 로고    scopus 로고
    • Improving the survival of grafted dopaminergic neurons: a review over current approaches
    • Brundin P, Karlsson J, Emgard M, Schierle GS, Hansson O, et al. (2000) Improving the survival of grafted dopaminergic neurons: a review over current approaches. Cell Transplant 9: 179-195.
    • (2000) Cell Transplant , vol.9 , pp. 179-195
    • Brundin, P.1    Karlsson, J.2    Emgard, M.3    Schierle, G.S.4    Hansson, O.5
  • 17
    • 38149097773 scopus 로고    scopus 로고
    • How to improve the survival of the fetal ventral mesencephalic cell transplanted in Parkinson's disease?
    • Liu J, Huang HY, (2007) How to improve the survival of the fetal ventral mesencephalic cell transplanted in Parkinson's disease? Neurosci Bull 23: 377-382.
    • (2007) Neurosci Bull , vol.23 , pp. 377-382
    • Liu, J.1    Huang, H.Y.2
  • 18
    • 39749112525 scopus 로고    scopus 로고
    • Survival and functional recovery of transplanted human dopaminergic neurons into hemiparkinsonian rats depend on the cannula size of the implantation instrument
    • Steiner B, Winter C, Blumensath S, Paul G, Harnack D, et al. (2008) Survival and functional recovery of transplanted human dopaminergic neurons into hemiparkinsonian rats depend on the cannula size of the implantation instrument. J Neurosci Methods 169: 128-134.
    • (2008) J Neurosci Methods , vol.169 , pp. 128-134
    • Steiner, B.1    Winter, C.2    Blumensath, S.3    Paul, G.4    Harnack, D.5
  • 19
    • 0031455188 scopus 로고    scopus 로고
    • Survival of nigral grafts within the striatum of marmosets with 6-OHDA lesions depends critically on donor embryo age
    • Annett LE, Torres EM, Clarke DJ, Ishida Y, Barker RA, et al. (1997) Survival of nigral grafts within the striatum of marmosets with 6-OHDA lesions depends critically on donor embryo age. Cell Transplant 6: 557-569.
    • (1997) Cell Transplant , vol.6 , pp. 557-569
    • Annett, L.E.1    Torres, E.M.2    Clarke, D.J.3    Ishida, Y.4    Barker, R.A.5
  • 20
    • 19944376116 scopus 로고    scopus 로고
    • Electrical and neurotransmitter activity of mature neurons derived from mouse embryonic stem cells by Sox-1 lineage selection and directed differentiation
    • Lang RJ, Haynes JM, Kelly J, Johnson J, Greenhalgh J, et al. (2004) Electrical and neurotransmitter activity of mature neurons derived from mouse embryonic stem cells by Sox-1 lineage selection and directed differentiation. Eur J Neurosci 20: 3209-3221.
    • (2004) Eur J Neurosci , vol.20 , pp. 3209-3221
    • Lang, R.J.1    Haynes, J.M.2    Kelly, J.3    Johnson, J.4    Greenhalgh, J.5
  • 21
    • 79957597415 scopus 로고    scopus 로고
    • Midbrain and forebrain patterning delivers immunocytochemically and functionally similar populations of neuropeptide Y containing GABAergic neurons
    • Khaira SK, Nefzger CM, Beh SJ, Pouton CW, Haynes JM, (2011) Midbrain and forebrain patterning delivers immunocytochemically and functionally similar populations of neuropeptide Y containing GABAergic neurons. Neurochem Int 59: 413-420.
    • (2011) Neurochem Int , vol.59 , pp. 413-420
    • Khaira, S.K.1    Nefzger, C.M.2    Beh, S.J.3    Pouton, C.W.4    Haynes, J.M.5
  • 22
    • 34147199795 scopus 로고    scopus 로고
    • Heterogeneous population of dopaminergic neurons derived from mouse embryonic stem cells: preliminary phenotyping based on receptor expression and function
    • Raye WS, Tochon-Danguy N, Pouton CW, Haynes JM, (2007) Heterogeneous population of dopaminergic neurons derived from mouse embryonic stem cells: preliminary phenotyping based on receptor expression and function. European Journal of Neuroscience 25: 1961-1970.
