메뉴 건너뛰기




Volumn 99, Issue , 2012, Pages 1-30

Let's Make It Happen. The Role of let-7 MicroRNA in Development

Author keywords

Argonaute; C. elegans; Cancer; Development; Let 7; Lin 4; Lin 41; MicroRNA

Indexed keywords


EID: 84857416455     PISSN: 00702153     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-387038-4.00001-X     Document Type: Chapter
Times cited : (52)

References (161)
  • 1
    • 24144494563 scopus 로고    scopus 로고
    • The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans
    • Abbott A.L., Alvarez-Saavedra E., Miska E.A., Lau N.C., Bartel D.P., Horvitz H.R., Ambros V. The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans. Dev. Cell 2005, 9:403-414.
    • (2005) Dev. Cell , vol.9 , pp. 403-414
    • Abbott, A.L.1    Alvarez-Saavedra, E.2    Miska, E.A.3    Lau, N.C.4    Bartel, D.P.5    Horvitz, H.R.6    Ambros, V.7
  • 2
    • 0038708326 scopus 로고    scopus 로고
    • The Caenorhabditis elegans hunchback-like Gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs
    • Abrahante J.E., Daul A.L., Li M., Volk M.L., Tennessen J.M., Miller E.A., Rougvie A.E. The Caenorhabditis elegans hunchback-like Gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs. Dev. Cell 2003, 4:625-637.
    • (2003) Dev. Cell , vol.4 , pp. 625-637
    • Abrahante, J.E.1    Daul, A.L.2    Li, M.3    Volk, M.L.4    Tennessen, J.M.5    Miller, E.A.6    Rougvie, A.E.7
  • 3
    • 33847245910 scopus 로고    scopus 로고
    • Comparison of siRNA-induced off-target RNA and protein effects
    • Alemán L.M., Doench J., Sharp P.A. Comparison of siRNA-induced off-target RNA and protein effects. RNA 2007, 13:385-395.
    • (2007) RNA , vol.13 , pp. 385-395
    • Alemán, L.M.1    Doench, J.2    Sharp, P.A.3
  • 4
    • 0024963695 scopus 로고
    • A hierarchy of regulatory genes controls a larva-to-adult developmental switch in C. elegans
    • Ambros V. A hierarchy of regulatory genes controls a larva-to-adult developmental switch in C. elegans. Cell 1989, 57:49-57.
    • (1989) Cell , vol.57 , pp. 49-57
    • Ambros, V.1
  • 5
    • 0021771445 scopus 로고
    • Heterochronic mutants of the nematode Caenorhabditis elegans
    • Ambros V., Horvitz H.R. Heterochronic mutants of the nematode Caenorhabditis elegans. Science 1984, 226:409-416.
    • (1984) Science , vol.226 , pp. 409-416
    • Ambros, V.1    Horvitz, H.R.2
  • 7
    • 0025989344 scopus 로고
    • Temporal regulation of lin-14 by the antagonistic action of two other heterochronic genes, lin-4 and lin-28
    • Arasu P., Wightman B., Ruvkun G. Temporal regulation of lin-14 by the antagonistic action of two other heterochronic genes, lin-4 and lin-28. Genes Dev. 1991, 5:1825-1833.
    • (1991) Genes Dev. , vol.5 , pp. 1825-1833
    • Arasu, P.1    Wightman, B.2    Ruvkun, G.3
  • 11
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel D.P. MicroRNAs: Target recognition and regulatory functions. Cell 2009, 136:215-233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 12
    • 37649021046 scopus 로고    scopus 로고
    • Identification of human microRNA targets from isolated argonaute protein complexes
    • Beitzinger M., Peters L., Zhu J.Y., Kremmer E., Meister G. Identification of human microRNA targets from isolated argonaute protein complexes. RNA Biol. 2007, 4:76-84.
    • (2007) RNA Biol. , vol.4 , pp. 76-84
    • Beitzinger, M.1    Peters, L.2    Zhu, J.Y.3    Kremmer, E.4    Meister, G.5
  • 15
    • 64249129511 scopus 로고    scopus 로고
    • Nuclear hormone receptor regulation of microRNAs controls developmental progression
    • Bethke A., Fielenbach N., Wang Z., Mangelsdorf D.J., Antebi A. Nuclear hormone receptor regulation of microRNAs controls developmental progression. Science 2009, 324:95-98.
    • (2009) Science , vol.324 , pp. 95-98
    • Bethke, A.1    Fielenbach, N.2    Wang, Z.3    Mangelsdorf, D.J.4    Antebi, A.5
  • 16
    • 28844459719 scopus 로고    scopus 로고
    • Trans-splicing and operons
    • The C. elegans Research Community, WormBook, L.R. Girard (Ed.)
    • Blumenthal T. Trans-splicing and operons. WormBook 2005, The C. elegans Research Community, WormBook. L.R. Girard (Ed.).
    • (2005) WormBook
    • Blumenthal, T.1
  • 17
    • 1642499415 scopus 로고    scopus 로고
    • Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs
    • Bohnsack M.T., Czaplinski K., Gorlich D. Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs. RNA 2004, 10:185-191.
    • (2004) RNA , vol.10 , pp. 185-191
    • Bohnsack, M.T.1    Czaplinski, K.2    Gorlich, D.3
  • 20
    • 4644227434 scopus 로고    scopus 로고
    • Trans-splicing and polyadenylation of let-7 microRNA primary transcripts
    • Bracht J., Hunter S., Eachus R., Weeks P., Pasquinelli A.E. Trans-splicing and polyadenylation of let-7 microRNA primary transcripts. RNA 2004, 10:1586-1594.
