Identification of differentially expressed genes in matched formalin-fixed paraffin-embedded primary and metastatic melanoma tumor pairs

Pigment Cell and Melanoma Research

Volumn 25, Issue 2, 2012, Pages 284-286

  Jewell, Rosalyn ^a   Mitra, Angana ^a   Conway, Caroline ^a   Iremonger, James ^b   Walker, Christy ^a   de Kort, Floor ^c   Cook, Martin ^d   Boon, Andy ^e   Speirs, Valerie ^b   Newton Bishop, Julia ^a  

^a ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

^b Section of Pathology and Tumour Biology   (United Kingdom)

^c BV Leiden   (Netherlands)

^d ROYAL SURREY COUNTY HOSPITAL   (United Kingdom)

^e LEEDS TEACHING HOSPITALS NHS TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER GROWTH; EPIGENETICS; GENE EXPRESSION; GENE IDENTIFICATION; GENETIC VARIABILITY; LETTER; LYMPH NODE METASTASIS; MELANOMA; REAL TIME POLYMERASE CHAIN REACTION; SENTINEL LYMPH NODE BIOPSY; SPECTROPHOTOMETRY;

ADULT; FORMALDEHYDE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, NEOPLASM; HUMANS; MELANOMA; NEOPLASM METASTASIS; PARAFFIN EMBEDDING; RNA, NEOPLASM; SKIN NEOPLASMS; TISSUE FIXATION;

EID: 84857443003     PISSN: 17551471     EISSN: 1755148X     Source Type: Journal    
DOI: 10.1111/j.1755-148X.2011.00965.x     Document Type: Letter

References (9)

1. Augustine, C.K., Jung, S.H., Sohn, I., Yoo, J.S., Yoshimoto, Y., Olson, J.A. Jr, Friedman, H.S., Ali-Osman, F., and Tyler, D.S. (2010). Gene expression signatures as a guide to treatment strategies for in-transit metastatic melanoma. Mol. Cancer Ther. 9, 779-790.
2. Conway, C., Mitra, A., Jewell, R. et al. (2009). Gene expression profiling of paraffin-embedded primary melanoma using the DASL assay identifies increased osteopontin expression as predictive of reduced relapse-free survival. Clin. Cancer Res. 15, 6939-6946.
3. Cookson, W., Liang, L., Abecasis, G., Moffatt, M., and Lathrop, M. (2009). Mapping complex disease traits with global gene expression. Nat. Rev. Genet. 10, 184-194.
4. Fidler, I.J., and Kripke, M.L. (1977). Metastasis results from preexisting variant cells within a malignant tumor. Science 197, 893-895.
5. Harbst, K., Staaf, J., Masback, A., Olsson, H., Ingvar, C., Vallon-Christersson, J., Ringner, M., Borg, A., and Jonsson, G. (2010). Multiple metastases from cutaneous malignant melanoma patients may display heterogeneous genomic and epigenomic patterns. Melanoma Res. 20, 381-391.
6. Ravo, M., Mutarelli, M., Ferraro, L. et al. (2008). Quantitative expression profiling of highly degraded RNA from formalin-fixed, paraffin-embedded breast tumor biopsies by oligonucleotide microarrays. Lab. Invest. 88, 430-440.
7. Riker, A.I., Enkemann, S.A., Fodstad, O. et al. (2008). The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis. BMC Med. Genomics 1, 13.
8. Turner, N., and Grose, R. (2010). Fibroblast growth factor signalling: from development to cancer. Nat. Rev. Cancer 10, 116-129.
9. Winnepenninckx, V., Lazar, V., Michiels, S. et al. (2006). Gene expression profiling of primary cutaneous melanoma and clinical outcome. J. Natl Cancer Inst. 98, 472-482.