    • (2007) European Journal of Neuroscience , vol.25 , pp. 1961-1970
    • Raye, W.S.1    Tochon-Danguy, N.2    Pouton, C.W.3    Haynes, J.M.4
  • 23
    • 71649099124 scopus 로고    scopus 로고
    • P2X2, P2X4 and P2Y1 receptors elevate intracellular Ca2+ in mouse embryonic stem cell-derived GABAergic neurons
    • Khaira SK, Pouton CW, Haynes JM, (2009) P2X2, P2X4 and P2Y1 receptors elevate intracellular Ca2+ in mouse embryonic stem cell-derived GABAergic neurons. Br J Pharmacol 158: 1922-1931.
    • (2009) Br J Pharmacol , vol.158 , pp. 1922-1931
    • Khaira, S.K.1    Pouton, C.W.2    Haynes, J.M.3
  • 24
    • 35748954370 scopus 로고    scopus 로고
    • GABA: a pioneer transmitter that excites immature neurons and generates primitive oscillations
    • Ben-Ari Y, Gaiarsa JL, Tyzio R, Khazipov R, (2007) GABA: a pioneer transmitter that excites immature neurons and generates primitive oscillations. Physiol Rev 87: 1215-1284.
    • (2007) Physiol Rev , vol.87 , pp. 1215-1284
    • Ben-Ari, Y.1    Gaiarsa, J.L.2    Tyzio, R.3    Khazipov, R.4
  • 25
    • 77956319634 scopus 로고    scopus 로고
    • Calcium-dependent mitochondrial function and dysfunction in neurons
    • Pivovarova NB, Andrews SB, (2010) Calcium-dependent mitochondrial function and dysfunction in neurons. FEBS J 277: 3622-3636.
    • (2010) FEBS J , vol.277 , pp. 3622-3636
    • Pivovarova, N.B.1    Andrews, S.B.2
  • 26
    • 0037272948 scopus 로고    scopus 로고
    • alpha(1)-Adrenoceptor effects mediated by protein kinase C alpha in human cultured prostatic stromal cells
    • Preston A, Haynes JM, (2003) alpha(1)-Adrenoceptor effects mediated by protein kinase C alpha in human cultured prostatic stromal cells. Br J Pharmacol 138: 218-224.
    • (2003) Br J Pharmacol , vol.138 , pp. 218-224
    • Preston, A.1    Haynes, J.M.2
  • 27
    • 0021895138 scopus 로고
    • A NEW GENERATION OF CA-2+ INDICATORS WITH GREATLY IMPROVED FLUORESCENCE PROPERTIES
    • Grynkiewicz G, Poenie M, Tsien RY, (1985) A NEW GENERATION OF CA-2+ INDICATORS WITH GREATLY IMPROVED FLUORESCENCE PROPERTIES. Journal of Biological Chemistry 260: 3440-3450.
    • (1985) Journal of Biological Chemistry , vol.260 , pp. 3440-3450
    • Grynkiewicz, G.1    Poenie, M.2    Tsien, R.Y.3
  • 28
    • 0025805515 scopus 로고
    • Determination of Fura-2 dissociation constants following adjustment of the apparent Ca-EGTA association constant for temperature and ionic strength
    • Groden DL, Guan Z, Stokes BT, (1991) Determination of Fura-2 dissociation constants following adjustment of the apparent Ca-EGTA association constant for temperature and ionic strength. Cell Calcium 12: 279-287.
    • (1991) Cell Calcium , vol.12 , pp. 279-287
    • Groden, D.L.1    Guan, Z.2    Stokes, B.T.3
  • 29
    • 0032825227 scopus 로고    scopus 로고
    • Fluorescence imaging of changes in intracellular chloride in living brain slices
    • Inglefield JR, Schwartz-Bloom RD, (1999) Fluorescence imaging of changes in intracellular chloride in living brain slices. Methods 18: 197-203.