    • (2004) RNA , vol.10 , pp. 1586-1594
    • Bracht, J.1    Hunter, S.2    Eachus, R.3    Weeks, P.4    Pasquinelli, A.E.5
  • 21
    • 78349307166 scopus 로고    scopus 로고
    • Regulation of lin-4 miRNA expression, organismal growth and development by a conserved RNA binding protein in C. elegans
    • Bracht J.R., Van Wynsberghe P.M., Mondol V., Pasquinelli A.E. Regulation of lin-4 miRNA expression, organismal growth and development by a conserved RNA binding protein in C. elegans. Dev. Biol. 2010, 348:210-221.
    • (2010) Dev. Biol. , vol.348 , pp. 210-221
    • Bracht, J.R.1    Van Wynsberghe, P.M.2    Mondol, V.3    Pasquinelli, A.E.4
  • 23
    • 77953123717 scopus 로고    scopus 로고
    • The nuclear export receptor XPO-1 supports primary miRNA processing in C. elegans and Drosophila
    • Bussing I., Yang J.-S., Lai E.C., Grosshans H. The nuclear export receptor XPO-1 supports primary miRNA processing in C. elegans and Drosophila. EMBO J. 2010, 29:1830-1839.
    • (2010) EMBO J. , vol.29 , pp. 1830-1839
    • Bussing, I.1    Yang, J.-S.2    Lai, E.C.3    Grosshans, H.4
  • 24
    • 50549095181 scopus 로고    scopus 로고
    • Let-7 microRNAs in development, stem cells and cancer
    • Büssing I., Slack F.J., Großhans H. let-7 microRNAs in development, stem cells and cancer. Trends Mol. Med. 2008, 14:400-409.
    • (2008) Trends Mol. Med. , vol.14 , pp. 400-409
    • Büssing, I.1    Slack, F.J.2    Großhans, H.3
  • 25
    • 45849084987 scopus 로고    scopus 로고
    • Temporal regulation of metamorphic processes in Drosophila by the let-7 and miR-125 heterochronic microRNAs
    • Caygill E.E., Johnston L.A. Temporal regulation of metamorphic processes in Drosophila by the let-7 and miR-125 heterochronic microRNAs. Curr. Biol. 2008, 18:943-950.
    • (2008) Curr. Biol. , vol.18 , pp. 943-950
    • Caygill, E.E.1    Johnston, L.A.2
  • 26
    • 0019509303 scopus 로고
    • Mutations that lead to reiterations in the cell lineages of C. elegans
    • Chalfie M., Horvitz H.R., Sulston J.E. Mutations that lead to reiterations in the cell lineages of C. elegans. Cell 1981, 24:59-69.
    • (1981) Cell , vol.24 , pp. 59-69
    • Chalfie, M.1    Horvitz, H.R.2    Sulston, J.E.3
  • 27
    • 69949167191 scopus 로고    scopus 로고
    • Ribosomal protein RPS-14 modulates let-7 microRNA function in Caenorhabditis elegans
    • Chan S.P., Slack F.J. Ribosomal protein RPS-14 modulates let-7 microRNA function in Caenorhabditis elegans. Dev. Biol. 2009, 334:152-160.
    • (2009) Dev. Biol. , vol.334 , pp. 152-160
    • Chan, S.P.1    Slack, F.J.2
  • 28
    • 70349453924 scopus 로고    scopus 로고
    • Active turnover modulates mature microRNA activity in Caenorhabditis elegans
    • Chatterjee S., Groszhans H. Active turnover modulates mature microRNA activity in Caenorhabditis elegans. Nature 2009, 461:546-549.
    • (2009) Nature , vol.461 , pp. 546-549
    • Chatterjee, S.1    Groszhans, H.2
  • 29
    • 79952498226 scopus 로고    scopus 로고
    • Target-mediated protection of endogenous microRNAs in C. elegans
    • Chatterjee S., Fasler M., Büssing I., Großhans H. Target-mediated protection of endogenous microRNAs in C. elegans. Dev. Cell 2011, 20:388-396.
    • (2011) Dev. Cell , vol.20 , pp. 388-396
    • Chatterjee, S.1    Fasler, M.2    Büssing, I.3    Großhans, H.4
  • 30
    • 67749132423 scopus 로고    scopus 로고
    • Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps
    • Chi S.W., Zang J.B., Mele A., Darnell R.B. Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. Nature 2009, 460:479-486.
    • (2009) Nature , vol.460 , pp. 479-486
    • Chi, S.W.1    Zang, J.B.2    Mele, A.3    Darnell, R.B.4
  • 32
    • 79551588017 scopus 로고    scopus 로고
    • Computational and experimental identification of mirtrons in Drosophila melanogaster and Caenorhabditis elegans
    • Chung W.J., Agius P., Westholm J.O., Chen M., Okamura K., Robine N., Leslie C.S., Lai E.C. Computational and experimental identification of mirtrons in Drosophila melanogaster and Caenorhabditis elegans. Genome Res. 2011, 21:286-300.
    • (2011) Genome Res. , vol.21 , pp. 286-300
    • Chung, W.J.1    Agius, P.2    Westholm, J.O.3    Chen, M.4    Okamura, K.5    Robine, N.6    Leslie, C.S.7    Lai, E.C.8
  • 33
    • 78650306521 scopus 로고    scopus 로고
    • Small RNA sorting: Matchmaking for Argonautes
    • Czech B., Hannon G.J. Small RNA sorting: Matchmaking for Argonautes. Nat. Rev. Genet. 2011, 12:19-31.
    • (2011) Nat. Rev. Genet. , vol.12 , pp. 19-31
    • Czech, B.1    Hannon, G.J.2
  • 34
    • 59649089157 scopus 로고    scopus 로고
    • Repression of C. elegans microRNA targets at the initiation level of translation requires GW182 proteins
    • Ding X.C., Groszhans H. Repression of C. elegans microRNA targets at the initiation level of translation requires GW182 proteins. EMBO J. 2009, 28:213-222.
