Viral-associated trichodysplasia: Characterization of a novel polyomavirus infection with therapeutic insights

Archives of Dermatology

Volumn 148, Issue 2, 2012, Pages 219-223

  Wanat, Karolyn A ^a   Holler, Phillip D ^a   Dentchev, Tzvete ^a   Simbiri, Kenneth ^a   Robertson, Erle ^a   Seykora, John T ^a   Rosenbach, Misha ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIDOFOVIR; CIMETIDINE; HYDROCORTISONE; IMIQUIMOD; SALICYLIC ACID;

ADULT; ALOPECIA; ARTICLE; CASE REPORT; DRY SKIN; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; PAPULE; PHYSICAL EXAMINATION; POLYOMA VIRUS; POLYOMAVIRUS INFECTION; PRIORITY JOURNAL; SKIN BIOPSY; SKIN DISEASE; VERRUCA VULGARIS; VIRAL ASSOCIATED TRICHODYSPLASIA;

ANTIVIRAL AGENTS; CYTOSINE; DNA, VIRAL; FEMALE; HAIR DISEASES; HAIR FOLLICLE; HUMANS; MIDDLE AGED; PHOSPHONIC ACIDS; POLYOMAVIRUS; POLYOMAVIRUS INFECTIONS;

EID: 84857403063     PISSN: 0003987X     EISSN: 15383652     Source Type: Journal    
DOI: 10.1001/archdermatol.2011.1413     Document Type: Article

References (19)

1. Bollag B, Prins C, Snyder EL, Frisque RJ. Purified JC virus T and T' proteins differentially interact with the retinoblastoma family of tumor suppressor proteins. Virology. 2000;274(1):165-178. (Pubitemid 30650691)
2. van der Meijden E, Janssens RW, Lauber C, Bouwes Bavinck JN, Gorbalenya AE, Feltkamp MC. Discovery of a new human polyomavirus associated with trichodysplasia spinulosa in an immunocompromized patient. PLoS Pathog. 2010; 6(7):e1001024.
3. Matthews MR, Wang RC, Reddick RL, Saldivar VA, Browning JC. Viral-associated trichodysplasia spinulosa: a case with electron microscopic and molecular detection of the trichodysplasia spinulosa-associated human polyomavirus. J Cutan Pathol. 2011;38(5):420-431.
4. Osswald SS, Kulick KB, Tomaszewski MM, Sperling LC. Viral-associated trichodysplasia in a patient with lymphoma: a case report and review. J Cutan Pathol. 2007;34(9):721-725. (Pubitemid 47256249)
5. Haycox CL, Kim S, Fleckman P, et al. Trichodysplasia spinulosa-a newly described folliculocentric viral infection in an immunocompromised host. J Investig Dermatol Symp Proc. 1999;4(3):268-271. (Pubitemid 30085818)
6. Chastain MA,Millikan LE. Pilomatrix dysplasia in an immunosuppressed patient. J Am Acad Dermatol. 2000;43(1, pt 1):118-122. (Pubitemid 30439724)
7. Heaphy MR Jr, Shamma HN, Hickmann M, White MJ. Cyclosporine-induced folliculodystrophy. J Am Acad Dermatol. 2004;50(2):310-315. (Pubitemid 38174297)
8. Sperling LC, Tomaszewski MM, Thomas DA. Viral-associated trichodysplasia in patients who are immunocompromised. J Am Acad Dermatol. 2004;50(2): 318-322. (Pubitemid 38174299)
9. Wyatt AJ, Sachs DL, Shia J, Delgado R, Busam KJ. Virus-associated trichodysplasia spinulosa. Am J Surg Pathol. 2005;29(2):241-246. (Pubitemid 40170643)
10. Campbell RM, Ney A, Gohh R, Robinson-Bostom L. Spiny hyperkeratotic projections on the face and extremities of a kidney transplant recipient. Arch Dermatol. 2006;142(12):1643-1648. (Pubitemid 44969227)
11. Sadler GM, Halbert AR, Smith N, Rogers M. Trichodysplasia spinulosa associated with chemotherapy for acute lymphocytic leukaemia. Australas J Dermatol. 2007;48(2):110-114. (Pubitemid 46802052)
12. Holzer AM, Hughey LC. Trichodysplasia of immunosuppression treated with oral valganciclovir. J Am Acad Dermatol. 2009;60(1):169-172.
13. Benoit T, Bacelieri R, Morrell DS, Metcalf J. Viral-associated trichodysplasia of immunosuppression: report of a pediatric patient with response to oral valganciclovir. Arch Dermatol. 2010;146(8):871-874.
14. Schwieger-Briel A, Balma-Mena A, Ngan B, Dipchand A, Pope E. Trichodysplasia spinulosa-a rare complication in immunosuppressed patients. Pediatr Dermatol. 2010;27(5):509-513.
15. Blake BP, Marathe KS, Mohr MR, Jones N, Novosel T. Viral-associated trichodysplasia of immunosuppression in a renal transplant patient. J Drugs Dermatol. 2011;10(4):422-424.
16. Lee JS, Frederiksen P, Kossard S. Progressive trichodysplasia spinulosa in a patient with chronic lymphocytic leukaemia in remission. Australas J Dermatol. 2008; 49(1):57-60.
17. Elaba ZHS, Andrea A. Trichyodysplasia spinulosa in a lung transplant patient. Poster presented at: American Society of Dermatopathology 47th Annual Meeting; October 7-10, 2010; Atlanta, Georgia.
18. Büchen-Osmond C. Taxonomy and Classification of Viruses. Vol 2. 8th ed. Washington, DC: ASM Press; 2003.
19. Izakovic JBS, Büchner SA, Düggelin M, Guggenheim R, Itin PH. Hair-like hyperkeratoses in patients with kidney transplants: a new cyclosporin side-effect. Hautarzt. 1995;46(12):841-846.