Imatinib resistance and blast transformation of chronic myeloid leukemia associated with a novel tri-nucleotide insertion mutation of BCR-ABL kinase domain at position K294.

Annals of hematology

Volumn 91, Issue 1, 2012, Pages 125-127

  Nadarajan, Veera Sekaran ^a,b   Ang, Chow Hiang ^a   Syed Sultan, Mohamed Kamil ^b   Bee, Ping Chong ^a  

^a UNIVERSITY OF MALAYA   (Malaysia)

^b UNIVERSITY MALAYA MEDICAL CENTRE   (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; IMATINIB; PIPERAZINE DERIVATIVE; PROTEIN KINASE INHIBITOR; PYRIMIDINE DERIVATIVE;

ADOLESCENT; CASE REPORT; CHRONIC MYELOID LEUKEMIA; DRUG RESISTANCE; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; LETTER; LYMPHOCYTE ACTIVATION; MALE; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY;

ADOLESCENT; DNA MUTATIONAL ANALYSIS; DRUG RESISTANCE, NEOPLASM; FUSION PROTEINS, BCR-ABL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; LYMPHOCYTE ACTIVATION; MALE; MUTAGENESIS, INSERTIONAL; PIPERAZINES; PROTEIN KINASE INHIBITORS; PYRIMIDINES;

EID: 84857420709     PISSN: None     EISSN: 14320584     Source Type: Journal    
DOI: 10.1007/s00277-011-1215-2     Document Type: Letter

References (0)