    • (2009) EMBO J. , vol.28 , pp. 213-222
    • Ding, X.C.1    Groszhans, H.2
  • 35
    • 79551627496 scopus 로고    scopus 로고
    • A parsimonious model for gene regulation by miRNAs
    • Djuranovic S., Nahvi A., Green R. A parsimonious model for gene regulation by miRNAs. Science 2011, 331:550-553.
    • (2011) Science , vol.331 , pp. 550-553
    • Djuranovic, S.1    Nahvi, A.2    Green, R.3
  • 36
    • 1642374097 scopus 로고    scopus 로고
    • Specificity of microRNA target selection in translational repression
    • Doench J.G., Sharp P.A. Specificity of microRNA target selection in translational repression. Genes Dev. 2004, 18:504-511.
    • (2004) Genes Dev. , vol.18 , pp. 504-511
    • Doench, J.G.1    Sharp, P.A.2
  • 38
    • 34447521718 scopus 로고    scopus 로고
    • Isolation of microRNA targets by miRNP immunopurification
    • Easow G., Teleman A.A., Cohen S.M. Isolation of microRNA targets by miRNP immunopurification. RNA 2007, 13:1198-1204.
    • (2007) RNA , vol.13 , pp. 1198-1204
    • Easow, G.1    Teleman, A.A.2    Cohen, S.M.3
  • 40
    • 28444441562 scopus 로고    scopus 로고
    • Post-embryonic expression of C. elegans microRNAs belonging to the lin-4 and let-7 families in the hypodermis and the reproductive system
    • Esquela-Kerscher A., Johnson S.M., Bai L., Saito K., Partridge J., Reinert K.L., Slack F.J. Post-embryonic expression of C. elegans microRNAs belonging to the lin-4 and let-7 families in the hypodermis and the reproductive system. Dev. Dyn. 2005, 234:868-877.
    • (2005) Dev. Dyn. , vol.234 , pp. 868-877
    • Esquela-Kerscher, A.1    Johnson, S.M.2    Bai, L.3    Saito, K.4    Partridge, J.5    Reinert, K.L.6    Slack, F.J.7
  • 42
    • 77953629046 scopus 로고    scopus 로고
    • Regulation of mRNA translation and stability by microRNAs
    • Fabian M.R., Sonenberg N., Filipowicz W. Regulation of mRNA translation and stability by microRNAs. Annu. Rev. Biochem. 2010, 79:351-379.
    • (2010) Annu. Rev. Biochem. , vol.79 , pp. 351-379
    • Fabian, M.R.1    Sonenberg, N.2    Filipowicz, W.3
  • 43
    • 79952907985 scopus 로고    scopus 로고
    • The impact of miRNA target sites in coding sequences and in 3'UTRs
    • Fang Z., Rajewsky N. The impact of miRNA target sites in coding sequences and in 3'UTRs. PLoS One 2011, 6:e18067.
    • (2011) PLoS One , vol.6
    • Fang, Z.1    Rajewsky, N.2
  • 44
    • 0033555831 scopus 로고    scopus 로고
    • A Caenorhabditis elegans homologue of hunchback is required for late stages of development but not early embryonic patterning
    • Fay D.S., Stanley H.M., Han M., Wood W.B. A Caenorhabditis elegans homologue of hunchback is required for late stages of development but not early embryonic patterning. Dev. Biol. 1999, 205:240-253.
    • (1999) Dev. Biol. , vol.205 , pp. 240-253
    • Fay, D.S.1    Stanley, H.M.2    Han, M.3    Wood, W.B.4
  • 45
    • 77955152366 scopus 로고    scopus 로고
    • Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression
    • Gehrke S., Imai Y., Sokol N., Lu B. Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression. Nature 2010, 466:637-641.
    • (2010) Nature , vol.466 , pp. 637-641
    • Gehrke, S.1    Imai, Y.2    Sokol, N.3    Lu, B.4
  • 47
    • 14644398601 scopus 로고    scopus 로고
    • The temporal patterning microRNA let-7 regulates several transcription factors at the larval to adult transition in C. elegans
    • Großhans H., Johnson T., Reinert K.L., Gerstein M., Slack F.J. The temporal patterning microRNA let-7 regulates several transcription factors at the larval to adult transition in C. elegans. Dev. Cell 2005, 8:321-330.
    • (2005) Dev. Cell , vol.8 , pp. 321-330
    • Großhans, H.1    Johnson, T.2    Reinert, K.L.3    Gerstein, M.4    Slack, F.J.5
  • 48
    • 59649125888 scopus 로고    scopus 로고
    • Biological basis for restriction of microRNA targets to the 3' untranslated region in mammalian mRNAs
    • Gu S., Jin L., Zhang F., Sarnow P., Kay M.A. Biological basis for restriction of microRNA targets to the 3' untranslated region in mammalian mRNAs. Nat. Struct. Mol. Biol. 2009, 16:144-150.
    • (2009) Nat. Struct. Mol. Biol. , vol.16 , pp. 144-150
    • Gu, S.1    Jin, L.2    Zhang, F.3    Sarnow, P.4    Kay, M.A.5
  • 49
    • 77955644289 scopus 로고    scopus 로고
    • Mammalian microRNAs predominantly act to decrease target mRNA levels
    • Guo H., Ingolia N.T., Weissman J.S., Bartel D.P. Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 2010, 466:835-840.
    • (2010) Nature , vol.466 , pp. 835-840
    • Guo, H.1    Ingolia, N.T.2    Weissman, J.S.3    Bartel, D.P.4
  • 51
    • 70349820140 scopus 로고    scopus 로고
    • Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells
    • Hagan J.P., Piskounova E., Gregory R.I. Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells. Nat. Struct. Mol. Biol. 2009, 16:1021-1025.