    • (1999) Methods , vol.18 , pp. 197-203
    • Inglefield, J.R.1    Schwartz-Bloom, R.D.2
  • 30
    • 0023918379 scopus 로고
    • Estimation of Intracellular Chloride Activity in Isolated Perfused Rabbit Proximal Convoluted Tubules Using a Fluorescent Indicator
    • Krapf R, Berry CA, Verkman AS, (1988) Estimation of Intracellular Chloride Activity in Isolated Perfused Rabbit Proximal Convoluted Tubules Using a Fluorescent Indicator. Biophysical Journal 53: 955-962.
    • (1988) Biophysical Journal , vol.53 , pp. 955-962
    • Krapf, R.1    Berry, C.A.2    Verkman, A.S.3
  • 31
    • 12144286982 scopus 로고    scopus 로고
    • Generation of embryonic stem cells and transgenic mice expressing green fluorescence protein in midbrain dopaminergic neurons
    • Zhao SL, Maxwell S, Jimenez-Beristain A, Vives J, Kuehner E, et al. (2004) Generation of embryonic stem cells and transgenic mice expressing green fluorescence protein in midbrain dopaminergic neurons. European Journal of Neuroscience 19: 1133-1140.
    • (2004) European Journal of Neuroscience , vol.19 , pp. 1133-1140
    • Zhao, S.L.1    Maxwell, S.2    Jimenez-Beristain, A.3    Vives, J.4    Kuehner, E.5
  • 32
    • 0027243522 scopus 로고
    • Two functionally different glutamate receptors of the kainate subtype in embryonic rat mesencephalic cells
    • di Porzio U, Smith SV, Novotny EA, Morelli F, Barker JL, (1993) Two functionally different glutamate receptors of the kainate subtype in embryonic rat mesencephalic cells. Exp Neurol 120: 202-213.
    • (1993) Exp Neurol , vol.120 , pp. 202-213
    • di Porzio, U.1    Smith, S.V.2    Novotny, E.A.3    Morelli, F.4    Barker, J.L.5
  • 33
    • 27144549251 scopus 로고    scopus 로고
    • Differential maturation of GABA action and anion reversal potential in spinal lamina I neurons: impact of chloride extrusion capacity
    • Cordero-Erausquin M, Coull JA, Boudreau D, Rolland M, De Koninck Y, (2005) Differential maturation of GABA action and anion reversal potential in spinal lamina I neurons: impact of chloride extrusion capacity. J Neurosci 25: 9613-9623.
    • (2005) J Neurosci , vol.25 , pp. 9613-9623
    • Cordero-Erausquin, M.1    Coull, J.A.2    Boudreau, D.3    Rolland, M.4    De Koninck, Y.5
  • 34
    • 0033590541 scopus 로고    scopus 로고
    • The K+/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation
    • Rivera C, Voipio J, Payne JA, Ruusuvuori E, Lahtinen H, et al. (1999) The K+/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation. Nature 397: 251-255.
    • (1999) Nature , vol.397 , pp. 251-255
    • Rivera, C.1    Voipio, J.2    Payne, J.A.3    Ruusuvuori, E.4    Lahtinen, H.5
  • 35
    • 58649107121 scopus 로고    scopus 로고
    • A potential reservoir of immature dopaminergic replacement neurons in the adult mammalian olfactory bulb
    • Pignatelli A, Ackman JB, Vigetti D, Beltrami AP, Zucchini S, et al. (2009) A potential reservoir of immature dopaminergic replacement neurons in the adult mammalian olfactory bulb. Pflugers Arch 457: 899-915.
    • (2009) Pflugers Arch , vol.457 , pp. 899-915
    • Pignatelli, A.1    Ackman, J.B.2    Vigetti, D.3    Beltrami, A.P.4    Zucchini, S.5
  • 36
    • 0029794366 scopus 로고    scopus 로고
    • Excitatory GABA responses in embryonic and neonatal cortical slices demonstrated by gramicidin perforated-patch recordings and calcium imaging
    • Owens DF, Boyce LH, Davis MB, Kriegstein AR, (1996) Excitatory GABA responses in embryonic and neonatal cortical slices demonstrated by gramicidin perforated-patch recordings and calcium imaging. J Neurosci 16: 6414-6423.
