Nonlinear model predictive control of fed-batch cultures of micro-organisms exhibiting overflow metabolism: Assessment and robustness

Computers and Chemical Engineering

Volumn 39, Issue , 2012, Pages 143-151

  Santos, L O ^a   Dewasme, L ^c   Coutinho, D ^b   Wouwer, A Vande ^c  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^c UNIVERSITY OF MONS   (Belgium)

Author keywords

Biotechnology; Fermentation; Min max optimization; Overflow metabolism; Predictive control

Indexed keywords

BIOPROCESSES; E. COLI; FED-BATCH CULTURES; FEED FLOW RATE; GLUCOSE FERMENTATION; GLUCOSE OXIDATION; METABOLIC PATHWAYS; MIN-MAX OPTIMIZATION; MONTE CARLO ANALYSIS; NON-LINEAR MODEL; NONLINEAR MODEL PREDICTIVE CONTROL; OBJECTIVE FUNCTIONS; OVERFLOW METABOLISM; PREDICTIVE CONTROL; ROBUST FORMULATIONS;

BATCH CELL CULTURE; BIOTECHNOLOGY; ESCHERICHIA COLI; ETHANOL; FERMENTATION; GLUCOSE; NONLINEAR SYSTEMS; OPTIMIZATION; PHYSIOLOGY; PREDICTIVE CONTROL SYSTEMS; VOLATILE FATTY ACIDS;

METABOLISM;

EID: 84857443726     PISSN: 00981354     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.compchemeng.2011.12.010     Document Type: Article

References (23)

1. Abbo A.J., Sloan S.W. A smooth hyperbolic approximation to the Mohr-Coulomb yield criterion. Computers & Structures 1995, 54(3):427-441.
2. Akesson, M. (1999). Probing control of glucose feeding in Escherichia coli cultivations. Ph.D. thesis, Lund Institute of Technology.
3. Axelsson J.P. On the role of adaptive controllers in fed-batch yeast production. Adaptive control of chemical processes 1988, (ADCHEM 88) 1988.
4. Axelsson, J. P. (1989). Modelling and control of fermentation processes. Ph.D. thesis, Department of Automatic Control, Lund Institute of Technology, Sweden.
5. Balakrishna S., Biegler L.T. Targeting strategies for the synthesis and energy integration of nonisothermal reactor networks. Industrial Engineering Chemistry Research 1992, 31(9):2152-2164.
6. Cannon M. Efficient nonlinear model predictive control algorithms. Annual Reviews in Control 2004, 28(2):229-237.
7. Chen L., Bastin G., van Breusegem V. A case study of adaptive nonlinear regulation of fed-batch biological reactors. Automatica 1995, 31(1):55-65.
8. Crabtree H. Observations on the carbohydrate metabolism of tumors. Biochemical Journal 1929, 23(3):536-545.
9. Dewasme L., Richelle A., Dehottay P., Georges P., Remy M., Bogaerts P., et al. Linear robust control of S. cerevisiae fed-batch cultures at different scales. Biochemical Engineering Journal 2010, 53(1):26-37.
10. Dewasme L., Srinivasan B., Perrier M., Vande Wouwer A. Extremum-seeking algorithm design for fed-batch cultures of microorganisms with overflow metabolism. Journal of Process Control 2011, 21(7):1092-1104.
11. Hafidi, G. (2008). Application de la commande prédictive non-linéaire à la commande de culture de bactéries Escherichia coli. Ph.D. thesis, Supélec, France.
12. Johnson, S. G. (2008). The NLopt nonlinear-optimization package. http://ab-initio.mit.edu/nlopt.
13. Kayihan A., Doyle F.J. Friction compensation for a process control valve. Control Engineering Practice 2000, 8(7):799-812.
14. Nonlinear model predictive control - Towards new challenging applications, vol. 384 of Lecture Notes in Control and Information Sciences 2009, Springer. L. Magni, D.M. Raimondo, F. Allgöwer (Eds.).
15. Nagy Z., Braatz R.D. Robust nonlinear model predictive control of batch processes. AIChE Journal 2003, 249(7):1776-1786.
16. Nagy Z.K., Braatz R.D. Open-loop and closed-loop robust optimal control of batch processes using distributional and worst-case analysis. Journal of Process Control 2004, 14(4):411-422.
17. Pomerleau, Y. (1990). Modélisation et commande d'un procédé fed-batch de culture des levures pain. Ph.D. thesis, Département de génie chimique. Ecole Polytechnique de Montréal.
18. Qin S.J., Badgwell T.A. A survey of industrial model predictive control technology. Control Engineering Practice 2003, 11:733-764.
19. Rocha, I. (2003). Model-based strategies for computer-aided operation of a recombinant E. coli fermentation. Ph.D. thesis, University of Minho, Portugal.
20. Santos L.O., Dewasme L., Hantson A.-L., Vande Wouwer A. Nonlinear model predictive control of fed-batch cultures of micro-organisms exhibiting overflow metabolism. IEEE multi-conference on systems and control (MSC) 2010, 1608-1613.
21. Sloan S.W., Booker J.R. Removal of singularities in Tresca and Mohr-Coulomb yield functions. Communications in Applied Numerical Methods 1986, 2(2):173-179.
22. Sonnleitner B., Käppeli O. Growth of Saccharomyces cerevisiae is controlled by its limited respiratory capacity: Formulation and verification of a hypothesis. Biotechnology & Bioengineering 1986, 28(6):927-937.
23. Valentinotti S., Srinivasan B., Holmberg U., Bonvin D., Cannizzaro C., Rhiel M., et al. Optimal operation of fed-batch fermentations via adaptive control of overflow metabolite. Control Engineering Practice 2003, 11(6):665-674.