    • (2009) Nat. Struct. Mol. Biol. , vol.16 , pp. 1021-1025
    • Hagan, J.P.1    Piskounova, E.2    Gregory, R.I.3
  • 52
    • 50849141708 scopus 로고    scopus 로고
    • MirWIP: MicroRNA target prediction based on microRNA-containing ribonucleoprotein-enriched transcripts
    • Hammell M., Long D., Zhang L., Lee A., Carmack C.S., Han M., Ding Y., Ambros V. mirWIP: MicroRNA target prediction based on microRNA-containing ribonucleoprotein-enriched transcripts. Nat. Methods 2008, 5:813-819.
    • (2008) Nat. Methods , vol.5 , pp. 813-819
    • Hammell, M.1    Long, D.2    Zhang, L.3    Lee, A.4    Carmack, C.S.5    Han, M.6    Ding, Y.7    Ambros, V.8
  • 53
    • 73249148097 scopus 로고    scopus 로고
    • A feedback circuit involving let-7-family miRNAs and DAF-12 integrates environmental signals and developmental timing in Caenorhabditis elegans
    • Hammell C.M., Karp X., Ambros V. A feedback circuit involving let-7-family miRNAs and DAF-12 integrates environmental signals and developmental timing in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 2009, 106:18668-18673.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 18668-18673
    • Hammell, C.M.1    Karp, X.2    Ambros, V.3
  • 54
    • 61349169058 scopus 로고    scopus 로고
    • Nhl-2 modulates microRNA activity in Caenorhabditis elegans
    • Hammell C.M., Lubin I., Boag P.R., Blackwell T.K., Ambros V. nhl-2 modulates microRNA activity in Caenorhabditis elegans. Cell 2009, 136:926-938.
    • (2009) Cell , vol.136 , pp. 926-938
    • Hammell, C.M.1    Lubin, I.2    Boag, P.R.3    Blackwell, T.K.4    Ambros, V.5
  • 55
    • 47749154078 scopus 로고    scopus 로고
    • Systematic identification of mRNAs recruited to argonaute 2 by specific microRNAs and corresponding changes in transcript abundance
    • Hendrickson D.G., Hogan D.J., Herschlag D., Ferrell J.E., Brown P.O. Systematic identification of mRNAs recruited to argonaute 2 by specific microRNAs and corresponding changes in transcript abundance. PLoS One 2008, 3:e2126.
    • (2008) PLoS One , vol.3
    • Hendrickson, D.G.1    Hogan, D.J.2    Herschlag, D.3    Ferrell, J.E.4    Brown, P.O.5
  • 56
    • 53949088050 scopus 로고    scopus 로고
    • Lin28 mediates the terminal uridylation of let-7 precursor microRNA
    • Heo I., Joo C., Cho J., Ha M., Han J., Kim V.N. Lin28 mediates the terminal uridylation of let-7 precursor microRNA. Mol. Cell 2008, 32:276-284.
    • (2008) Mol. Cell , vol.32 , pp. 276-284
    • Heo, I.1    Joo, C.2    Cho, J.3    Ha, M.4    Han, J.5    Kim, V.N.6
  • 57
    • 68749102148 scopus 로고    scopus 로고
    • TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation
    • Heo I., Joo C., Kim Y.K., Ha M., Yoon M.J., Cho J., Yeom K.H., Han J., Kim V.N. TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation. Cell 2009, 138:696-708.
    • (2009) Cell , vol.138 , pp. 696-708
    • Heo, I.1    Joo, C.2    Kim, Y.K.3    Ha, M.4    Yoon, M.J.5    Cho, J.6    Yeom, K.H.7    Han, J.8    Kim, V.N.9
  • 60
    • 78751477191 scopus 로고    scopus 로고
    • Gene silencing by microRNAs: Contributions of translational repression and mRNA decay
    • Huntzinger E., Izaurralde E. Gene silencing by microRNAs: Contributions of translational repression and mRNA decay. Nat. Rev. Genet. 2011, 12:99-110.
    • (2011) Nat. Rev. Genet. , vol.12 , pp. 99-110
    • Huntzinger, E.1    Izaurralde, E.2
  • 61
    • 33947726050 scopus 로고    scopus 로고
    • CRM1-mediated nuclear export: To the pore and beyond
    • Hutten S., Kehlenbach R.H. CRM1-mediated nuclear export: To the pore and beyond. Trends Cell Biol. 2007, 17:193-201.
    • (2007) Trends Cell Biol. , vol.17 , pp. 193-201
    • Hutten, S.1    Kehlenbach, R.H.2
  • 62
    • 77957664647 scopus 로고    scopus 로고
    • MicroRNAs as regulators of differentiation and cell fate decisions
    • Ivey K.N., Srivastava D. MicroRNAs as regulators of differentiation and cell fate decisions. Cell Stem Cell 2010, 7:36-41.
    • (2010) Cell Stem Cell , vol.7 , pp. 36-41
    • Ivey, K.N.1    Srivastava, D.2
  • 63
    • 42449132234 scopus 로고    scopus 로고
    • Two molecular features contribute to the Argonaute specificity for the microRNA and RNAi pathways in C. elegans
    • Jannot G., Boisvert M.E.L., Banville I.H., Simard M.J. Two molecular features contribute to the Argonaute specificity for the microRNA and RNAi pathways in C. elegans. RNA 2008, 14:829-835.
    • (2008) RNA , vol.14 , pp. 829-835
    • Jannot, G.1    Boisvert, M.E.L.2    Banville, I.H.3    Simard, M.J.4
  • 66
    • 0037772254 scopus 로고    scopus 로고
    • The time of appearance of the C. elegans let-7 microRNA is transcriptionally controlled utilizing a temporal regulatory element in its promoter
    • Johnson S.M., Lin S.Y., Slack F.J. The time of appearance of the C. elegans let-7 microRNA is transcriptionally controlled utilizing a temporal regulatory element in its promoter. Dev. Biol. 2003, 259:364-379.