    • (1996) J Neurosci , vol.16 , pp. 6414-6423
    • Owens, D.F.1    Boyce, L.H.2    Davis, M.B.3    Kriegstein, A.R.4
  • 37
    • 0348042110 scopus 로고    scopus 로고
    • Expression of the KCl cotransporter KCC2 parallels neuronal maturation and the emergence of low intracellular chloride
    • Stein V, Hermans-Borgmeyer I, Jentsch TJ, Hubner CA, (2004) Expression of the KCl cotransporter KCC2 parallels neuronal maturation and the emergence of low intracellular chloride. J Comp Neurol 468: 57-64.
    • (2004) J Comp Neurol , vol.468 , pp. 57-64
    • Stein, V.1    Hermans-Borgmeyer, I.2    Jentsch, T.J.3    Hubner, C.A.4
  • 38
    • 16244388582 scopus 로고    scopus 로고
    • Distinct properties of functional KCC2 expression in immature mouse hippocampal neurons in culture and in acute slices
    • Khirug S, Huttu K, Ludwig A, Smirnov S, Voipio J, et al. (2005) Distinct properties of functional KCC2 expression in immature mouse hippocampal neurons in culture and in acute slices. European Journal of Neuroscience 21: 899-904.
    • (2005) European Journal of Neuroscience , vol.21 , pp. 899-904
    • Khirug, S.1    Huttu, K.2    Ludwig, A.3    Smirnov, S.4    Voipio, J.5
  • 39
    • 21744457299 scopus 로고    scopus 로고
    • Contribution of L-type channels to Ca2+ regulation of neuronal properties in early developing purkinje neurons
    • Gruol DL, Netzeband JG, Quina LA, Blakely-Gonzalez PK, (2005) Contribution of L-type channels to Ca2+ regulation of neuronal properties in early developing purkinje neurons. Cerebellum 4: 128-139.
    • (2005) Cerebellum , vol.4 , pp. 128-139
    • Gruol, D.L.1    Netzeband, J.G.2    Quina, L.A.3    Blakely-Gonzalez, P.K.4
  • 40
    • 23944499078 scopus 로고    scopus 로고
    • BDNF acutely modulates synaptic transmission and calcium signalling in developing cortical neurons
    • He J, Gong H, Luo Q, (2005) BDNF acutely modulates synaptic transmission and calcium signalling in developing cortical neurons. Cell Physiol Biochem 16: 69-76.
    • (2005) Cell Physiol Biochem , vol.16 , pp. 69-76
    • He, J.1    Gong, H.2    Luo, Q.3
  • 41
    • 31544461787 scopus 로고    scopus 로고
    • Intracellular Ca2+ regulation in rat motoneurons during development
    • Dayanithi G, Mechaly I, Viero C, Aptel H, Alphandery S, et al. (2006) Intracellular Ca2+ regulation in rat motoneurons during development. Cell Calcium 39: 237-246.
    • (2006) Cell Calcium , vol.39 , pp. 237-246
    • Dayanithi, G.1    Mechaly, I.2    Viero, C.3    Aptel, H.4    Alphandery, S.5
  • 42
    • 35348865752 scopus 로고    scopus 로고
    • Bursting in substantia nigra pars reticulata neurons in vitro: possible relevance for Parkinson disease
    • Ibanez-Sandoval O, Carrillo-Reid L, Galarraga E, Tapia D, Mendoza E, et al. (2007) Bursting in substantia nigra pars reticulata neurons in vitro: possible relevance for Parkinson disease. J Neurophysiol 98: 2311-2323.
    • (2007) J Neurophysiol , vol.98 , pp. 2311-2323
    • Ibanez-Sandoval, O.1    Carrillo-Reid, L.2    Galarraga, E.3    Tapia, D.4    Mendoza, E.5
  • 44
    • 79955548476 scopus 로고    scopus 로고
    • Properties of dopaminergic neurons in organotypic mesencephalic-striatal co-cultures - evidence for a facilitatory effect of dopamine on the glutamatergic input mediated by alpha-1 adrenergic receptors
    • Cucchiaroni ML, Freestone PS, Berretta N, Viscomi MT, Bisicchia E, et al. (2011) Properties of dopaminergic neurons in organotypic mesencephalic-striatal co-cultures- evidence for a facilitatory effect of dopamine on the glutamatergic input mediated by alpha-1 adrenergic receptors. Eur J Neurosci.