    • (2003) Dev. Biol. , vol.259 , pp. 364-379
    • Johnson, S.M.1    Lin, S.Y.2    Slack, F.J.3
  • 70
    • 77449131843 scopus 로고    scopus 로고
    • MicroRNA assassins: Factors that regulate the disappearance of miRNAs
    • Kai Z.S., Pasquinelli A.E. MicroRNA assassins: Factors that regulate the disappearance of miRNAs. Nat. Struct. Mol. Biol. 2010, 17:5-10.
    • (2010) Nat. Struct. Mol. Biol. , vol.17 , pp. 5-10
    • Kai, Z.S.1    Pasquinelli, A.E.2
  • 71
    • 33645461834 scopus 로고    scopus 로고
    • Cloning and regulation of the vertebrate homologue of lin-41 that functions as a heterochronic gene in Caenorhabditis elegans
    • Kanamoto T., Terada K., Yoshikawa H., Furukawa T. Cloning and regulation of the vertebrate homologue of lin-41 that functions as a heterochronic gene in Caenorhabditis elegans. Dev. Dyn. 2006, 235:1142-1149.
    • (2006) Dev. Dyn. , vol.235 , pp. 1142-1149
    • Kanamoto, T.1    Terada, K.2    Yoshikawa, H.3    Furukawa, T.4
  • 74
    • 34748821761 scopus 로고    scopus 로고
    • The role of site accessibility in microRNA target recognition
    • Kertesz M., Iovino N., Unnerstall U., Gaul U., Segal E. The role of site accessibility in microRNA target recognition. Nat. Genet. 2007, 39:1278-1284.
    • (2007) Nat. Genet. , vol.39 , pp. 1278-1284
    • Kertesz, M.1    Iovino, N.2    Unnerstall, U.3    Gaul, U.4    Segal, E.5
  • 79
    • 77955902024 scopus 로고    scopus 로고
    • The widespread regulation of microRNA biogenesis, function and decay
    • Krol J., Loedige I., Filipowicz W. The widespread regulation of microRNA biogenesis, function and decay. Nat. Rev. Genet. 2010, 11:597-610.
    • (2010) Nat. Rev. Genet. , vol.11 , pp. 597-610
    • Krol, J.1    Loedige, I.2    Filipowicz, W.3
  • 81
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed RNAs
    • Lagos-Quintana M., Rauhut R., Lendeckel W., Tuschl T. Identification of novel genes coding for small expressed RNAs. Science 2001, 294:853-858.
    • (2001) Science , vol.294 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 83
    • 20544465679 scopus 로고    scopus 로고
    • MiRNAs: Whys and wherefores of miRNA-mediated regulation
    • Lai E.C. miRNAs: Whys and wherefores of miRNA-mediated regulation. Curr. Biol. 2005, 15:R458-R460.
    • (2005) Curr. Biol. , vol.15
    • Lai, E.C.1
  • 86
    • 0035955361 scopus 로고    scopus 로고
    • An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    • Lau N.C., Lim L.P., Weinstein E.G., Bartel D.P. An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 2001, 294:858-862.
    • (2001) Science , vol.294 , pp. 858-862
    • Lau, N.C.1    Lim, L.P.2    Weinstein, E.G.3    Bartel, D.P.4
  • 87
    • 57149130694 scopus 로고    scopus 로고
    • MicroRNAs in embryonic stem cells and early embryonic development
    • Laurent L.C. MicroRNAs in embryonic stem cells and early embryonic development. J. Cell. Mol. Med. 2008, 12:2181-2188.
    • (2008) J. Cell. Mol. Med. , vol.12 , pp. 2181-2188
    • Laurent, L.C.1
  • 88
    • 0035955366 scopus 로고    scopus 로고
    • An extensive class of small RNAs in Caenorhabditis elegans
    • Lee R.C., Ambros V. An extensive class of small RNAs in Caenorhabditis elegans. Science 2001, 294:862-864.
    • (2001) Science , vol.294 , pp. 862-864
    • Lee, R.C.1    Ambros, V.2
  • 89
    • 34247565615 scopus 로고    scopus 로고
    • The tumor suppressor microRNA let-7 represses the HMGA2 oncogene
    • Lee Y.S., Dutta A. The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. Genes Dev. 2007, 21:1025-1030.
    • (2007) Genes Dev. , vol.21 , pp. 1025-1030
    • Lee, Y.S.1    Dutta, A.2
  • 90
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee R.C., Feinbaum R.L., Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993, 75:843-854.
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 94
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis B.P., Burge C.B., Bartel D.P. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005, 120:15-20.
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 99
    • 58049208169 scopus 로고    scopus 로고
    • The let-7 microRNA target gene, Mlin41/Trim71 is required for mouse embryonic survival and neural tube closure
    • Maller-Schulman B.R., Liang X., Stahlhut C., DelConte C., Stefani G., Slack F.J. The let-7 microRNA target gene, Mlin41/Trim71 is required for mouse embryonic survival and neural tube closure. Cell Cycle 2008, 7:3935-3942.
    • (2008) Cell Cycle , vol.7 , pp. 3935-3942
    • Maller-Schulman, B.R.1    Liang, X.2    Stahlhut, C.3    DelConte, C.4    Stefani, G.5    Slack, F.J.6
  • 101
    • 33947431322 scopus 로고    scopus 로고
    • Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation
    • Mayr C., Hemann M.T., Bartel D.P. Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation. Science 2007, 315:1576-1579.
    • (2007) Science , vol.315 , pp. 1576-1579
    • Mayr, C.1    Hemann, M.T.2    Bartel, D.P.3
  • 102
    • 79960015284 scopus 로고    scopus 로고
    • MicroRNA regulation of embryonic stem cell self-renewal and differentiation
    • Springer, USA, E. Meshorer, K. Plath (Eds.)
    • Melton C., Blelloch R. MicroRNA regulation of embryonic stem cell self-renewal and differentiation. The Cell Biology of Stem Cells 2010, 105-117. Springer, USA. E. Meshorer, K. Plath (Eds.).
    • (2010) The Cell Biology of Stem Cells , pp. 105-117
    • Melton, C.1    Blelloch, R.2
  • 103
    • 0018471126 scopus 로고
    • Lethals, steriles and deficiencies in a region of the X chromosome of Caenorhabditis elegans
    • Meneely P.M., Herman R.K. Lethals, steriles and deficiencies in a region of the X chromosome of Caenorhabditis elegans. Genetics 1979, 92:99-115.
    • (1979) Genetics , vol.92 , pp. 99-115
    • Meneely, P.M.1    Herman, R.K.2
  • 104
    • 33748587841 scopus 로고    scopus 로고
    • A pattern-based method for the identification of microRNA binding sites and their corresponding heteroduplexes
    • Miranda K.C., Huynh T., Tay Y., Ang Y.S., Tam W.L., Thomson A.M., Lim B., Rigoutsos I. A pattern-based method for the identification of microRNA binding sites and their corresponding heteroduplexes. Cell 2006, 126:1203-1217.
    • (2006) Cell , vol.126 , pp. 1203-1217
    • Miranda, K.C.1    Huynh, T.2    Tay, Y.3    Ang, Y.S.4    Tam, W.L.5    Thomson, A.M.6    Lim, B.7    Rigoutsos, I.8
  • 106
    • 0030970775 scopus 로고    scopus 로고
    • The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA
    • Moss E.G., Lee R.C., Ambros V. The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA. Cell 1997, 88:637-646.
    • (1997) Cell , vol.88 , pp. 637-646
    • Moss, E.G.1    Lee, R.C.2    Ambros, V.3
  • 108
    • 41749116632 scopus 로고    scopus 로고
    • The evolution of core proteins involved in microRNA biogenesis
    • Murphy D., Dancis B., Brown J. The evolution of core proteins involved in microRNA biogenesis. BMC Evol. Biol. 2008, 8:92.
    • (2008) BMC Evol. Biol. , vol.8 , pp. 92
    • Murphy, D.1    Dancis, B.2    Brown, J.3
  • 109
    • 47949100595 scopus 로고    scopus 로고
    • Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing
    • Newman M.A., Thomson J.M., Hammond S.M. Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing. RNA 2008, 14:1539-1549.
    • (2008) RNA , vol.14 , pp. 1539-1549
    • Newman, M.A.1    Thomson, J.M.2    Hammond, S.M.3
  • 110
    • 67649556287 scopus 로고    scopus 로고
    • An elegant miRror: MicroRNAs in stem cells, developmental timing and cancer
    • Nimmo R., Slack F. An elegant miRror: MicroRNAs in stem cells, developmental timing and cancer. Chromosoma 2009, 118:405-418.
    • (2009) Chromosoma , vol.118 , pp. 405-418
    • Nimmo, R.1    Slack, F.2
  • 111
    • 53749098061 scopus 로고    scopus 로고
    • Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf expression
    • Nishino J., Kim I., Chada K., Morrison S.J. Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf expression. Cell 2008, 135:227-239.
    • (2008) Cell , vol.135 , pp. 227-239
    • Nishino, J.1    Kim, I.2    Chada, K.3    Morrison, S.J.4
  • 112
  • 113
    • 34447107760 scopus 로고    scopus 로고
    • The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila
    • Okamura K., Hagen J.W., Duan H., Tyler D.M., Lai E.C. The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila. Cell 2007, 130:89-100.
    • (2007) Cell , vol.130 , pp. 89-100
    • Okamura, K.1    Hagen, J.W.2    Duan, H.3    Tyler, D.M.4    Lai, E.C.5
  • 114
    • 41649089309 scopus 로고    scopus 로고
    • The regulatory activity of microRNA* species has substantial influence on microRNA and 3' UTR evolution
    • Okamura K., Phillips M.D., Tyler D.M., Duan H., Chou Y.t, Lai E.C. The regulatory activity of microRNA* species has substantial influence on microRNA and 3' UTR evolution. Nat. Struct. Mol. Biol. 2008, 15:354-363.
    • (2008) Nat. Struct. Mol. Biol. , vol.15 , pp. 354-363
    • Okamura, K.1    Phillips, M.D.2    Tyler, D.M.3    Duan, H.4    Chou, Y.5    Lai, E.C.6
  • 115
    • 0033572284 scopus 로고    scopus 로고
    • The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation
    • Olsen P.H., Ambros V. The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation. Dev. Biol. 1999, 216:671-680.
    • (1999) Dev. Biol. , vol.216 , pp. 671-680
    • Olsen, P.H.1    Ambros, V.2
  • 116
    • 78650194092 scopus 로고    scopus 로고
    • Let-7 and miR-17-92: Small-sized major players in lung cancer development
    • Osada H., Takahashi T. let-7 and miR-17-92: Small-sized major players in lung cancer development. Cancer Sci. 2011, 102:9-17.
    • (2011) Cancer Sci. , vol.102 , pp. 9-17
    • Osada, H.1    Takahashi, T.2
  • 120
    • 70349276702 scopus 로고    scopus 로고
    • Transcription of the C. elegans let-7 microRNA is temporally regulated by one of its targets, hbl-1
    • Roush S.F., Slack F.J. Transcription of the C. elegans let-7 microRNA is temporally regulated by one of its targets, hbl-1. Dev. Biol. 2009, 334:523-534.