    • (2011) Eur J Neurosci
    • Cucchiaroni, M.L.1    Freestone, P.S.2    Berretta, N.3    Viscomi, M.T.4    Bisicchia, E.5
  • 45
    • 79956285222 scopus 로고    scopus 로고
    • High-frequency, short-latency disinhibition bursting of midbrain dopaminergic neurons
    • Lobb CJ, Wilson CJ, Paladini CA, (2011) High-frequency, short-latency disinhibition bursting of midbrain dopaminergic neurons. J Neurophysiol 105: 2501-2511.
    • (2011) J Neurophysiol , vol.105 , pp. 2501-2511
    • Lobb, C.J.1    Wilson, C.J.2    Paladini, C.A.3
  • 46
    • 77956449629 scopus 로고    scopus 로고
    • Ca2+ and cAMP signaling in human embryonic stem cell-derived dopamine neurons
    • Malmersjo S, Liste I, Dyachok O, Tengholm A, Arenas E, et al. (2010) Ca2+ and cAMP signaling in human embryonic stem cell-derived dopamine neurons. Stem Cells Dev 19: 1355-1364.
    • (2010) Stem Cells Dev , vol.19 , pp. 1355-1364
    • Malmersjo, S.1    Liste, I.2    Dyachok, O.3    Tengholm, A.4    Arenas, E.5
  • 47
    • 77951297410 scopus 로고    scopus 로고
    • Developmental regulation and neuroprotective effects of striatal tonic GABAA currents
    • Santhakumar V, Jones RT, Mody I, (2010) Developmental regulation and neuroprotective effects of striatal tonic GABAA currents. Neuroscience 167: 644-655.
    • (2010) Neuroscience , vol.167 , pp. 644-655
    • Santhakumar, V.1    Jones, R.T.2    Mody, I.3
  • 48
    • 0035695808 scopus 로고    scopus 로고
    • GABA and L-glutamic acid release in en bloc resection slices of human hippocampus: an in vitro microdialysis study
    • Goren MZ, Onat F, Ozkara C, Ozyurt E, Eskazan E, et al. (2001) GABA and L-glutamic acid release in en bloc resection slices of human hippocampus: an in vitro microdialysis study. Neurol Sci 22: 297-302.
    • (2001) Neurol Sci , vol.22 , pp. 297-302
    • Goren, M.Z.1    Onat, F.2    Ozkara, C.3    Ozyurt, E.4    Eskazan, E.5
  • 49
    • 0037716761 scopus 로고    scopus 로고
    • A new model for prenatal brain damage. I. GABAA receptor activation induces cell death in developing rat hippocampus
    • Nunez JL, Alt JJ, McCarthy MM, (2003) A new model for prenatal brain damage. I. GABAA receptor activation induces cell death in developing rat hippocampus. Exp Neurol 181: 258-269.
    • (2003) Exp Neurol , vol.181 , pp. 258-269
    • Nunez, J.L.1    Alt, J.J.2    McCarthy, M.M.3
  • 50
    • 0042536473 scopus 로고    scopus 로고
    • Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity
    • Arundine M, Tymianski M, (2003) Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity. Cell Calcium 34: 325-337.
    • (2003) Cell Calcium , vol.34 , pp. 325-337
    • Arundine, M.1    Tymianski, M.2
  • 51
    • 68749114987 scopus 로고    scopus 로고
    • Impaired glutamate homeostasis and programmed cell death in a chronic MPTP mouse model of Parkinson's disease
    • Meredith GE, Totterdell S, Beales M, Meshul CK, (2009) Impaired glutamate homeostasis and programmed cell death in a chronic MPTP mouse model of Parkinson's disease. Exp Neurol 219: 334-340.
    • (2009) Exp Neurol , vol.219 , pp. 334-340
    • Meredith, G.E.1    Totterdell, S.2    Beales, M.3    Meshul, C.K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.