    • (2009) Dev. Biol. , vol.334 , pp. 523-534
    • Roush, S.F.1    Slack, F.J.2
  • 121
    • 33845436047 scopus 로고    scopus 로고
    • Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans
    • Ruby J.G., Jan C., Player C., Axtell M.J., Lee W., Nusbaum C., Ge H., Bartel D.P. Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans. Cell 2006, 127:1193-1207.
    • (2006) Cell , vol.127 , pp. 1193-1207
    • Ruby, J.G.1    Jan, C.2    Player, C.3    Axtell, M.J.4    Lee, W.5    Nusbaum, C.6    Ge, H.7    Bartel, D.P.8
  • 122
    • 34447097693 scopus 로고    scopus 로고
    • Intronic microRNA precursors that bypass Drosha processing
    • Ruby J.G., Jan C.H., Bartel D.P. Intronic microRNA precursors that bypass Drosha processing. Nature 2007, 448:83-86.
    • (2007) Nature , vol.448 , pp. 83-86
    • Ruby, J.G.1    Jan, C.H.2    Bartel, D.P.3
  • 123
    • 38149071979 scopus 로고    scopus 로고
    • Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs
    • Ruby J.G., Stark A., Johnston W.K., Kellis M., Bartel D.P., Lai E.C. Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs. Genome Res. 2007, 17:1850-1864.
    • (2007) Genome Res. , vol.17 , pp. 1850-1864
    • Ruby, J.G.1    Stark, A.2    Johnston, W.K.3    Kellis, M.4    Bartel, D.P.5    Lai, E.C.6
  • 124
    • 0024976940 scopus 로고
    • The Caenorhabditis elegans heterochronic gene lin-14 encodes a nuclear protein that forms a temporal developmental switch
    • Ruvkun G., Giusto J. The Caenorhabditis elegans heterochronic gene lin-14 encodes a nuclear protein that forms a temporal developmental switch. Nature 1989, 338:313-319.
    • (1989) Nature , vol.338 , pp. 313-319
    • Ruvkun, G.1    Giusto, J.2
  • 125
    • 48649103982 scopus 로고    scopus 로고
    • A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment
    • Rybak A., Fuchs H., Smirnova L., Brandt C., Pohl E.E., Nitsch R., Wulczyn F.G. A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment. Nat. Cell Biol. 2008, 10:987-993.
    • (2008) Nat. Cell Biol. , vol.10 , pp. 987-993
    • Rybak, A.1    Fuchs, H.2    Smirnova, L.3    Brandt, C.4    Pohl, E.E.5    Nitsch, R.6    Wulczyn, F.G.7
  • 128
    • 61349191567 scopus 로고    scopus 로고
    • The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors
    • Schwamborn J.C., Berezikov E., Knoblich J.A. The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors. Cell 2009, 136:913-925.
    • (2009) Cell , vol.136 , pp. 913-925
    • Schwamborn, J.C.1    Berezikov, E.2    Knoblich, J.A.3
  • 130
    • 1942494040 scopus 로고    scopus 로고
    • Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation
    • Sempere L., Freemantle S., Pitha-Rowe I., Moss E., Dmitrovsky E., Ambros V. Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol. 2004, 5:R13.
    • (2004) Genome Biol. , vol.5
    • Sempere, L.1    Freemantle, S.2    Pitha-Rowe, I.3    Moss, E.4    Dmitrovsky, E.5    Ambros, V.6
  • 133
    • 5444251227 scopus 로고    scopus 로고
    • Identification of C. elegans DAF-12-binding sites, response elements, and target genes
    • Shostak Y., Van Gilst M.R., Antebi A., Yamamoto K.R. Identification of C. elegans DAF-12-binding sites, response elements, and target genes. Genes Dev. 2004, 18:2529-2544.
    • (2004) Genes Dev. , vol.18 , pp. 2529-2544
    • Shostak, Y.1    Van Gilst, M.R.2    Antebi, A.3    Yamamoto, K.R.4
  • 134
    • 0032410209 scopus 로고    scopus 로고
    • A novel repeat domain that is often associated with RING finger and B-box motifs
    • Slack F.J., Ruvkun G. A novel repeat domain that is often associated with RING finger and B-box motifs. Trends Biochem. Sci. 1998, 23:474-475.
    • (1998) Trends Biochem. Sci. , vol.23 , pp. 474-475
    • Slack, F.J.1    Ruvkun, G.2
  • 135
    • 0033634943 scopus 로고    scopus 로고
    • The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor
    • Slack F.J., Basson M., Liu Z., Ambros V., Horvitz H.R., Ruvkun G. The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. Mol. Cell 2000, 5:659-669.
    • (2000) Mol. Cell , vol.5 , pp. 659-669
    • Slack, F.J.1    Basson, M.2    Liu, Z.3    Ambros, V.4    Horvitz, H.R.5    Ruvkun, G.6
  • 137
    • 45349099216 scopus 로고    scopus 로고
    • Drosophila let-7 microRNA is required for remodeling of the neuromusculature during metamorphosis
    • Sokol N.S., Xu P., Jan Y.-N., Ambros V. Drosophila let-7 microRNA is required for remodeling of the neuromusculature during metamorphosis. Genes Dev. 2008, 22:1591-1596.
    • (2008) Genes Dev. , vol.22 , pp. 1591-1596
    • Sokol, N.S.1    Xu, P.2    Jan, Y.-N.3    Ambros, V.4
  • 141
    • 0017618537 scopus 로고
    • Post-embryonic cell lineages of the nematode, Caenorhabditis elegans
    • Sulston J.E., Horvitz H.R. Post-embryonic cell lineages of the nematode, Caenorhabditis elegans. Dev. Biol. 1977, 56:110-156.
    • (1977) Dev. Biol. , vol.56 , pp. 110-156
    • Sulston, J.E.1    Horvitz, H.R.2
  • 143
    • 77951622022 scopus 로고    scopus 로고
    • Role of GW182 proteins and PABPC1 in the miRNA pathway: A sense of deja vu
    • Tritschler F., Huntzinger E., Izaurralde E. Role of GW182 proteins and PABPC1 in the miRNA pathway: A sense of deja vu. Nat. Rev. Mol. Cell Biol. 2010, 11:379-384.
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 379-384
    • Tritschler, F.1    Huntzinger, E.2    Izaurralde, E.3
  • 145
    • 0942301280 scopus 로고    scopus 로고
    • The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3'UTR
    • Vella M.C., Choi E.-Y., Lin S.-Y., Reinert K., Slack F.J. The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3'UTR. Genes Dev. 2004, 18:132-137.
    • (2004) Genes Dev. , vol.18 , pp. 132-137
    • Vella, M.C.1    Choi, E.-Y.2    Lin, S.-Y.3    Reinert, K.4    Slack, F.J.5
  • 146
    • 10644253787 scopus 로고    scopus 로고
    • Architecture of a validated microRNA::target interaction
    • Vella M.C., Reinert K., Slack F.J. Architecture of a validated microRNA::target interaction. Chem. Biol. 2004, 11:1619-1623.
    • (2004) Chem. Biol. , vol.11 , pp. 1619-1623
    • Vella, M.C.1    Reinert, K.2    Slack, F.J.3
  • 147
    • 77049099101 scopus 로고    scopus 로고
    • Lin28: A microRNA regulator with a macro role
    • Viswanathan S.R., Daley G.Q. Lin28: A microRNA regulator with a macro role. Cell 2010, 140:445-449.
    • (2010) Cell , vol.140 , pp. 445-449
    • Viswanathan, S.R.1    Daley, G.Q.2
  • 148
    • 40849108663 scopus 로고    scopus 로고
    • Selective blockade of microRNA processing by Lin28
    • Viswanathan S.R., Daley G.Q., Gregory R.I. Selective blockade of microRNA processing by Lin28. Science 2008, 320:97-100.
    • (2008) Science , vol.320 , pp. 97-100
    • Viswanathan, S.R.1    Daley, G.Q.2    Gregory, R.I.3
  • 149
    • 33847323881 scopus 로고    scopus 로고
    • DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal
    • Wang Y., Medvid R., Melton C., Jaenisch R., Blelloch R. DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal. Nat. Genet. 2007, 39:380-385.
    • (2007) Nat. Genet. , vol.39 , pp. 380-385
    • Wang, Y.1    Medvid, R.2    Melton, C.3    Jaenisch, R.4    Blelloch, R.5
  • 150
    • 0027730383 scopus 로고
    • Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
    • Wightman B., Ha I., Ruvkun G. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 1993, 75:855-862.
    • (1993) Cell , vol.75 , pp. 855-862
    • Wightman, B.1    Ha, I.2    Ruvkun, G.3
  • 151
    • 27144475302 scopus 로고    scopus 로고
    • Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells
    • Wu L., Belasco J.G. Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells. Mol. Cell. Biol. 2005, 25:9198-9208.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 9198-9208
    • Wu, L.1    Belasco, J.G.2
  • 154
    • 0347361541 scopus 로고    scopus 로고
    • Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
    • Yi R., Qin Y., Macara I.G., Cullen B.R. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev. 2003, 17:3011-3016.
    • (2003) Genes Dev. , vol.17 , pp. 3011-3016
    • Yi, R.1    Qin, Y.2    Macara, I.G.3    Cullen, B.R.4
  • 156
    • 0041691111 scopus 로고    scopus 로고
    • MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms
    • Zeng Y., Yi R., Cullen B.R. MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms. Proc. Natl. Acad. Sci. USA 2003, 100:9779-9784.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 9779-9784
    • Zeng, Y.1    Yi, R.2    Cullen, B.R.3
  • 157
    • 36249012075 scopus 로고    scopus 로고
    • Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2
    • Zhang L., Ding L., Cheung T.H., Dong M.-Q., Chen J., Sewell A.K., Liu X., Yates Iii J.R., Han M. Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2. Mol. Cell 2007, 28:598-613.
    • (2007) Mol. Cell , vol.28 , pp. 598-613
    • Zhang, L.1    Ding, L.2    Cheung, T.H.3    Dong, M.-Q.4    Chen, J.5    Sewell, A.K.6    Liu, X.7    Yates Iii, J.R.8    Han, M.9
  • 158
    • 70350038073 scopus 로고    scopus 로고
    • Systematic analysis of dynamic miRNA-target interactions during C. elegans development
    • Zhang L., Hammell M., Kudlow B.A., Ambros V., Han M. Systematic analysis of dynamic miRNA-target interactions during C. elegans development. Development 2009, 136:3043-3055.
    • (2009) Development , vol.136 , pp. 3043-3055
    • Zhang, L.1    Hammell, M.2    Kudlow, B.A.3    Ambros, V.4    Han, M.5
  • 159
    • 76649088031 scopus 로고    scopus 로고
    • MicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling
    • Zhao C., Sun G., Li S., Lang M.-F., Yang S., Li W., Shi Y. MicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling. Proc. Natl. Acad. Sci. USA 2010, 107:1876-1881.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 1876-1881
    • Zhao, C.1    Sun, G.2    Li, S.3    Lang, M.-F.4    Yang, S.5    Li, W.6    Shi, Y.7
  • 161
    • 82355172516 scopus 로고    scopus 로고
    • Comprehensive identification of miRNA target sites in live animals
    • Zisoulis D.G., Yeo G.W., Pasquinelli A.E. Comprehensive identification of miRNA target sites in live animals. Methods Mol. Biol. 2011, 732:169-185.
    • (2011) Methods Mol. Biol. , vol.732 , pp. 169-185
    • Zisoulis, D.G.1    Yeo, G.W.2    Pasquinelli, A.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.